|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Analysis of PRLR and BF Genotypes Associated with Litter Size in Beijing Black Pig Population显示文摘This study is aimed at using the DNA mutations in the prolactin receptor (PRLR) and properdin (BF) genes to determine associations between the genotype and litter size in the Beijing Black pig population. A total of 321 Beijing Black pig sows were genotyped using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method,with the Alu I and Sma I for PRLR and BF genes,respectively. Two different alleles of PRLR and BF genes were identified:allele A (0.25) and B (0.75) of the PRLR gene,allele A (0.13) and B (0.86) of the BF gene. The association analysis between the genotypes and the litter size were estimated with the method of the general linear model. The analysis results of PRLR showed that in first parity,sows with genotype AA had a larger litter size than sows with genotype AB and BB,but the difference was statistically not significant. In later parities,statistically significant (P < 0.05) differences were seen between sows with genotypes AA and AB,and BB of the PRLR gene. The associated analysis results between genotypes and litter size (total number born,TNB,and number born alive,NBA) showed that there were no significant differences in the first parity sows with different genotypes of the BF gene,but significant differences appeared in NBA between the sows of genotypes AB and BB,in later parity,for which significantly higher values were observed in the offspring of heterozygotes. Considering the consistent genotypic effect on the litter size of both sows in first parity and later parity,it was concluded that the locus of the PRLR gene,digested with Alu I,could be the gene maker for the litter size in Beijing Black pigs. | WANG Xing-ping WANG Li-xian LUO RENG Zhuo-ma SUN Shi-duo | 2008 | Agricultural Sciences in China2008，7，11： | 5 |
| 2 | Outcomes of percutaneous coronary intervention in patients ≥ 75 years: one-center study in a Chinese patient group显示文摘ObjectiveTo 调查临床并且病人 ≥ 的 perioperative 特征;75 经历经皮的冠的干预(一种总线标准) 并且从 2011 年 12 月经历了一种总线标准到 2013 年 11 月的连续题目被划分在这特定的病人 group.Methods1,035 评估与短期的一种总线标准以后的死亡有关的风险因素成四个范畴:(1 ) 有稳定的咽峡炎(SA ) 的病人 ≥75 年(n = 58 ) ;(2 ) 有 SA < 的病人;75 年(n = 218 ) ;(3 ) 有急性冠的症候群(交流) 的病人 ≥75 年(n = 155 ) ;(4 ) 有交流 < 的病人;75 年(n = 604 ) 。multivariable 逻辑回归分析被进行在病人 ≥ 检测六月的死亡的风险因素;75 年经历了一种总线标准。临床的 comorbidities,在里面医院生物化学的指示物, perioperative 数据,在里面医院和六月的结果与更年轻的组,一起在四 groups.ResultsCompared 之中被分析并且比较病人 ≥75 年是更可能的有高血压,中风的历史,长期的妨碍的肺的疾病,外部脉管的疾病,心脏性的吃惊和恶意的心律不齐,并且他们与相对更低的重量,血红素,白朊, triglyceride,更高的 creatinine,尿酸,脲氮和 pro-BNP 进入医院。左主要动脉损害,多容器,钙化的损害,长期完全吸藏也是更可能的在老组被看。Univariate 分析揭示了那年龄 ≥在承认,紧急情况一种总线标准,优先的击和长期的肾疾病的 85 年,心脏性的吃惊或严重心律不齐与在老病人 ≥ 的六月的死亡有关;75 年经历了一种总线标准。Multivariable 逻辑回归证明在承认,长期的肾疾病和优先的击的心脏性的吃惊或严重心律不齐是在老病人 ≥ 预言六月的死亡的独立风险因素;75 年经历了 PCI.ConclusionsOur 数据的人,显示出那与在 75 年下面的病人相比,老病人(≥75 年) 经历了一种总线标准的人,有经常伴有 multi-comorbidities, severer 承认条件和复杂冠的损害的死亡,和更多的相对更高的风险。因素和更多强烈地在乎的风险的更好的评估应该被带去病人 ≥75 年经历了一种总线标准治疗减少复杂并发症。 | Peng-Fei CHEN Dan-Ning WANG Kan CHEN Chun LIANG Yu-Sheng RENG Jing YANG Ru DING Jacob Blackwell De-Ning LIAO | 2015 | Journal of Geriatric Cardiology2015，12，6： | 4 |
| 3 | Materials Experiment on Tiangong-2 Space Laboratory显示文摘During the China's Tiangong-2(TG-2) flight mission, the experiments of 18 kinds of material samples were conducted in space by using a Multiple Materials Processing Furnace(MMPF) mounted in the orbital module of the TG-2 space laboratory. After the experiments of 12 kinds of samples of the first and second batches were completed successfully, astronauts packed and brought them back to the ground by ShenzhouII spacecraft. By studying processing and formation on semiconductor and optoelectronics materials, metal alloys and metastable materials, functional single-crystal, micro-and nano-composite materials encapsulated in sample ampoules both in space and on Earth, we expect to explore some physical and chemical processes and mechanism of the materials formation that are normally obscured and therefore are difficult to study quantitatively on the ground due to the gravity-induced convection, to obtain the processing and synthesis technology for preparing high quality materials, and lead to the improvement and development of materials processing techniques on Earth, and also develop the experiment device and comprehensive ability for materials experiment in microgravity environment. This report briefly introduces the main points of each research work and preliminary comparative analysis results of 12 samples carried out by scientists undertaking research task. | LI Xiangyang LU Ye MENG Xiangjian WANG Jianlu WANG Reng CHEN Lidong HUA Zile LI Xiaoya SHI Jianlin LIU Jinfeng XU Guisheng WEI Bingbo XIE Wenjun YIN Zhigang ZHANG Xingwang JIANG Hongxiang LI Hong LUO Xinghong ZHANG Haifeng ZHAO Jiuzhou WANG Binbin PAN Mingxiang | 2018 | 空间科学学报2018，38，5： | 4 |
| 4 | Aberrant DNA methyltransferase 1 expression in clear cell renal cell carcinoma development and progression显示文摘Objective: To better understand the contribution of dysregulated DNA methyltransferase 1(DNMT1) expression to the progression and biology of clear cell renal cell carcinoma(ccRCC).Methods: We examined the differences in the expression of DNMT1 in 89 ccRCC and 22 normal tissue samples by immunohistochemistry. In addition, changes in cell viability, apoptosis, colony formation and invading ability of ccRCC cell lines(786-0 and Caki-1) were assessed after transfection with DNMT1 siRNA.Results: We found DNMT1 protein was significantly higher expressed in ccRCC than that of in no-tumor tissues(56.2% and 27.3%, respectively, P=0.018). The expression of DNMT1 was strongly associated with ccRCC tumor size, tumor pathology stage, histological grading, lymph node metastasis, vascular invasion, recurrence and prognosis. Moreover, knockdown of DNMT1 expression significantly inhibited ccRCC cell viability, induced apoptosis, decreased colony formation and invading ability.Conclusions: Expression of DNMT1 protein is increased in ccRCC tissues, and DNMT1 expression is associated with poor prognosis of patients. Experiments in vitro further showed DNMT1 played an essential role in proliferation and invasion of renal cancer cells. Moreover, targeting this enzyme could be a promising strategy for treating ccRCC, as evidenced by inhibited cell viability, increased apoptosis, decreased colony formation and invading ability. | Ming Li Ying Wang Yongsheng Song Renge Bu Bo Yin Xiang Fei Qizhen Guo Bin Wu | 2014 | Chinese Journal of Cancer Research2014，26，4： | 3 |
| 5 | Haptic rendering for dental training system显示文摘Immersion and interaction are two key features of virtual reality systems, which are especially impor- tant for medical applications. Based on the requirement of motor skill training in dental surgery, haptic rendering method based on triangle model is investigated in this paper. Multi-rate haptic rendering architecture is proposed to solve the contradiction between fidelity and efficiency requirements. Real- time collision detection algorithm based on spatial partition and time coherence is utilized to enable fast contact determination. Proxy-based collision response algorithm is proposed to compute surface contact point. Cutting force model based on piecewise contact transition model is proposed for dental drilling simulation during tooth preparation. Velocity-driven levels of detail haptic rendering algorithm is proposed to maintain high update rate for complex scenes with a large number of triangles. Haptic- visual collocated dental training prototype is established using half-mirror solution. Typical dental op- erations have been realized including dental caries exploration, detection of boundary within dental cross-section plane, and dental drilling during tooth preparation. The haptic rendering method is a fun- damental technology to improve immersion and interaction of virtual reality training systems, which is useful not only in dental training, but also in other surgical training systems. | WANG DangXiao ZHANG YuRu WANG Yong LU PeiJun ZHOU RenGe ZHOU WanLin | 2009 | Science in China(Series F)2009，52，3： | 2 |
| 6 | The treatment of irre-sectable liver tumors by percutaneous targeted Ar-He cryoablation显示文摘 | Wang SM Zhang JR Reng QP | 2000 | Int J Modern Cancer Ther2000，3，： | 1 |
| 7 | Overexpression of Y-box binding protein-1 in cervical, cancer and its association with the pathological response rate to chemoradiotherapy显示文摘 | Zhang Y Reng SR Wang L | 2012 | Med Oncol2012，29，3： | 1 |
| 8 | Overexpression of Y-box binding protein-1in cervical cancer and its association with the pathological response rate to chemoradiotherapy显示文摘 | Zhang Y Reng SR Wang L | 2012 | Med Oncol2012，29，3： | 1 |
| 9 | The treatment of irresectable liver tumors by percutaneous targeted Ar-He cryoablation显示文摘 | Senming Wang Jiren Zhang Qiuping Reng | 2000 | Int J Modern Cancer Ther2000，3，： | 1 |
| 10 | The treatment of irresectable live tumors by percutaneous targeted Ar-He cryoablation显示文摘 | Wang SM Zhang JR Reng QP | 2000 | Int J Mod Cancer Ther2000，3，： | 1 |
| 11 | Overexpression of Y-box binding protein-1 in cervical cancer and its association with the pathological response rate to chemoradiotherapy 显示文摘 | Zhang Y Reng SR Wang L | 2012 | Med Oncol2012，29，3： | 1 |
| 12 | Different gene expression of mice radiation injury repair in small intestine RNA 显示文摘 | Zeng GY Wang F Qian FR Yan XJ Reng DT Zhao T Su CZ | 2000 | Di-si Junyi Daxue Xuebao (J Fourth Mil Med Univ)2000，21，2： | 1 |
| 13 | The treatment of irresectable live tumors by percutaneous targeted Ar-He cryoablation显示文摘 | Wang S M Zhang J R Reng Q P | 2000 | International Journal of Modern Cancer Therapy2000，3，： | 1 |
| 14 | The treatment ofirresectable liver tumors by percutaneous targeted Ar-Hecryoablation显示文摘 | Wang SM Zhang JR Reng QP | 2000 | Int J Modern Cancer Ther2000，3，： | 1 |
| 15 | The treatment of irresectable liver tumors bypercutaneous targeted Ar-He cryoablation显示文摘 | Senming Wang Jiren Zhang Qiuping Reng etal | 2000 | Int J Modern Cancer Ther2000，3，： | 1 |
| 16 | Overexpression of Y-box binding protein-1 in cervical cancer and its association with the pathological response rate to chemoradiatherapy显示文摘 | Zhang Y Reng SR Wang L | | 0，，： | 1 |
| 17 | The treatment of irresectable liver tumors by percutaneous targeted Ar-He cryoablation显示文摘 | Zhang JR Reng QP | 2000 | Int J Modern Cancer Ther2000，3，1： | 1 |
| 18 | Overexpression of Y-box binding protein-1 in cervical cancer and its association with the pathological response rate to chemoradiotherapy 显示文摘 | ZHANG Y RENG S R WANG L | 2012 | Med 0ncol2012，29，3： | 1 |
| 19 | Overexpression of Y-box binding protein-1in cervical cancer and its association with the pathological response rate to chemoradiatherapy显示文摘 | Zhang Y Reng S R Wang L | 2012 | Med Oncol2012，29，3： | 1 |
| 20 | The treatment of irresectable Live Tumors by percutaneous targeted Ar-He Cryoablation显示文摘 | Zhang JR Reng QP | 2000 | International Journal of Modern Cancer Therapy2000，3，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员