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| 1 | Expression of matrix metalloproteinases 2 and 9 in human gastric cancer and superficial gastritis显示文摘AIM:To assess expression of matrix metalloproteinases 2(MMP2)and MMP9 in gastric cancer,superficial gastritis and normal mucosa,and to measure metalloproteinase activity.METHODS:MMP2 and MMP9 mRNA expression was determined by quantitative real-time polymerase chain reaction.Normalization was carried out using three different factors.Proteins were analyzed by quantitative gelatin zymography(qGZ).RESULTS:18S ribosomal RNA(18SRNA)was very highly expressed,while hypoxanthine ribosyltransferase-1(HPRT-1)was moderately expressed.MMP2 was highly expressed,while MMP9 was not detected or lowly expressed in normal tissues,moderately or highly expressed in gastritis and highly expressed in cancer.Relative expression of 18SRNA and HPRT-1 showed no significant differences.Significant differences in MMP2 and MMP9 were found between cancer and normal tissue,but not between gastritis and normal tissue.Absolute quantification of MMP9 echoed this pattern,but differential expression of MMP2 proved conflictive.Analysis by qGZ indicated significant differences between cancer and normal tissue in MMP-2,total MMP-9,250 and 110 kDa bands.CONCLUSION:MMP9 expression is enhanced in gastric cancer compared to normal mucosa;interpretation of differential expression of MMP2 is difficult to establish. | Clara Luz Sampieri Sol de la Pea Mariana Ochoa-Lara Roberto Zenteno-Cuevas Kenneth León-Córdoba | 2010 | World Journal of Gastroenterology2010，16，12： | 46 |
| 2 | Radiometric cross-calibration of the CBERS-02 CCD camera with the TERRA MODIS显示文摘For the application of the CCD camera, the most important payload on CBERS-02, the key is to provide long-term stable radiometric calibration coefficients. Although the vicarious calibration had been proved successful, it had its limitations such as test site requirement and unsuitable for historical data. Cross-calibration is one of the alternative methods, but it needs synchro surface spectrum to achieve spectral band matching factors. Our effort is to probe the influences on these factors. Simulations with a lot of surface spectrum showed that the factors changed with the viewing geometry, atmospheric condition and surface targets. However, simulating with the same viewing geometry and atmospheric condition, the spectral band matching factors of the same or similar surface targets’ spectrum acquired from different dates and different places would like to be consistent to each other within 1%―5%. Thus, the synchro measurement data can be substituted by the same or similar target from other source. Based on this method, using the MODIS as the reference, the cross-calibration was performed for CCD camera. The research demonstrated that the traditional method with single calibration site was inappropriate for CCD camera, since the offsets for its four spectral bands were not zeros. With four calibration sites, these offsets were obtained. And the camera was detected to degrade with dates based on four times of cross-calibrations. | LI Xiaoying1,2,3, GU Xingfa1,3,4, MIN Xiangjun5, YU Tao1,3, FU Qiaoyan5, ZHANG Yong1,2,3 & LI Xiaowen1,3 1. State Key Laboratory of Remote Sensing Science, Jointly Sponsored by the Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University, Beijing 100101, China 2. Graduate University of Chinese Academy of Sciences, Beijing 100039, China 3. The Center for National Spaceborne Demonstration, Beijing 100101, China 4. Institut National de la Recherche Agronomique, Climat Sol Environnement, 84914 Avignon, France 5. China Center for Resource Satellite Data and Application, Beijing 100830, China | 2005 | Science China(Technological Sciences)2005，48，S2： | 15 |
| 3 | Periodontitis-induced systemic inflammation exacerbates atherosclerosis partly via endothelial–mesenchymal transition in mice显示文摘Growing evidence suggests close associations between periodontitis and atherosclerosis.To further understand the pathological relationships of these associations,we developed periodontitis with ligature placement around maxillary molars or ligature placement in conjunction with Porphyromonas gingivalis lipopolysaccharide injection at the ligature sites (ligature/P.g.LPS) in Apolipoprotein E knock out mice and studied the atherogenesis process in these animals.The mice were fed with high fat diet for 11 weeks and sacrificed for analyzing periodontitis,systemic inflammation,and atherosclerosis.Controls did not develop periodontitis or systemic inflammation and had minimal lipid deposition in the aortas,but mice receiving ligature or ligature/P.g.LPS showed severe periodontitis,systemic inflammation,and aortic plaque formation.The aortic plaque contained abundant macrophages and cells expressing both endothelial and mesenchymal cell markers.The severity of periodontitis was slightly higher in mice receiving ligature/P.g.LPS than ligature alone,and the magnitude of systemic inflammation and aortic plaque formation were also notably greater in the mice with ligature/P.g.LPS.These observations indicate that the development of atherosclerosis is due to systemic inflammation caused by severe periodontitis.In vitro,P.g.LPS enhanced the secretion of pro-inflammatory cytokines from macrophages and increased the adhesion of monocytes to endothelial cells by upregulating the expression of adhesion molecules from endothelial cells.Moreover,secretory proteins,such as TNF-α,from macrophages induced endothelial–mesenchymal transitions of the endothelial cells.Taken together,systemic inflammation induced by severe periodontitis might exacerbate atherosclerosis via,in part,causing aberrant functions of vascular endothelial cells and the activation of macrophages in mice. | Jin Sook Suh Sol Kim Kristina I.Bostrom Cun-Yu Wang Reuben H.Kim No-Hee Park | 2019 | International Journal of Oral Science2019，11，3： | 15 |
| 4 | A Talk on the Translation of Volume V of Chairman Mao’s Selected Works显示文摘I should first mention the collective style of work in preparing the translation of VolumeV which was admirable.We all had only one objective which was to make the translationas good as possible,and everything was subordinated to that.The second point I would like to make is that every effort was made to correct andimprove at each stage right to the very end,right up to and including the page proofs.This is essential.Of course it is virtually impossible to eliminate all errors;the fairly obviousones should have been disposed of before the two final corrections,and the process ismuch more difficult where it is not a question of eliminating errors but of choosing bet- | Sol Adler | 1980 | 中国翻译1980，，1： | 13 |
| 5 | Severe acute pancreatitis due to tamoxifen-induced hypertriglyceridemia with diabetes mellitus显示文摘The side effects of tamoxifen are generally mild, including the effect on lipoprotein metabolism. However, there are few cases of severe tamoxifen induced hypertriglyceridemia. Hypertriglyceridemia is a marked risk factor for acute pancreatitis and approximately 2% to 5% of cases of acute pancreatitis are related to drugs. We report on tamoxifen-induced hypertriglyceridemia and acute pancreatitis in a 40 years old woman with type 2 diabetes mellitus occurred by dexamethasone. She was treated with insulin infusion and fenofibrate, and goserelin acetate was started instead of tamoxifen after discharge from the hospital. Also, probable pathogenic hypotheses about the correlation between tamoxifen and dexamethasone induced type 2 diabetes mellitus on severe acute pancreatitis are provided. Clinicians should take care of risks of severe acute pancreatitis on using tamoxifen, especially for patients with dexamethasone induced diabetes mellitus. These individuals should undergo pre-post tamoxifen lipid screening and careful history taking of drugs, including dexamethasone. | Young Ae Kim Sol Lee Ji Woong Jung Yu Jin Kwon Gyeong Bok Lee Dong Gue Shin Sang Su Park Jin Yun Yong-Seog Jang Dong Hui Cho | 2014 | Chinese Journal of Cancer Research2014，26，3： | 12 |
| 6 | 慢加急性肝衰竭进展显示文摘2017年3月Gut发表了Hernaez等的综述《慢加急性肝衰竭进展》[Hernaez R,solaE,MoreauR,eta1.Acute—on—chronicliver failure:anupdate.Gut.2017.66:541—553]。慢加急性肝功能衰竭(acute—on—chronicliver failure,ACLF)是一种发生在有基础慢性肝病或者代偿期肝硬化患者中的,以由不同类型的损害导致的急性的严重肝功能异常为特征的综合征,短期病死率高,预后与急性肝衰竭相似。目前有很多不同的定义标准,2009年亚太肝病研究协会(APASL)提出了ACLF的第1版共识,2014年进行了更新。 | 姚勤伟 欧阳颖 孟庆华 Hernaez R Solà E Moreau R | 2017 | 北京医学2017，39，9： | 6 |
| 7 | Absolute radiometric calibration of CBERS-02 IRMSS thermal band显示文摘Based on the laboratory calibration before launch of CBERS-02 IRMSS thermal infrared channel, the onboard blackbody calibration, the radiometric cross- calibration against TERRA MODIS corresponding channel and the in-flight field calibration at Lake Qinghai: water surface radiometric calibration test site of China on Aug. 17, 2004 are carried out in this research. When making onboard blackbody calibration of CBERS-02 IRMSS, it is necessary to understand inside structures and light path in IRMSS camera and receive and process calibration blackbody signals at normal and high temperatures. Onboard blackbody calibration results of each detector are very important to relative radiometric calibration of images processing and absolute radiometric calibration of each detector. In-flight field calibration mainly contains field experiments, obtaining synchronous images, spectrum marching and MODTRAN radiative transmi- ssion computation. Radiometric cross-calibration of CBERS-02 IRMSS thermal band against TERRA MODIS selected 6 times synchronous images of two sensors passing through Lake Qinghai and Lake Taihu from August to December, 2004 to compute the cross calibration data. Combining the in-flight field calibration and radiometric cross calibration data, the absolute radiometric calibration coefficients are calculated by the linear regression method. This new calibration model can obviously control the radiometric calibration uncertainties aroused by the single point method used in the in-flight calibration of CBERS-02 IRMSS, this kind of sensors cannot receive the cosmic background radiation. In this research, the radiometric calibration coefficients obtained through the linear regression model are 8.53 (gain, unit: DN/W m?2sr?1μm?1) and 44.92 (offset, unit: DN). | ZHANG Yong1,2,3, GU Xingfa1,3,4, YU Tao1,3, ZHANG Yuxiang5, CHEN Liangfu1,3, LI Xiaoying1,2,3, LI Xiaowen1,3 & HE Liming6 1. State Key Laboratory of Remote Sensing Science, Jointly Sponsored by the Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University, Beijing 100101, China 2. Graduate University of Chinese Academy of Sciences, Beijing 100039, China 3. The Center for National Spaceborne Demonstration, Beijing 100101, China 4. Institut National de la Recherche Agronomique, Climat Sol Environnement, 84914 Avignon, France 5. National Satellite Meteorological Center, Beijing 100081, China 6. State Environmental Protection Administration, Beijing 100029, China | 2005 | Science China(Technological Sciences)2005，48，S2： | 6 |
| 8 | 中国西藏甲螨新种和新纪录种记述(蜱螨亚纲 :甲螨亚目 )(英文)显示文摘报道西藏甲螨 4新种和 6新纪录种。标本采于西藏东南色季拉山 ,海拔 3640~ 4 80 0m。新种为 :粒小隅甲螨MicrotegeusgranulatusWangetShen ,sp .nov .,西藏真翅背甲螨EupterotegaeusxizangensisWangetSolhoy ,sp .nov .,头新裸甲螨NeogymnobatescapitatusWangetSolhoy ,sp .nov .,山溯甲螨Birsteiniusmonti colusWangetShen ,sp .nov .。新纪录种为 :纽氏平懒甲螨PlatynothrusnumataiAoki,塞氏矮汉甲螨Nan hermanniasellnickiForsslund ,杜氏小赫甲螨HermannielladubininiSitnikova ,多齿刀肋甲螨CultroribuladentataWillmann ,曲波甲螨Unduloribatesundulatus(Berlese) ,毛暗色甲螨Fuscozetessetosus(C .L .Koch)。本文报道的波甲螨属、溯甲螨属、新裸甲螨属和暗色甲螨属为中国首次发现。 | 王慧芙 Torstein SOL HOY 沈静 徐汝梅 | 2001 | 动物分类学报2001，26，4： | 5 |
| 9 | Efficacy of Pegylated Interferon Monotherapy versus Sequential Therapy of Entecavir and Pegylated Interferon in Hepatitis B e Antigen-Positive Hepatitis B Patients: A Randomized, Multicenter, Phase IIIb Open-Label Study (POTENT Study)显示文摘 | Dae Won Jun Sang Bong Ahn Tae Yeob Kim Joo Hyun Sohn Sang Gyune Kim Se Whan Lee Byung Ho Kim Dong Joon Kim Ja Kyung Kim Hyoung Su Kim Seong Gyu Hwang Won Choong Choi Won Young Tak Heon Ju Lee Ki Tae Yoon Byung Cheol Yun Sung Wook Lee Soon Koo Baik Seung Ha Park Ji Won Park Sol Ji Park Ji Sung Lee | 2018 | Chinese Medical Journal2018，，14： | 5 |
| 10 | In flight MTF monitoring and compensation for CCD camera on CBERS-02显示文摘In this article, the approach of simulating ideal tarp scene was proposed to determine the MTF for CCD camera on CBERS-02. The MTF acquired from this technique was compared to those from some common methods. MTFs achieved from different approaches were employed to compensate the CCD images based on three restoration algorithms: the iterative method, the Wiener filter and the modified inverse filter (MIF). The two-dimensional MTF was established with the value at frequency 0.5 for 45° directional MTF as the value at its four corners. This article addressed the variations of the restored CCD images with different techniques of constructing two-dimensional MTF, restoring algorithms and determining the in-flight MTFs. Results showed images restored with the MTF determined from the technique of simulating ideal tarp scene represent the real scene best. And the restoration technique based on the MIF would produce better restored images than the other two techniques. This research also demonstrated that the two-dimensional MTF used for restoration should be interpolated under the control of the MTF for 45° axis, rather than by multiplying the cross-orbit MTF with along-orbit MTF. | GU Xingfa1,2,3, LI Xiaoying1,2,4, MIN Xiangjun5, YU Tao1,2, SUN Jijuan5, ZENG Yong1,2,4, XU Hua1,2 & GUO Ding2,6 1. State Key Laboratory of Remote Sensing Science, Jointly Sponsored by the Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University, Beijing 100101, China 2. The Center for National Spaceborne Demonstration, Beijing 100101, China 3. Institut National de la Recherche Agronomique, Climat Sol Environnement, 84914 Avignon, France 4. Graduate University of Chinese Academy of Sciences, Beijing 100039, China 5. China Center for Resource Satellite Data and Application, Beijing 100830, China 6. University of Electronic Science and Technology of China, Chengdu 610054, China | 2005 | Science China(Technological Sciences)2005，48，S2： | 4 |
| 11 | 基于定量宏基因组学评估肝硬化患者肠道菌群的变化与慢加急性肝衰竭及预后的关系显示文摘【据Gastroenterology 2020年9月报道】题:基于定量宏基因组学评估肝硬化患者肠道菌群的变化与慢加急性肝衰竭及预后的关系(作者SoléC等)肝硬化与肠道菌群组成的改变有关。慢加急性肝衰竭(ACLF)是肝硬化最严重的临床阶段,但目前仍缺乏使用定量宏基因组学研究ACLF中肠道菌群改变的信息。 | SOLéC GUILLY S Da SILVA K 邵玥明 温晓玉 | 2020 | 临床肝胆病杂志2020，36，11： | 4 |
| 12 | 文献快报(4):童年期不良经历与成年期生理损害的关系--1958年英国出生队列研究显示文摘适应负荷(allostatic load,AL)是一种衡量躯体受到长期压力时所导致生理损害程度的评价工具,这种损害可能部分是由于生命早期不良经历所致,因此这个指标通常可作为评价慢性应激暴露水平的生物标志物。Barboza Solís C等通过对童年期不良经历(adverse childhood experiences,ACEs)与中年期适应负荷关系的研究来进一步验证远期不良经历可导致生理功能损害的研究假设。该课题组利用1958年英国出生队列,其中女性3 782人,男性3 753人,共随访了7次。在儿童7岁、11岁和16岁时分别调查了童年期不良经历;在队列人群44岁时,采用神经内分泌系统、免疫与炎症系统、代谢系统、呼吸与心血管系统4个系统14个指标作为评价其适应负荷的可操作性指标,同时调查了健康行为、 | BARBOZA SOLíS C KELLY-IRVING M FANTIN R 苏普玉 | 2015 | 中国学校卫生2015，36，3： | 3 |
| 13 | TRICHOGENTM VEG防脱精华液研究显示文摘使用质量分数10%的TRICHOGEN^(TM) VEG防脱精华液,对40名有严重脱发症状的男性每2天做1次头皮护理,持续16周。结果表明TRICHOGEN^(TM) VEG防脱精华液能够刺激细胞代谢,促进表皮微循环。从生长初期/生长末期(A/T)比值来看,使用该产品后,A/T值增加了113%,表明TRICHOGEN^(TM) VEG具有较强的头发再生作用。 | AURéLIE Courtois SOLèNE Mine VALéRIE André-frei DAVID Bothorel | 2017 | 日用化学品科学2017，40，6： | 3 |
| 14 | 椰子油:一种控制猪致病菌的新选择显示文摘在断奶期,许多细菌都能影响仔猪的肠道健康。日粮中添加中链脂肪酸,则有助于提高仔猪的生产性能和健康。从哪里提取这些中链脂肪酸呢?可从椰子油中提取。 | 周美丽 邵建忠 韩浩月 Monica Puyalto Cinta Sol Juan Jose Mallor Norel | 2017 | 国外畜牧学(猪与禽)2017，37，11： | 3 |
| 15 | A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity显示文摘Understanding the immune responses elicited by SARS-CoV-2 infection is critical in terms of protection against reinfection and,thus,for public health policy and vaccine development for COVID-19.In this study,using either live SARS-CoV-2 particles or retroviruses pseudotyped with the SARS-CoV-2 S viral surface protein(Spike),we studied the neutralizing antibody(nAb)response in serum samples from a cohort of 140 SARS-CoV-2 qPCR-confirmed infections,including patients with mild symptoms and also more severe forms,including those that required intensive care.We show that nAb titers correlated strongly with disease severity and with anti-spike IgG levels.Indeed,patients from intensive care units exhibited high nAb titers;conversely,patients with milder disease symptoms had heterogeneous nAb titers,and asymptomatic or exclusive outpatient-care patients had no or low nAbs.We found that nAb activity in SARS-CoV-2-infected patients displayed a relatively rapid decline after recovery compared to individuals infected with other coronaviruses.Moreover,we found an absence of cross-neutralization between endemic coronaviruses and SARS-CoV-2,indicating that previous infection by human coronaviruses may not generate protective nAbs against SARS-CoV-2.Finally,we found that the D614G mutation in the spike protein,which has recently been identified as the current major variant in Europe,does not allow neutralization escape.Altogether,our results contribute to our understanding of the immune correlates of SARS-CoV-2-induced disease,and rapid evaluation of the role of the humoral response in the pathogenesis of SARS-CoV-2 is warranted. | Vincent Legros Solène Denolly Manon Vogrig Bertrand Boson Eglantine Siret Josselin Rigaill Sylvie Pillet Florence Grattard Sylvie Gonzalo Paul Verhoeven Omran Allatif Philippe Berthelot Carole Pélissier Guillaume Thiery Elisabeth Botelho-Nevers Guillaume Millet Jérôme Morel Stéphane Paul Thierry Walzer François-Loïc Cosset Thomas Bourlet Bruno Pozzetto | 2021 | Cellular & Molecular Immunology2021，18，2： | 3 |
| 16 | Optimal p-Ary Codes from One-Weight and Two-Weight Codes over IF_p+ vIF_p显示文摘This paper is devoted to determining the structures and properties of one-Lee weight codes and two-Lee weight projective codes Ck1,k2,k3 over p IF+ v IFp with type p2k1pk2pk3. The authors introduce a distance-preserving Gray map from( IFp + v IFp)nto2np. By the Gray map, the authors construct a family of optimal one-Hamming weight p-ary linear codes from one-Lee weight codes over IFp+ v IFp, which attain the Plotkin bound and the Griesmer bound. The authors also obtain a class of optimal p-ary linear codes from two-Lee weight projective codes over IFp + vIFp, which meet the Griesmer bound. | SHI Minjia SOL Patrick | 2015 | Journal of Systems Science & Complexity2015，28，3： | 3 |
| 17 | Factors related to quality of life in patients with cirrhosis and ascites: Relevance of serum sodium concentration and leg edema显示文摘 | Elsa Solà Hugh Watson Isabel Graupera Fanny Turón Rogelio Barreto Ezequiel Rodríguez Marco Pavesi Vicente Arroyo Mónica Guevara Pere Ginès | 2012 | Journal of Hepatology2012，，6： | 3 |
| 18 | G2/M inhibitors as pharmacotherapeutic opportunities for glioblastoma:the old,the new,and the future显示文摘Glioblastoma(GBM) is one of the deadliest tumors and has a median survival of 3 months if left untreated. Despite advances in rationally targeted pharmacological approaches, the clinical care of GBM remains palliative in intent. Since the majority of altered signaling cascades involved in cancer establishment and progression eventually affect cell cycle progression, an alternative approach for cancer therapy is to develop innovative compounds that block the activity of crucial molecules needed by tumor cells to complete cell division. In this context, we review promising ongoing and future strategies for GBM therapeutics aimed towards G2/M inhibition such as anti-microtubule agents and targeted therapy against G2/M regulators like cyclin-dependent kinases,Aurora inhibitors, PLK1, BUB, 1, and BUBR1, and survivin. Moreover, we also include investigational agents in the preclinical and early clinical settings. Although several drugs were shown to be gliotoxic, most of them have not yet entered therapeutic trials. The use of either single exposure or a combination with novel compounds may lead to treatment alternatives for GBM patients in the near future. | Angel Mauricio Castro-Gamero Julia Alejandra Pezuk Maria Sol Brassesco Luiz Gonzaga Tone | 2018 | Cancer Biology & Medicine2018，15，4： | 3 |
| 19 | New standard in locally advanced rectal cancer显示文摘In the following review we intend to ascertain the optimal neoadjuvant therapy inpatients with locally advanced rectal cancer. In 2004, a study revealed thatchemoradiotherapy (CRT) resulted in better local control when performedpreoperatively rather than postoperatively, thus neoadjuvant treatment wasestablished as a standard treatment. Subsequently, the Polish study and the Trans-Tasman Radiation Oncology Group showed no statistically significant differencebetween concomitant CRT over 5 wk vs short-course radiotherapy (RT).Therefore, both were established as standard neoadjuvant treatments. Later, theStockholm III study demonstrated that short-course RT had a higher completepathological response than long-course RT. It also showed that a delay betweenRT and surgery presented fewer complications. This opened a window of time toprovide an early and effective systemic treatment to prevent distant metastases.Studies show that short-course RT plus oxaliplatin-based chemotherapy couldachieve this. When comparing this total neoadjuvant treatment (TNT) vsconcomitant CRT, the former showed greater complete pathological response andlower acute toxicity. Studies presented during 2020 have also shown the benefitsof TNT in terms of complete pathological response, as well as disease andmetastasis-free survival. Our review suggests that probably TNT should be thenew standard treatment for these patients. However, we will have to wait for thefull text publications of these studies to confirm this statement. | Sebastián Solé Ramón Baeza Carolina Gabler Felipe Couñago | 2020 | World Journal of Clinical Oncology2020，11，12： | 2 |
| 20 | A pilot trial of fenofibrate for the treatment of non-alcoholic fatty liver disease显示文摘 | C. Fernández-Miranda M. Pérez-Carreras F. Colina G. López-Alonso C. Vargas J.A. Solís-Herruzo | 2007 | Digestive and Liver Disease2007，，3： | 2 |
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