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| 1 | Serological diagnosis of Epstein-Barr virus infection: Problems and solutions显示文摘Serological tests for antibodies specific for Epstein-Barr virus(EBV) antigens are frequently used to define infection status and for the differential diagnosis of other pathogens responsible for mononucleosis syndrome. Using only three parameters [viral capsid antigen(VCA) Ig G, VCA Ig M and EBV nuclear antigen(EBNA)-1 Ig G],it is normally possible to distinguish acute from past infection: the presence of VCA Ig M and VCA Ig G without EBNA-1 Ig G indicates acute infection, whereas the presence of VCA Ig G and EBNA-1 Ig G without VCA Ig M is typical of past infection. However, serological findings may sometimes be difficult to interpret as VCA Ig G can be present without VCA Ig M or EBNA-1 Ig G in cases of acute or past infection, or all the three parameters may be detected simultaneously in the case of recent infection or during the course of reactivation. A profile of isolated EBNA-1 Ig G may also create some doubts. In order to interpret these patterns correctly, it is necessary to determine Ig G avidity, identify anti-EBV Ig G and Ig M antibodies by immunoblotting, and look for heterophile antibodies, anti-EA(D) antibodies or viral genome using molecular biology methods. These tests make it possible to define the status of the infection and solve any problems that may arise in routine laboratory practice. | Massimo De Paschale Pierangelo Clerici | 2012 | World Journal of Virology2012，1，1： | 30 |
| 2 | Microbiology laboratory and the management of motherchild varicella-zoster virus infection显示文摘Varicella-zoster virus, which is responsible for varicella(chickenpox) and herpes zoster(shingles), is ubiquitous and causes an acute infection among children, especially those aged less than six years. As 90% of adults have had varicella in childhood, it is unusual to encounter an infected pregnant woman but, if the disease does appear, it can lead to complications for both the mother and fetus or newborn. The major maternal complications include pneumonia, which can lead to death if not treated. If the virus passes to the fetus, congenital varicella syndrome, neonatal varicella(particularly serious if maternal rash appears in the days immediately before or after childbirth) or herpes zoster in the early years of life may occur depending on the time of infection. A Microbiology laboratory can help in the diagnosis and management of mother-child infection at four main times:(1) when a pregnant woman has been exposed to varicella or herpes zoster, a prompt search for specific antibodies can determine whether she is susceptible to, or protected against infection;(2) when a pregnant woman develops clinical symptoms consistent with varicella, the diagnosis is usually clinical, but a laboratory can be crucial if the symptoms are doubtful or otherwise unclear(atypical patterns in immunocompromised subjects, patients with post-vaccination varicella, or subjects who have received immunoglobulins), or if there is a need for a differential diagnosis between varicella and other types of dermatoses with vesicle formation;(3) when a prenatal diagnosis of uterine infection is required in order to detect cases of congenital varicella syndrome after the onset of varicella in the mother; and(4) when the baby is born and it is necessary to confirm a diagnosis of varicella(and its complications), make a differential diagnosis between varicella and other diseases with similar symptoms, or confirm a causal relationship between maternal varicella and malformations in a newborn. | Massimo De Paschale Pierangelo Clerici | 2016 | World Journal of Virology2016，5，3： | 7 |
| 3 | Haemolysis: an overview of the leading cause of unsuitable specimens in clinical laboratories显示文摘 | Giuseppe Lippi Norbert Blanckaert Pierangelo Bonini Sol Green Steve Kitchen Vladimir Palicka Anne J. Vassault Mario Plebani | 2008 | Clinical Chemistry and Laboratory Medicine2008，，6： | 2 |
| 4 | Increased survival of cirrhotic patients with a hepatocellular carcinoma detected during surveillance显示文摘 | Angelo Sangiovanni Ersilio Del Ninno Pierangelo Fasani Cristina De Fazio Guido Ronchi Raffaella Romeo Alberto Morabito Roberto de Franchis Massimo Colombo | 2004 | Gastroenterology2004，，4： | 2 |
| 5 | Human endostatin-derived synthetic peptides possess potent antiangiogenic properties in vitro and in vivo 显示文摘 | Maria GC Sandra P Pierangelo F | 2003 | Experimental Cell Research2003，283，2： | 1 |
| 6 | Carbon nanotubes for cold electron soreces 显示文摘 | Pierangelo Groning Pascal Ruffieux Louis Schlapbach | 2003 | Advanced Engineering Materials2003，5，8： | 1 |
| 7 | Halomonas alkaliantarctica sp. nov., isolated from saline lake Cape Russell in Antarctica, an alkalophilic moderately halophilic, exopolysaccharide-producing bacterium显示文摘 | Annarita Poli Enrico Esposito Pierangelo Orlando Licia Lama Assunta Giordano Francesca de Appolonia Barbara Nicolaus Agata Gambacorta | 2006 | Systematic and Applied Microbiology2006，，1： | 1 |
| 8 | A Quasi-Neutral Limit in a Hydrodynamic Model for Charged Fluids显示文摘 | Ingenuin Gasser Pierangelo Marcati | 2003 | Monatshefte für Mathematik2003，，3： | 1 |
| 9 | Endocannabinoid signalling in the blood of patients with schizophrenia显示文摘 | Nicola DM Luciano DP Pierangelo O | 2003 | Lipids in Health and Disease2003，2，： | 1 |
| 10 | Delayed-onset periph-eral blood cytopenia after rituximab:Frequency and risk factor as-sessment in a consecutive series of 77 treatments显示文摘 | Chiara C Pierangelo S Salvatore C | 2006 | Leukemiaand Lymphoma2006，47，6： | 1 |
| 11 | Diamond nucleation from the gas phase onto cold-worked Co-cemented tungsten carbide 显示文摘 | Riceardo Polini Pierangelo D'Antonio Enrico Traversa | 2003 | Diamond and Related Materials2003，12，： | 1 |
| 12 | Measurement and prediction of evaporator shell-side pressure drop 显示文摘 | Davide Del Col Angelo Muzzolon Pierangelo Piubello | 2005 | International Journal of Refrigeration2005，28，： | 1 |
| 13 | Haemolysis: an overview of the leading cause of unsuitable specimens in clinical laboratories显示文摘 | Giuseppe Lippi Norbert Blanckaert Pierangelo Bonini Sol Green Steve Kitchen Vladimir Palicka Anne J. Vassault Mario Plebani | 2008 | Clinical Chemistry and Laboratory Medicine2008，，6： | 1 |
| 14 | Semantic Indexing of Soccer Audio-Visual Sequence:A multimodal approach based on controlled Markov chains显示文摘 | Ricardo Lenardi Pierangelo Migliorati Maria Prandini | 2004 | IEEE Trans on Circuits & System for Video Technology2004，5，： | 1 |
| 15 | Monocyte chemoattractant protein-1 (MCP-1) gene polymorphism and risk of Alzheimer’s disease in Italians显示文摘 | Roberto Pola Andrea Flex Eleonora Gaetani Anna S Proia Pierangelo Papaleo Angela Di Giorgio Giuseppe Straface Giovanni Pecorini Michele Serricchio Paolo Pola | 2004 | Experimental Gerontology2004，，8： | 1 |
| 16 | The ketogenic diet:From molecular mechanisms to clinical effects显示文摘 | John Freeman Pierangelo Veggiotti Giovanni Lanzi | 2006 | Epilepsy Research2006，68，： | 1 |
| 17 | Feasibility and Reproducibility of Three-Dimensional Echocardiographic Assessment of Right Ventricular Size and Function in Pediatric Patients显示文摘 | Pierangelo Renella Gerald R. Marx Jing Zhou Kimberlee Gauvreau Tal Geva | 2014 | Journal of the American Society of Echocardiography2014，，： | 1 |
| 18 | Responses to divergent selection for cob color in maize显示文摘 | Pierangelo Landi Maria A. Canè Elisabetta Frascaroli | 2008 | Euphytica2008，，3： | 1 |
| 19 | Dia mond nucleation from the gas phase onto cold-worked Co--ce mented tungsten carbide 显示文摘 | Riccardo Polini Pierangelo D'Antonio Enrico Traversa | 2003 | Diamond and Related Materials2003，12，： | 1 |
| 20 | The role of bacteria in the formation of cold seep carbonates: geological evidence from Monferrato ( Tertiary, NW Italy) 显示文摘 | Simona Cavagna Pierangelo Clari Luca Martire | 1999 | Sedimentary Geology1999，126，： | 1 |
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