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| 1 | Solitary fibrous tumors in abdomen and pelvis:Imaging characteristics and radiologic-pathologic correlation显示文摘AIM:To describe the imaging features of solitary fibrous tumors(SFTs)in the abdomen and pelvis,and the clinical and pathologic correlations.METHODS:Fifteen patients with pathologically confirmed SFTs in the abdomen and pelvis were retrospectively studied with imaging techniques by two radiologists in consensus.Patients underwent unenhanced and contrast-enhanced imaging,as follows:3 with computed tomography(CT)and magnetic resonance imaging(MRI)examination,8 with CT examination only,and 4 with MRI examination only.Image characteristics such as size,shape,margin,attenuation or intensity,and pattern of enhancement were analyzed and correlated with the microscopic findings identified from surgical specimens.In addition,patient demographics,presentation,and outcomes were recorded.RESULTS:Of the 15 patients evaluated,local symptoms related to the mass were found in 11 cases at admission.The size of the mass ranged from 3.4 to 25.1cm(mean,11.5 cm).Nine cases were round or oval,6were lobulated,and 10 displaced adjacent organs.Unenhanced CT revealed a heterogeneous isodense mass in 7 cases,homogeneous isodense mass in 3 cases,and punctuated calcification in one case.On MRI,most of the lesions(6/7)were heterogeneous isointense and heterogeneous hyperintense on T1-weighted images and T2-weighted images,respectively.All tumors showed moderate to marked enhancement.Heterogeneous enhancement was revealed in 11 lesions,and 7of these had cysts,necrosis,or hemorrhage.Early nonuniform enhancement with a radial area that proved to be a fibrous component was observed in 4 lesions,which showed progressive enhancement in the venous and delayed phase.No statistical difference in the imaging findings was observed between the histologically benign and malignant lesions.Three patients had local recurrence or metastasis at follow-up.CONCLUSION:Abdominal and pelvic SFTs commonly appeared as large,solid,well-defined,hypervascular masses with variable degrees of necrosis or cystic change that often displaced adjacent structures. | Xue-Ming Li Jing Reng Peng Zhou Ying Cao Zhu-Zhong Cheng Yan Xiao Guo-Hui Xu | 2014 | World Journal of Gastroenterology2014，20，17： | 27 |
| 2 | Analysis of PRLR and BF Genotypes Associated with Litter Size in Beijing Black Pig Population显示文摘This study is aimed at using the DNA mutations in the prolactin receptor (PRLR) and properdin (BF) genes to determine associations between the genotype and litter size in the Beijing Black pig population. A total of 321 Beijing Black pig sows were genotyped using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method,with the Alu I and Sma I for PRLR and BF genes,respectively. Two different alleles of PRLR and BF genes were identified:allele A (0.25) and B (0.75) of the PRLR gene,allele A (0.13) and B (0.86) of the BF gene. The association analysis between the genotypes and the litter size were estimated with the method of the general linear model. The analysis results of PRLR showed that in first parity,sows with genotype AA had a larger litter size than sows with genotype AB and BB,but the difference was statistically not significant. In later parities,statistically significant (P < 0.05) differences were seen between sows with genotypes AA and AB,and BB of the PRLR gene. The associated analysis results between genotypes and litter size (total number born,TNB,and number born alive,NBA) showed that there were no significant differences in the first parity sows with different genotypes of the BF gene,but significant differences appeared in NBA between the sows of genotypes AB and BB,in later parity,for which significantly higher values were observed in the offspring of heterozygotes. Considering the consistent genotypic effect on the litter size of both sows in first parity and later parity,it was concluded that the locus of the PRLR gene,digested with Alu I,could be the gene maker for the litter size in Beijing Black pigs. | WANG Xing-ping WANG Li-xian LUO RENG Zhuo-ma SUN Shi-duo | 2008 | Agricultural Sciences in China2008，7，11： | 5 |
| 3 | Outcomes of percutaneous coronary intervention in patients ≥ 75 years: one-center study in a Chinese patient group显示文摘ObjectiveTo 调查临床并且病人 ≥ 的 perioperative 特征;75 经历经皮的冠的干预(一种总线标准) 并且从 2011 年 12 月经历了一种总线标准到 2013 年 11 月的连续题目被划分在这特定的病人 group.Methods1,035 评估与短期的一种总线标准以后的死亡有关的风险因素成四个范畴:(1 ) 有稳定的咽峡炎(SA ) 的病人 ≥75 年(n = 58 ) ;(2 ) 有 SA < 的病人;75 年(n = 218 ) ;(3 ) 有急性冠的症候群(交流) 的病人 ≥75 年(n = 155 ) ;(4 ) 有交流 < 的病人;75 年(n = 604 ) 。multivariable 逻辑回归分析被进行在病人 ≥ 检测六月的死亡的风险因素;75 年经历了一种总线标准。临床的 comorbidities,在里面医院生物化学的指示物, perioperative 数据,在里面医院和六月的结果与更年轻的组,一起在四 groups.ResultsCompared 之中被分析并且比较病人 ≥75 年是更可能的有高血压,中风的历史,长期的妨碍的肺的疾病,外部脉管的疾病,心脏性的吃惊和恶意的心律不齐,并且他们与相对更低的重量,血红素,白朊, triglyceride,更高的 creatinine,尿酸,脲氮和 pro-BNP 进入医院。左主要动脉损害,多容器,钙化的损害,长期完全吸藏也是更可能的在老组被看。Univariate 分析揭示了那年龄 ≥在承认,紧急情况一种总线标准,优先的击和长期的肾疾病的 85 年,心脏性的吃惊或严重心律不齐与在老病人 ≥ 的六月的死亡有关;75 年经历了一种总线标准。Multivariable 逻辑回归证明在承认,长期的肾疾病和优先的击的心脏性的吃惊或严重心律不齐是在老病人 ≥ 预言六月的死亡的独立风险因素;75 年经历了 PCI.ConclusionsOur 数据的人,显示出那与在 75 年下面的病人相比,老病人(≥75 年) 经历了一种总线标准的人,有经常伴有 multi-comorbidities, severer 承认条件和复杂冠的损害的死亡,和更多的相对更高的风险。因素和更多强烈地在乎的风险的更好的评估应该被带去病人 ≥75 年经历了一种总线标准治疗减少复杂并发症。 | Peng-Fei CHEN Dan-Ning WANG Kan CHEN Chun LIANG Yu-Sheng RENG Jing YANG Ru DING Jacob Blackwell De-Ning LIAO | 2015 | Journal of Geriatric Cardiology2015，12，6： | 4 |
| 4 | Materials Experiment on Tiangong-2 Space Laboratory显示文摘During the China's Tiangong-2(TG-2) flight mission, the experiments of 18 kinds of material samples were conducted in space by using a Multiple Materials Processing Furnace(MMPF) mounted in the orbital module of the TG-2 space laboratory. After the experiments of 12 kinds of samples of the first and second batches were completed successfully, astronauts packed and brought them back to the ground by ShenzhouII spacecraft. By studying processing and formation on semiconductor and optoelectronics materials, metal alloys and metastable materials, functional single-crystal, micro-and nano-composite materials encapsulated in sample ampoules both in space and on Earth, we expect to explore some physical and chemical processes and mechanism of the materials formation that are normally obscured and therefore are difficult to study quantitatively on the ground due to the gravity-induced convection, to obtain the processing and synthesis technology for preparing high quality materials, and lead to the improvement and development of materials processing techniques on Earth, and also develop the experiment device and comprehensive ability for materials experiment in microgravity environment. This report briefly introduces the main points of each research work and preliminary comparative analysis results of 12 samples carried out by scientists undertaking research task. | LI Xiangyang LU Ye MENG Xiangjian WANG Jianlu WANG Reng CHEN Lidong HUA Zile LI Xiaoya SHI Jianlin LIU Jinfeng XU Guisheng WEI Bingbo XIE Wenjun YIN Zhigang ZHANG Xingwang JIANG Hongxiang LI Hong LUO Xinghong ZHANG Haifeng ZHAO Jiuzhou WANG Binbin PAN Mingxiang | 2018 | 空间科学学报2018，38，5： | 4 |
| 5 | Aberrant DNA methyltransferase 1 expression in clear cell renal cell carcinoma development and progression显示文摘Objective: To better understand the contribution of dysregulated DNA methyltransferase 1(DNMT1) expression to the progression and biology of clear cell renal cell carcinoma(ccRCC).Methods: We examined the differences in the expression of DNMT1 in 89 ccRCC and 22 normal tissue samples by immunohistochemistry. In addition, changes in cell viability, apoptosis, colony formation and invading ability of ccRCC cell lines(786-0 and Caki-1) were assessed after transfection with DNMT1 siRNA.Results: We found DNMT1 protein was significantly higher expressed in ccRCC than that of in no-tumor tissues(56.2% and 27.3%, respectively, P=0.018). The expression of DNMT1 was strongly associated with ccRCC tumor size, tumor pathology stage, histological grading, lymph node metastasis, vascular invasion, recurrence and prognosis. Moreover, knockdown of DNMT1 expression significantly inhibited ccRCC cell viability, induced apoptosis, decreased colony formation and invading ability.Conclusions: Expression of DNMT1 protein is increased in ccRCC tissues, and DNMT1 expression is associated with poor prognosis of patients. Experiments in vitro further showed DNMT1 played an essential role in proliferation and invasion of renal cancer cells. Moreover, targeting this enzyme could be a promising strategy for treating ccRCC, as evidenced by inhibited cell viability, increased apoptosis, decreased colony formation and invading ability. | Ming Li Ying Wang Yongsheng Song Renge Bu Bo Yin Xiang Fei Qizhen Guo Bin Wu | 2014 | Chinese Journal of Cancer Research2014，26，4： | 3 |
| 6 | Significance of scintigraphy for the localisation of obscure gastrointestinal bleedings显示文摘AIM: To determine the role of scintigraphy in patients with gastrointestinal (GI) bleeding of unknown localisation. METHODS: We performed retrospective analyses on 92 patients receiving scintigraphies from 1993 to 2000 in the University of Regensburg hospital, which were done for localisation of GI bleeding as a diagnostic step after an unsuccessful endoscopy. In addition to the scintigraphies, further diagnostic steps such as endoscopy, angiography or operations were performed. In some of the scintigraphies with negative results, a provocation test for bleeding with heparinisation was carried out. RESULTS: 73% of all scintigraphies showed a positive result. In 4.5% of the positive results, the source was located in the stomach, in 37% the source was the small bowel, in 25% the source was the right colon, in 4.5% the source was the left colon, and in 20% no clear localisation was possible. Only 4% of all scintigraphies were false positive. A reliablepositive scintigraphy was independent of the age of the examined patient. A provocation test for bleeding with heparin resulted in an additional 46% of positive scintigraphies with a reliable localisation in primary negative scintigraphies. CONCLUSION: Our results show that scintigraphy and scintigraphy with heparin provocation tests are reliable procedures. They enable a reliable localisation in about half of the obscure GI-bleeding cases. Scintigraphy is superior to angiography in locating a bleeding. It is shown that even in the age of video capsule endoscopy and double-balloon enteroscopy, scintigraphy provides a reliable and directed localization of GI bleeding and offers carefully targeted guidance for other procedures. | Tanja Brünnler Frank Klebl Sascha Mundorff Christoph Eilles Michael Reng Hans von Korn Jürgen Schlmerich Julia Langgartner Stefan Grüne | 2008 | World Journal of Gastroenterology2008，14，32： | 3 |
| 7 | Proteome analysis of human mesenchymal stem cells undergoing chondrogenesis when exposed to the products of various magnesium-based materials degradation显示文摘Treatment of physeal fractures(15%–30%of all paediatric fractures)remains a challenge as in approximately 10%of the cases,significant growth disturbance may occur.Bioresorbable Magnesium-based implants represent a strategy to minimize damage(i.e.,load support until bone healing without second surgery).Nevertheless,the absence of harmful effects of magnesium-implants and their degradation products on the growth plate should be confirmed.Here,the proteome of human mesenchymal stem cells undergoing chondrogenesis was evaluated when exposed to the products of various Magnesium-based materials degradation.The results of this study indicate that the materials induced regulation of proteins associated with cell chondrogenesis and cartilage formation,which should be beneficial for cartilage regeneration. | Adela Helvia Martínez Sánchez Maryam Omidi Marcus Wurlitzer Marceline Manka Fuh Frank Feyerabend Hartmut Schlüter Regine Willumeit-Römer Bérengère J.C.Luthringer | 2019 | Bioactive Materials2019，4，1： | 2 |
| 8 | Haptic rendering for dental training system显示文摘Immersion and interaction are two key features of virtual reality systems, which are especially impor- tant for medical applications. Based on the requirement of motor skill training in dental surgery, haptic rendering method based on triangle model is investigated in this paper. Multi-rate haptic rendering architecture is proposed to solve the contradiction between fidelity and efficiency requirements. Real- time collision detection algorithm based on spatial partition and time coherence is utilized to enable fast contact determination. Proxy-based collision response algorithm is proposed to compute surface contact point. Cutting force model based on piecewise contact transition model is proposed for dental drilling simulation during tooth preparation. Velocity-driven levels of detail haptic rendering algorithm is proposed to maintain high update rate for complex scenes with a large number of triangles. Haptic- visual collocated dental training prototype is established using half-mirror solution. Typical dental op- erations have been realized including dental caries exploration, detection of boundary within dental cross-section plane, and dental drilling during tooth preparation. The haptic rendering method is a fun- damental technology to improve immersion and interaction of virtual reality training systems, which is useful not only in dental training, but also in other surgical training systems. | WANG DangXiao ZHANG YuRu WANG Yong LU PeiJun ZHOU RenGe ZHOU WanLin | 2009 | Science in China(Series F)2009，52，3： | 2 |
| 9 | Apolipop-rotein B Gene Polymorphisms are Associated with Lipid Levels in Men of South Asian Descent显示文摘 | RENGES H H WILE D B MCKEIGUE P M | 1991 | Atherosclerosis1991，91，3： | 1 |
| 10 | Pumpless extracorporeal lung assist-experience with the first 20 cases 显示文摘 | Liebold A Reng CM Philipp A | 2000 | Eur J Cardiothorac surg2000，17，： | 1 |
| 11 | Thalidomide in systemic mastocytosis: results from an open‐label, multicentre, phase II study显示文摘 | Bérengère Gruson Olivier Lortholary Danielle Canioni Olivia Chandesris Fanny Lanternier Julie Bruneau Bernard Grosbois Cristina Livideanu Claire Larroche Isabelle Durieu Stéphane Barete Henri Sevestre Momar Diouf Guillaume Chaby Jean‐Pierre Marolleau Patr | 2013 | Br J Haematol2013，，3： | 1 |
| 12 | Pumpless extracoporeal lung assist and adult resporatory didtress syndrome 显示文摘 | Reng M Philipp A Kaiser M | 2000 | Lancet2000，356，9225： | 1 |
| 13 | The treatment of irre-sectable liver tumors by percutaneous targeted Ar-He cryoablation显示文摘 | Wang SM Zhang JR Reng QP | 2000 | Int J Modern Cancer Ther2000，3，： | 1 |
| 14 | Analysis of a centered-inclinedwaveguide slot coupler显示文摘 | RENG ARAJ AN S R | 1989 | IEEE Microwave Theoryand Techniques Society1989，37，5： | 1 |
| 15 | Long-term follow-up of allogeneic stem cell transplantation in patients with severe aplastic anemia after conditioning with cyclophosphamide plus antithymocyte globulin显示文摘 | N. Kr?ger T. Zabelina H. Renges W. Krüger U. Kordes J. Rischewski J. Schrum M. Horstmann F. Ayuk R. Erttmann H. Kabisch A. Zander | 2002 | Annals of Hematology2002，，11： | 1 |
| 16 | A combined basdstepping and small-gain approach to robust adaptive fuzzy control for strict-feedback nonlinear systems 显示文摘 | Yang Y S Feng G Reng J S | 2004 | IEEE Transactions on Systems Man and Cybernetics-part A~ System and Hmuan2004，34，3： | 1 |
| 17 | Chlorine reaction with sea-water constituents and inhibition of photosynthesis of natural marine phytoplankton显示文摘 | Eppley R W Renges E H Williams P M | | 0，，02： | 1 |
| 18 | Drivers' Hazard and Risk Perception,Confi- dence in Safe Driving,and Choice of Speed显示文摘 | Renge K | 1998 | IATSS research1998，，2： | 1 |
| 19 | Breed difference and regulation of the porcine adipose triglyceride lipase and hormone sensi tire lipase by TNFa 显示文摘 | Shan T Wu T Reng Y | 2009 | Anita Genet2009，40，6： | 1 |
| 20 | A new SNR’s estimator for QPSKmodulations in an AWGN channel 显示文摘 | Reng Chang Yl Zhang H | 2005 | IEEE Trans on circuits andsystems (SI549-7747)2005，52，6： | 1 |
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