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| 1 | Immunogenetic phenotypes in inflammatory bowel disease显示文摘当前接受的 etiopathogenic 假设建议长期的肠的发炎和煽动性的肠疾病(IBD ) 的相关全身的表明特征由于对居民钠的过分好攻击或病理学的有免疫力的回答细菌的成分。预先安排的因素是粘膜免疫者回答或障碍功能的基因 dysregulation,与环境刺激触发的发作。这些因素和他们的相互作用可以也是疾病显型和疾病前进的重要决定因素。免疫的出现基因显型把支持借给不同免疫者处理的危险性基因调整的建议假设,由钠抗原开车,表示了接着在 IBD 影响临床的显型的同样特定的有免疫力的显型病人。 | Maria C Dubinsky Kent Taylor Stephan R Targan Jerome I Rotter | 2006 | World Journal of Gastroenterology2006，12，23： | 4 |
| 2 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 3 | Neutrophil autoantibodies in ulcerative colitis familial aggregation and genetic heterogeneity 显示文摘 | Shanahan F Duerr R H Rotter J I | 1992 | Gastroenterology1992，103，2： | 1 |
| 4 | Clinical pathways : effects on professional practice, patient outcomes, length of stay and hospital costs显示文摘 | Rotter T Koch R Kugler J | 2007 | Cochrane Database Syst Rev2007，17，3： | 1 |
| 5 | Renin expression in renal ablation显示文摘 | Correa· Rotter R Hostetter TH Manivel JC | 1992 | Hypertension1992，20，4： | 1 |
| 6 | Compression tests on cylinders with circumferential weld depressions显示文摘 | Berry P A Rotter J M Bridge R Q | 2000 | Journal of Engineering Mechanics ASCE2000，126，4： | 1 |
| 7 | Additional freeze hardiness in wheat acquired by exposure to -- 3 C is associated with extensive physiological, morphological, and molecular changes 显示文摘 | Herman E M Rotter K Premakumar R | 2006 | Journal of Experimental Botany2006，57，： | 1 |
| 8 | Effect of dietary protein on renin and angiotensinogen gene expression after renal ablation显示文摘 | Correa· Rotter R Hostetter TH Rosenberg ME | 1992 | Am y Physiol1992，262，： | 1 |
| 9 | Chondroblastoma of the patella associated with an aneurysmal bone cyst显示文摘 | Trebse R Rotter A Pisot V | 2001 | Acta Orthop Belg2001，67，3： | 1 |
| 10 | Clinical pathways:effects on professional practice,patient outcomes,length of stay and hospital costs显示文摘 | Rotter T Koch R Kugler J | 2007 | Cochrane Database Syst Rev2007，3，： | 1 |
| 11 | Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention显示文摘 | Gansevoort RT Correa - Rotter R Hemmelgarn BR | 2013 | Lancet2013，382，9889： | 1 |
| 12 | Ischemic preconditioning prevents skeletal muscle tissue injury, but not nerve lesion upon tourniquetinduced ischemia 显示文摘 | Schoen M Rotter R Gierer P | 2007 | J Trauma2007，63，4： | 1 |
| 13 | Application of time-based fractional calculus methods to viscoelastic creep and stress relaxation of materials 显示文摘 | Welch S W J Rotter R A L Duren R G | 1999 | Mechanics of Time-Dependent Materials1999，3，3： | 1 |
| 14 | Imperfections and buckling in cylindrical shells with consistent residual stresses 显示文摘 | Mark J Hoist F G Rotter J Michael Calladine Chris R | 2000 | Journal of Constructional Steel Research2000，54，： | 1 |
| 15 | Introduction of a new interlocked intramedullary nailing device for stabi- lization of critically sized femoral defects in the rat: A combined biomechanical and animal experimental study 显示文摘 | Schoen M Rotter R Schattner S | 2008 | J Orthop Res2008，26，2： | 1 |
| 16 | A systematic review and meta - anal- ysis of the effects of clinical pathways on length of stay,hospital costs and patient outcomes显示文摘 | Rotter T Kugler J Koch R | 2008 | BMC Health Serv Res2008，8，： | 1 |
| 17 | In vitro viscosity measuments of barley extracts as predictors of growth re- sponses in chicks fed barley-based diets supplemented with a fungal enzyme preparation 显示文摘 | Rotter B A Marquardt R R Guenter W | 1989 | Can J Anita Sci1989，69，： | 1 |
| 18 | Technique for precise measurement of large-scale silos and tanks显示文摘 | DING X COLEMAN R ROTTER J M | 1995 | Journal of Surveying Engineering ASCE1995，122，1： | 1 |
| 19 | Granulocyte-eolony stimulating factor enhances muscle proliferation and strength following skeletal muscle injury in rats 显示文摘 | Stratos I Rotter R Eipel C | 2007 | J Appl Physiol2007，103，5： | 1 |
| 20 | A systematic review and metaanalysis of the effects of clinical pathway soil length of stay,hospi-tal costs and patient outcomes显示文摘 | Rotter T Kugler J Koch R | 2008 | BMC Health Serv Res2008，19，8： | 1 |
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