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44篇 您的检索式:作者名="Pumar"
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1sTWEAK is a marker of early haematoma growth and leukoaraiosis in intracerebral haemorrhage显示文摘Objective To study the association between early growth of haematoma with biomarkers of endothelial dysfunction such as leukoaraiosis(LA)and the soluble tumour necrosis factor-like weak inducer of apoptosis(sTWEAK)in patients with intracerebral haemorrhage(ICH).Methods This is a retrospective observational study of patients with nontraumatic ICH.Clinical and biochemical parameters were analysed.sTWEAK levels were measured by ELISA.LA was analysed in the hemisphere without haemorrhage to avoid interference with the acute injury.The main endpoint was the haematoma growth evaluated by the difference in volume between the second and the initial neuroimage.Poor functional outcome,defined as a modified Rankin Scale>2 at 3 months,was considered as secondary endpoint.Receiver operating characteristic curve analysis was performed to stablish the best cut-off for sTWEAK levels associated with haematoma growth.Results We included 653 patients with ICH in our analysis(71.1±11.9 years,44%women).Haematoma growth was observed in 188 patients(28.8%).sTWEAK levels≥5600 pg/mL predicted ICH growth with a sensitivity of 84%and a specificity of 87%.sTWEAK levels≥5600 pg/mL and the presence of LA were associated with haematoma growth(OR:42.46;(CI 95%22.67 to 79.52)and OR:2.73(CI 95%1.39 to 5.34),respectively).Also,the presence of LA(OR:4.31(CI 95%2.89 to 6.42))and the interaction between ICH growth and sTWEAK(OR:2.23(CI 95%1.40 to 3.55))were associated with poor functional outcome at 3 months.Conclusion sTWEAKs,together with the presence and grade of LA,are biomarkers able to predict ICH growth and poor functional outcome in patients with ICH.Andrés da Silva-Candal Iria López-Dequidt Manuel Rodriguez-Yañez PauloÁvila-Gómez JoséManuel Pumar JoséCastillo Tomás Sobrino Francisco Campos Ramón Iglesias-Rey Pablo Hervella 2021Stroke & Vascular Neurology2021,6,4:2
2Plasma Metalloproteinase-9 Concentration Predicts Hemorrhagic Transformation in Acute Ischemic Stroke显示文摘Mar Castellanos Rogelio Leira Joaquín Serena José M. Pumar Ignacio Lizasoain José Castillo Antoni Dávalos 2003Stroke: Journal of the American Heart Association2003,,1:2
3Body temperature and fi brinogen are related to early neurological deterioration in acute isehe mie stroke显示文摘Davalos A Castillo J Pumar JM 1997Cerebrovasc Dis1997,7,:1
4Optimised low-dose multidetector CT protocol for children with cranial deformity 显示文摘Vazquez JL Pombar MA Pumar JM 2013Eur J Radiol2013,23,8:1
5Areas of hyperdensity following a mechanical intraarterial thrombectomy in acute ischaemic stroke显示文摘Pumar JM Banguero A Masso A 2014Rev Neurol2014,59,2:1
6Oblique multiplanar re- formation in muhisliee temporal bone CT 显示文摘Ulla MB VClzquez F Pumar JM 2009Surgical & Radio- logic Anatomy2009,31,6:1
7Zooming of Terrain Imagery Using Fractal-based Interpolation 显示文摘Pumar M A 1996Computer & Graphics1996,20,1:1
8High plasma glutamate concentrations are associated with infarct growth in acute ischemic stroke显示文摘M Castellanos T Sobrino S Pedraza O Moldes J M. Pumar Y Silva J Serena M García-Gil J Castillo A Dávalos 2008Neurology2008,,23:1
9LEO stent monotherapy for the endovascular reconstruction of fusiform aneurysms of the middle cerebral artery 显示文摘PUMAR J M LETE I PARDO M I 2008Am J Neuroradiol2008,29,9:1
10Relationships of apolipoprotein B(100) with the metabolic syndrome in type 2 diabetes mellitus显示文摘 Losada F Pumar A 2002Diabetes Res Clin Pract2002,57,3:1
11Anxiety and depression- Important psychological eomorbidities of COPD 显示文摘Pumar MI Gray CR Walsh JR 2014J Thorac Dis2014,6,11:1
12Early hyponatraemia after pituitary surgery: cerebral salt-wasting syndrome 显示文摘Guerrero R Pumar A Soto A 2007Eur J Endocrinol2007,156,6:1
13Preliminary experience with LEO self-expanding stent for the treatment of intracranial aneurysms显示文摘 Miguel Blanco Fernando Vázquez 2005American Journal of Neuroradiology2005,26,:1
14Preoperative serum CA15-3 and CEA levels and clinical-biological parameters in breast tumors 显示文摘Ruibal A Garrido Pumar M Arias JI 2006Rev Esp Med Nuel2006,25,3:1
15Areas of hyperdensity fol- lowing a mechanical intraarterial thrombectomy in acute is- chaemic stroke显示文摘Pumar J M Banguero A Masso A 2014Rev Neurol2014,59,2:1
16Anxiety and depression-important psychological comorbidities of COPD显示文摘Pumar MI Gray CR Walsh JR 2014J Thorac Dis2014,6,11:1
17High plasma glutamate concentrations are associated with infarct growth in acute ischemic stroke显示文摘M Castellanos T Sobrino S Pedraza O Moldes J M. Pumar Y Silva J Serena M García-Gil J Castillo A Dávalos 2008Neurology2008,,23:1
18Relationship of C-peptide levels and C-peptide/bloodsugar ratio with clinical/biochemical variables associated with insulin resistance in orally-treated, well-con-trolled type 2 diabetic patients 显示文摘Relimpio F Losada F Pumar A 1997Diabeties Res Clin Pract1997,36,3:1
19Zooming of terrain imagery using fractal-based interpolation显示文摘Pumar M A 1996Computation and Graphics1996,20,1:1
20Preliminary experience with LEO self-expanding stent for the treatment of intracranial aneurysms显示文摘Pumar JM Blanco M Vazquez F 2005American Journal of Neuroradiology2005,26,10:1
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