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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Oxidative environments decrease tenderization of beef steaks through inactivation of μ-ealpain显示文摘 | Rowe L J Maddock K P Lonergan S M | 2004 | J Anita Sci2004，82，： | 1 |
| 3 | A prospective,randomized,placebo controlled,double-blind study of pelvic electromagnetic therapy for the treatment of chronic pelvic pain syndrome with 1 year of followup显示文摘 | Rowe E Smith C Laverick L | 2005 | J Urol2005，173，6： | 1 |
| 4 | Determination of Enrofloxacin and Ciprofloxacin in Milk Using Molecularly Imprinted Solid - phase Extraction显示文摘 | Yan H Y Tian M L Row K H | 2008 | J Sep Sci2008，31，： | 1 |
| 5 | Comparison of video shot boundary detection techniques 显示文摘 | Boreczky J S Rowe L A | 1996 | Journal of Elec- tronic Imaging1996，5，2： | 1 |
| 6 | Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase Ⅱ显示文摘 | Tewey KM Rowe TC Yang L | 1984 | Science1984，226，4673： | 1 |
| 7 | Effects of sibutramine on body weight and serum lipids: a double-blind, randomized, placebo-controlled study in 322 overweight and obese patients with dyslipidemia显示文摘 | Dujovne CA Zavoral JH Rowe E eta l | 2001 | Am Heart J2001，142，3： | 1 |
| 8 | The effects of increasing lev- els of soluble non-starch polysaccharides and inclusion of feed enzymes in dog diets on faecal quality and digestibility显示文摘 | TWOMEY L PLUSKE J ROWE J | 2003 | An Feed Sei Teehnol2003，108，14： | 1 |
| 9 | Evidence-based treatments for acute asthma显示文摘 | ROWE B H EDMONDS M L SPOONER C H | 2001 | Respir Care2001，46，12： | 1 |
| 10 | Timeline AIDS pathogenesis what have two decades of HIV research taught us显示文摘 | Row land-Jones S L | 2003 | Nat Rev Immunol2003，3，4： | 1 |
| 11 | Effects of dietary sodium bicarbonate and calcium chloride on physiological responses of lactating dairy cows in hot weather显示文摘 | ESCOBASA A COPPOCK C E ROWE L D | 1984 | Dairy Sci1984，67，： | 1 |
| 12 | Evaluating public participation exercises : a research agenda 显示文摘 | Rowe G Frewer L J | 2004 | Science Technology & Human Values2004，29，4： | 1 |
| 13 | Com- parative analysis of superintegrons: engineering extensive genetic diversity in the Vibrionaceae 显示文摘 | Rowe Magnus DA Guerout AM Biskri L etal | 2003 | Genome Res2003，13，3： | 1 |
| 14 | Rainfall Interception by an Evergreen Beech Forest,Nelson,New Zealand显示文摘 | ROWE L K | 1983 | Journal of Hydrology1983，66，： | 1 |
| 15 | Neuroprotection by pramipexole against dopamine- and levodopa- induced cytotoxicity 显示文摘 | Jankovic J Rowe DB | 1999 | Life Sci1999，64，15： | 1 |
| 16 | Systematic review of noninvasive positive pressuer ventilation in severe stable COPD显示文摘 | Kolodziej MA Jensen L Rowe B | 2007 | Eur Respir J2007，30，2： | 1 |
| 17 | The use of stereotactic radiosurgery in the management of meningiomas显示文摘 | Malik I Rowe JG Walton L | 2005 | Br J Neurosurg2005，19，1： | 1 |
| 18 | Increased oxidative stress is associated with chronic intermittent hypoxia-mediated brain cortical neuronal cell apoptosis in a mouse model of sleep apnea显示文摘 | Xu W Chi L Row BW | 2004 | Neuroscience2004，126，2： | 1 |
| 19 | Apolipoprotein E-deficient mice exhibit increased vulnerability to inter- mittent hypoxia-induced spatial learning deficits显示文摘 | Kheirandish L Row BW Li RC | 2005 | Sleep2005，28，11： | 1 |
| 20 | Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes : results of a 6-month, randomized, comparative trial 显示文摘 | Hollander PA Blonde L Rowe R | 2004 | Diabetes Care2004，27，10： | 1 |
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