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| 1 | IL-1 β genesis: the art of regulating the regulator显示文摘In a study published in Cellular and Molecular Immunology,Singh et al.demonstrated a new mechanism of monocyte IL-1βproduction.1 It was observed that TLR-4-and TLR-2-induced IRAK-ERK pathway cross-talk with p67phox-Nox-2 for reactive oxygen species(ROS)generation,thus regulating IL-1βtranscription and processing in monocytes.This study not only establishes a direct link between IRAK and ERK,but also demonstrates the regulation of p67phox-Nox-2 by ERK for ROS and IL-1βproduction(Fig.1).This study shows that the IRAK-ERK axis can regulate both IL-βtranscription and processing through ROS. | Priya Gupta Manoj K.Barthwal | 2018 | Cellular & Molecular Immunology2018，15，11： | 4 |
| 2 | Effect of bioflocculants on the coagulation activity of alum for removal of trihalomethane precursors from low turbid water显示文摘Reactivity of chlorine towards hydrophobic groups present in natural organic matter(NOM)provokes the formation of carcinogenic disinfection byproducts such as trihalomethanes in chlorinated water. The present study aimed to investigate the variations in coagulant activity of alum using two different bioflocculants(coagulant aid) namely, Moringa oleifera and Cyamopsis tetragonoloba for the removal of hydrophobic fractions of NOM and subsequent chlorine consumption by treated water. Effect of dual coagulants on trihalomethane surrogate parameters such as total organic carbon, dissolved organic carbon, UV absorbing materials and prominent hydrophobic species such as phenolic groups along with aromatic chromophores, polyhydroxy aromatic moiety have also been studied. The concept of differential spectroscopy and absorbance slope index has been employed to understand the combined effects of alum-bioflocculants on the reactivity of NOM with chlorine. Our result shows that the combination of alum and C. tetragonoloba is more efficient for reducing trihalomethane surrogates from chlorinated water as compared to M. oleifera. C. tetragonoloba elicited synchronized effects of sweep coagulation and particle bridging-adsorption which eventually facilitated efficient removal of hydrophobic fractions of NOM. The variation in the mechanistic approach of bioflocculants was due to the presence of cationic charge on M. oleifera and adhesive property of C. tetragonoloba. | Tanwi Priya Abhrajyoti Tarafdar Bramha Gupta Brijesh Kumar Mishra | 2018 | Journal of Environmental Sciences2018，30，8： | 2 |
| 3 | Pathophysiology of alcoholic pancreatitis:An overview显示文摘Use of alcohol is a worldwide habit regardless of socio- economic background. Heavy alcohol consumption is a potential risk factor for induction of pancreatitis. The current review cites the updated literature on the alcohol metabolism, its effects on gastrointestinal and pancreatic function and in causing pancreatic injury, genetic predisposition of alcohol induced pancreatitis. Reports describing prospective mechanisms of action of alcohol activating the signal transduction pathways, induction of oxidative stress parameters through the development of animal models are being presented. | Parimal Chowdhury Priya Gupta | 2006 | World Journal of Gastroenterology2006，12，46： | 2 |
| 4 | Characterization of mechanical and electrical properties of epoxy-glass microballoon syntactic composites显示文摘 | GUPTA N PRIYA S ISLAM R | 2006 | Ferroelectrics2006，345，1： | 1 |
| 5 | Effect of Simultaneous Exposure to Lead and Cadmium on Gonadotropin Binding and Steroidogenesis on Granulosa Cells:An in Vitro Study显示文摘 | Priya P N Pillai A Gupta S | 2004 | Indian J Exp Bio12004，42，2： | 1 |
| 6 | Microbial keratinases and their prospective applications: an overview显示文摘 | Rani Gupta Priya Ramnani | 2006 | Applied Microbiology and Biotechnology2006，，1： | 1 |
| 7 | Characterization of Mechanical and Electrical Properties of Epoxy-glass Microballoon Syntactic Composites显示文摘 | Gupta N Priya S Ricci R I W | 2006 | Ferroelectrics2006，345，1： | 1 |
| 8 | Effects of combined exposure to lead and cadmium on the hypothalamic-pituitary axis function in proestrous rats显示文摘 | Pillai A Priya L Gupta S | 2003 | Food Chem Toxicol2003，41，： | 1 |
| 9 | Effect of combined exposure to lead and cadmium on the hypothalamic-pituitary axis function in prostrous rats显示文摘 | Pillai A Priya L Gupta S | 2003 | Food and Chemical Toxicology2003，41，： | 1 |
| 10 | Effeets of combined exposure to lead and cadmium on the hypothalamic-pituitary axis function in proestrous rats显示文摘 | PILLAI A PRIYA L GUPTA S | 2003 | Food Chem Toxicol2003，41，3： | 1 |
| 11 | Microbial keratinases and their prospective applications: an overview显示文摘 | Rani Gupta Priya Ramnani | 2006 | Applied Microbiology and Biotechnology2006，，1： | 1 |
| 12 | Optimization of medium composition for keratinase production on feather by Bacillus licheniformis RG1 using statistical methods involving response surface methodology显示文摘 | Ramnani Priya Gupta Rani | 2004 | Biotechnol Appl Biochem2004，40，： | 1 |
| 13 | Effect of simultaneous exposure to lead and cadmium on gonadotropin binding and steroidiogenesis on granulose cells:an in vitro study 显示文摘 | Priya PN Pillai A Gupta S | 2004 | Idian J Exp Bid2004，42，2： | 1 |
| 14 | Effects of combined exposure to lead and cadmium on the hypothalamic - pituitary axis function in proestrous rats显示文摘 | PILLAI A PRIYA L GUPTA S | 2003 | Food Chem Toxico12003，41，3： | 1 |
| 15 | Characterization of 4-methyl-2-oxo-1,2-dihydro-quinolin-6-yl acetate as an effective antiplatelet agent显示文摘 | PRIYA N GUPTA A CHAND K | 2010 | Bioorgan & Med Chem2010，18，： | 1 |
| 16 | Effects of combined exposure to lead and cadmium on the hypothalamic-pituitary axis function in proestrous rats显示文摘 | Pillai A Priya L Gupta S | 2003 | Food Chem Toxicol2003，41，： | 1 |
| 17 | Effect of simultaneous exposure to lead and cadmium on gonadotropin binding and steroidiogenesis on granulose cells:an in vitro study显示文摘 | PRIYA P N PILLAI A GUPTA S | 2004 | Indian J Exp Biol2004，42，2： | 1 |
| 18 | 基于质量源于设计理念研究不同地区余甘子的关键性状显示文摘目的探讨质量源于设计(QbD)工具在评估印度5个不同地区余甘子地理变异中的应用。方法在本实验中,采用简化四次模型的Box-Behnken设计,运行105次,结合使用Design Expert软件进行随机响应面映射。本研究使用了三种不同的浸提方法(索氏浸提、浸渍浸提和超声浸提)以及三种溶剂[蒸馏水、甲醇和水-甲醇混合物(50:50 v/v)]。采用气相色谱-质谱法(GC-MS)测定并分析余甘子的抗氧化活性、总黄酮含量(TFC)和总酚含量(TPC),以鉴定其主要成分。结果QbD叠加图显示余甘子的提取值不低于30%w/w,2,2-二苯基-1-三硝基苯肼(DPPH)不低于60%mcg/mL(微克每毫升),TFC不低于75 mg QE/g(毫克槲皮素当量每克干原料),TPC不低于80 mg GAE/g(毫克没食子酸当量每克干原料)。此外,(GC-MS)数据证实了余甘子的生物活性存在变异。结论本研究模型能较好的描述浸提值、DPPH、TFC和TPC的变化。QbD方法可能倾向于在浸提过程中优先考虑彻底性,最终提高浸提产品的质量。 | Grishm Rohilla Priya Masand Pooja Dhama Anurag Sunil Gupta Alok Sharma | 2023 | Digital Chinese Medicine2023，6，3： | 0 |
| 19 | Delineating the role of phytocompounds against anti-bacterial drug resistance–An update显示文摘Antibacterial resistance developed by bacteria due to the unlimited use of antibiotics has posed a challenge for human civilization.This kind of problem is not limited to India only,but it is a global concern.Nowadays,many treatments and medicines for bacterial diseases have been developed.However,they possess some drawbacks.Therefore,the alternative medicine has been used to target the drug resistant mechanisms and such medicines have less side effects which is becoming necessary.Natural products have traditionally or historically been of importance for the development of antibacterial agents and are also known to overcome bacterial drug resistance by directly targeting the drug resistance mechanisms in bacteria.In recent years,researchers have also focused on new drug discovery from plant-based research.They have looked on various phytocompounds as antibacterial agents.In the current review,we report various classes of secondary metabolites such as phenolic compounds,flavonoids,alkaloids,saponins,terpenes,quinones,and some essential oils that have been used as an antibacterial agent.In addition,we also discuss several mechanisms behind bacterial multi-drug resistance that are used during bacterial pathogenesis. | REKHA GAHTORI MOSLEH MOHAMMAD ABOMUGHAID NIDHI NEGI SARAVANAN KRISHNAN SUGAPRIYA DHANASEKARAN SOUMYA PANDIT KANU PRIYA DILLIP KUMAR BISHI RAM PRASAD PIYUSH KUMAR GUPTA | 2021 | BIOCELL2021，45，6： | 0 |
| 20 | Multidetector computed tomography imaging of congenital anomalies of major airways:A pictorial essay显示文摘Congenital airway anomalies can be asymptomatic or may cause severe respiratory distress requiring immediate treatment.These anomalies can present early in life,or may be just incidental findings.It is important to recognize these entities to realize their clinical significance and to avoid false diagnosis.In this article, the various congenital airway anomalies and their imaging features by multidetector computed tomography (MDCT)are reviewed in order of occurrence during the embryological timeline.This pictorial essay reviews the various distinct congenital airway lesions and their MDCT manifestations.It also provides insight into the embryological basis of the congenital airway lesions encountered. | Dinesh Kumar Sundarakumar Ashu Seith Bhalla Raju Sharma Arun Kumar Gupta Susheel Kumar Kabra Priya Jagia | 2011 | World Journal of Radiology2011，3，12： | 0 |
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