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| 1 | High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate. | Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo | 2013 | World Journal of Gastroenterology2013，19，20： | 23 |
| 2 | Lobar Hepatocellular Carcinoma with Ipsilateral Portal Vein Tumor Thrombosis Treated with Yttrium-90 Glass Microsphere Radioembolization: Preliminary Results显示文摘 | M. Pracht J. Edeline L. Lenoir M. Latournerie H. Mesbah O. Audrain Y. Rolland B. Clément J. L. Raoul E. Garin E. Boucher Zhi Dai | 2013 | International Journal of Hepatology2013，，： | 1 |
| 3 | Revisiting the ABCs of multi- drug resistance in cancer ehemotherapy显示文摘 | Tiwari AK Sodani K Dai CL | 2011 | Curr Pharrn Biotechnol2011，12，4： | 1 |
| 4 | Heat shock protein 72 production in liver tissue after experimental total hepatic inflow occlusion 显示文摘 | 19,DAI CL Kume M Yamamoto Y | 1998 | Br J Surg1998，85，8： | 1 |
| 5 | Heat-shock protein 72 production in liver tissue after experimental total hepatic inflow occlusion显示文摘 | Dai CL Kume M Yamamoto Y | | 0，，08： | 1 |
| 6 | Type I collagen receptor α2β1 signaling promotes the growth of human prostate cancer cells within the bone显示文摘 | Hall CL Dai JL van Golen KL | 2006 | Cancer Res2006，66，： | 1 |
| 7 | Chronic cerebral hypoperfusion causes decrease of o-glcnacylation, hyperphosphorylation of tau and behav- ioral deficits in mice显示文摘 | Zhao Y Gu JH Dai CL | 2014 | Front Aging Neurosci2014，6，10： | 1 |
| 8 | Elevated muscle en- zymes and muscle biopsy in idiopathic hypoparathyroidism patients 显示文摘 | Dai CL Sun ZJ Zhang X | 2012 | J Endocrinol Invest2012，35，： | 1 |
| 9 | Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2显示文摘 | Dai CL Liang YJ Wang YS | 2009 | Cancer Lett2009，279，： | 1 |
| 10 | Intravitreal triameinolone aeetonide for radiation maculopathy after plaque radiotherapy for choroidal melanoma显示文摘 | Shields CL Demirci H Dai V | 2005 | Retina2005，25，7： | 1 |
| 11 | Prostate cancer induces bone metastasis through Wnt-indueed bone morphogenetic protein-dependent and independent mechanisms显示文摘 | Dai J Hall CL Escara-Wilke J | 2008 | Cancer Res2008，68，14： | 1 |
| 12 | Degradable, antibacterial silver exchanged mesoporous silica spheres for hemor- rhage control显示文摘 | Dai CL Yuan Y Liu CS | 2009 | Biomaterials2009，30，29： | 1 |
| 13 | Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms 显示文摘 | Dai J Hall CL Escara-Wilke J | 2008 | Cancer Res2008，68，14： | 1 |
| 14 | Undifferentiated Embryonal Sarcoma of the Liver: a Case Re- port 显示文摘 | Dai CL Xu F | 2005 | World J Gastroenterol2005，11，6： | 1 |
| 15 | Attenuation of reperfusion-induced hepato- cyte apoptosis is associated with reversed Bcl-2/Bax ratio in hemihepatic artery-preserved portal occlusion显示文摘 | Jin S Dai CL | 2012 | J Surg Res2012，174，2： | 1 |
| 16 | Lymphoma of bone with initial presentation as a calvarial mass显示文摘 | Dai MS Ho CL Chen CY | 2000 | Ann Hematol2000，79，： | 1 |
| 17 | Risk factor for postoperative complication after hepaticresection inpatients with the hepatocellular carcinoma 显示文摘 | Dai CL Huai MS Zhu X | 2001 | J Jpn Surg Assoc2001，，： | 1 |
| 18 | Lapatinib (tykerb, GW572016) reverses muhidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2 显示文摘 | Dai CL Tiwari AK Wu CP Su XD Wang SR Liu DG | 2008 | 68 (19): 7905- 79142008，68，19： | 1 |
| 19 | Revisiting the ABGs of multi-drug resistance in cancer chemotherapy显示文摘 | Tiwari AK Sodani K Dai CL | 2011 | Curr Pharm Biotechn-ol2011，12，4： | 1 |
| 20 | High serum microRNA-122 level is independently associated with higher overall survival rate in hepatoceUular carcinoma patients显示文摘 | Xu YQ Bu XM Dai CL | 2015 | Tumor Biology2015，36，6： | 1 |
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