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| 1 | Effect of short-term high-dose atorvastatin on systemic inflammatory response and myocardial ischemic injury in patients with unstable angina pectoris undergoing percutaneous coronary intervention显示文摘 | Sun Fei Yin Zhao Shi Quanxing Zhao Bei Wang Shouli | 2014 | Chinese Medical Journal2014，，21： | 27 |
| 2 | Dendritic Cells Transduced with SOCS1 Gene Exhibit Regulatory DC Properties and Prolong Allograft Survival显示文摘SOCS1 is a key regulator of cytokine signaling and is important for maintaining balance in the immune system. It is thought to participate in negative feedback loops in cytokine signaling and may be an important signal for the regulation of dendritic cell (DC) maturation. However, it remains unclear whether DCs transduced with SOCS1 exhibit characteristics of regulatory DCs and induce allogeneic T-cell hyporesponsiveness. In this study, we constructed adenoviral vector coding SOCS1 (Ad-SOCS1) that can efficiently increase SOCS1 gene expression in bone marrow-derived dendritic cells. DCs transduced with Ad-SOCS1 (DC-SOCS1) expressed low levels of costimulatory and MHC molecules, were resistant to maturation and activation stimulation, induced allogeneic T-cell hyporesponsiveness, and promoted the generation of regulatory-like T cells in vitro. DC-SOCS1 pretreatment significantly prolonged the survival of allografts and led to a substantial increase in the generation of regulatory T cells. Our data suggest that SOCS1 inhibits DC maturation and induces regulatory DC generation, therefore possessing therapeutic potential to prevent rejection in organ transplantation. | Hong Fu Shaohua Song Fang Liu Zhijia Ni Xiaoyun Shen Liang Xiao Guoshan Ding Quanxing Wang | 2009 | Cellular & Molecular Immunology2009，6，2： | 20 |
| 3 | ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer显示文摘 | Shunrong Ji Yi Qin Si Shi Xiangyuan Liu Hongli HU Hu Zhou Jing Gao Bo Zhang Wenyan Xu Jiang Liu Dingkong Liang Liang Liu Chen Liu Jiang Long Haijun Zhou Paul J Chiao Jin Xu Quanxing Ni Daming Gao Xianjun Yu | 2015 | Cell Research2015，25，5： | 19 |
| 4 | Hyperthermic intraperitoneal chemotherapy for gastric cancer with peritoneal metastasis:A multicenter propensity scorematched cohort study显示文摘Objective:Systemic chemotherapy has limited efficacy in the treatment of peritoneal metastasis(PM)in gastric cancer(GC).Hyperthermic intraperitoneal chemotherapy(HIPEC)combined with complete cytoreductive surgery(CRS)has shown promising outcomes but remains controversial.The present study aimed to evaluate the safety and efficacy of HIPEC without CRS in GC patients with PM.Methods:This retrospective propensity score-matched multicenter cohort study included GC patients with PM treated with either chemotherapy alone(Cx group)or with HIPEC combined with chemotherapy(HIPEC-Cx group)in four Chinese high-volume gastric medical centers between 2010 and 2017.The primary outcomes were median survival time(MST)and 3-year overall survival(OS).Propensity score matching was performed to compensate for controlling potential confounding effects and selection bias.Results:Of 663 eligible patients,498 were matched.The MST in the Cx and HIPEC-Cx groups was 10.8 and 15.9 months,respectively[hazard ratio(HR)=0.71,95%confidence interval(95%CI),0.58-0.88;P=0.002].The 3-year OS rate was 10.1%(95%CI,5.4%-14.8%)and 18.4%(95%CI,12.3%-24.5%)in the Cx and HIPEC-Cx groups,respectively(P=0.017).The complication rates were comparable.The time to first flatus and length of hospital stay for patients undergoing HIPEC combined with chemotherapy was longer than that of chemotherapy alone(4.6±2.4 d vs.2.7±1.8 d,P<0.001;14.2±5.8 d vs.11.4±7.7 d,P<0.001),respectively.The median follow-up period was 33.2 months.Conclusions:Compared with standard systemic chemotherapy,HIPEC combined with chemotherapy revealed a statistically significant survival benefit for GC patients with PM,without compromising patient safety. | Ziying Lei Jiahong Wang Zhi Li Baozhong Li Jiali Luo Xuejun Wang Jin Wang MingchenBa Hongsheng Tang Qingjun He Quanxing Liao Xiansheng Yang Tianpei Guan Han Liang Shuzhong Cui | 2020 | Chinese Journal of Cancer Research2020，32，6： | 11 |
| 5 | Effect of Mg/Al atom ratio of support on catalytic performance of Co-Mo/MgO-Al_2O_3 catalyst for water gas shift reaction显示文摘Co-Mo-based catalysts supported on mixed oxide supports MgO-Al2O3 with different Mg/Al atom ratios for water gas shift reaction were studied by means of TPR, Raman, XPS and ESR. It was found that the octahedral Mo species in oxidized Co-Mo/MgO(x)-Al2O3 catalyst and the contents of Mo5+, Mo4+, S2- and S22- species in the functioning catalysts increased with increasing the Mg/Al atom ratio of the support under the studied experimental conditions. This is favorable for the formation of the active Co-Mo-S phase of the catalysts. Catalytic performance testing results showed that the catalysts Co-Mo/MgO-Al2O3 with the Mg/Al atom ratio of the support in the range of 0.475-0.525 exhibited optimal catalytic activity for the reaction. | Yixin Lian Huifang Wang Quanxing Zheng Weiping Fang Yiquan Yang | 2009 | Journal of Natural Gas Chemistry2009，18，2： | 6 |
| 6 | Human BDCA2^+CD123^+CD56^+ dendritic cells (DCs) related to blastic plasmacytoid dendritic cell neoplasm represent a unique myeloid DC subset显示文摘树枝状的房间(DC ) 包括二个机能上地不同的子集:plasmacytoid DC (pDCs ) 和 myeloid DC (mDCs ) 。pDCs 被专攻类型的快速、巨大的分泌物我响应通过使用费的 nucleic 酸的干扰素(IFN-I ) 相似受体(TLR )-7 或 TLR-9。在这份报告,我们描绘了 CD56 < 啜 class= “ a-plus-plus ” >+ DC 人口包括 CD123 和 BDCA2 表示典型 pDC 标记,但是生产与 pDCs 作比较的少得多 IFN-I。另外, CD56 < 啜 class= “ a-plus-plus ” > 和由介绍的染色体宽的 transcriptional 的 mDCs 然而并非 pDCs 的 + DC 簇。因此, CD56 < 啜 class= “ a-plus-plus ” >+ DC 机能上地由在 TLR4 刺激和 priming na 之上生产 IL-12 类似于 mDCs ? 没有优先的激活的 ve T 房间。这些数据建议 CD56 < 啜 class= “ a-plus-plus ” >+ DC 代表与一些 pDC 特征混合的一个新奇 mDC 子集。CD4 < 啜 class= “ a-plus-plus ” >+ CD56 < 啜 class= “ a-plus-plus ” >+ hematological 恶意作为 blastic plasmacytoid 被分类树枝状的房间瘤(BPDCN ) 由于它 pDCs 的典型分子的表示。然而,我们证明 BPDCN 接近 CD56 < 啜 class= “ a-plus-plus ” >+ DC 比由介绍的全球基因表示的 pDCs。因此,我们建议 CD4 < 啜 class= “ a-plus-plus ” >+ CD56 < 啜 class= “ a-plus-plus ” >+ 瘤可以是 CD56 的一个肿瘤对应物 < 啜 class= “ a-plus-plus ” >+ mDCs 然而并非 pDCs。 | Haisheng Yu Peng Zhang Xiangyun Yin Zhao Yin QuanxinG Shi Ya Cui Guanyuan Liu Shouli Wang Pier Paolo Piccaluga Taijiao Jiang Liguo Zhang | 2015 | Protein & Cell2015，6，4： | 6 |
| 7 | STUDY ON THE TREATMENT AND REUSE OF WASTEWATER FROM THE PRODUCTION OF 2-NAPHTHANOL显示文摘Systematic studies on the treatment and reuse of the acid industrial wastewatercontaining Sodium 2-Naphthylsulfonate (β-salt) from 2--Naphthanol of production processby ND--910 resin (made by self)is reported in this paper.Under the operation conditionsof initial β-salt concentration of 10000-25000mg/L and initial CODcr of 2000040000mg/L, the removal rates of Sodium 2-Naphthylsulfonate and CODcr are over 95%and over 89%, respectively. The effluent can be discharged directly after biologicaldegradation. The working sorption capacity of ND-910 Resin for β-salt is over 230g/Kg.An alkali-water wash procedure is utilized to regenerate resin and the reclaiming rate ofβ-salt is over 98%. | Zhang HUICHUN Chen JINLONG Zhang QUANXING(The state key laboratory of pollution control and resource reuse,Nanjing University 210093) | 1999 | Chinese Journal of Reactive Polymers1999，8，1： | 5 |
| 8 | Preparation of polymer-supported hydrated ferric oxide based on Donnan membrane effect and its application for arsenic removal显示文摘In the present study a novel technique was proposed to prepare a polymer-supported hydrated ferric oxide (D201-HFO) based on Donnan membrane effect by using a strongly basic anion exchanger D201 as the host material and FeCl3-HCl-NaCl solution as the reaction environment. D201-HFO was found to exhibit higher capacity for arsenic removal than a commercial sorbent Purolite ArsenX. Furthermore, it presents favorable adsorption selectivity for arsenic removal from aqueous solution, as well as satis- factory kinetics. Fixed-bed column experiments showed that arsenic sorption on D201-HFO could re- sult in concentration of this toxic metalloid element below 10 μg/L, which was the new maximum con- centration limit set recently by the European Commission and imposed by the US EPA and China. Also, the spent D201-HFO is amenable to efficient regeneration by NaOH-NaCl solution. | ZHANG QingJian PAN BingCai CHEN XinQing ZHANG WeiMing PAN BingJun ZHANG QuanXing L.LV X.S.ZHAO | 2008 | Science China Chemistry2008，51，4： | 4 |
| 9 | A multi-institutional retrospective study of hyperthermic plus intravesical chemotherapy versus intravesical chemotherapy treatment alone in intermediate and high risk nonmuscle-invasive bladder cancer显示文摘Objective:To compare the efficacy and safety of hyperthermic intravesical chemotherapy(HIVEC)and intravesical chemotherapy(IVEC)in patients with intermediate and high risk nonmuscle-invasive bladder cancer(NMIBC)after transurethral resection.Methods:We included 560 patients diagnosed with primary or recurrent NMIBC between April 2009 and December 2015 at 1 of 6 tertiary centers.We matched 364 intermediate or high risk cases and divided them into 2 groups:the HIVEC+IVEC group[chemohyperthermia(CHT)composed of 3 consecutive sessions followed by intravesical instillation without hyperthermia]and the IVEC group(intravesical instillation without hyperthermia).The data were recorded in the database.The primary endpoint was 2-year recurrence-free survival(RFS)in all NMIBC patients(n=364),whereas the secondary endpoints were the assessment of radical cystectomy(RC)and 5-year overall survival(OS).Results:There was a significant difference in the 2-year RFS between the two groups in all patients(n=364;HIVEC+IVEC:82.42%vs.IVEC:74.18%,P=0.038).Compared with the IVEC group,the HIVEC+IVEC group had a lower incidence of RC(P=0.0274).However,the 5-year OS was the same between the 2 groups(P=0.1434).Adverse events(AEs)occurred in 32.7%of all patients,but none of the events was serious(grades 3–4).No difference in the incidence or severity of AEs between each treatment modality was observed.Conclusions:This retrospective study showed that HIVEC+IVEC had a higher 2-year RFS and a lower incidence of RC than IVEC therapy in intermediate and high risk NMIBC patients.Both treatments were well-tolerated in a similar manner. | Qiang Ruan Degang Ding Bin Wang Chaohong He Xuequn Ren Zhenhua Feng Zhigang Pang Jin Wang Xiangliang Zhang Hongsheng Tang Jiahong Wang Qingjun He Ziying Lei Quanxing Liao Jiali Luo Shuzhong Cui | 2021 | Cancer Biology & Medicine2021，18，1： | 4 |
| 10 | Apoptotic cell administration enhances pancreatic islet engraftment by induction of regulatory T cells and tolerogenic dendritic cells显示文摘Apoptotic 房间转移被发现了能便于 allograft 的嫁接。然而,内在的机制尚待充分被理解。这里,我们证明施主 apoptotic splenocytes 的静脉内的管理能由导致 tolerogenic 的产生支持胰腺的小岛嫁接树枝状的房间(Tol-DCs ) 和 CD4 + Foxp3 + 规章的 T 房间(Tregs ) 。在 vivo,树枝状的房间(DC ) 或 Tregs 的清理由 apoptotic 房间管理阻止了有免疫力的忍耐的正式就职。用 anti-CD25 的 Tregs 的短暂消除, monoclonal 抗体(mAb ) 在 apoptotic splenocytes 的管理以后废除了 Tol-DCs 的产生。相互地,在用白喉毒素(DT ) 的 CD11c 数据终端就绪老鼠以内的 DC 的弄空与 apoptotic splenocytes 的管理在接受者阻止了 Tregs 的产生。在二个房间之间的房间接触打的由直接要求,并且规划了死亡 1 ligand (PD-L1 ) 的 Tol-DCs 的 Tregs 的正式就职在 Tregs 扩大起了重要作用。Apoptotic 房间管理没能在 IL-10-deficient 和 Smad3 缺乏的老鼠导致 Tol-DCs,建议那 IL-10 和转变生长 factor-β(TGF-β) 被需要处于 tolerogenic 状态维持 DC。因此,我们证明 Tol-DCs 在他们的表面上并且相互地经由 PD-L1 支持 Tregs 的扩大 Tregs 便于 Tol-DCs 维持 apoptotic 房间经由 secreting IL-10 和 TGF-β 导致的移植忍耐;。 | Cong Wu Yi Zhang Yingnling Jiang Quanxing Wang Yao Long Chunmei Wang Xuetao Cao Guoyou Chen | 2013 | Cellular & Molecular Immunology2013，10，5： | 4 |
| 11 | THEATMENT OF WASTEWATER FROM PRODUCTION PROCESS OF 2,3-ACID显示文摘Wastewater from production process of 2,3-acid was treated by adsorption usingmacroporous resin NDA-708. After only one-step treatment by resin adsorption, removalefficiency of three kinds of naphthalene chemicals was above 99%, removal efficiency ofCODcr was above 96% Under proper operating condition, desorption efficiency wasaround 100%. The running records of the industrial facility showed that the naphthlenechemicals in desorption effluent could be reused without obvious influence on the qualityOf the product. | FENG Wenguo ZHANG Quanxing CHEN Jinlong XU Zhaoyi PAN Bingcai SU Xing(Dept. of Environ. Sci. & Techn., Nanjing Univ ersity Nanjing 210093, ChinaDitong Chemical Corporation, Suzhou, 215124) | 1999 | Chinese Journal of Reactive Polymers1999，8，1： | 4 |
| 12 | Energy sources identify metabolic phenotypes n pancreatic cancer显示文摘 | Chen Liang Yi Qin Bo Zhang Shunrong Ji Si Shi Wenyan Xu Jiang Liu Jinfeng Xiang Dingkong Liang Qiangsheng Hu Liang Liu Chen Liu Guopei Luo Quanxing Ni Jin xu Xianjun Yu | 2016 | Acta Biochimica et Biophysica Sinica2016，48，11： | 3 |
| 13 | ADSORPTION OF PHENOL AND Pb^(2+) FROM AQUEOUS SOLUTIONS BY A NEW DI-FUNCTION ADSORBENT WITH SULFHYDRYL GROUPS显示文摘A new di-function adsorbent (JN-3) was prepared by sulfhydryl modified. Comparing with Amberlite XAD-4 and NDA-150, the equilibrium adsorption for phenol on the JN-3 from aqueous solutions was tested, perfect adsorption capacity was shown. Pb2+ can be also removed by JN-3 because of the chelate interaction between sulfhydryl groups and metal ions. This adsorbent could be used in removal of combine pollutants such as phenolic compounds and heavy metal ions from waste streams. | WANG Jinnan LI Aimin ZHANG Bo ZHANG Quanxing | 2007 | Chinese Journal of Reactive Polymers2007，16，1： | 3 |
| 14 | TREATMENT AND RESOURSE REUSE OF INDUSTRIAL WASTEWATER FROM PRODUCTION PROCESS OF PHENYL ACETIC ACID显示文摘The effluent from phenyl acetic acid (PhCH2COOH) production process can betreated with NDA-999 macroporous polymeric adsorbent with about 100% removalefficiency of PhCH2COOK benzyl alcohol (PhCH2OH)and benzaldehyde (PhCHO) aswell as the decrease in Total Organic Carbon (TOC)from 4691mg/l to <300mg/L. 3. 7kgPhCH2COOH and 120kg NaCl will be recovered from per m3 wastewater and theadsorbent can be reused after being regenerated by NaOH aqueous solution andmethanol. Good economic, social and environmental results can be achieved with thismethod. | PAN Bingcai CHEN Jinlong ZHANG Quanxing WANG Yong(State Key Laboratory of Pollution Control & Resource Reuse, Department of EnvironmentalScience & Engineering, Nanjing University Nanjing 210093, P R. China) | 1999 | Chinese Journal of Reactive Polymers1999，8，1： | 3 |
| 15 | Heavy metal removal from water/wastewater by nanosized metal oxides: A review显示文摘 | Ming Hua Shujuan Zhang Bingcai Pan Weiming Zhang Lu Lv Quanxing Zhang | 2011 | Journal of Hazardous Materials2011，，： | 2 |
| 16 | Magnetic functionalised carbon nanotubes as drug vehicles for cancer lymph node metastasis treatment显示文摘 | Feng Yang Chen Jin Dong Yang Yongjian Jiang Ji Li Yang Di Jianhua Hu Changchun Wang Quanxing Ni Deliang Fu | 2011 | European Journal of Cancer2011，，12： | 2 |
| 17 | Validation of polymer-based nano-iron oxide in further phosphorus removal from bioeffluent: laboratory and scaled- up study显示文摘 | Ming HUA Lili XIAO Bingcai PAN Quanxing ZHANG | 2013 | Frontiers of Environmental Science & Engineering2013，7，3： | 2 |
| 18 | Pancreatic adenocarcinoma: dynamic 64-slice helical CT with perfusion imaging显示文摘 | Jin Xu Zonghui Liang Sijie Hao Li Zhu Maskay Ashish Chen Jin Deliang Fu Quanxing Ni | 2009 | Abdominal Imaging2009，，6： | 2 |
| 19 | Green synthesis of enantiomerically pure l -lactide and d -lactide using biogenic creatinine catalyst显示文摘 | Wei Huang Yunbiao Qi Na Cheng Xupeng Zong Tianrong Zhang Wei Jiang Hong Li Quanxing Zhang | 2014 | Polymer Degradation and Stability2014，，： | 1 |
| 20 | Meehansis of multipleorgan damages in acute necrotizing panereatitis显示文摘 | Ni Quanxing Caiduan | 2001 | Chinese Medical Jomal2001，114，7： | 1 |
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