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1Neutrophil extracellular trap cell death requires both autophagy and superoxide generation显示文摘嗜中性的细胞外的陷井(网) 是能套住并且降级的细胞外的染色质结构微生物。他们从激活称为网络房间死亡,或 NETosis 的一个房间死亡程序的 neutrophils 产生。NETosis 的激活被显示了包含 NADPH oxidase 活动,原子信封的崩溃和大多数小粒膜,网的原子染色质和形成的 decondensation。我们报导在 phorbol,十四酸盐醋酸盐(PMA ) 刺激了 neutrophils,细胞内部的染色质 decondensation 和网形成跟随 autophagy 和 superoxide 生产,哪个被要求调停导致 PMA 的 NETosis 并且独立于对方发生。从有长期的 granulomatous 疾病的病人的 Neutrophils,缺乏 NADPH oxidase 活动,仍然展出导致 PMA 的 autophagy。相反地,导致 PMA 的 NADPH oxidase 活动没被 autophagy 的药理学抑制影响。有趣地,任何一个 autophagy 的抑制或 NADPH oxidase 阻止细胞内部的染色质 decondensation,它为 NETosis 和网形成是必要的,并且导致 apoptosis 的特点描绘的房间死亡。当 autophagy 或 NADPH oxidase 活动被阻止时,这些结果显示 apoptosis 可能为 NETosis 作为一个备份节目工作。Quinten Remij sen Tom Vanden Berghe Ellen Wirawan Bob Asselbergh Eef Parthoens Riet De Rycke Sam Noppen Michel Delforge Jean Wlllems Peter Vandenabeele 2011Cell Research2011,21,2:46
2Homing and migration of mesenchymal stromal cells: How to improve the efficacy of cell therapy?显示文摘Mesenchymal stromal cells(MSCs) are currently being investigated for use in a wide variety of clinical applications. For most of these applications, systemic delivery of the cells is preferred. However, this requires the homing and migration of MSCs to a target tissue. Although MSC hominghas been described, this process does not appear to be highly efficacious because only a few cells reach the target tissue and remain there after systemic administration. This has been ascribed to low expression levels of homing molecules, the loss of expression of such molecules during expansion, and the heterogeneity of MSCs in cultures and MSC culture protocols. To overcome these limitations, different methods to improve the homing capacity of MSCs have been examined. Here, we review the current understanding of MSC homing, with a particular focus on homing to bone marrow. In addition, we summarize the strategies that have been developed to improve this process. A better understanding of MSC biology, MSC migration and homing mechanisms will allow us to prepare MSCs with optimal homing capacities. The efficacy of therapeutic applications is dependent on efficient delivery of the cells and can, therefore, only benefit from better insights into the homing mechanisms.Ann De Becker Ivan Van Riet 2016World Journal of Stem Cells2016,8,3:37
3SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress显示文摘Hyun-Seok Kim Krish Patel Kristi Muldoon-Jacobs Kheem S. Bisht Nukhet Aykin-Burns J. Daniel Pennington Riet van der Meer Phuongmai Nguyen Jason Savage Kjerstin M. Owens Athanassios Vassilopoulos Ozkan Ozden Seong-Hoon Park Keshav K. Singh Sarki A. Abdulka 2010Cancer Cell2010,,1:3
4Effect of the HDAC inhibitor vorinostat on the osteogenic differentiation of mesenchymal stem cells in vitro and bone formation in vivo显示文摘Song XU Kim DE VEIRMAN Holly EVANS Gaia Cecilia SANTINI: Isabelle VANDE BROEKI XavierLELEU Ann DEBECKER Ben VAN CAMP Peter CROUCHER Karin VANDERKERKEN Ivan VAN RIET 2013Acta Pharmacologica Sinica2013,34,5:3
5Prognostic value of bone sialoprotein expression in clinically localized hu- man prostate cancer显示文摘Waltregny D Bellahcene A Van Riet I 1998J Natl Cancer Inst1998,90,13:1
6Detrimental ef- fects of overstttffing or understuffing with a radial head replacement in the medial collateral-ligament deficient elbow 显示文摘Van Glahbeek F Van Riet RP Baumfeld JA 2004J Bone Joint Surg ( Am )2004,86,12:1
7Comprehensive geriatric assessment, multifactorial interventions and nurse - led care coordination to prevent functional decline in community - dwelling older persons : protocol of a cluster randomized trial 显示文摘Suijker JJ Buurman BM ter Riet G 2012BMC Health Serv Res2012,,12:1
8营养对母猪跛足和蹄部健康的影响显示文摘造成母猪跛足的原因是多方面的,主要与骨重建、软骨代谢和角质产生等过程发生紊乱有关。本文讨论了骨骼、关节软骨和角质如何受日粮组成(尤其是维生素和矿物质)的影响。碳水化合物、蛋白质和氨基酸对骨重建的作用尚不明确。常量矿物质(如钙和磷)和维生素D非常重要。镁可能跟钙和磷一样重要。日粮中微量矿物质(如锌、铜、锰和氟等)的不足或过量也会产生不利影响。关节软骨依赖于扩散式营养供应。蛋白多糖和胶原合成受损是发生关节软骨相关疾病的前兆。添加氨基酸,尤其是与微量矿物质(如铜和硅)结合的氨基酸,可以减少软骨病的发生和降低严重程度,但人们至今未找到常量矿物质在关节软骨代谢中的明确作用。微量矿物质,如锌、锰和铁在这些疾病中的作用较小。扩散式营养供应对角质产生过程至关重要,尤其是含硫氨基酸(如半胱氨酸)对角质化非常重要。含有常量和微量矿物质的日粮的可用性和扩散式供应可直接和间接激活负责角蛋白纤维发育和胞间胶结物合成的酶。补充矿物质的同时补充生物素也有利于角质产生。总之,营养是母猪跛足的重要诱发因素,可影响骨骼、关节软骨和角质质量。其调节机制非常复杂,到目前为止人们尚未完全了解。不同营养成分之间经常相互作用,必须保持平衡,因为日粮中摄入不足或过量都可能会扰乱这些过程。唐彩琰(译) 王晶晶(审) M.M.Jvan Riet 2019国外畜牧学(猪与禽)2019,39,9:1
9Associated injuries complicating radial head fractures : a demographic study 显示文摘van Riet RP Morrey BF O'Driscoll SW 2005Clin Orthop2005,,35:1
10A conformationnumber to quantify the degree of conformality in brachytherapy and extemal beam irradiation:Application to the prostate 显示文摘Van'Riet MS Mak AC Moeland MA 1997Int J Ra- diat Oncol Biol Phys1997,37,3:1
11Simultaneous determination of residues of chloram-phenicol, thiamphenicol, florfenicol and florfenicol a-mine in farmed aquatic species by liquid chromatogra-phy/mass spectrometry显示文摘RIET J M POTER R A CHRISTIE-FOUGERE M 2003J AOAC Int2003,86,3:1
12Protease-depend- ent activation of epithelial cells by fungal allergens leads to mor- phologie changes and cytokine production显示文摘Kauffman HF Toraee JF Vande Riet MA 2000J Allergy Clin Im- munol2000,105,6:1
13Aconformation number to quantify the degree of conformality inbrachytherapy and external beam irradiation: application to theprostate显示文摘VAN'T RIET A MAK A C MOERLAND M A 1997Int J Radiat Oncol Biol Phys1997,37,:1
14The incidence of associated fractures of the upper limb in fractures of the radial head 显示文摘Kaas L van Riet RP Vroemen JP 2008Strategies Trauma Limb Reconstr2008,,3:1
15Relationship between A1C and glucose levels in the general Dutch population: the new Hoorn study 显示文摘van't Riet E Alssema M Rijkelijkhuizen JM 2010Diabetes Care2010,33,1:1
16A conformation number to quantify the degree of eonformality in braehytherapy and external beam irradiation, Application to the prostate显示文摘Van't Riet A Mak AC Moerland MA 1907Int J Radiat Oneol Biol Phys1907,37,3:1
17Use of uterine ar-tery doppler ultrasonography to predict pre-eclampsia and in- trauterine growth restriction: a systematic review and bivari- able meta-analysis显示文摘Cnossen J S Morris R K rer Riet G 2008CMAJ2008,178,6:1
18Diagnosis and treatment of portal vein thrombosis following splenectomy 显示文摘Riet MV Burger JWA Muiswinkel JMV 2000Br J Surg2000,87,:1
19Purification of a pluripotent neural stem cellfrom the adult mouse brain显示文摘Riet ze RL Valcanis H Brooker GF 0,,6848:1
20Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization显示文摘Lieben Liesbet Masuyama Ritsuko Torrekens Sophie Van Looveren Riet Schrooten Jan Baatsen Pieter Lafage-Proust Marie-Hélène Dresselaers Tom Feng Jian Q Bonewald Lynda F Meyer Mark B Pike J Wesley Bouillon Roger Carmeliet Geert 2012EN2012,,5:1
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