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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Results of Charleston Bracing in skeletally immature patients with idiopathic scoliosis显示文摘 | Rowe DE | 2002 | J Pediatr Orthop2002，22，4： | 1 |
| 3 | Long-term recurrence rates inpre-viously untreated(primary)basal cell carcinoma:Implications forpa-tient follow-up显示文摘 | Rowe DE Carroll RJ Day CL JR | 1989 | Dermatol Surg Oncol1989，15，4： | 1 |
| 4 | Prognostic factors for local recur-rence,metastases,and several rates in SCC of skin,ear,and lip显示文摘 | Rowe DE Carroll RJ Day CL | 1991 | Am Acad Dermatol1991，26，5： | 1 |
| 5 | A metaanalysis of the efficacy of non-operative treatments for idiopathic scoliosis显示文摘 | Bemstein SM Riddick MF | 1997 | J Bone Joint Surg1997，，： | 1 |
| 6 | Acute changes in circulating natriu retic peptide level in relation to myocardial ischemia 显示文摘 | Sabatine MS M or row DA de Lemos JA | 2004 | J Am Coil Cardiol2004，44，： | 1 |
| 7 | MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia 显示文摘 | Rowe PS de Zoysa PA Dong R | 2000 | Genomies2000，67，1： | 1 |
| 8 | Complications associated withharvesting autogenous iliac bone graft显示文摘 | Fowler BL Dall BE Rowe DE | 1995 | Am J Orthop1995，24，12： | 1 |
| 9 | A meta-analysis of the efficacy of non -operative treatments for idiopathic scoliosis显示文摘 | Rowe DE Bernstein SM Riddick MF | 1997 | J Bone Joint Surg (Am)1997，79，5： | 1 |
| 10 | Long term recurrence rates in previously untreated (primary) basal cell carcinoma显示文摘 | Rowe DE Carroll RJ Day CL Jr | 1989 | J Dermatol Surg Oncol1989，15，： | 1 |
| 11 | MEPE,a new gene expressed in bone marrow and tumors causing osteomalacia显示文摘 | Rowe PS de Zoysa PA Dong R | 2000 | Genomics2000，67，1： | 1 |
| 12 | Phylogenetic relationships within the cyst-forming nematodes (Nem toda:Heteroderidae) based on analysis of sequences from the ITS regions of ribosomal DNA显示文摘 | SUBBOTIN S A VIERSTRAETE A DE LEY P ROWE J WAEYENBERGE L MOENS M & VANFLETEREN J R | | 0，，： | 1 |
| 13 | Long-term recurrence rates in previously untreated (primary)basal cell carcinoma: implications for patient follow-ap显示文摘 | Carroll RJ Day CL | 1989 | J Dermatol Surg Oncol1989，15，3： | 1 |
| 14 | MEPE,a new gene expressed in bone marrow and tumors causing osteomalacia显示文摘 | Rowe PS de Zoysa PA Dong R | 2000 | Genomics2000，67，1： | 1 |
| 15 | A meta-anal- ysis of the efficacy of non-operative treatment for idio- pathic scoliosis显示文摘 | Rowe DE Bernstein SM Riddick MF | 1997 | J Bone Joint Surg Am1997，79，5： | 1 |
| 16 | Ohstructive sleep apo- nea syndrome due to adenotonsillar hypeophy in infants显示文摘 | Greenfeld M Tauman R De Rowe A | 2003 | Int J Pediatr Otorhinolaryngol2003，67，10： | 1 |
| 17 | MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia 显示文摘 | Rowe PS de Zoysa PA Dong R | 2000 | Genomics2000，67，1： | 1 |
| 18 | A meta-analysis of the efficacy of non -operative treatments for idiopathic scoliosis显示文摘 | Rowe DE Bernstein SM Riddick MF | 1997 | J Bone Joint Surg Am1997，79，5： | 1 |
| 19 | MEPE,a new gene expressed in bone marrow and tumors causing osteomalacia显示文摘 | Rowe PS De Zoysa PA Dong R | | 0，，01： | 1 |
| 20 | Persistence genetic stability of Ebola virus during the outbreak in Kikwit,Democratic Republic of the Congo,1995显示文摘 | Rodriguez L L De Roo A Guimard Y Trappier S G Sanchez A Bressler D Williams A J Rowe A K Bertolli J Khan A S Ksiazek T G Peters C J and Nichol S T | 1999 | J Infect Dis1999，1791，： | 1 |
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