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| 1 | Effectiveness of Inactivated COVID-19 Vaccines Against Symptomatic,Pneumonia,and Severe Disease Caused by the Delta Variant:Real World Study and Evidence—China,2021显示文摘Summary What is already known about this topic?Effectiveness of China’s 2 inactivated vaccines(BBIBPCorV and CoronaVac)against pre-Delta severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)variants ranged from 47%to over 90%,depending on the clinical endpoint,and with greater effectiveness against more severe coronavirus disease 2019(COVID-19).During an outbreak in Guangdong,inactivated vaccine effectiveness(VE)against the Delta variant was 70%for symptomatic infection and 100%for severe COVID-19.However,separate or combined VE estimates for the two inactivated vaccines against Delta are not available.What is added by this report?In an outbreak that started in a hospital,VEs of completed primary vaccination with inactivated COVID-19 vaccines against symptomatic COVID-19,COVID-19 pneumonia,and severe COVID-19 caused by the Delta variant were 51%,61%,and 82%.Completed primary vaccination reduced the risk of progressing from mild to moderate or severe COVID-19 by 74%.VE estimates for BBIBP-CorV and CoronaVac or combined vaccination were similar,and partial vaccination was ineffective.What are the implications for public health practice?Completed primary vaccination with either of the 2 inactivated COVID-19 vaccines reduces risk of symptomatic COVID-19,COVID-19 pneumonia,and severe COVID-19 caused by the Delta variant.Completion of the completed primary vaccination with two doses is necessary for protection from Delta. | Dan Wu Yanyang Zhang Lin Tang Fuzhen Wang Ying Ye Chao Ma Hui Zheng Wenzhou Yu Lei Cao Yifan Song Abuduwaili Reyimu Xiaoxiao Zhang Haifeng Wang Yifei Nie Mingxia Lu Muge Qi Jun Li Ruolin Wang Kaichao Yang Changshuang Wang Lawrence Everett Rodewald Geroge Fu Gao Zhijie An Zundong Yin | 2022 | China CDC weekly2022，4，4： | 7 |
| 2 | Combined pretreatment using CaO and liquid fraction of digestate of rice straw: Anaerobic digestion performance and electron transfer显示文摘To improve anaerobic digestion(AD)efficiency of rice straw,solid alkaline CaO and the liquid fraction of digestate(LFD)were used as pretreatment agents of rice straw.The results showed that AD performance of rice straw with CaOLFD pretreatment was optimal in different pretreatment methods of the CaO+LFD,CaOLFD,LFD+CaO,CaO,and LFD.The maximum methane yield(314 ml(g VS)^(-1))and the highest VFAs concentration(14851 mg·L^(-1) on day 3)of the CaOLFD pretreatment group were 81%and 118%higher than that of the control group,respectively.Under the action of solid alkaline CaO,the bacteria of Clostridium,Atopostipes,Sphaerochaeta,Tissierella,Thiopseudomonas,Rikenellaceae,and Sedimentibacter could build up co-cultures with the archaeal of Methanosaeta,Methanobacterium,and Methanosarcina performing direct interspecies electron transfer(DIET)and improving AD performance of rice straw.Therefore,the combined pretreatment using CaO and LFD could not only pretreat rice straw but also stimulate co-cultures of microorganism to establish DIET enhancing AD efficiency. | Ruolin Guan Hairong Yuan Liang Zhang Xiaoyu Zuo Xiujin Li | 2021 | Chinese Journal of Chemical Engineering2021，34，8： | 5 |
| 3 | Automatic Modulation Recognition Based on CNN and GRU显示文摘Based on a comparative analysis of the Long Short-Term Memory(LSTM)and Gated Recurrent Unit(GRU)networks,we optimize the structure of the GRU network and propose a new modulation recognition method based on feature extraction and a deep learning algorithm.High-order cumulant,Signal-to-Noise Ratio(SNR),instantaneous feature,and the cyclic spectrum of signals are extracted firstly,and then input into the Convolutional Neural Network(CNN)and the parallel network of GRU for recognition.Eight modulation modes of communication signals are recognized automatically.Simulation results show that the proposed method can achieve high recognition rate at low SNR. | Fugang Liu Ziwei Zhang Ruolin Zhou | 2022 | Tsinghua Science and Technology2022，27，2： | 5 |
| 4 | Effect of dexamethasone on intelligence and hearing in preterm infants: a meta-analysis显示文摘OBJECTIVE: A meta-analysis of published randomized controlled trials investigating the longterm effect of dexamethasone on the nervous system of preterm infants.DATA SOURCES: Online literature retrieval was conducted using The Cochrane Library(from January 1993 to June 2013), EMBASE(from January 1980 to June 2013), MEDLINE(from January 1963 to June 2013), OVID(from January 1993 to June 2013), Springer(from January 1994 to June 2013) and Chinese Academic Journal Full-text Database(from January 1994 to June 2013). Key words were preterm infants and dexamethasone in English and Chinese.STUDY SELECTION: Selected studies were randomized controlled trials assessing the effect of intravenous dexamethasone in preterm infants. The quality of the included papers was evaluated and those without the development of the nervous system and animal experiments were excluded. Quality assessment was performed through bias risk evaluation in accordance with Cochrane Handbook 5.1.0 software in the Cochrane Collaboration. The homogeneous studies were analyzed and compared using Revman 5.2.6 software, and then effect model was selected and analyzed. Those papers failed to be included in the meta-analysis were subjected to descriptive analysis.MAIN OUTCOME MEASURES: Nervous system injury in preterm infants.RESULTS: Ten randomized controlled trials were screened, involving 1,038 subjects. Among them 512 cases received dexamethasone treatment while 526 cases served as placebo control group and blank control group. Meta-analysis results showed that the incidence of cerebral palsy, visual impairment and hearing loss in preterm infants after dexamethasone treatment within 7 days after birth was similar to that in the control group(RR = 1.47, 95%CI: 0.97–2.21; RR = 1.46, 95%CI: 0.97–2.20; RR = 0.80, 95%CI: 0.54–1.18; P > 0.05), but intelligence quotient was significantly decreased compared with the control group(MD =-3.55, 95%CI:-6.59 to-0.51; P = 0.02). Prete rm infants treated with dexamethasone 7 days after birth demonstrated an incidence of cerebral palsy and visual impairment, and changes in intelligence quotient similar to those in the control group(RR = 1.26, 95%CI: 0.89–1.79; RR = 1.37, 95%CI: 0.73–2.59; RR = 0.53, 95%CI: 0.32–0.89; RR = 1.66, 95%CI:-4.7 to 8.01; P > 0.05). However, the incidence of hearing loss was significantly increased compared with that in the control group(RR = 0.53, 95%CI: 0.32–0.89; P = 0.02).CONCLUSION: Dexamethasone may affect the intelligence of preterm infants in the early stages after birth, but may lead to hearing impairment at later stages after birth. More reliable conclusions should be made through large-size, multi-center, well-designed randomized controlled trials. | Ruolin Zhang Tao Bo Li Shen Senlin Luo Jian Li | 2014 | Neural Regeneration Research2014，9，6： | 3 |
| 5 | Supplement to the published paper'Theory-guided interventions for Chinese patients to adapt to heart failure:A quasi-experimental study'显示文摘We appreciate the question raised in a discussion with a reader and the editor about an instrument for outcome measure of the quality of life among people with chronic heart failure[1].We recognized that we should have described more details about how to convert the score of the Minnesota Living with Heart Failure Questionnaire(MLHFQ).Lack of scoring details might lead to some confusion to understand the results of this study.We thank the International Journal of Nursing Sciences for the opportunity to provide further information to clarify the process of data analysis and research findings. | Xiyi Wang Leiwen Tang Doris Howell Qi Zhang Ruolin Qiu Hui Zhang Zhihong Ye | 2021 | International Journal of Nursing Sciences2021，8，2： | 3 |
| 6 | Structural and temporal dynamics analysis on drug-eluting stents: History, research hotspots and emerging trends显示文摘Purpose:This review aims to explore the history,research hotspots,and emerging trends of drug-eluting stents(DES)in the last two decades from the perspective of structural and temporal dynamics.Methods:Publications on DES were retrieved from WoSCC.The bibliometric tools including CiteSpace and HistCite were used to identify the historical features,the evolution of active topics,and emerging trends on the DES field.Results:In the last 20 years,the field of DES is still in the hot phase and there is a wide range of extensive scientific collaborations.In addition,active topics emerge in different periods,as evidenced by a total of 41 disciplines,511 keywords,and 1377 papers with citation bursts.Keyword clustering anchored five emerging research subfields,namely#0 dual antiplatelet therapy,#3 drug-coated balloon,#4 bifurcation,5#rotational atherectomy,and 6#quantitative flow ratio.The keyword alluvial map shows that the most persistent research concepts in this field are thrombosis,restenosis,etc.,and the emerging keywords are paclitaxel eluting balloon,coated balloon,drug-eluting balloon,etc.There are 7 recent research subfields anchored by reference clustering,namely#2 dual antiplatelet therapy,#4 drug-coated balloon,#5 peripheral artery disease,#8 fractional flow reserve,#10 bioresorbable vascular scaffold,#13 intravascular ultrasound,#14 biodegradable polymer.Conclusion:The findings based on the bibliometric studies provide the current status and trends in DES research and may help researchers to identify hot topics and explore new research directions in this field. | Lili Tan Xiangxiu Wang Kungshan Yuan Tieying Yin Ruolin Du Li Shen Zhirong Zhu Suhua Yu Haijun Zhang Guixue Wang | 2023 | Bioactive Materials2023，，5： | 2 |
| 7 | Object tracking and detecting based on adaptive background subtraction 显示文摘 | ZHANG Ruolin DING Jian | 2012 | Procedia Engineering2012，，29： | 1 |
| 8 | Object tracking and detecting based on adaptive background subtraction显示文摘 | Zhang Ruolin Ding Jian | 2012 | Procedia Engineering2012，29，： | 1 |
| 9 | Object tracking and detecting based on adaptive background subtraction 显示文摘 | Zhang Ruolin Ding Jian | 2012 | Procedia Engineering2012，29，： | 1 |
| 10 | Genome Size Evolution Mediated by Gypsy Retrotransposons in Brassicaceae显示文摘The dynamic activity of transposable elements(TEs)contributes to the vast diversity of genome size and architecture among plants.Here,we examined the genomic distribution and transposition activity of long terminal repeat retrotransposons(LTR-RTs)in Arabidopsis thaliana(Ath)and three of its relatives,Arabidopsis lyrata(Aly),Eutrema salsugineum(Esa),and Schrenkiella parvula(Spa),in Brassicaceae.Our analyses revealed the distinct evolutionary dynamics of Gypsy retrotransposons,which reflects the different patterns of genome size changes of the four species over the past million years.The rate of Gypsy transposition in Aly is approximately five times more rapid than that of Ath and Esa,suggesting an expanding Aly genome.Gypsy insertions in Esa are strictly confined to pericentromeric heterochromatin and associated with dramatic centromere expansion.In contrast,Gypsy insertions in Spa have been largely suppressed over the last million years,likely as a result of a combination of an inherent molecular mechanism of preferential DNA removal and purifying selection at Gypsy elements.Additionally,species-specific clades of Gypsy elements shaped the distinct genome architectures of Aly and Esa. | Shi-Jian Zhang Lei Liu Ruolin Yang Xiangfeng Wang | 2020 | Genomics, Proteomics & Bioinformatics2020，18，3： | 1 |
| 11 | Object tracking and detecting based on adaptive background subtraction 显示文摘 | Zhang Ruolin Ding Jian | 2012 | Procedia Engineer- ing2012，29，： | 1 |
| 12 | The Janus-faced role of Piezo1 in cardiovascular health under mechanical stimulation显示文摘In recent years,cardiovascular health problems are becoming more and more serious.At the same time,mechanical stimulation closely relates to cardiovascular health.In this context,Piezo1,which is very sensitive to mechanical stimulation,has attracted our attention.Here,we review the critical significance of Piezo1 in mechanical stimulation of endothelial cells,NO production,lipid metabolism,DNA damage protection,the development of new blood vessels and maturation,narrowing of blood vessels,blood pressure regulation,vascular permeability,insulin sensitivity,and maintenance of red blood cell function.Besides,Piezo1 may participate in the occurrence and development of atherosclerosis,diabetes,hypertension,and other cardiovascular diseases.It is worth noting that Piezo1 has dual effects on maintaining cardiovascular health.On the one hand,the function of Piezo1 is necessary to maintain cardiovascular health;on the other hand,under some extreme mechanical stimulation,the overexpression of Piezo1 may bring adverse factors such as inflammation.Therefore,this review discusses the Janus-faced role of Piezo1 in maintaining cardiovascular health and puts forward new ideas to provide references for gene therapy or nanoagents targeting Piezo1. | Junyang Huang Kun Zhang Ruolin Du Wanling Liu Haijun Zhang Tian Tian Yazhou Wang Guixue Wang Tieying Yin | 2023 | Genes & Diseases2023，10，5： | 1 |
| 13 | Object tracking and detecting based on adaptive background subtraction显示文摘 | ZHANG Ruolin DING Jian | 2012 | Procedia Engineering2012，29，1： | 1 |
| 14 | The First Verification Test of Space-Ground Collaborative Intelligence via Cloud-Native Satellites显示文摘Recent advancements in satellite technologies and the declining cost of access to space have led to the emergence of large satellite constellations in Low Earth Orbit(LEO).However,these constellations often rely on bent-pipe architecture,resulting in high communication costs.Existing onboard inference architectures suffer from limitations in terms of low accuracy and inflexibility in the deployment and management of in-orbit applications.To address these challenges,we propose a cloud-native-based satellite design specifically tailored for Earth Observation tasks,enabling diverse computing paradigms.In this work,we present a case study of a satellite-ground collaborative inference system deployed in the Tiansuan constellation,demonstrating a remarkable 50%accuracy improvement and a substantial 90%data reduction.Our work sheds light on in-orbit energy,where in-orbit computing accounts for 17%of the total onboard energy consumption.Our approach represents a significant advancement of cloud-native satellite,aiming to enhance the accuracy of in-orbit computing while simultaneously reducing communication cost. | Wang Shangguang Zhang Qiyang Xing Ruolin Qi Fei Xu Mengwei | 2024 | China Communications2024，21，4： | 0 |
| 15 | Genome-wide CRISPR screening reveals key genes and pathways associated with 20-hydroxyecdysone signal transduction in the silkworm(Bombyx mori)显示文摘Metamorphosis is a complex developmental process involving multiple pathways and a large number of genes that are regulated by juvenile hormone(JH)and 20-hydroxyecdysone(20E).Despite important progress in understanding various aspects of silkworm biology,the hormone signaling pathway in the silkworm remains poorly understood.Genome-wide screening using clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)-based libraries has recently emerged as a novel method for analyzing genome function,enabling further research into essential genes,drug targets,and virus-host interaction.Previously,we constructed a genome-wide CRISPR/Cas9-based library of the silkworm(Bombyx mori)and successfully revealed the genes involved in biotic or abiotic stress factor responses.In this study,we used our silkworm CRISPR library and large-scale genome-wide screening to analyze the key genes in the silkworm 20E signaling pathway and their mechanisms of action.Functional annotation showed that 20E regulates key proteins in processes that mainly occur in the cytoplasm and nucleus.Pathway enrichment analysis showed that 20E can activate phosphorylation and may affect innate immunity,interfere with intracellular nutrition and energy metabolism,and eventually cause cell apoptosis.The screening results were experimentally validated by generating cells with knockout alleles of the relevant genes,which had increased tolerance to 20E.Our findings provide a panoramic overview of signaling in response to 20E in the silkworm,underscoring the utility of genome-wide CRISPR mutant libraries in deciphering hormone signaling pathways and the mechanisms that regulate metamorphosis in insects. | Hao Sun Jingya Chen Ruolin Wang Dan Liu Na Zhang Tong Zhang Ling Jia Sanyuan Ma Qingyou Xia | 2024 | Insect Science2024，31，1： | 0 |
| 16 | Middle or low water pressure direct spiral double helix converging nozzle structure optimization and flow field analysis显示文摘In order to solve the problem of using middle or low water pressure to form fine water mist,a new nozzle is proposed in fire rescue robot.Existing water mist nozzles are basically used for high pressure and in large size,complex structure and poor low pressure atomization effect in comparison with requirement of snake-like fire rescue robots.On the basis of comprehensive typical spray nozzles,a direct spiral double helix converging nozzle(DSDHCN) is proposed,which has the advantages of small volume,light weight,simple structure,and convenient installation.To make the spray nozzle have good performance,and meet the requirements of more efficient fire extinguishing,a numerical study is carried out to analyze the internal and external full flow field of nozzle.A gas-liquid two-phase flow is applied to simulate the external full flow field of nozzle with VOF model in fluent software.The simulation results show the real situation of water flow out of the atomization nozzle and the water jet trajectory.Some simulations about middle or low water pressure direct spiral double helix converging optimized nozzle have been done in 30 bar pressure.The simulation results show that the optimized nozzle structure not only makes the spray droplets have a good cone angle,but also have a sufficient axial velocity,which proves the structure rationality of the proposed optimized nozzle. | 蒋林 Wu Ruolin Zhao Hui Mei Peng Zhang Qiang Zhu Jiangyang Xiao Jun Lei Bin | 2015 | High Technology Letters2015，21，3： | 0 |
| 17 | Genetic architecture of quantitative trait loci(QTL)for FHB resistance and agronomic traits in a hard winter wheat population显示文摘Wheat resistance to Fusarium head blight(FHB)has often been associated with some undesirable agronomic traits.To study the relationship between wheat FHB resistance and agronomic traits,we constructed a linkage map of single nucleotide polymorphisms(SNPs)using an F6:8 population from G97252WG97380A.The two hard winter wheat parents showed contrasts in FHB resistance,plant height(HT),heading date(HD),spike length(SL),spike compactness(SC),kernel number per spike(KNS),spikelet number per spike(SNS),thousand-grain weight(TGW)and grain size(length and width).Quantitative trait locus(QTL)mapping identified one major QTL(QFhb.hwwg-2DS)on chromosome arm 2DS for the percentage of symptomatic spikelets(PSS)in the spike,deoxynivalenol(DON)content and Fusarium damaged kernel(FDK).This QTL explained up to 71.8%of the phenotypic variation for the three FHB-related traits and overlapped with the major QTL for HT,HD,SL,KNS,SNS,TGW,and grain size.QTL on chromosome arms 2AL,2DS,3AL and 4BS were significant for the spike and grain traits measured.G97252W contributed FHB resistance and high SNS alleles at QFhb.hwwg-2DS,high KNS alleles at the QTL on 2AL and 2DS,and high TGW and grain size alleles at QTL on 3AL;whereas G97380A contributed high TGW and grain size alleles at the QTL on 2AL and 2DS,respectively,and the high KNS allele at the 4BS QTL.Combining QFhb.hwwg-2DS with positive alleles for spike and grain traits from other chromosomes may simultaneously improve FHB resistance and grain yield in new cultivars. | Yuzhou Xu Yaoguang Li Ruolin Bian Guorong Zhang Allan K.Fritz Yanhong Dong Lanfei Zhao Yunfeng Xu Nida Ghori Amy Bernardo Paul StAmand Jessica L.Shoup Rupp Myron Bruce Wei Wang Eduard Akhunov Brett Carver Guihua Bai | 2023 | The Crop Journal2023，11，6： | 0 |
| 18 | The impact of water quality on the formation of halogenated benzoquinones and the adsorption efficiency by activated carbon显示文摘Halogenated benzoquinones(HBQs)could cause bladder cancer,but there were few related studies on the generation and control.In this study,the impact of different precursors,pH,bromide concentration,and algae-derived organic matters on the formation of HBQs and the removal efficiency by activated carbon were investigated.It was found that the chlorination of bisphenol A produced the most 2,6-dichloro-1,4-benzoquinone(2,6-DCBQ),reaching 14.86μg/L at 1 hr,followed by tyrosine,2-chlorophenol,P-hydroxybenzoic acid,trichlorophenol,and N-methylaniline.The production of 2,6-DCBQ increased first and then decreased from 0 to 36 hr(chlorination doses 0-20 mg/L),indicating that HBQs were unstable in water.Trihalomethanes(THMs)were detected during chlorination,and the concentration increased with prolongation of reaction time.2,6-DCBQ production decreased and 2,6-dibromo-1,4-benzoquinone(2,6-DBBQ)production increased with increment bromide concentration and the bromide promoted the formation of tribromomethane.The production of 2,6-DCBQ decreased with increase of pH,and the maximum production was 141.38μg/L at pH of 5.Microcystis aeruginosa,Chlorella algae cells,and intracellular organic matters(IOM)could be chlorinated as potential precursors for HBQs.The most amount of 2,6-DCBQ was generated from algae cells of Microcystis aeruginosa,followed by Chlorella algae cells,Microcystis aeruginosa IOM,and Chlorella IOM.This study compared the removal efficiency of HBQs by granular activated carbon(GAC)and columnar activated carbon(CAC)under different carbon doses and initial concentrations of HBQs.It was found that the removal efficiency by GAC(80.1%)was higher than that by CAC(51.8%),indicating that GAC has better control for HBQs. | Yongjing Wang Song Gao Xinyu Yan Songtao Wang Ruolin Zhang Yan Zhou Lianhai Ren Cheng Li | 2024 | Journal of Environmental Sciences2024，，1： | 0 |
| 19 | Occurrence and Health Risk of Perfluoroalkyl Acids in Popular Shellfish from a Typical Coastal Area of the East China显示文摘As crucial homologous members of per-and polyfluoroalkyl substances(PFASs),perfluoroalkyl acids(PFAAs)have aroused wide public concern because of their unique properties(persistence,bioaccumulation,long-distance migration and toxicity).Studies have shown their potential hazard to wildlife and humans,with food consumption as one of the primary routes of PFAA exposure for general population,especially seafood intake.In this study,17 PFAAs were quantified in 9 shellfish species from Yuhuan City,a typical coastal area of the East China.The total mean concentrations of PFAAs were in the range of 5.03–381 ng/g dry weight(dw),with the highest concentration found in Neverita didyma and the lowest in Babylonia lutosa.Concentrations and composition profiles of PFAAs varied significantly among different species,indicating differences in the bioaccumulation potential of PFAAs among species.Perfluorooctanoic acid(PFOA)was presented as the most abundant PFAA in this study,followed by perfluorobutanoic acid(PFBA).Significant positive correlations were observed among some individual PFAAs(p<0.05),indicating that they may share similar pollution sources or undergo similar compound behaviors.Health risk assessment indicated a relatively high threat for local residents exposed to PFAAs through shellfish consumption. | LIU Ruolin LIU Mei ZHAO Chuxuan FU Jianjie ZHOU Wei ZHANG Qinghua Martin HANSEN DONG Yin | 2023 | Chemical Research in Chinese Universities2023，39，3： | 0 |
| 20 | Efficient Contact between H_(2)O and N-Coordinate Ru Nanoparticles in Three-Dimensionally Ordered Macro/Mesoporous Carbon Boosting Alkaline HER显示文摘In this study,a novel approach is proposed to achieve the uniformly dispersed Ru nanoparticles with N coordination loaded on three-dimensionally ordered macro/mesoporous carbon(3DOMMC)through simultaneous pyrolysis of Ru^(3+)and cyanamide on 33DOMMC.In an alkaline medium,the synthesized catalysts exhibit exceptional hydrogen evolution reaction(HER)performance.Specificall,Ru-N/3DOMMC demonstrates a significantly low overpotential of 13.8 mV to achieve acrent density of 10 mA.cmzandit exhibits a mass activity 17.5 times higher than that of commercial Pt/C.The outstanding performance could be attributed to the ultrahigh Ru dispersion and more efficient contact between active sites and reactant,which derived from the large specific surface area and interconnective three-dimensionally macro/mesopores of 3DOMMC. | Jiaqing Luo Chunyu Liu Ruolin Zhang Yuanqing Sun Hua Xu Qingying Hu Manxue Zhang Jun Li Zhenxing Li Weiyu Song Yuechang Wei Jian Liu | 2024 | Chinese Journal of Chemistry2024，42，2： | 0 |
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