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| 1 | Transplant outcomes of 100 cases of living-donor ABO-incompatible kidney transplantation显示文摘Background:Although ABO-incompatible(ABOi)kidney transplantation(KT)has been performed successfully,a standard preconditioning regimen has not been established.Based on the initial antidonor ABO antibody titers,an individualized preconditioning regimen is developed,and this study explored the efficacy and safety of the regimen.Methods:From September 1,2014,to September 1,2020,we performed 1668 consecutive living-donor KTs,including 100 ABOi and 1568 ABO-compatible(ABOc)KTs.ABOi KT recipients(KTRs)with a lower antibody titer(≤1:8)were administered oral immunosuppressive drugs(OIs)before KT,while patients with a medium titer(1:16)received OIs plus antibody-removal therapy(plasma exchange/double-filtration plasmapheresis),patients with a higher titer(≥1:32)were in addition received rituximab(Rit).Competing risk analyses were conducted to estimate the cumulative incidence of infection,acute rejection(AR),graft loss,and patient death.Results:After propensity score analyses,100 ABOi KTRs and 200 matched ABOc KTRs were selected.There were no significant differences in graft and patient survival between the ABOi and ABOc groups(P=0.787,P=0.386,respectively).After using the individualized preconditioning regimen,ABOi KTRs showed a similar cumulative incidence of AR(10.0%vs.10.5%,P=0.346).Among the ABOi KTRs,the Rit-free group had a similar cumulative incidence of AR(P=0.714)compared to that of the Rittreated group.Multivariate competing risk analyses revealed that a Rit-free regimen reduced the risk of infection(HR:0.31;95%CI:0.12–0.78,P=0.013).Notably,antibody titer rebound was more common in ABOi KTRs receiving a Rit-free preconditioning regimen(P=0.013)than those receiving Rit.ABOi KTRs with antibody titer rebound had a 2.72-fold risk of AR(HR:2.72,95%CI:1.01–7.31,P=0.048).ABOi KTRs had similar serum creatinine and estimated glomerular filtration rate compared to those of ABOc KTRs after the first year.Conclusions:An individualized preconditioning regimen can achieve comparable graft and patient survival rates in ABOi KT with ABOc KT.Rit-free preconditioning effectively prevented AR without increasing the risk of infectious events in those with lower initial titers;however,antibody titer rebound should be monitored. | Saifu Yin Qiling Tan Youmin Yang Fan Zhang Turun Song Yu Fan Zhongli Huang Tao Lin Xianding Wang | 2022 | Chinese Medical Journal2022，135，19： | 7 |
| 2 | The relationships of vitamin D, vitamin D receptor gene polymorphisms, and vitamin D supplementation with Parkinson's disease显示文摘In recent years,many studies have investigated the correlations between Parkinson's disease(PD)and vitamin D status,but the conclusion remains elusive.The present review focuses on the associations between PD and serum vitamin D levels by reviewing studies on the associations of PD with serum vitamin D levels and vitamin D receptor(VDR)gene polymorphisms from PubMed,Web of Science,Cochrane Library,and Embase databases.We found that PD patients have lower vitamin D levels than healthy controls and that the vitamin D concentrations are negatively correlated with PD risk and severity.Furthermore,higher vitamin D concentrations are linked to better cognitive function and mood in PD patients.Findings on the relationship between VDR gene polymorphisms and the risk of PD are inconsistent,but the Fokl(C/M)polymorphism is significantly linked with PD.The occurrence of Fokl(CT)gene polymorphism may influence the risk,severity,and cognitive ability of PD patients,while also possibly influencing the effect of Vitamin D3 supplementation in PD patients.In view of the neuroprotective effects of vitamin D and the close association between vitamin D and dopaminergic neurotransmission,interventional prospective studies on vitamin D supplementation in PD patients should be conducted in the future. | Lingling Lv Xuling Tan Xinke Peng Rongrong Bai Qile Xiao Ting Zou Jieqiong Tan Hainan Zhang Chunyu Wang | 2020 | Translational Neurodegeneration2020，9，3： | 5 |
| 3 | Predicting the growth performance of growing-finishing pigs based on net energy and digestible lysine intake using multiple regression and artificial neural networks models显示文摘Backgrounds:Evaluating the growth performance of pigs in real-time is laborious and expensive,thus mathematical models based on easily accessible variables are developed.Multiple regression(MR)is the most widely used tool to build prediction models in swine nutrition,while the artificial neural networks(ANN)model is reported to be more accurate than MR model in prediction performance.Therefore,the potential of ANN models in predicting the growth performance of pigs was evaluated and compared with MR models in this study.Results:Body weight(BW),net energy(NE)intake,standardized ileal digestible lysine(SID Lys)intake,and their quadratic terms were selected as input variables to predict ADG and F/G among 10 candidate variables.In the training phase,MR models showed high accuracy in both ADG and F/G prediction(R^(2)_(ADG)=0.929,R^(2)_(F/G)=0.886)while ANN models with 4,6 neurons and radial basis activation function yielded the best performance in ADG and F/G prediction(R^(2)_(ADG)=0.964,R^(2)_(F/G)=0.932).In the testing phase,these ANN models showed better accuracy in ADG prediction(CCC:0.976 vs.0.861,R^(2):0.951 vs.0.584),and F/G prediction(CCC:0.952 vs.0.900,R^(2):0.905 vs.0.821)compared with the MR models.Meanwhile,the“over-fitting”occurred in MR models but not in ANN models.On validation data from the animal trial,ANN models exhibited superiority over MR models in both ADG and F/G prediction(P<0.01).Moreover,the growth stages have a significant effect on the prediction accuracy of the models.Conclusion:Body weight,NE intake and SID Lys intake can be used as input variables to predict the growth performance of growing-finishing pigs,with trained ANN models are more flexible and accurate than MR models.Therefore,it is promising to use ANN models in related swine nutrition studies in the future. | Li Wang Qile Hu Lu Wang Huangwei Shi Changhua Lai Shuai Zhang | 2022 | Journal of Animal Science and Biotechnology2022，13，6： | 5 |
| 4 | Precise orbit determination for BDS satellites显示文摘Since the frst pair of BeiDou satellites was deployed in 2000,China has made continuous eforts to establish its own independent BeiDou Navigation Satellite System(BDS)to provide the regional radio determination satellite service as well as regional and global radio navigation satellite services,which rely on the high quality of orbit and clock products.This article summarizes the achievements in the precise orbit determination(POD)of BDS satellites in the past decade with the focus on observation and orbit dynamic models.First,the disclosed metadata of BDS satellites is presented and the contribution to BDS POD is addressed.The complete optical properties of the satellite bus as well as solar panels are derived based on the absorbed parameters as well the material properties.Secondly,the status and tracking capabilities of the L-band data from accessible ground networks are presented,while some low earth orbiter satellites with onboard BDS tracking capability are listed.The topological structure and measurement scheme of BDS Inter-Satellite-Link(ISL)data are described.After highlighting the progress on observation models as well as orbit perturbations for BDS,e.g.,phase center corrections,satellite attitude,and solar radiation pressure,diferent POD strategies used for BDS are summarized.In addition,the urgent requirement for error modeling of the ISL data is emphasized based on the analysis of the observation noises,and the incompatible characteristics of orbit and clock derived with L-band and ISL data are illuminated and discussed.The further researches on the improvement of phase center calibration and orbit dynamic models,the refnement of ISL observation models,and the potential contribution of BDS to the estimation of geodetic parameters based on L-band or ISL data are identifed.With this,it is promising that BDS can achieve better performance and provides vital contributions to the geodesy and navigation. | Qile Zhao Jing Guo Chen Wang Yifei Lyu Xiaolong Xu Chao Yang Junqiang Li | 2022 | Satellite Navigation2022，3，1： | 4 |
| 5 | Non-Darcy flow seepage characteristics of saturated broken rocks under compression with lateral constraint显示文摘sing an MTS816.03 test system and self-designed seepage apparatus,seepage tests of saturated broken rocks were conducted,and the influence of lithology,axial stress,grain size distribution and loading rate on seepage characteristics was analyzed.The results show that:(1) Under the same axial stress(12 MPa)the permeability of different lithologic samples increases in the order:gangue < mudstone < sand stone < limestone.The permeability of gangue is 3 magnitudes lower than that of limestone.The absolute value of the non-Darcy coefficient β increases in the order:limestone < sandstone < mudstone < gangue The non-Darcy coefficient β of limestone,which is positive,is 5 magnitudes lower than that of gangue.(2)With increasing axial stress,the permeability of saturated broken sandstone decreases,and the absolute value of the non-Darcy coefficient β increases.After the axial stress exceeds 12 MPa,the curves of perme ability and non-Darcy coefficient β all tend to be stable.(3) With increasing Talbol power exponent,the permeability increases,and the absolute value of the non-Darcy coefficient β decreases.(4) With increas ing loading,the permeability increases,and the absolute value of the non-Darcy coefficient β decreases When the loading rate is 0.5 kN/s,the non-Darcy coefficient β is positive. | Yu Bangyong Chen Zhanqing Ding Qile Wang Luzhen | 2016 | International Journal of Mining Science and Technology2016，26，6： | 2 |
| 6 | 2020 Roadmap on gas-involved photo-and electro-catalysis显示文摘Green reactions not only provide us chemical products without any pollution,but also offer us the viable technology to realize difficult tasks in normal conditions.Photo-,photoelectro-,and electrocatalytic reactions are indeed powerful tools to help us to embrace bright future.Especially,some gas-involved reactions are extremely useful to change our life environments from energy systems to liquid fuels and cost-effective products,such as H2 evolution(H2 production),02 evolution/reduction,CO2 reduction,N2 reduction(or N2 fixation) reactions.We can provide fuel cells clean H2 for electric vehicles from H2 evolution reaction(HER),at the same time,we also need highly efficient 02 reduction reaction(ORR) in fuel cells for improving the reaction kinetics.Moreover,we can get the clean oxidant O2 from water through O2 evolution reaction(OER),and carry out some reactions without posing any pollution to reaction systems.Furthermore,we can translate the greenhouse gas CO2 into useful liquid fuels through CO2 reduction reaction(CRR).Last but not the least,we can get ammonia from N2 reduction reaction(NRR),which can decrease energy input compared to the traditional Hubble process.These reactions,such as HER,ORR,OER,CRR and NRR could be realized through solar-,photoelectro-and electro-assisted ways.For them,the catalysts used play crucial roles in determining the efficiency and kinds of products,so we should consider the efficiency of catalysts.However,the cost,synthetic methods of catalysts should also be considered.Nowadays,significant progress has been achieved,however,many challenges still exist,reaction systems,catalysts underlying mechanisms,and so on.As extremely active fields,we should pay attention to them.Under the background,it has motivated us to contribute with a roadmap on ’GasInvolved Photo-and Electro-Catalysis’. | Yulu Yang Yang Tang Haomin Jiang Yongmei Chen Pingyu Wan Maohong Fan Rongrong Zhang Sana Ullah Lun Pan Ji-Jun Zou Mengmeng Lao Wenping Sun Chao Yang Gengfeng Zheng Qiling Peng Ting Wang Yonglan Luo Xuping Sun Alexander S.Konev Oleg V.Levin Panagiotis Lianos Zhuofeng Hu Zhurui Shen Qinglan Zhao Ying Wang Nadia Todorova Christos Trapalis Matthew V.Sheridan Haipeng Wang Ling Zhang Songmei Sun Wenzhong Wang Jianmin Ma | 2019 | Chinese Chemical Letters2019，30，12： | 1 |
| 7 | The impact of atmospheric CO 2 concentration enrichment on rice quality – A research review显示文摘 | Yunxia Wang Michael Frei Qiling Song Lianxin Yang | 2011 | Acta Ecologica Sinica2011，，6： | 1 |
| 8 | d(GC)n repeats form Z-DNA within promoter region and repress the promoter activity in Escherichia coil显示文摘 | Shenghe Huang Chuxin Wu Dongming Li Haizhou Wang Zechang Rao Qiling Shen Chunxiang Chen Yong Liu Xun Xu Chengyu Hu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，7： | 1 |
| 9 | Bioinspired Adaptive,Elastic,and Conductive Graphene Structured Thin-Films Achieving High-Efficiency Underwater Detection and Vibration Perception显示文摘Underwater exploration has been an attractive topic for understanding the very nature of the lakes and even deep oceans.In recent years,extensive efforts have been devoted to developing functional materials and their integrated devices for underwater information capturing.However,there still remains a great challenge for water depth detection and vibration monitoring in a high-efficient,controllable,and scalable way.Inspired by the lateral line of fish that can sensitively sense the water depth and environmental stimuli,an ultrathin,elastic,and adaptive underwater sensor based on Ecoflex matrix with embedded assembled graphene sheets is fabricated.The graphene structured thin film is endowed with favourable adaptive and morphable features,which can conformally adhere to the structural surface and transform to a bulged state driven by water pressure.Owing to the introduction of the graphene-based layer,the integrated sensing system can actively detect the water depth with a wide range of 0.3-1.8 m.Furthermore,similar to the fish,the mechanical stimuli from land(e.g.knocking,stomping)and water(e.g.wind blowing,raining,fishing)can also be sensitively captured in real time.This graphene structured thin-film system is expected to demonstrate significant potentials in underwater monitoring,communication,and risk avoidance. | Qiling Wang Peng Xiao Wei Zhou Yun Liang Guangqiang Yin Qiu Yang Shiao-Wei Kuo Tao Chen | 2022 | Nano-Micro Letters2022，14，4： | 1 |
| 10 | Role of real-time three-dimensional transesophageal echocardiography in mitral valve repair显示文摘Background and objective Pre-operative assessment of mitral valve (MV) anatomy is essential to surgical design in patients undergoing MV repair.Although 2-dimensional (2D) echocardiography provides precise information regarding MV anatomy,RT-3D TEE could increase the understanding of MV apparatus and individual scallop identification.We aimed to investigate the value of RT- 3DTEE in MV repair.Methods RT-3DTEE was performed in six patients with mitral valve prolapse (MVP) by using Philips 1E33 with X7-2t probe.Preoperative RT-3DTEE studies were compared with surgical findings in patients undergoing surgical mitral valve repair,and quantitative evaluation was performed by QLab 6.0 software before and after surgical mitral valve repair.Results RT- 3DTEE could display dynamic morphology of MV,the location of prolapse,and spatial relation to the surrounding tissue.It could provide surgical views of the valves and the valvular apparatus.These results were consistent with surgical findings.The quantitative evaluation before and after surgical MV repair indicated that anterolateral to posteromedial diameter of annulus,anterior to posterior diameter of annulus,perimeter of annulus,and area of annulus in projection plane were significantly smaller after operation compared with those before operation (P<0.05).The length of posterior leaflet,the area of anterior and posterior leaflet,the maximal prolapse height,the volume of leaflet prolapse and the length of coaptation in projection plane were significantly reduced after operation (P<0. 05).Conclusion RT-3DTEE is a unique new modality for rapid and accurate evaluation ofmitral valve prolapse and mitral valve repair. | Cuizhen Pan~1 Xianhong Shu~1 Qiling Cao~2 Chunsheng Wang~1 Wenjun Ding~1 Haozhu Chen~1 1 Department of Echocardiography, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai 200032, China, 2 Rush University Medical Center, Chicago, USA | 2008 | Journal of Geriatric Cardiology2008，5，3： | 1 |
| 11 | Design of a novel mitochondria targetable turn-on fluorescence probe for hydrogen peroxide and its two-photon bioimaging applications显示文摘Considering that hydrogen peroxide(H2O2)plays significant roles in oxidative stress,the cellular signal transduction and essential biological process regulation,the detection and imaging of H2O2 in living systems undertakes critical responsibility.Herein,we have developed a novel two-photon fluorescence turn on probe,named as Pyp-B for mitochondria H2O2 detection in living systems.Selectivity studies show that probe Pyp-B exhibit highly sensitive response toward H2O2 than other reactive oxygen species(ROS)and reactive nitrogen species(RNS)as well as biologically relevant species.The fluorescence colocalization studies demonstrate that the probe can localize in the mitochondria solely.Furthermore,as a bio-compatibility molecule,the highly selective and sensitive of fluorescence probe Pyp-B have been confirmed by its cell imaging application of H2O2 in living A549 cells and zebrafishes under the physiological conditions. | Kangnan Wang Wen Ma Yuchun Xu Xin Liu Gui Chen Meng Yu Qiling Pan Chaobo Huang Xiaochuan Li Qingchun Mu Yongbing Sun Zhiqiang Yu | 2020 | Chinese Chemical Letters2020，31，12： | 1 |
| 12 | Accelerated test method for cementstrength based on the weighted maturity theory 显示文摘 | Luo Qiling Wang Weilun | 2012 | AppliedMechanics and Materials2012，，： | 1 |
| 13 | Leaf phenology rather than mycorrhizal type regulates soil nematode abundance,but collectively affects nematode diversity in seven common subtropical tree species显示文摘The underlying mechanisms of the relationships between tree species and the soil micro-food web in forest ecosystems remain uncertain,primarily ascribed to an insufficient understanding on how tree functional traits drive soil nematode communities,including in subtropical forests.We investigated the impacts of seven subtropical tree species(evergreen:Pinus massoniana,Mytilaria laosensis,Ilex chinensis,Michelia macclurei;and deciduous:Liquidambar formosana,Quercus acutissima,and Betula luminifera)on the soil nematode communities.We found that the abundance of soil nematodes was not affected by mycorrhizal types,but it was around 83%higher under the deciduous trees than the evergreen trees,indicating the importance of leaf phenology to the abundance of soil nematodes.Nonetheless,both the evergreen and the arbuscular mycorrhizal trees increased soil nematode diversity,resulting from changes in root traits and soil properties.Furthermore,root traits(root C,root N,and root C:N ratio),and soil properties(total C,total N,moisture content,and bulk density)were the best predictors of the community composition of soil nematodes,indicating a key role of resource quality and soil microhabitat in regulating soil nematodes.In contrast,the ectomycorrhizal trees had lower plant parasite and Wasilewska indices,and evenness,whereas the evergreen trees slightly improved the evenness of soil nematodes.This study suggests that tree species affect the soil food web through changes in soil conditions and plant functional traits in subtropical forests. | Jianqing Wang Jiaoyan Mao Yunyan Tan Shu Kee Lam Qiling Guo Xiuzhen Shi | 2023 | Forest Ecosystems2023，10，2： | 0 |
| 14 | Geometrical Design and Hydraulic Feasibility of Inner-Reinforced Girders in Hydropower Bifurcations显示文摘Inner-reinforced girders, also known as ribs, are widely used in hydropower bifurcations. However, while they strengthen structures, they also cause energy loss. This work aims to develop an appropriate geometry form for ribs that can diminish head loss in hydropower bifurcations. The term rib/breadth ratio(RBR) is defined to describe the geometrical form of ribs. An investigation is conducted to study the flow and performance characteristics of bifurcations with ribs using computational fluid dynamics. The dependence of the head loss coefficient on the RBR is given in six working conditions. Results show that the ribs change the local flow patterns and slightly increase the water head loss in some cases. In other cases,however, the ribs make the flow smooth. An appropriate RBR is the key to improve the flow patterns in hydropower bifurcations. The head loss varies with the RBR and reaches the minimum when the RBR is 0.3. | Zhimin Zhang Hegao Wu Yang Wang Qiling Zhang Teng Li | 2017 | Transactions of Tianjin University2017，23，5： | 0 |
| 15 | Root Endophyte Shift and Key Genera Discovery in Rice under Barnyardgrass Stress显示文摘Despite increasing knowledge of barnyardgrass(Echinochloa crus-galli) interference with rice, relatively little is known how endophytes improve the ability of rice against barnyardgrass stress. Here, we provided a detailed temporal characterization of rice root-associated microbiomes during co-cultivation with barnyardgrass and a comparison with the microbiomes of weed-free rice plants. Alpha diversity analysis indicated that barnyardgrass had the opposite effects on endophytic bacteria and fungi in rice roots, in terms of the community diversity, richness and coverage at the rice seedling stage. Principal coordinate analysis showed that barnyardgrass had only a minor effect on the community composition of endophytes in rice roots at the rice seedling stage, but showed a significant and maximum interference at the heading stage. Rice recruited many endophytes to resist biotic stress from barnyardgrass, especially for fungi. PICRUSt(phylogenetic investigation of communities by reconstruction of unobserved states) predictive analysis indicated that 23 metabolic pathways of bacteria were overrepresented in rice. In addition, the main trophic mode of fungi was pathotroph according to FUNGuild analysis. A positive correlation between bacteria and fungi in rice roots was found via network analysis. Anaeromyxobacter, Azospira and Pseudolabrys were the vital bacteria, Phaeosphaeria and Funneliformis were the dominant fungi in maintaining the stability of the ecological network. These results provided data and a theoretical basis for the in-depth understanding of what role endophytes play in rice resistance to barnyardgrass stress and will have implications on improving the resistance of rice against biotic stress using root microbiota. | LI Shuyan YAN Qiling WANG Jieyu JIANG Huidan LI Zuren PENG Qiong | 2023 | Rice science2023，30，2： | 0 |
| 16 | Design and experimental verification of a monolithic complete-light modulator based on birefringent materials显示文摘This paper presents a method to design a monolithic complete-light modulator(MCLM) that fully controls the amplitude, phase, and polarization of incident light. The MCLM is made of birefringent materials that provide different refractive indices to orthogonal eigen-polarizations, the ordinary o and extraordinary e states. We propose an optimization method to calculate the two relief depth distributions for the two eigen-polarizations. Also, a merging algorithm is proposed to combine the two relief depth distributions into one. The corresponding simulations were carried out in this work and the desired light distribution, including information on amplitude,phase, and four polarization states, was obtained when a laser beam passed through a 16-depth-level microstructure whose feature size is 8 μm. The structure was fabricated by common photolithography. An experimental optical system was also set up to test the optical effects and performances of the MCLM. The experimental performance of the MCLM agrees with the simulation results, which verifies the validity of the algorithms we propose in this paper. | YINGFEI PANG AXIU CAO JIAZHOU WANG HUI PANG WEI YAN XIANGDONG WU LIFANG SHI QILING DENG | 2019 | Photonics Research2019，7，8： | 0 |
| 17 | Emerging chemical engineering of exosomes as“bioscaffolds”in diagnostics and therapeutics显示文摘All cells release extracellular vesicles(EVs)as part of their normal physiology.As one of the subtypes,exosomes(EXOs)have an average size range of approximately 40 nm e160 nm in diameter.Benefiting from their inherent immunogenicity and biocompatibility,the utility of autologous EXOs has the potential for both disease diagnosis/treatment.EXOs are generally employed as“bioscaffolds”and the whole diagnostic and therapeutic effects are mainly ascribed to exogenous cargos on the EXOs,such as proteins,nucleic acids,and chemotherapeutic agents and fluorophores delivered into specific cells or tissues.Surface en-gineering of EXOs for cargo loadings is one of the prerequisites for EXO-mediated diagnosis/treatment.After revisiting EXO-mediated diagnosis/treatment,the most popular strategies to directly undertake loadings of exogenous cargos on EXOs include genetic and chemical en-gineering.Generally,genetically-engineered EXOs can be merely produced by living organisms and intrinsically face some drawbacks.However,chemical methodologies for engineered EXOs diversify cargos and extend the functions of EXOs in the diagnosis/treatment.In this review,we would like to elucidate different chemical advances on the molecular level of EXOs along with the critical design required for diagnosis/treatment.Besides,the prospects of chemical engineering on the EXOs were critically addressed.Nevertheless,the superiority of EXO-medi-ated diagnosis/treatment via chemical engineering remains a challenge in clinical translation and trials.Furthermore,more chemical crosslinking on the EXOs is expected to be explored.Despite substantial claims in the literature,there is currently no review to exclusively summa-rize the chemical engineering to EXOs for diagnosis/treatment.We envision chemical engi-neering of EXOs will encourage more scientists to explore more novel technologies for a wider range of biomedical applications and accelerate the successful translation of EXO-based drug“bioscaffolds”from bench to bedside. | Jianwei Wang Meijiao Wang Ning Jiang Shijia Ding Qiling Peng Lei Zheng | 2023 | Genes & Diseases2023，10，4： | 0 |
| 18 | Microscopic Investigation of Ethylene Carbonate Interface: A Molecular Dynamics and Vibrational Spectroscopic Study显示文摘Ethylene carbonate(EC) liquid and its vapor-liquid interface were investigated using a combination of molecular dynamics(MD)simulation and vibrational IR, Raman and sum frequency generation(SFG)spectroscopies. The MD simulation was performed with a flexible and polarizable model of the EC molecule newly developed for the computation of vibrational spectra. The internal vibration of the model was described on the basis of the harmonic couplings of vibrational modes, including the anharmonicity and Fermi resonance coupling of C=O stretching. The polarizable model was represented by the charge response kernel(CRK),which is based on ab initio molecular orbital calculations and can be readily applied to other systems. The flexible and polarizable model can also accurately reproduce the structural and thermodynamic properties of EC liquid. Meanwhile, a comprehensive set of vibrational spectra of EC liquid, including the IR and Raman spectra of the bulk liquid as well as the SFG spectra of the liquid interface, were experimentally measured and reported. The set of experimental vibrational spectra provided valuable information for validating the model, and the MD simulation using the model comprehensively elucidates the observed vibrational IR, Raman, and SFG spectra of EC liquid. Further MD analysis of the interface region revealed that EC molecules tend to orientate themselves with the C=O bond parallel to the interface. The MD simulation explains the positive Im[χ^((2))](ssp) band of the C=O stretching region in the SFG spectrum in terms of the preferential orientation of EC molecules at the interface. This work also elucidates the distinct lineshapes of the C=O stretching band in the IR, Raman, and SFG spectra. The lineshapes of the C=O band are split by the Fermi resonance of the C=O fundamental and the overtone of skeletal stretching. The Fermi resonance of C=O stretching was fully analyzed using the empirical potential parameter shift analysis(EPSA) method. The apparently different lineshapes of the C=O stretching band in the IR, Raman, and SFG spectra were attributed to the frequency shift of the C=O fundamental in different solvation environments in the bulk liquid and at the interface. This work proposes a systematic procedure for investigating the interface structure and SFG spectra, including general modeling procedure based on ab initio calculations, validation of the model using available experimental data, and simultaneous analysis of molecular orientation and SFG spectra through MD trajectories. The proposed procedure provides microscopic information on the EC interface in this study, and can be further applied to investigate other interface systems, such as liquid-liquid and solid-liquid interfaces. | WANG Lin XIN Liang ISHIYAMA Tatsuya PENG Qiling YE Shen MORITA Akihiro | 2018 | 物理化学学报2018，34，10： | 0 |
| 19 | Sperm cryopreservation in the human sperm bank:11-year results of the Chinese mainland sperm banking network显示文摘To the Editor:Montegazza in 1866 was the first to suggest banks for frozen human semen.[1]In 1981,China's first human sperm bank was successfully established at the CITIC Xiangya Hospital.During the previous four decades,from 1981 to 2020,there were 27 human sperm banks in Chinese mainland.Human sperm banks provide cryopreservation of spermatozoa services for males needing to preserve fertility for an extended period in the Chinese mainland. | Xiao Liu Qiling Wang Wenbing Zhu Zhou Zhang Wenhao Tang Huiqiang Sheng Jigao Yang Yushan Li Xiaowei Liang Tianqing Meng Zhiqiang Wang Faxi Lin Hao Dong Xiaojin He Xianglong Jiang Shanjun Dai Aiping Zhang Chunying Song Zuowen Liang Feng Zhang Xiaojun Wang Peiyu Liang Guihua Gong Xiaohong Huai Fuping Xinzong Zhang | 2022 | Chinese Medical Journal2022，135，22： | 0 |
| 20 | Transcriptomic and metabolomic analysis provides insights into lignin biosynthesis and accumulation and differences in lodging resistance in hybrid wheat显示文摘The use of hybrid wheat is one way to improve the yield in the future.However,greater plant heights increase lodging risk to some extent.In this study,two hybrid combinations with differences in lodging resistance were used to analyze the stem-related traits during the filling stage,and to investigate the mechanism of the difference in lodging resistance by analyzing lignin synthesis of the basal second internode(BSI).The stem-related traits such as the breaking strength,stem pole substantial degree(SPSD),and rind penetration strength(RPS),as well as the lignin content of the lodging-resistant combination(LRC),were significantly higher than those of the lodgingsensitive combination(LSC).The phenylpropanoid biosynthesis pathway was significantly and simultaneously enriched according to the transcriptomics and metabolomics analysis at the later filling stage.A total of 35 critical regulatory genes involved in the phenylpropanoid pathway were identified.Moreover,42%of the identified genes were significantly and differentially expressed at the later grain-filling stage between the two combinations,among which more than 80%were strongly up-regulated at that stage in the LRC compared with LSC.On the contrary,the LRC displayed lower contents of lignin intermediate metabolites than the LSC.These results suggested that the key to the lodging resistance formation of LRC is largely the higher lignin synthesis at the later grain-filling stage.Finally,breeding strategies for synergistically improving plant height and lodging resistance of hybrid wheat were put forward by comparing the LRC with the conventional wheat applied in large areas. | Weibing Yang Shengquan Zhang Qiling Hou Jiangang Gao Hanxia Wang Xianchao Chen Xiangzheng Liao Fengting Zhang Changping Zhao Zhilie Qin | 2024 | Journal of Integrative Agriculture2024，23，4： | 0 |
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