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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes : results of a 6-month, randomized, comparative trial 显示文摘 | Hollander PA Blonde L Rowe R | 2004 | Diabetes Care2004，27，10： | 1 |
| 3 | A soluble form of Epstein-Barr virus gH/gL inhibits EBV-induced membrane fusion and does not function in fusion显示文摘 | Rowe C L Connolly S A Chen J Jardetzky T S Longnecker R | 2013 | Virology2013，436，1： | 1 |
| 4 | Extraction and HPLC Analysis of Halofuginone in Chicken Serum显示文摘 | Beier R C Rowe L D Abd El-Aziz Nasr M I | 1994 | J Liquid Chromatogr1994，17，13： | 1 |
| 5 | Facile Synthesis of Carboxylic Linker on Halofuginone:A Method to Derivatize Haptens Containing both Amine and Hydroxy Functionalities显示文摘 | Rowe L D Beier R C Elissalde M H | 1993 | Synthetic Conmunications1993，23，15： | 1 |
| 6 | Production and Characterization of Monoclonal Antibodies Against the Poultry Coccidiostat Halofuginone显示文摘 | Rowe L D Beier R C Elissalde M H | 1994 | J Agric Food Chem1994，42，： | 1 |
| 7 | Detection of Halofuginone Residues in Chicken Serum by a Monoclonal-based Immunoassay and High-perfomance Liquid Chromatography显示文摘 | Beier R C Rowe L D Abd El-Aziz Nasr M I | 1996 | Food & Agricultural Immunology1996，8，： | 1 |
| 8 | NCR-42 Committee on Swine Nutrition 显示文摘 | CROMWELL G L CLINE T R CRENSHAW J D The dietary protein and (or) lysine requirements of bar- rows and gilts | 1993 | Journal of Animal Science1993，71，6： | 1 |
| 9 | Isolation and characterization of bergenin derivaves from Macaranga peltata显示文摘 | Ramaiah P A Row L R Reddy D S | 1979 | JCSPerkin 11979，，9： | 1 |
| 10 | Differentiated cultures of primary hamster tracheal airway epithelial cells显示文摘 | Rowe R K Brody S L | | 0，，10： | 1 |
| 11 | Efficacy and safety of inhaled insulin(Exubera)compared with subcutaneous insulin therapy in patients with type 2 diabetes:results of a6month,randomized,comparative trial显示文摘 | Hollander PA Blonde L Rowe R | 2004 | Diabetes Care2004，27，10： | 1 |
| 12 | Biological export of shelf carbon as a neglected sink of the global CO2 cycles显示文摘 | WALSH J J ROW G T IVERSON R L | 1981 | Nat1981，291，： | 1 |
| 13 | The unsatisfactory thin- Prep pap test missed opportunity for disease detection? 显示文摘 | Bentz J S Rowe L R Gopez E V | 2002 | Am J Clin Patho12002，117，3： | 1 |
| 14 | Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia显示文摘 | DiNardo C D Propert K J Loren A W Paietta E Sun Z X Levine R L Straley K S Yen K Patel J P Agresta S Abdel-Wahab O Perl A E Litzow M R Rowe J M Lazarus H M Fernandez H F Margolis D J Tallman M S Luger S M Carroll M | 2012 | Blood2012，121，24： | 1 |
| 15 | Isolation of a cy topathic agent from human adenoids undergoing spontaneous degradation in tissue culture显示文摘 | Rowe W P H uebner R J Gilmore L K et a l | 1953 | Proceedings of the Society for Experimental Biology and Medicine1953，84，： | 1 |
| 16 | Efficacy and safety of inhaled insulin (exubera)compared with subcutaneous insulin therapy in patients with type 2 diabetes: results of a 6 month, randomized, comparative trial 显示文摘 | Hollander PA Blonde L Rowe R | 2004 | Diabetes Care2004，27，10： | 1 |
| 17 | Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes:results of a 6-month,randomized,comparative trial显示文摘 | HOLLANDER P A BLONDE L ROWE R | 2004 | Diabetes Care2004，27，10： | 1 |
| 18 | A distinct lineage of influenza A virus from bats显示文摘 | Tong S Li Y Rivailler P Conrardy C Castillo D A Chen L M Recuenco S Ellison J A Davis C T York I A Turmelle A S Moran D Rogers S Shi M Tao Y Weil M R Tang K Rowe L A Sammons S Xu X Frace M Lindblade K A Cox N J Anderson L J Rupprecht C E Donis R O | 2012 | PANS2012，109，11： | 1 |
| 19 | Stabilization of very soft soils using high strength geosynthetics:the role of finite element analyses显示文摘 | ROWE R K SODERMAN K L | 1987 | Geotextiles and Geomembranes1987，6，13： | 1 |
| 20 | Influence of the emetic reflex on vasopressin-release in man显示文摘 | ROWE J W SHELTON R L HELDERMAN J H | 1979 | Kidney International1979，16，： | 1 |
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