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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Optimal linear image combination显示文摘 | Rowe B Hirata C Rhodes J | 2011 | The Astronomical Journal2011，74，： | 1 |
| 3 | Production of in vitro matured oocytes from 6-week old calves显示文摘 | Earl C R Irvine B J Rowe J P | | 0，，： | 1 |
| 4 | Viscosity-Elastic Analysis of Hot Mix Asphalt Pavement显示文摘 | Rowe B Sharrock S F Bouldin M J | 1995 | Transportation Research Record1995，，1482： | 1 |
| 5 | Avoidance of Thermal Damage in Grinding and Prediction of the Damage Threshold显示文摘 | ROWE W B PETTIT J A BOYLE | 1988 | Annals of the CIRP1988，37，1： | 1 |
| 6 | Estimation of the Convection Heat Transfer Coefficient of Cool- ant within the Grinding gone显示文摘 | Jin T Stephenson D J Rowe W B | 2003 | Journal of Engi neering Manufacture2003，217，3： | 1 |
| 7 | Avoidance ofThermal Damage in Grinding and Prediction of theDamage Threshold显示文摘 | ROWE W B PETTIT J A BOYLE A | 1988 | Annals of the CIRP1988，37，1： | 1 |
| 8 | Mix Rheology-a Tool for Predicting the High Temperature Performance of Hot Mix Asphalt显示文摘 | Bouldin G M Rowe J B Sousa M J Sharrock | 1994 | Journal of the Association Asphalt Paving Technologists1994，63，： | 1 |
| 9 | Collagen biomechanics in cerebral arteries and bifurcations assessed by polarizing microscopy显示文摘 | Rowe A J Finlay H M Canham P B | 2003 | J Vasc Res2003，40，4： | 1 |
| 10 | Effect of PEGylation on the solution conformation of antibody fragments显示文摘 | Lu Y Harding S E Turner A Smith B Athwal D S Grossmann J G Davis K G Rowe A J | 2008 | Journal of Pharmaceutical Sciences2008，97，6： | 1 |
| 11 | Gene expression of instdin-like growth factors I and Ⅱ in rat membranous osteotomy healing显示文摘 | Steinbreeh DS Mehram B J Rowe NM | 1999 | Ann Plnst Surg1999，42，5： | 1 |
| 12 | Modulation of prostacyclin and thromboxane by cytotrophoblast from normal and pre - eclampsia human pregnancies 显示文摘 | Ding ZQ Rowe J Nj B | 2002 | Placenta2002，23，89： | 1 |
| 13 | Crystal Dynamics of Copper 显示文摘 | Svensson E C Broekhouse B N Rowe J M | 1967 | Phys Rev1967，155，： | 1 |
| 14 | Effect of supplemental trace-mineral source on bull semen quality显示文摘 | Rowe M P Powell J G Kegley E B Lester T D Rorie R W | 2014 | Professional Animal Scientist2014，，1： | 1 |
| 15 | Prevention and treatment of acute graft-versus-host-disease: the old and the new显示文摘 | Lazarus H M Vogelsang G B Rowe J M | 1997 | Bone Marrow Transplant1997，19，： | 1 |
| 16 | Biofilm growth and mineral precipitation in synthetic leachate columns显示文摘 | COOKE A J ROWE R K RITTMANN B E | 2001 | Journal of Geotechnical and Geoenvironmental Engineering2001，127，10： | 1 |
| 17 | Green roof stormwater retention:Effects of roof surface, slope and media depth显示文摘 | Vanwoert N D Rowe D B Andresen J A | 2005 | Journal of Environmental Quallity2005，34，3： | 1 |
| 18 | Volatile organic compounds in ground water from rural private wells, 1986 to 1999显示文摘 | Moran M J Lapham W W Rowe B L | 2004 | Journal of the American Water Resources Associa- tion2004，40，5： | 1 |
| 19 | Impaired spatial learning and hyperactivity in developing rats exposed to intermittent hypoxia显示文摘 | Row B W Kheirandish L Neville J J | 2002 | Pediatr Res2002，52，3： | 1 |
| 20 | Green roofs stormwater retention: effects of roof surface, slope and media depth 显示文摘 | van Woert N D Rowe D B Andresenm J A | 2005 | Journal of Environmental Quality2005，34，3： | 1 |
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