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| 1 | Dissimilatory Fe(Ⅲ) reduction characteristics of paddy soil extract cultures treated with glucose or fatty acids显示文摘Dissimilatory Fe(Ⅲ) reduction is a universal process with irreplaceable biological and environmental importance in anoxic environments. Our knowledge about Fe(Ⅲ) reduction predominantly comes from pure cultures of dissimilatory Fe(Ⅲ) reducing bacteria (DFRB). The objective of this study was to compare the effects of glucose and a selection of short organic acids (citrate, succinate, pyruvate, propionate, acetate, and formate) on Fe(Ⅲ) reduction via the anaerobic culture of three paddy soil solutions with Fe(OH)3 as the sole electron acceptor. The results showed significant differences in Fe(Ⅲ) reduction among the three paddy soil solutions and substrate types. Bacteria from the Sichuan paddy soil responded quickly to substrate supply and showed higher Fe(Ⅲ) reducing activity than the other two soil types. Bacteria in the Jiangxi paddy soil culture solution could not use propionate as a source of electrons for Fe(Ⅲ) reduction. Similarly, bacteria in the Jilin paddy soil culture could not use succinate effectively. Pyruvate was readily used by cultures from all three paddy soil solutions, thus indicating that there were some similarities in substrate utilization by bacteria for Fe(Ⅲ) reduction. The use of glucose and citrate as substrate for dissimilatory Fe(Ⅲ) reduction indicates important ecological implications for this type of anoxic respiration. | HE Jiangzhou1,2, QU Dong1, 1. College of Resources and Environment, Northwest A & F University, Yangling, Shaanxi 712100, China.2. Xinjiang Production & Construction Corps Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin, Tarim University, Alar, Xinjiang Uygur Autonomous Region, Xinjiang 843300, China | 2008 | Journal of Environmental Sciences2008，20，9： | 24 |
| 2 | Chronic myeloid leukemia-from the Philadelphia chromosome to specific target drugs:A literature review显示文摘Chronic myeloid leukemia(CML)is a myeloproliferative neoplasm and was the first neoplastic disease associated with a well-defined genotypic anomaly―the presence of the Philadelphia chromosome.The advances in cytogenetic and molecular assays are of great importance to the diagnosis,prognosis,treatment,and monitoring of CML.The discovery of the breakpoint cluster region(BCR)-Abelson murine leukemia(ABL)1 fusion oncogene has revolutionized the treatment of CML patients by allowing the development of targeted drugs that inhibit the tyrosine kinase activity of the BCR-ABL oncoprotein.Tyrosine kinase inhibitors(known as TKIs)are the standard therapy for CML and greatly increase the survival rates,despite adverse effects and the odds of residual disease after discontinuation of treatment.As therapeutic alternatives,the subsequent TKIs lead to faster and deeper molecular remissions;however,with the emergence of resistance to these drugs,immunotherapy appears as an alternative,which may have a cure potential in these patients.Against this background,this article aims at providing an overview on CML clinical management and a summary on the main targeted drugs available in that context. | Mariana Miranda Sampaio Maria Luísa Cordeiro Santos Hanna Santos Marques Vinícius Lima de Souza Gonçalves Glauber Rocha Lima Araújo Luana Weber Lopes Jonathan Santos Apolonio Camilo Santana Silva Luana Kauany de SáSantos Beatriz Rocha Cuzzuol Quézia Estéfani Silva Guimarães Mariana Novaes Santos Breno Bittencourt de Brito Filipe Antônio França da Silva Márcio Vasconcelos Oliveira Cláudio Lima Souza Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，2： | 3 |
| 3 | Successful operation of a cooperative SLR station of China and Argentina in San Juan显示文摘We introduced the observations and researches using a Satellite Laser Ranging (SLR) system with high precision, which was designed and made in China and installed in the Observatory of San Juan Uni- versity, Argentina, the capability of the system and the achievement of the cooperative procedure be- tween China and Argentina. The SLR station in San Juan, set up by China and Argentina, is quite sig- nificant for improving the distribution of SLR stations and enhancing the orbital coverage of the whole earth. Since the SLR system started to work in the Observatory of San Juan University in the beginning of 2006, the operation is rather good, and rich data with high precision have been obtained. Further plan of the cooperation for the near future is also presented. | HAN YanBen LIU WeiDong E ACTIS R PODESTA WANG TanQiang GUO TangYong QU Feng A M PACHECO A A GONZALEZ E ALONSO XIANG QingGe HUANG DongPing YIN ZhiQiang | 2008 | Chinese Science Bulletin2008，53，16： | 2 |
| 4 | Hepatology|过氧化物酶体增殖物激活受体α通过YAP-TEAD信号通路促进肝脏增大和肝脏再生显示文摘过氧化物酶体增殖物激活受体α(PPARα)是内/外源物质代谢调控的关键核受体之一。Yes相关蛋白(YAP)是Hippo信号通路的核心调节元件,YAP激活后入核与转录因子TEAD结合,启动下游基因表达,对肝脏大小起到重要调控作用。PPARα激动可致肝增大并在肝再生过程中发挥关键作用,但具体机制仍不清楚。该研究旨在揭示PPARα通过YAP-TEAD信号通路促进肝增大和肝再生的分子调节机制。 | 毕惠嫦 范仕成 高悦 FAN S GAO Y QU A | 2022 | 临床肝胆病杂志2022，38，2： | 2 |
| 5 | NEW TOXOPLASMA GONDII GENOTYPES ISOLATED FROM FREE-RANGE CHICKENS FROM THE FERNANDO DE NORONHA, BRAZIL: UNEXPECTED FINDINGS显示文摘 | Dubey J P Rajendran C Costa D G C Ferreira L R Kwok O C H Qu D Su C Marvulo M F V Alves L C Mota R A Silva J C R | 2010 | The Journal of Parasitology2010，，4： | 2 |
| 6 | An improved rice transformation system using the biolistic method显示文摘 | Li L C Qu R D de Kochko A Fauquet C Beachy R N | 1993 | PlantCell Rep1993，12，： | 1 |
| 7 | Root growth characteristics,biomass and nutrient dynamics of seedlings of two Larch species raised under different fertilization regimes显示文摘 | Qu L Quroreshi A Koike T | 2003 | Plant and Soil2003，，255： | 1 |
| 8 | Bcl-2 antiapoptotic proteins inhibit Beelin 1-dependent aumphagy显示文摘 | Pattingre S Tassa A Qu X | 2005 | Cell2005，122，6： | 1 |
| 9 | Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy显示文摘 | Pattingre S Tassa A Qu X | 2005 | Cell2005，122，6： | 1 |
| 10 | Erythropoietin improves histological and functional outcomes after traumatic brain injury in mice in the absence of the neural erythropoietin receptor显示文摘 | Xiong Y Mahmood A Qu C | | 0，，1： | 1 |
| 11 | A mean variance model to optimize the fixed versus open appointment percentages in open access scheduling systems显示文摘 | Qu x Rardin R L Williams J A S | 2012 | Decision Support Systems2012，53，3： | 1 |
| 12 | Tendon gradient mineralization for tendon to bone interface integration 显示文摘 | Jin QU Andrew R Thoreson A | 2013 | J Orthop Res2013，1131，11： | 1 |
| 13 | Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy 显示文摘 | Pattingre S Tassa A Qu x | 2005 | Cell2005，122，6： | 1 |
| 14 | Degradation of azo dye Acid Red 14 in aqueous solution by electrokinetic and electrooxidation process 显示文摘 | Wang A Qu J Liu H | 2004 | Chemosphere2004，55，9： | 1 |
| 15 | Simulation and Experimental Investigation of the End Milling Process Considering the Cutter Flexibility显示文摘 | Xu A P Qu Y X Zhang D W | 2003 | International Journal of Machine Tools and Manufacture2003，43，3： | 1 |
| 16 | Incorporation of fluorine ions into hydroxyapatite by a pH cycling method 显示文摘 | Qu H Vasiliev A L Aindow M | 2005 | J Mater Sci: Mater Med2005，16，5： | 1 |
| 17 | Ge- netic diversity and drug resistance among newly diagnosed and antiretroviral treatment-naive HIV-infected individuals in western Yunnan: a hot area of viral recombination in China 显示文摘 | Chen M Ma Y Duan S Xing H Yao S Su Y Luo H Yang L Chen H Fu L Qu A Ou CY Jia M Lu L | 2012 | BMC Infect Dis2012，12，： | 1 |
| 18 | Phylogenetic analysis of the vertebrate glycoprotein hormone family including new sequences of sturgeon (Acipenser baeri) β subunits of the two gonadotropins and the thyroid-stimulating hormone显示文摘 | Quérat B Sellouk A Salmon C | | 0，，01： | 1 |
| 19 | Influence of photonic stop band effect on photoluminescence of Y2O3:Eu3+ inverse opal films显示文摘 | Qu X S Dong B A Pan G H | | 0，，1： | 1 |
| 20 | Spotted leaf11,a negative regulator of plant cell death and defense,encodes a Ubox/armadillo repeat protein endowed with E3 ubiquitin ligase activity显示文摘 | Zeng LR Qu S Bordeos A | 2004 | The Plant Cell Online2004，16，10： | 1 |
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