|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Vascular endothelial growth factor receptor 2(VEGFR-2) plays a key role in vasculogenic mimicry formation,neovascularization and tumor initiation by Glioma stem-like cells显示文摘Human glioblastomas(GBM)are thought to be initiated by glioma stem-like cells(GSLCs).GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells.Here,we report a critical role of GSLCs in the formation of vasculogenic mimicry(VM),which defines channels lined by tumor cells to supply nutrients to early growing tumors and | Yao X Ping Y Liu Y Chen K Yoshimura T Liu M Gong W Chen C Niu Q Guo D Zhang X Wang JM Bian X | 2013 | 中国神经肿瘤杂志2013，11，3： | 23 |
| 2 | 创新显示文摘XDebloat框架有效对抗安卓应用臃肿化创新点人类有白色、棕色和米色3种不同功能的脂肪。白色脂肪负责储存热量;棕色脂肪负责燃烧脂肪产生热量;最新发现的米色脂肪在静息时表现出白色脂肪功能,在被激活后则具有脂肪棕色的潜力,可促进热量产生和脂肪消耗。因此,如何安全有效地激活米色脂肪成为治疗肥胖和代谢疾病的重要研究方向。华东师范大学生命科学学院马欣然研究员、徐凌燕研究员联合其他研究团队,共同发现了米色脂肪局部热疗的新方法,可以改善代谢紊乱并治疗肥胖。 | LI Y WANG D PING X 陈西 | 2022 | 张江科技评论2022，，2： | 14 |
| 3 | Characterization of soil organic matter fractions of tundra soils in Arctic Alaska by carbon 13 nuclear magnetic resonance spectroscopy 显示文摘 | Dai X Y Ping C L Candler R | 2001 | Soil Science Society of America Journal2001，65，： | 2 |
| 4 | Quality control measures for lowering the seroconversion rate of hemodialysis patients with hepatitis B or C virus显示文摘BACKGROUND: Hemodialysis (HD) patients are at high risk of infection by hepatitis B virus (HBV) or hepatitis C virus (HCV). The present study was designed to determine the impact of quality control measures on the prevention of transmission of blood-borne viruses. METHODS: A total of 6182 adult maintenance HD patients from all HD units in Zhejiang Province were recruited on January 1, 2007. The baseline demographic and clinical characteristics were recorded and all patients were followed up until death or survival at 4 years later. The Quality Control Standards of Hemodialysis were gradually implemented in HD units. The HBV or HCV seroconversion rates of the recruited patients were calculated and compared every year during the observation period. RESULTS: The prevalence of HBV was 8.3% at the beginning of the study, and 6.6% for HCV. With the implementation of the HD quality control measures, the HBV seroconversion rate tended to decrease year by year (χ 2 =6.620, P=0.085), and the HCV seroconversion rate decreased significantly (χ 2 =10.41, P=0.015). Compared with the data in 2007, the HBV seroconversion rate (χ 2 =4.204, P=0.040, relative risk ratio 0.393, 95% CI 0.156-0.991) and the HCV seroconversion rate (χ 2 =7.373, P=0.007, relative risk ratio 0.386, 95% CI 0.189-0.787) decreased significantly in 2010. CONCLUSION: Quality control measures for HD decreased the seroconversion rates of HBV or HCV in HD patients, showing that updated quality control measures reduce the risk for transmission of blood-borne viruses in the HD population. | Jing Yuan,Yi Yang, Fei Han, Ping Zhang, Xiao-Ying Du, Hua Jiang and Jiang-Hua Chen The Kidney Disease Center, First Affiliated Hospital, Zhejiang University School of Medicine (Yuan J, Yang Y, Han F, Zhang P, Du XY, Jiang H and Chen JH) and Hemodialysis Quality Control Center of Zhejiang Province (Yuan J, Zhang P, Du XY and Chen JH), Hangzhou 310003, China | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，3： | 2 |
| 5 | Modification and identification of a vector for making a large phage antibody library显示文摘背景大噬菌体抗体图书馆被用来获得高亲密关系的人的抗体,并且 Loxp/cre 地点特定的再结合系统是为构造一个大噬菌体抗体图书馆的一个潜在的方法。在现在的学习,没有对相应再结合和向量并且这样的表达式函数的损害,噬菌体抗体图书馆向量 pDF 被重建更快速并且方便地构造 diabody 与 diabodies.Methods scFv 的准备集成大噬菌体抗体图书馆的建设被重叠聚合酶链反应( PCR )获得扩大与最新设计的 VL 和 VH 扩展教材。loxp511 是由 VL 和 VH 的 flanked,编码序列的 endonuclease ACC 在 loxp511 的双方上被介绍。scFv 被克隆进向量 pDF 获得向量 pDscFv。向量表示功能被识别, diabody 准备的可行性被评估。一个大噬菌体抗体图书馆在 pDscFv 被构造。几抗原被用来屏蔽抗体图书馆,抗体图书馆的质量是 evaluated.Results 噬菌体抗体图书馆表示向量 pDscFv 成功地被构造并且证实了表示功能的 scFv。用这向量构造的大噬菌体抗体图书馆差异高。在 6 抗原上图书馆屏蔽证实了特定的抗体的产生到这些抗原。二抗体受到酶的消化并且与重建的向量 pDscFv 保留的功能的 expression.Conclusions 被准备进 diabody 它的再结合能力和表达式函数和罐头被用来构造大噬菌体抗体图书馆。它能作为一个方便、快的方法被使用在简单酶的消化以后准备 diabodies,它便于抗体治疗的临床的试用和应用。 | ZHANG Guo-min CHEN Yü-ping GUAN Yuan-zhi WANG Yan AN Yun-qing | 2007 | Chinese Medical Journal2007，，22： | 2 |
| 6 | Ischemia preconditioning induces selective translocation of protein kinase C isoforms epsilon and eta in the heart of concious rabbits without subcellar redistribution of total protein kinase C activity显示文摘 | Zhang J Qiu Y | 1997 | Circ Res1997，81，3： | 1 |
| 7 | IrrE, a global regulator of extreme radiation resistance inDeinococcus radiodurans, enhances salt tolerance in Escherichia coli and Brassica napus显示文摘 | Pan J Wang J Zhou Z Yan Y Zhang W Lu W Ping S Dai Q Yuan M Feng B Hou X Zhang Y Ma R Liu T Feng L Wang L Chen M Lin M | 2009 | PloS One2009，4，2： | 1 |
| 8 | Discovery of novel steroidal pyranoxindole hybrids as cytotoxic agents显示文摘 | Bin Y Ping P Q Xiao J S | 2014 | Steroids2014，88，： | 1 |
| 9 | Three phenylethanoid glycosides and an iridoid glycoside from roots of Picrorhiza scrophulariiflora 显示文摘 | LI Jian-xin LI Ping TEZUKA Y | 1998 | Phytochemistry1998，48，： | 1 |
| 10 | Effect of SNP at position 40237 in exon 7 of the TPH2 gene on susceptibility to suicide显示文摘 | Ke L Qi ZY Ping Y el al | 2006 | Brain Res2006，1122，1： | 1 |
| 11 | Induction of allogeneic mixed chimerism by immature dendritic cells and bone marrow transplantation leads to prolonged tolerance to major histocompatibility complex disparate allografts显示文摘 | PING Y SI D X QIU Z H | 2009 | Immunology2009，127，4： | 1 |
| 12 | Effects of formulation factors on encapsulation efficiency and release behaviour in vitro of huperzine APLGA microspheres 显示文摘 | FU X PING Q GAO Y | 2002 | J Microencapsul2002，55，1： | 1 |
| 13 | Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy显示文摘 | Takeishi Y Ping P Bolli R | 2000 | Circ Res2000，86，： | 1 |
| 14 | The effect of yttrium addition on the isothermal oxidation behavior of sputtered K38 nanocrystalline coating at 1273 K in air显示文摘 | W Wen Y Ping F H Wang | 2007 | Surface & Coatings Technology2007，201，1617： | 1 |
| 15 | Genetic factors of susceptibility and of severity in primary biliary cirrhosis显示文摘 | Poupon R Ping C Chretien Y | 2008 | J Heoatolo2008，39，： | 1 |
| 16 | Enhanced investigation of CO methanation over Ni/A1203 catalysts for synthetic natural gas productian显示文摘 | Hu D C Gao J J Ping Y | 2012 | Ind Eng Chem Res2012，51，13： | 1 |
| 17 | TEM investigations on martensite in a Ti-Nb-based shape memory alloy显示文摘 | Cui C Y Yin F X et at | 2006 | Scripta Materialia2006，54，： | 1 |
| 18 | Downregulation of Notch1 and its potential correlation with epidermal growth factor receptor signalling in tongue squamous cell carcinoma显示文摘 | Huang H J Ping F Y Hu J A | 2010 | Br J Oral Maxillofac Surg2010，48，1： | 1 |
| 19 | Cardiac toxic effects of trans-2-hexenal are mediated by induction of cardiomyocyte apoptotic pathways显示文摘 | Ping P Baines CP Gu Y | 2003 | Cardiovasc Toxicol2003，3，4： | 1 |
| 20 | Lecithin Vesicular for Transdermal Delivery of Cyclosporin A显示文摘 | Guo J X Ping Q N Chen Y | 2000 | Int J pharm2000，，194： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员