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6篇 您的检索式:作者名="QINGLIN DENG"
    题名 作者 年代 出处 被引量
1Influence of white etching layer on rolling contact behavior at wheel-rail interface显示文摘The existence of narrow and brittle white etching layers(WELs)on the rail surface is often linked with the formation of rail defects such as squats and studs,which play the key roles in rail surface degradation and tribological performance.In the present study,a systematic investigation on stress/strain distribution and fatigue life of the WEL during wheel-rail rolling contact was conducted based on a numerical model considering the realistic wheel geometry.This is the first study considering the influence of rail materials,loading pressure,frictional condition,WEL geometry(a/b),and slip ratio(Sr)in the practical service conditions at the same time.The results revealed much higher residual stress in WEL than in rail matrix.Stress changes along the rail depth matched with the previously reported microstructure evolutions.The current work revealed that the maximum difference in contact stress between the wheel passages of rail matrix and the WEL region(noted as stress variation)rises with the increase of loading pressure,the value of a/b,and Sr;but drops with the friction coefficient(μ).In addition,a critical length–depth ratio of 5 for a/b has been found.The fatigue parameter,FP,of the WEL decreased quickly with the length–depth ratio when it was less than 5 and then increased slightly when it was larger than 5.This study also revealed that the fatigue life of the WEL was reduced for high strength head hardened(HH)rail compared with standard carbon(SC)rail.Qinglin LIAN Guanyu DENG Hongtao ZHU Huijun LI Xi WANG Zhiming LIU 2020Friction2020,8,6:4
2Stress corrosion cracking of a high-strength friction-stir-welded joint of an Al–Zn–Mg–Zr alloy containing 0.25wt.% Sc显示文摘Ying Deng Bing Peng Guofu Xu Qinglin Pan Rui Ye Yingjun Wang Liying Lu Zhimin Yin 2015Corrosion Science2015,,:1
3Integrin-Associated CD151 Drives ErbB2-Evoked Mammary Tumor Onset and Metastasis显示文摘Xinyu Deng Qinglin Li John Hoff Marian Novak Helen Yang Hongyan Jin Sonia F. Erfani Chandan Sharma Pengcheng Zhou Isaac Rabinovitz Arnoud Sonnenberg Yajun Yi Peter Zhou Christopher S. Stipp David M. Kaetzel Martin E. Hemler Xiuwei H. Yang 2012Neoplasia2012,,8:1
4Scalable synthesis of A_2S_3 (A=Sb, Bi) submicro/nanowires using their powders via solvothermal proceeding显示文摘Single-crystal A2S3 (A=Sb, Bi) nanowires were successfully prepared via using their powders as precursors by solvothermal proceeding. The reac-tion temperature and time as well as solvent strongly influence final A2S3 crystalline morphology and size. Experimental results show that Sb2S3 rods prepared in ethylene glycol are thicker than its wires with av-erage diameter of 400 nm prepared in the mixture solvent of ethylene glycol and ethylenediamine at 200 oC for 24 h. However, under the same reaction con-dition, uniform submicrowires of Bi2S3 with average diameter of 150 nm can be obtained. When reaction temperature is decreased to 150 oC and reaction time is 40 h, pure Sb2S3 wires cannot be prepared. The possible mechanism is briefly discussed for the transformation of the Sb2S3 powders to their wire-like crystals.JI Tianhao LIU Guanrao QI Xingyi YANG Qinglin DENG Yuan GUO Lin 2006Chinese Science Bulletin2006,51,6:1
5L-Selenocystine induce HepG2 cells apoptosis through ROS-mediated signaling pathways显示文摘At present,Hepatocarcinoma is one of the main causes of tumor related death all over the world.However,there are still many clinical restrictions on the treatment of liver cancer.Recently,L-Selenocystine has been shown to be a novel treatment for tumors,especially human glioma cells.But,the mechanism of L-Selenocystine against hepatocellular carcinoma remains unclear.Therefore,the main objective of this study was to investigate the effects of L-Selenocystine on HepG2 cell proliferation and activation of reactive oxygen species(ROS)mediated signaling pathway.L-Selenocystine can significantly inhibit HepG2 cell proliferation by activating caspase-3 and cleaving PARP to induce apoptosis.Moreover,the excessive production of ROS and the influence of Bax signaling pathway which can promote cell apoptosis are key factors for L-Selenocystine to induce HepG2 cell apoptosis.Therefore,the date of this study suggest that ROS mediated signal transduction mechanism may provide certain reference significance for L-Selenocystine induced HepG2 cell apoptosis.HAIYANG CHEN JINGYAO SU DANYANG CHEN YUYE DU RUILIN ZHENG QINGLIN DENG QIANQIAN DU BING ZHU YINGHUA LI 2022BIOCELL2022,46,10:0
6A parallel approach to direct resolution of albuterol显示文摘A library consisting of a series of O,O'-diaryzoyl-L-(-)-tartaric acids (2) was designed and synthesized. The substituent on the aromatic ring of 2 significantly affects the diastereomeric excess and efficiency of the resolution of racemic albuterol (1). Excel-lent resolving reagent 2a was selected for the resolution of rac-1 via the parallel approach. However,a family of three resolving reagents failed to improve the resolution efficiency of rac-1.ZHONG QingLin PENG XiaoHua WU TongFei FU FangMin CUI Xin ZHU Jin DENG JinGen 2010Chinese Science Bulletin2010,55,25:0
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