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| 1 | Regulation of the G1 phase of the mammalian cell cycle显示文摘In any multi-cellular organism, the balance between cell division and cell death maintains a constant cell number. Both cell division cycle and cell death are highly regulated events. Whether the cell will proceed through the cycle or not, depends upon whether the conditions required at the checkpoints during the cycle are fulfilled. In higher eucaryotic cells, such as mammalian cells, signals that arrest the cycle usually act at a G1 checkpoint. Cells that pass this restriction point are committed to complete the cycle. Regulation of the GI phase of the cell cycle is extremely complex and involves many different families of proteins such as retinoblastoma family cyclin dependent kinases, cyclins, and cyclic kinase inhibitors. | DONJERKOVIC DUBRRAVKA DAVID W SCOTT (Department of Immunology, Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD) | 2000 | Cell Research2000，10，1： | 18 |
| 2 | Activation-induced cell death in B lymphocytes显示文摘Upon encountering the antigen (Ag), the immune system can either develop a specific immune response or enter a specific state of unresponsiveness, tolerance. The response of B cells to their specific Ag can be activation and proliferation, leading to the immune response, or anergy and activation-induced cell death (AICD), leading to tolerance. AICD in B lymphocytes is a highly regulated event initiated by crosslinking of the B cell receptor (BCR). BCR engagement initiates several signaling events such as activation of PLCr, Ras, and PI3K, which generally speaking, lead to survival. However, in the absence of survival signals (CD40 or IL-4R engagement), BCR crosslinking can also promote apoptotic signal transduction pathways such as activation of effector caspases, expression of pro-apoptotic genes, and inhibition of pro-survival genes. The complex interplay between survival and death signals determines the B cell fate and, consequently, the immune response. | DONJERKOVIC DUBRAVKA, DAVID W SCOTT (Department of Immunology, Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD, 20855. USA) | 2000 | Cell Research2000，10，3： | 6 |
| 3 | Tool selection for five-axis curvature matched machining显示文摘 | JENSEN C RED W PI J | 2002 | Computer-Aided Design2002，34，： | 1 |
| 4 | Isolation of non-tuberculosis mycobacteria in treated dental unit waterlines显示文摘 | Porteous N B Redding S W Jorgensen J H | | 0，，： | 1 |
| 5 | Tool selection for five-axis curvature matched machining显示文摘 | JENSEN C RED W PI J | 2002 | Computer-Aided Design2002，34，3： | 1 |
| 6 | Isolation of the luteinizing hormone and follicle-stimulating hormone-releasing hormone from porcine hypothalamic显示文摘 | Schally A V Nair R M Redding T W | 1971 | J Biol Chem1971，246，23： | 1 |
| 7 | Tool seleetion for five-axis curvature matehed maehining 显示文摘 | Jensen C G Red W E Pi J | 2002 | Computer-Aided De- sign2002，34，3： | 1 |
| 8 | Vision-based Target Gee-location using a Fixed-wing Minia-ture Air Vehicle显示文摘 | Blake Barber D Joshua D Redding Timothy W McLain | | 0，，04： | 1 |
| 9 | Anticoccidiosis drugs : Lesion - scoring techniques in battery and floor - pen experiments with chicken 显示文摘 | JOHNSON J RED W M | 1970 | Exp Parasitol1970，28，： | 1 |
| 10 | Kinetic parameters from themogravinetric data显示文摘 | Coats A W Red Fern J P | 1964 | Nature1964，201，1： | 1 |
| 11 | Mechanism of electronconduction in self-assembled alkanethiol monolayerdevices显示文摘 | Wang W Lee T Red M A | 2003 | Phys Rev B2003，68，3： | 1 |
| 12 | Inhibition of growth of pancreatic carcinomas in animal models by analogs of hypothalamic hormones显示文摘 | Redding T W Schally A V | 1984 | Proc Natl Acad Sci USA1984，81，： | 1 |
| 13 | Age of acquisition in sPort : starting early matters 显示文摘 | HNRNANDEZ A E MATTARELLA-MICKE A REDDING R W T et al | 2011 | American Journal of Psychology2011，3，： | 1 |
| 14 | Mechanism of electron conduction in self - assembled alkanethiol monolayer devices显示文摘 | WANG W LEE T RED M A | 2003 | Phys Rev B2003，68，03： | 1 |
| 15 | Vision-based target geo-location using a fixed-wing miniature airvehicle 显示文摘 | BARBER D B REDDING J D MCLAIN T W | 2006 | Journal of Intelligent and Robotic Systems2006，47，4： | 1 |
| 16 | Tool selection for five-axis curvature matched machining 显示文摘 | JENSEN C G RED W E PI J | 2002 | Computer-Aided Design2002，34，： | 1 |
| 17 | Growth in-hibition of MXT mammary carcinoma by enhancing programmed cell death (apoptosis) with anlog of LH-RH and somatostatin显示文摘 | Szende B Lapis K Redding T W | 1989 | Breast Cancer Res Treat1989，14，： | 1 |
| 18 | Isolation, structural elucidation and synthesis of a tetradecapeptide with in vitro ACTH-releasing activity corresponding to resi- dues 33-46 of the alpha-chain of porcine hemoglobin 显示文摘 | Schally A V Huang W Y Redding T W | 1978 | Biochemical and Biophysical Research Communications1978，82，2： | 1 |
| 19 | Vision- based target geo-location using a fixed-wing miniature air ve- hicle 显示文摘 | BARBER D B REDDING J D MCLAIN T W | 2006 | Journal of Intelligent and Robotic Systems2006，47，4： | 1 |
| 20 | Optimal low-thrust transfer to synchronous orbit显示文摘 | REDDING D C BREAK W J V | 1984 | Journal of Guidance Control and Dynamics1984，7，2： | 1 |
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