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| 1 | Prognostic evaluation of postoperative adjuvant therapy for operable cervical cancer:10 years'experience of National Cancer Center in China显示文摘Objective: The aim of this study was to investigate the prognostic factors and to evaluate the impact of adjuvant therapy on clinical outcome for early-stage cervical cancer.Methods: The clinical-pathological data of all 1,335 patients with the International Federation of Gynecology and Obstetrics(FIGO) Ib–IIa cervical cancer treated with primary radical surgery at the Chinese National Cancer Center between May 2007 and Dec 2013 were retrospectively reviewed.The median follow-up was 70 months.Results: Of all the patients,61.6% of the cases received adjuvant therapy,with 5-year disease-free survival(DFS)of 92.1% and 5-year overall survival(OS) of 95.0%.In multivariate analysis,differentiation of G3(P<0.05),lymph node metastasis(LNM,P<0.05) and lymphovascular space invasion(LVSI,P<0.05) were independent predictors for OS,while LNM(P<0.05),deep stroma invasion(DSI,P<0.05) and LVSI(P<0.05) were independent factors for DFS.The samples were stratified by histologic type,and cervical squamous cell carcinoma(SCC) was found to share the same independent factors except for differentiation of OS.As to patients with cervical adenocarcinoma/adenosquamous carcinoma(AC/ASC),differentiation was the independent predictor of OS(P<0.05); and LVSI of DFS(P<0.05).Of 236 patients with high-risk factors,there was no significant difference in survival between concurrent chemoradiotherapy(CCRT,n=195),radiotherapy(RT,n=24),and chemotherapy(CT,n=17).Among the 190 patients with LNM who underwent CCRT,124 cases showed improved DFS after sequential CT(P=0.118),with a recurrence rate decrease of 14%,though the difference was not statistically significant.Patients with single intermediate-risk factors like DSI or LVSI were found to partially benefit from adjuvant therapy,but the difference was not statistically significant.Conclusions: LNM,LVSI,DSI and differentiation were found to be independent prognostic factors for operable cervical cancer.Aggressive postoperative adjuvant therapy based on single risk factors in Chinese National Cancer Center could benefit survival.CCRT+CT outperformed CCRT in high-risk patients.For patients with single non-high-risk factor,the role of adjuvant therapy needs to be further discussed. | Tong Shu Dan Zhao Bin Li Yating Wang Shuanghuan Liu Pingping Li Jing Zuo Ping Ba i RongZhang Lingying Wu | 2017 | Chinese Journal of Cancer Research2017，29，6： | 12 |
| 2 | Efficient Image Transmission Schemes over Zigbee-Based Image Sensor Networks显示文摘Image transmission is one of the biggest challenges in wireless sensor networks because of the limited resource on sensor nodes. We proposed two image transmission schemes driven by reliability and real time considerations in order to transfer JPEG images over Zigbee-based sensor networks. By adding two bytes counter in the header of data packet, we can easily solve the repeated data reception problem caused by retransmission mechanism in traditional Zigbees network layer. We proposed an efficient retransmission and acknowledgment mechanism in Zigbees application layer. By classifying different data reception response events, we can provide data packets with differential responses and ensure that image packets can be transferred quickly even with large maximum number of retransmission. Practical results show the effectiveness of our solutions to make image transmission over Zigbee-based sensor networks efficient. | TAO Dan YANG Guangwei CHEN Houjin WU Hao LIU Pingping | 2016 | Chinese Journal of Electronics2016，25，2： | 5 |
| 3 | DEAP1 encodes a fasciclin-like arabinogalactan protein required for male fertility in rice显示文摘Arabinogalactan proteins(AGPs)are widely distributed in plant cells.Fasciclin-like AGPs(FLAs)belong to a subclass of AGPs that play important roles in plant growth and development.However,little is known about the biological functions of rice FLA.Herein,we report the identification of a male-sterile mutant of DEFECTIVE EXINE AND APERTURE PATTERNING1(DEAP1)in rice.The deap1 mutant anthers produced aberrant pollen grains with defective exine formation and a flattened aperture annulus and exhibited slightly delayed tapetum degradation.DEAP1 encodes a plasma membrane-associated member of groupⅢplant FLAs and is specifically and temporally expressed in reproductive cells and the tapetum layer during male development.Gene expression studies revealed reduced transcript accumulation of genes related to exine formation,aperture patterning,and tapetum development in deap1 mutants.Moreover,DEAP1 may interact with two rice D6 PROTEIN KINASE-LIKE3 s(OsD6PKL3s),homologs of a known Arabidopsis aperture protein,to affect rice pollen aperture development.Our findings suggested that DEAP1 is involved in male reproductive development and may affect exine formation and aperture patterning,thereby providing new insights into the molecular functions of plant FLAs in male fertility. | Dan Zhou Ting Zou Kaixuan Zhang Pingping Xiong Fuxing Zhou Hao Chen Gongwen Li Kaiyou Zheng Yuhao Han Kun Peng Xu Zhang Shangyu Yang Qiming Deng Shiquan Wang Jun Zhu Yueyang Liang Changhui Sun Xiumei Yu Huainian Liu Lingxia Wang Ping Li Shuangcheng Li | 2022 | Journal of Integrative Plant Biology2022，64，7： | 2 |
| 4 | A new model for embryoimplantation:coculture of blastocysts and Ishikawa cells显示文摘 | Dan Zhang Pingping Lv Hefeng Huang | 2011 | Gyneco- logical Endocrinology2011，28，4： | 1 |
| 5 | Complete Manifolds with Harmonic Curvature and Finite L^p-Norm Curvature显示文摘Let(M^n, g)(n ≥ 3) be an n-dimensional complete Riemannian manifold with harmonic curvature and positive Yamabe constant. Denote by R and R?m the scalar curvature and the trace-free Riemannian curvature tensor of M, respectively. The main result of this paper states that R?m goes to zero uniformly at infinity if for p ≥ n, the L^p-norm of R?m is finite.As applications, we prove that(M^n, g) is compact if the L^p-norm of R?m is finite and R is positive, and(M^n, g) is scalar flat if(M^n, g) is a complete noncompact manifold with nonnegative scalar curvature and finite L^p-norm of R?m. We prove that(M^n, g) is isometric to a spherical space form if for p ≥n/2, the L^p-norm of R?m is sufficiently small and R is positive.In particular, we prove that(M^n, g) is isometric to a spherical space form if for p ≥ n, R is positive and the L^p-norm of R?m is pinched in [0, C), where C is an explicit positive constant depending only on n, p, R and the Yamabe constant. | Haiping FU Pingping DAN Shulin SONG | 2017 | Journal of Mathematical Research with Applications2017，37，3： | 0 |
| 6 | Variations of DON Content in Grain during Wheat Tempering at Different Temperatures显示文摘[Objective] The aim of this study was to observe variations of DON content in grain of two wheat cultivars during tempering at different temperatures, and explore the possible causes of the variations. [Method] Two naturally Fusarium-infested wheat samples Youmai 3 and Yangmai 14 were selected as experimental materials. Tempering was carried out at different temperature(15, 25 and 35 ℃) for 48 h. During tempering, wheat grain samples were collected every 8 h. DON contents in tempered grain were measured by HPLC coupled with UV detector. [Result] For Youmai 3, DON contents were in the ranges of 3.94-12.49, 4.26-6.11 and 3.41-7.91 μg/g during tempering at 15, 25 and 35 ℃, respectively. The highest DON contents were observed at the 32ndhour at 15 ℃, the 8thhour at 25 ℃ and the 32ndhour at 35 ℃, respectively. After tempering for 48 h, DON contents in grain were increased by 175.1%, 27.5% and 7.2%, respectively. For Yangmai 14, DON contents were in the ranges of 0.55-1.56, 0.39-0.77 and 0.57-3.17 μg/g during tempering at 15, 25 and 35 ℃, respectively. The highest DON contents were observed at the 24thhour at 15 ℃, the 40thhour at 25 ℃ and the 48thhour at 35 ℃, respectively. After tempering for 48 h, DON contents in grain were increased by 94.5% at 15 ℃ and 456.1% at 35 ℃, respectively, whereas it was decreased by 35.0% at 25 ℃. From the point of view of reducing DON level, 15 ℃ was not reasonable for the tempering of both wheat cultivars, and tempering at 35 ℃ for 16 h and tempering at 25 ℃ for 24 h appeared to be desirable for Youmai 3 and Yangmai 14, respectively. [Conclusion] The results suggested controlling the tempering temperature and time would be helpful to reduce DON level in grain. | Zhiming GENG Dan YANG Pingping ZHANG Miaoping ZHOU Daoying WANG Fang LIU Muhan ZHANG Yongzhi ZHU | 2014 | Agricultural Science & Technology2014，15，4： | 0 |
| 7 | A Research on the Relationship between Intestinal Flora and Human Longevity显示文摘The exploration of human life and health is advancing with the changes of the times.With the growth of age,the occurrence of chronic diseases of human immunity and organ system is frequent,which has a serious impact on human health.Genes,environment and other random factors determine the outcome of longevity,and intestinal flora is considered to be a decisive factor affecting human health and longevity,mainly because of its huge impact on human immunity,growth and development.The study of the relationship between intestinal flora and longevity is beneficial to improve the health status of the elderly and improve the overall life level of human beings,which has great scientific research value.This review will review the role of intestinal flora in longevity. | Muzi Cui Jianhua Wu Yin Zhang Sixing Liu Shifeng Shuai Liyi Dan PingPing Yan | 2022 | Journal of Advances in Medicine Science2022，5，1： | 0 |
| 8 | SIMPLE ALGORITHM FOR SOIL MOISTURE RETRIEVAL WITH CO-POLARIZED SAR DATA显示文摘In this paper, an empirical methodology to retrieve bare soil moisture by Synthetic Aperture Radar (SAR) is developed. The model is based on Advanced Integral Equation Model (AIEM). Since AIEM cannot express cross-polarized backscattering coefficients accurately, we propose an empirical model to retrieve soil moisture for bare farmland only with co-polarized SAR data. The soil moisture can be obtained by solving an equation of HH and VV polarized data without any field measurements. Both simulated and real SAR data are used to validate the accuracy of the model. This method is especially effective in a large area where the surface roughness is difficult to be completely measured. | Wang Dan Huang Pingping Huang Mo Liu Aijun | 2013 | Journal of Electronics(China)2013，30，3： | 0 |
| 9 | Taxonomy on crane flies in family Tipulidae and Limoniidae(Diptera: Tipuloidea) from Yaoluoping National Nature Reserve, Anhui, China显示文摘The paper reports 13 species from Yaoluoping National Nature Reserve, Anhui, China, including a new species and a new subspecies, Tipula(Emodotipula) alexanderi Men, sp. nov. and Nephrotoma impigra anqingensis Men, subsp. nov. The female of Libnotes(Libnotes) pseudonohirai Men, 2015 is described and illustrated for the first time. The males of Holorusia henana Yang, 1999 and Tipula(Vestiplex) jiangi Yang & Yang, 1991 are redescribed and illustrated with new morphological characters. A key to all species is provided. | Qiulei Men Zhiyong Lu Pingping Sheng Xiang Gui Zhizhong Wang Dan Mu | 2017 | Zoological Systematics2017，42，4： | 0 |
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