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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Evaluating public participation exercises : a research agenda 显示文摘 | Rowe G Frewer L J | 2004 | Science Technology & Human Values2004，29，4： | 1 |
| 3 | Characterization of an animal model of continuous peritoneal dialysis in chronic renal impairment显示文摘 | Miller T Findon G Rowe L | 1992 | Clin Nephrol1992，37，： | 1 |
| 4 | Host status of agriculturally important plant families to the root-knot nematode Meloidogyne mayaguensis in Cuba 显示文摘 | Rodriguez M G Sanchez L Rowe J | 2004 | Nematropica2004，33，2： | 1 |
| 5 | Air-water exchange of polychlorinated biphenyls in the Delaware River 显示文摘 | Rowe A Totten L Xie M G | 2004 | Environ Sci Technol2004，41，4： | 1 |
| 6 | NCR-42 Committee on Swine Nutrition 显示文摘 | CROMWELL G L CLINE T R CRENSHAW J D The dietary protein and (or) lysine requirements of bar- rows and gilts | 1993 | Journal of Animal Science1993，71，6： | 1 |
| 7 | Complex transcriptional control links NikABCDE-dependent nickel transport with hydrogenase expression in Escherichia coli显示文摘 | Rowe J L Starnes G L Chivers PT | 2005 | Journal of Bacteriology2005，187，7： | 1 |
| 8 | Biological export of shelf carbon as a neglected sink of the global CO2 cycles显示文摘 | WALSH J J ROW G T IVERSON R L | 1981 | Nat1981，291，： | 1 |
| 9 | Crossover interference in the mouse显示文摘 | Rowe L B Churchill G A Paigen K | 2002 | Genetics2002，160，3： | 1 |
| 10 | Identifying potentialenvironmental impacts of large-scale deployment ofdedicated bioenergy crops in the UK显示文摘 | Rowe R L Street N R Taylor G | 2009 | Renewable &Sustainable Energy Reviews2009，13，： | 1 |
| 11 | Isolation of cucurbitacin C from Cucumis prophetarum Linn 显示文摘 | Ran M G Row L R | 1986 | Curr Sci1986，13，： | 1 |
| 12 | Public Participation Methods: A Framework for Evaluation 显示文摘 | ROWE G FREWER L J | 2000 | Science Technology & Human Values2000，25，1： | 1 |
| 13 | Use of ^3H/^3He ages to evaluate and improve groundwater flow models in a complete buried-valley aquifer 显示文摘 | Sheets R A Bair E S Rowe G L | 1998 | Water Resources Research1998，34，： | 1 |
| 14 | Persistence genetic stability of Ebola virus during the outbreak in Kikwit,Democratic Republic of the Congo,1995显示文摘 | Rodriguez L L De Roo A Guimard Y Trappier S G Sanchez A Bressler D Williams A J Rowe A K Bertolli J Khan A S Ksiazek T G Peters C J and Nichol S T | 1999 | J Infect Dis1999，1791，： | 1 |
| 15 | Public Participation Methods: A Framework for Evaluation显示文摘 | Rowe G Prewer L J | 2000 | Science Technology & Human Values2000，25，1： | 1 |
| 16 | Do radiographie indices of distal radius fracture reduction predict outcomes in older adults receiving conservative treatment 显示文摘 | Jaremko J L Lambert R G Rowe B H | 2007 | Clin Radi- ol2007，62，1： | 1 |
| 17 | Megafaunal biomass in the deep sea显示文摘 | Haedrich R L Rowe G T | 1977 | Nature1977，269，5624： | 1 |
| 18 | Characterization of an animal model of continuous peritoneal dialysis in chronic renal impaiment显示文摘 | Miller TE Findon G Rowe L | 1992 | Clin Nephrol1992，37，： | 1 |
| 19 | Immune responses during pregnancy in heifers naturally infected with Neospora caninum with and without immunization显示文摘 | Andrianarivo A G Anderson M L Rowe J D | 2005 | Parasi tol Res2005，96，1： | 1 |
| 20 | Do radiograph- ic indices of distal radius fracture reduction predict outcomes in ol- der adults receiving conservative treatment 显示文摘 | JAREMKO J L LAMBERT R G ROWE B H | 2007 | Clin Radio12007，62，1： | 1 |
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