|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Approaches to functional genomics in filamentous fungi显示文摘在细丝状的真菌的基因功能的学习是在很最近的年里做了大进展的研究的一个领域。很多转变和基因操作策略被开发了并且适用于经济地重要的细丝状的真菌和 oomycetes 的一张多样、很快膨胀的表。与真菌的染色体的重要数字,定序的现在或被定序的、功能的基因组学答应揭开来年里的很多新信息。这评论讨论在在细丝状的真菌检验基因功能被做了并且描述不同途径的优点和限制的最近的进展。 | Richard J Weld Kim M Plummer Margaret A Carpenter Hayley J Ridgway | 2006 | Cell Research2006，16，1： | 19 |
| 2 | 水-岩相互作用地球化学模型的回顾与展望显示文摘从地球化学模型开始起步以来,将化学热力学应用于地球化学系统已经历了30年的历程.人们利用热力学模型开发了一系列计算机程序,在大范围内进行了温度、压力和成分的地球化学作用的研究。经过演化,地球化学模型有两类;即“反演模型”和“正演模型”,前者用水和岩石成分确定和定量研究地球化学反应,后者则用假想的地球化学反应预测水和岩石的化学成分.由于缺乏水文学、矿物学、反应动力学以及地下水系统中反应物与生成物的化学、同位素成分等资料,在地下水环境中应用地球化学模型遇到了严竣的挑战。今后,地球化学模型的重大进展,是在非均质系统中结合实际,应用化学动力学,更进一步地使流体运动与反应模型结合起来. | L.Niel Plummer 周文斌 | 1993 | 华东地质学院学报1993，16，2： | 17 |
| 3 | No association between cyclooxygenase-2 and uridine diphosphate glucuronosyltransferase 1A6 genetic polymorphisms and colon cancer risk显示文摘AIM:To investigate the association of variations in the cyclooxygenase-2(COX2) and uridine diphosphate glucuronosyltransferase 1A6(UGT1A6) genes and non-steroidal anti-inflammatory drugs(NSAIDs) use with risk of colon cancer.METHODS:NSAIDs,which are known to reduce the risk of colon cancer,act directly on COX2 and reduce its activity.Epidemiological studies have associated variations in the COX2 gene with colon cancer risk,but others were unable to replicate this finding.Similarly,enzymes in the UGT1A6 gene have been demonstrated to modify the therapeutic effect of NSAIDs on colon adenomas.Polymorphisms in the UGT1A6 gene have been statistically shown to interact with NSAID intake to influence risk of developing colon adenomas,but not colon cancer.Here we examined the association of tagging single nucleotide polymorphisms(SNPs) in the COX2 and UGT1A6 genes,and their interaction with NSAID consumption,on risk of colon cancer in a population of 422 colon cancer cases and 481 population controls.RESULTS:No SNP in either gene was individually statistically significantly associated with colon cancer,nor did they statistically significantly change the protective effect of NSAID consumption in our sample.Like others,we were unable to replicate the association of variants in the COX2 gene with colon cancer risk(P > 0.05),and we did not observe that these variants modify the protective effect of NSAIDs(P > 0.05).We were able to confirm the lack of association of variants in UGT1A6 with colon cancer risk,although further studies will have to be conducted to confirm the association of these variants with colon adenomas.CONCLUSION:Our study does not support a role of COX2 and UGT1A6 genetic variations in the development of colon cancer. | Cheryl L Thompson Sarah J Plummer Alona Merkulova Iona Cheng Thomas C Tucker Graham Casey Li Li | 2009 | World Journal of Gastroenterology2009，15，18： | 11 |
| 4 | Digital switched hydraulics显示文摘 | Min PAN Andrew PLUMMER | 2018 | Frontiers of Mechanical Engineering2018，13，2： | 11 |
| 5 | Comparative analysis of open and laparoscopic colectomy for malignancy in a developing country显示文摘AIM: To compare the short-term, including oncologic, outcomes of open vs laparoscopic colectomy for cancer in a developing country. METHODS: The records of patients who underwent elective open and laparoscopic colectomies for cancer at the University Hospital of the West Indies between January 2005 and December 2010 were retrospectively reviewed. Demographic(age, gender, Charlson comorbidity index score), peri-operative, post-operative and oncologic data were collected for each patient. Specific oncologic variables included lymph node yield, pathologic stage, grade, proximal, distal and circumferential margin involvement. Fisher's exact, Mann-Whitney, and binary logistic regression tests were used for analysis. Significance level was set atP < 0.05. RESULTS: There were 87 cases for open colectomy(OC) and 17 cases for laparoscopic colectomy(LC). Demographics did not significantly differ between OC and LC groups. Intra-operative blood loss and postoperative analgesic requirements did not significantly differ between groups. There was a trend towards longer operating times in OC group and shorter hospital stay in the LC group. Lymph node yield(14 vs 14, P = 0.619), proximal(10 cm vs 7 cm, P = 0.353) and distal(8 cm vs 8 cm, P = 0.57) resection margin distance and circumferential margin involvement(9 vs 0, P = 0.348) did not significantly differ between groups. Thirty-day morbidity was equivalent between groups(22 vs 6, P = 0.774). There were 6 deaths within 30 d of initial procedure, all in the OC group(6.9%). CONCLUSION: Laparoscopic colectomy in a developing country is oncologically safe and represents a option for colonic malignancies in these regions. Such data encourage the continued laparoscopic development. | Pierre-Anthony Leake Kristen Pitzul Patrick O Roberts Joseph M Plummer | 2013 | World Journal of Gastrointestinal Surgery2013，5，11： | 8 |
| 6 | 澳大利亚老年护理综合评估体系介绍及其对我国养老服务的启示显示文摘介绍澳大利亚老年护理综合评估体系的形成背景、内容与特点,总结澳大利亚老年护理综合评估体系对我国养老服务的启示,以期为我国养老服务体系的构建和完善提供借鉴。 | 李绵利 Virginia Plummer Jacqui Allen 庞书勤 | 2021 | 护理研究2021，35，14： | 7 |
| 7 | 失独者抑郁的心理弹性多因素作用模型显示文摘目的:中国失独家庭已多达百万个,65.6%的失独者存在严重而持久的抑郁情绪,需要及时干预。本研究旨在探索心理弹性与其影响因素的交互作用,比较心理弹性及其影响因素对于失独者抑郁的效应。方法:采用Connor-Davidson心理弹性量表、Zung抑郁自评量表、简易应对方式问卷、艾森克简式量表中国版、社会支持评定量表、一般自我效能感量表对长沙市9个行政区域212名失独者进行入户调查。基于Kumpfer心理弹性框架和心理应激多因素作用过程的理论模式构建假设模型并进行验证。结果:心理弹性的影响因素有:积极应对(总效应值为0.480)、支持利用(总效应值为0.359)、精神质(总效应值为-0.326)、消极应对(总效应值为0.279)、内外倾(总效应值为0.219)、客观支持(总效应值为0.077)。心理弹性对抑郁的影响以直接效应为主(总效应值为-0.344,占67.1%),也通过自我效能感发挥间接效应(总效应值为-0.169),心理弹性的总效应值占所有变量总效应的20.1%。结论:心理弹性受到人格、积极应对、社会支持等应激中介变量的直接和间接作用;心理弹性对抑郁主要产生直接负性效应,是定位于自我效能感之前的重要应激中介变量。个体-环境互动作用过程对心理弹性的影响较大,人格和支持利用通过影响消极应对、积极应对进而间接影响心理弹性。提高心理弹性应当关注个体-环境作用过程,即利用支持、积极应对、适当的消极应对,进而影响个体对自我的积极评价,这将是开发心理弹性干预方案以改善失独者抑郁的重要内容。 | 王安妮 张雯 郭玉芳 Wendy Cross Virginia Plummer Louisa Lam 张静平 | 2021 | 中南大学学报(医学版)2021，46，1： | 7 |
| 8 | Gastric Cancer显示文摘 | Catherine de Martel David Forman Martyn Plummer | 2013 | Gastroenterology Clinics of North America2013，，2： | 7 |
| 9 | Recent advances in the management of rectal cancer: No surgery, minimal surgery or minimally invasive surgery显示文摘Over the last decade,with the acceptance of the need for improvements in the outcome of patients affected with rectal cancer,there has been a significant increase in the literature regarding treatment options available to patients affected by this disease.That treatment related decisions should be made at a high volume multidisciplinary tumor board,after pre-operative rectal magnetic resonance imaging and the importance of total mesorectal excision(TME)are accepted standard of care.More controversial is the emerging role for watchful waiting rather than radical surgery in complete pathologic responders,which may be appropriate in 20%of patients.Patients with early T1 rectal cancers and favorable pathologic features can be cured with local excision only,with transanal minimal invasive surgery(TAMIS)because of its versatility and almost universal availability of the necessary equipment and skillset in the average laparoscopic surgeon,emerging as the leading option.Recent trials have raised concerns about the oncologic outcomes of the standard'top-down'TME hence transanal TME(Ta TME'bottom-up')approach has gained popularity as an alternative.The challenges are many,with a dearth of evidence of the oncologic superiority in the long-term for any given option.However,this review highlights recent advances in the role of chemoradiation only for complete pathologic responders,TAMIS for highly selected early rectal cancer patients and Ta TME as options to improve cure rates whilst maintaining quality of life in these patients,while we await the results of further definitive trials being currently conducted. | Joseph M Plummer Pierre-Anthony Leake Matthew R Albert | 2017 | World Journal of Gastrointestinal Surgery2017，9，6： | 6 |
| 10 | Global burden of cancers attributable to infections in 2008: a review and synthetic analysis显示文摘 | Catherine de Martel Jacques Ferlay Silvia Franceschi Jér?me Vignat Freddie Bray David Forman Martyn Plummer | 2012 | Lancet Oncology2012，，6： | 3 |
| 11 | T cell immune responses to SARS-CoV-2 and variants of concern(Alpha and Delta)in infected and vaccinated individuals显示文摘Our understanding of immune responses to SARS-CoV-2 and variants of concern(VOCs)has been primarily acquired through analysis of Spike-specific IgG responses.However,a more comprehensive understanding of the breadth and longevity of immune responses after infection and vaccination requires analysis of cellular immunity.Herein,we report on T cell immunity in infected and vaccinated individuals,identifying CD4+/CD8+T cell cytokine responses to SARS-CoV-2 and variant peptides(Alpha,B.1.1.7 and Delta,B.1.617.2). | Stanley C.Jordan Bong-Ha Shin Terry-Ann M.Gadsden Maggie Chu Anna Petrosyan Catherine N.Le Rachel Zabner Jillian Oft Isabel Pedraza Susan Cheng Ashley Vo Noriko Ammerman Jasmine Plummer Shili Ge Max Froch Anders Berg Mieko Toyoda Ruan Zhang | 2021 | Cellular & Molecular Immunology2021，18，11： | 3 |
| 12 | No association between phosphatase and tensin homolog genetic polymorphisms and colon cancer显示文摘AIM: To investigate the association between single nucleotide polymorphisms (SNPs) in the phosphatase and tensin homolog (PTEN) tumor suppressor gene and risk of colon cancer. METHODS: We utilized a population-based casecontrol study of incident colon cancer individuals (n= 421) and controls (n = 483) aged ≥ 30 years to conduct a comprehensive tagSNP association analysis of the PTEN gene. RESULTS: None of the PTEN SNPs were statistically significantly associated with colon cancer when controlled for age, gender, and race, or when additionally adjusted for other known risk factors (P > 0.05). Haplotype analyses similarly showed no association between the PTEN gene and colon cancer. CONCLUSION: Our study does not support PTEN as a colon cancer susceptibility gene. | Lynette S Phillips Cheryl L Thompson Alona Merkulova Sarah J Plummer Thomas C Tucker Graham Case Li Li | 2009 | World Journal of Gastroenterology2009，15，30： | 2 |
| 13 | Global Burden of Human Papillomavirus and Related Diseases显示文摘 | David Forman Catherine de Martel Charles J. Lacey Isabelle Soerjomataram Joannie Lortet-Tieulent Laia Bruni Jerome Vignat Jacques Ferlay Freddie Bray Martyn Plummer Silvia Franceschi | 2012 | Vaccine2012，，： | 2 |
| 14 | Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging显示文摘 | M. Leach B. Morgan P. Tofts D. Buckley W. Huang M. Horsfield T. Chenevert D. Collins A. Jackson D. Lomas B. Whitcher L. Clarke R. Plummer I. Judson R. Jones R. Alonzi T. Brunner D. Koh P. Murphy J. Waterton G. Parker M. Graves T. Scheenen T. Redpath M. Or | 2012 | European Radiology2012，，7： | 2 |
| 15 | An electro-hydrostatic actuator for hybrid active-passive vibration isolation显示文摘 | Jean-Paul Henderson Andrew Plummer Nigel Johnston | 2018 | International Journal of Hydromechatronics2018，1，1： | 2 |
| 16 | Changes in Climate Extremes Over the Australian Region and New Zealand During the Twentieth Century显示文摘 | Neil Plummer M. James Salinger Neville Nicholls Ramasamy Suppiah Kevin J. Hennessy Robert M. Leighton Blair Trewin Cher M. Page Janice M. Lough | 1999 | Climatic Change1999，，1： | 2 |
| 17 | Influence of β nucleation on the mechanical properties of isotactic polypropylene and rubber modified isotactic polypropylene 显示文摘 | Grein C Plummer C J G Kausch H H | 2002 | J Polymer2002，43，： | 1 |
| 18 | Twentieth century trends in climate extremes over the Australian region and New Zealand 显示文摘 | Plummer N Salinger M J Nicholls N | 1999 | Climatic Change1999，42，1： | 1 |
| 19 | Phase separation in epoxy resin-reactive dendritic hyperbranched polymer blends显示文摘 | PLUMMER C J G MEZZENGA R BOOGH L | 2001 | Polymer Engineering and Science2001，41，： | 1 |
| 20 | Human papillomavirus types in invasive cervical cancer worldwide: a meta-analysis显示文摘 | Clifford G M Smith J S Plummer M | 2003 | Br J Cancer2003，88，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员