|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 3 | Finite element modeling of the three-dimensional ground deformations due to tunnelling in son cohesive soils: pant Ⅰ -method of analysis显示文摘 | Lee K M Rowe R K | 1990 | Con'' puters and Geotechnics1990，，10： | 2 |
| 4 | A Theoretical Examination of the Settlements Induced by tunneling; Four Case Histories显示文摘 | Rowe R K and Kack G J | 1983 | Canadian Geotechnical Journal1983，，20： | 2 |
| 5 | Oxidative environments decrease tenderization of beef steaks through inactivation of μ-ealpain显示文摘 | Rowe L J Maddock K P Lonergan S M | 2004 | J Anita Sci2004，82，： | 1 |
| 6 | Subsidence owing to unnelling (Ⅱ): Evaluztionof a prediction technique显示文摘 | Rowe R K Lo K Y | 1992 | Canadian Geotechnical Journal1992，29，： | 1 |
| 7 | Determination of Enrofloxacin and Ciprofloxacin in Milk Using Molecularly Imprinted Solid - phase Extraction显示文摘 | Yan H Y Tian M L Row K H | 2008 | J Sep Sci2008，31，： | 1 |
| 8 | Selected factors influencing GCL hydraulic conductivity显示文摘 | PETROV R J ROWE R K QUIGLEY R M | 1997 | Journal Geotechnical and Geoenvironmental Engineering1997，123，8： | 1 |
| 9 | Analysis of the three-dimensional ground movements,the Thunder Bay Tunnel显示文摘 | Lee K M Rowe R K | 1991 | Canadian Geotechnical Journal1991，，1： | 1 |
| 10 | Field Observations of Clog-ging in a Landfill Leachate Collection System显示文摘 | Fleming I R Rowe R K Cullimore D R | 1999 | Can Geotech J1999，36，4： | 1 |
| 11 | An evaluation of simplified techniques for estimating three-dimensional undrained ground movements due to tunneling in soft soils显示文摘 | ROWE R K LEE K M | 1992 | Canadian Geotechnical Journal1992，29，： | 1 |
| 12 | Finite dement modeling of the three di- mensional ground deformations due to tunneling in soft cohesive soil:part I- method of analysis显示文摘 | LEE K M ROWE R K | 1990 | Computers and Geotechnics1990，2，2： | 1 |
| 13 | Field observations of clogging in a landfill leachate collection system显示文摘 | FLEMIN I R ROWE R K CULLIMORE D R | 1999 | Canadian Geotechnical Journal1999，36，4： | 1 |
| 14 | Rainfall Interception by an Evergreen Beech Forest,Nelson,New Zealand显示文摘 | ROWE L K | 1983 | Journal of Hydrology1983，66，： | 1 |
| 15 | Favorable results with syringosubanachnoid shunts for treatment of syringomyelia显示文摘 | Tator C H Meguro K Rowed D W | 1982 | J Neurosurg1982，56，4： | 1 |
| 16 | Testing the safety-net role of hedgerow tree roots by 15N placement different soil depths显示文摘 | Rowe E C Hairaih K Giner K E | 1999 | Agroforestry System1999，43，： | 1 |
| 17 | Molecularly Imprinted Monolithic Material forthe Extraction of Three Organic Acids from Salicornia herbacea L显示文摘 | ZHU T LI S N ROW K H | 2011 | Journal of Applied Polymer Science2011，121，： | 1 |
| 18 | Influence of landfill leachate suspended solids on clog (biorock) formation显示文摘 | VanGulck J F Rowe R K | | 0，，： | 1 |
| 19 | Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle显示文摘 | Shimp RL Jr Rowe C Reiter K | | 0，，28： | 1 |
| 20 | Favorable results with syringosubaraehnoid shunt for treatment of syringomyelia显示文摘 | Tator CH Meguro K Rowed DW | 1982 | J Neurosurgery1982，56，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员