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| 1 | Bone tissue engineering via nanostructured calcium phosphate biomaterials and stem cells显示文摘Tissue engineering is promising to meet the increasing need for bone regeneration. Nanostructured calcium phosphate(CaP) biomaterials/scaffolds are of special interest as they share chemical/crystallographic similarities to inorganic components of bone. Three applications of nano-CaP are discussed in this review:nanostructured calcium phosphate cement(CPC); nano-CaP composites; and nano-CaP coatings. The interactions between stem cells and nano-CaP are highlighted, including cell attachment, orientation/morphology, differentiation and in vivo bone regeneration. Several trends can be seen:(i) nano-CaP biomaterials support stem cell attachment/proliferation and induce osteogenic differentiation, in some cases even without osteogenic supplements;(ii) the influence of nano-CaP surface patterns on cell alignment is not prominent due to non-uniform distribution of nano-crystals;(iii) nano-CaP can achieve better bone regeneration than conventional CaP biomaterials;(iv) combining stem cells with nano-CaP accelerates bone regeneration, the effect of which can be further enhanced by growth factors; and(v) cell microencapsulation in nano-CaP scaffolds is promising for bone tissue engineering. These understandings would help researchers to further uncover the underlying mechanisms and interactions in nano-CaP stem cell constructs in vitro and in vivo, tailor nano-CaP composite construct design and stem cell type selection to enhance cell function and bone regeneration, and translate laboratory findings to clinical treatments. | Ping Wang Liang Zhao Jason Liu Michael D Weir Xuedong Zhou Hockin H K Xu | 2014 | Bone Research2014，2，3： | 11 |
| 2 | Nighttime sap flow of Acacia mangium and its implications for nighttime transpiration and stem water storage显示文摘Aims Nighttime sap flow of trees may indicate transpiration and/or recharge of stem water storage at night.This paper deals with the water use of Acacia mangium at night in the hilly lands of subtropical South China.Our primary goal was to reveal and understand the nature of nighttime sap flow and its functional significance.Methods Granier’s thermal dissipation method was used to determine the nighttime sap flux of A.mangium.Gas exchange system was used to estimate nighttime leaf transpiration and stomatal conductance of studied trees.Important Findings Nighttimesap flowwas substantial and showed seasonal variation similar to the patterns of daytime sap flowin A.mangium.Mean nighttime sap flow was higher in the less precipitation year of 2004(1122.4 mm)than in the more precipitation year of 2005(1342.5 mm)since more daytime transpiration and low soil water availability in the relatively dry 2004 can be the cause of more nighttime sap flow.Although vapor pressure deficit and air temperature were significantly correlated with nighttime sap flow,they could only explain a small fraction of the variance in nighttime sap flow.The total accumulated water loss(E_(L))by transpiration of canopy leaves was only;2.6–8.5%of the total nighttime sap flow(E_(t))during the nights of July 17–18 and 18–19,2006.Therefore,it is likely that the nighttime sap flow was mainly used for refillingwater in the trunk.The stem diameter at breast height,basal area and sapwood area explained much more variance of nighttime water recharge than environmental factors and other tree form features,such as tree height,stem length below the branch,and canopy size.The contribution of nighttime water recharge to the total transpiration ranged from 14.7 to 30.3%depending on different DBH class and was considerably higher in the dry season compared to the wet season. | Hua Wang Ping Zhao Dirk Hölscher Quan Wang Ping Lu Xi A.Cai Xiao P.Zeng | 2012 | Journal of Plant Ecology2012，5，3： | 5 |
| 3 | The structural basis of the dominant negative phenotype of the Gαi1β1Y2 G203A/A326S heterotrimer显示文摘 | Ping LIU Ming-zhu JIA X Edward ZHOU Parker W DE WAAL Bradley M DICKSON Bo LlU Li HOU Yan-ting YIN Ya n-yong KANG Yi SHI Karsten MELCHER H Eric XU Yi JIANG | 2016 | Acta Pharmacologica Sinica2016，37，9： | 3 |
| 4 | Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: Risk and prognosis prediction显示文摘 | Manal M. Hassan Ahmed Kaseb Carol J. Etzel Hashem El‐Serag Margaret R. Spitz Ping Chang Katherine S. Hale Mei Liu Asif Rashid Mohamed Shama James L. Abbruzzese Evelyne M. Loyer Harmeet Kaur Hesham M. Hassabo Jean‐Nicolas Vauthey Curtis J. Wray Basmah S. H | 2013 | Mol Carcinog2013，，1： | 2 |
| 5 | Quality control measures for lowering the seroconversion rate of hemodialysis patients with hepatitis B or C virus显示文摘BACKGROUND: Hemodialysis (HD) patients are at high risk of infection by hepatitis B virus (HBV) or hepatitis C virus (HCV). The present study was designed to determine the impact of quality control measures on the prevention of transmission of blood-borne viruses. METHODS: A total of 6182 adult maintenance HD patients from all HD units in Zhejiang Province were recruited on January 1, 2007. The baseline demographic and clinical characteristics were recorded and all patients were followed up until death or survival at 4 years later. The Quality Control Standards of Hemodialysis were gradually implemented in HD units. The HBV or HCV seroconversion rates of the recruited patients were calculated and compared every year during the observation period. RESULTS: The prevalence of HBV was 8.3% at the beginning of the study, and 6.6% for HCV. With the implementation of the HD quality control measures, the HBV seroconversion rate tended to decrease year by year (χ 2 =6.620, P=0.085), and the HCV seroconversion rate decreased significantly (χ 2 =10.41, P=0.015). Compared with the data in 2007, the HBV seroconversion rate (χ 2 =4.204, P=0.040, relative risk ratio 0.393, 95% CI 0.156-0.991) and the HCV seroconversion rate (χ 2 =7.373, P=0.007, relative risk ratio 0.386, 95% CI 0.189-0.787) decreased significantly in 2010. CONCLUSION: Quality control measures for HD decreased the seroconversion rates of HBV or HCV in HD patients, showing that updated quality control measures reduce the risk for transmission of blood-borne viruses in the HD population. | Jing Yuan,Yi Yang, Fei Han, Ping Zhang, Xiao-Ying Du, Hua Jiang and Jiang-Hua Chen The Kidney Disease Center, First Affiliated Hospital, Zhejiang University School of Medicine (Yuan J, Yang Y, Han F, Zhang P, Du XY, Jiang H and Chen JH) and Hemodialysis Quality Control Center of Zhejiang Province (Yuan J, Zhang P, Du XY and Chen JH), Hangzhou 310003, China | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，3： | 2 |
| 6 | Effect of a Patient Education Intervention on Asthma Control and Patient-Doctor Relationship显示文摘 | Yu-Qin Zeng David H Au Shan Cai Evan Carey Fen Jiang Yan Chen Zhi-Jun Liu Ping Chen | 2018 | Chinese Medical Journal2018，，9： | 2 |
| 7 | Measurements of refractive index sensitivity using long period graing refract meter显示文摘 | Chong J H Shum Ping Haryono H | 2004 | Optics Communications2004，229，126： | 1 |
| 8 | Antibacterial zeolite with a high silver-loading content and excellent antibacterial performance显示文摘 | YUZHEN Z YUEQUAN D PING H FAQIN D | 2014 | RSC Advance2014，，4： | 1 |
| 9 | Induction of allogeneic mixed chimerism by immature dendritic cells and bone marrow transplantation leads to prolonged tolerance to major histocompatibility complex disparate allografts显示文摘 | PING Y SI D X QIU Z H | 2009 | Immunology2009，127，4： | 1 |
| 10 | Poly(vinyl alcohol)/poly (vinylpyrrolidone)interp-enetrating polymer network:Synthesis and pervaporation properties显示文摘 | Lu J Zhou J Q Ping Z H | 2003 | J Appl Polym Sci2003，89，10： | 1 |
| 11 | Preparation of N-alkyl-O-sulfate chitosan derivatives and micellar solubilization of taxol显示文摘 | Zhang C Ping Q Zhang H J | 2003 | Carbohydrate Polymers2003，54，： | 1 |
| 12 | The influence of the ion-atom potential on molecular dynamics simulations of sputtering 显示文摘 | Shapiro M H Ping Lu | 2004 | Nuclear Instruments and Methods in Physics Research B2004，215，： | 1 |
| 13 | The effect of yttrium addition on the isothermal oxidation behavior of sputtered K38 nanocrystalline coating at 1273 K in air显示文摘 | W Wen Y Ping F H Wang | 2007 | Surface & Coatings Technology2007，201，1617： | 1 |
| 14 | In situ Fourier transform infrared attenuated total reflection (FTIR-ATR) spectroscopic investigations on the base-acid transitions of leucoemeraldine显示文摘 | Ping Z Nauer G E Neugebauer H | 1997 | Electrochimica Acta1997，42，11： | 1 |
| 15 | TEM investigations on martensite in a Ti-Nb-based shape memory alloy显示文摘 | Cui C Y Yin F X et at | 2006 | Scripta Materialia2006，54，： | 1 |
| 16 | Southwest Indian Ocean SST variability:Its local effect and remote influence on Asian monsoons显示文摘 | Annamalaih H Liu Ping Xie Shang-ping | 2005 | J Climate2005，18，20： | 1 |
| 17 | Downregulation of Notch1 and its potential correlation with epidermal growth factor receptor signalling in tongue squamous cell carcinoma显示文摘 | Huang H J Ping F Y Hu J A | 2010 | Br J Oral Maxillofac Surg2010，48，1： | 1 |
| 18 | Support vector machines with simulated annealing algorithms in electricity load forecasting显示文摘 | Ping F P Wei C H | 2005 | Energy Conversion and Management2005，，46： | 1 |
| 19 | Association of myostatin gene poly- morphisms with obesity in Chinese north Han human subjects 显示文摘 | Pan H Ping XC Zhu HI | 2012 | Gene2012，494，2： | 1 |
| 20 | Application of the Hem-o-lok ligation system in laparoscopic nephrectomy 显示文摘 | Ping H Xing NZ Zhang JH | 2010 | Surg Endosc2010，24，6： | 1 |
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