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| 1 | Prognostic factors for transarterial chemoembolization combined with sustained oxaliplatin-based hepatic arterial infusion chemotherapy of colorectal cancer liver metastasis显示文摘Objective: To investigate the prognostic factors in chemorefractory colorectal cancer liver metastasis(CRCLM)patients treated by transarterial chemoembolization(TACE) and sustained hepatic arterial infusion chemotherapy(HAIC).Methods: Between 2006 and 2015, 162 patients who underwent 763 TACE and HAIC in total were enrolled in this retrospective study, including 110 males and 52 females, with a median age of 60(range, 26–83) years.Prognostic factors were assessed with Log-rank test, Cox univariate and multivariate analyses.Results: The median survival time(MST) and median progression-free survival(PFS) of the 162 patients from first TACE/HAIC were 15.6 months and 5.5 months respectively. Normal serum carbohydrate antigen 19-9(CA19-9, <37 U/m L)(P<0.001) and carbohydrate antigen 72-4(CA72-4, <6.7 U/m L)(P=0.026), combination with other local treatment(liver radiotherapy or liver radiofrequency ablation)(P=0.034) and response to TACE/HAIC(P<0.001) were significant factors related to survival after TACE/HAIC in univariate analysis. A multivariate analysis revealed that normal serum CA19-9(P<0.001), response to TACE/HAIC(P<0.001) and combination with other local treatment(P=0.001) were independent factors among them.Conclusions: Our findings indicate that serum CA19-9 <37 U/m L and response to TACE/HAIC are significant prognostic indicators for this combined treatment, and treated with other local treatment could reach a considerable survival benefit for CRCLM. This could be useful for making decisions regarding the treatment of CRCLM. | Hangyu Zhang Jianhai Guo Song Gao Pengjun Zhang Hui Chen Xiaodong Wang Xiaoting Li Xu Zhu | 2017 | Chinese Journal of Cancer Research2017，29，1： | 12 |
| 2 | Anatomic Study of Female Sterility of Pinus tabulaeformis Carr.显示文摘The anatomic research on the mutant clone of Pinus tabulaeformis Carr. in the seed orchard in Xingcheng, LiaoningProvince was carried out. The female cone of the mutant clone looked like normal, but its ovules degenerated in the early stage. Thispaper tries to find out the reason and time of ovule abortion. It seems that the ovule abortion is probably caused by female sterilitybecause the microspores of this mutant clone were normal. Through the serial observations on the one-year-old macrosporangiatesand the ovules of two-year-old female cones of mutant and normal clone, it is found that the reason of ovule abortion in mutant cloneis the failure of the mitosis of free nuclei in the female gametophyte, and the time is about in the early April. | Cheng Pengjun Li Fenglan Zheng CaixiaCollege of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, P. R. China | 2003 | Forestry Studies in China2003，5，1： | 5 |
| 3 | Effect of ALA-PDT on the expressions of MMP-9, MMP-13 and TIMP-1 of hypertrophic scar model in rabbit ears显示文摘Objective: To investigate the effect of 5-aminolevulinic(ALA)-photodynamic therapy(PDT) on the expressions of MMP-9, MMP-13 and TIMP-1 of hypertrophic scar model in rabbit ears, and analyze the possible therapeutic mechanisms of ALA-PDT treatment to hypertrophic scars of rabbit ears. Methods: The experimental animals were randomly divided into normal control, negative control, high concentration of ALA-PDT, low concentration of ALA-PDT and PDT groups. The latter three groups received ALA-PDT treatment or PDT treatment once a week for 3 weeks. The specimens of the rabbits were collected respectively 1, 2 and 3 months after treatment to be used for RT-PCR and Western-blot test. Results: 1, 2 and 3 months after PDT treatment, the expressions of MMP-9 and MMP-13(including mRNA and protein) in hypertrophic scar tissues of three treatment groups were significantly higher than those of the negative control group(P<0.01), and the expression of TIMP-1 mRNA and protein of three treatment groups were significantly lower than that of the negative control group(P<0.01). There were also significant differences between high-concentration ALA-PDT treatment group and the low one(P<0.05). Conclusion: ALA-PDT is effective in treating hypertrophic scars of rabbit ears, and its possible therapeutic mechanisms are that ALA-PDT treatment generates oxidation activation effect to activate the activity of MMPs and induces the photoaging of fibroblasts of hypertrophic scar tissues of rabbit ears to inhibit the activity of TIMPs, which causes the up-regulation of MMPs and the down-regulation of TIMPs. Because of this, the degradation of collagen and ECM is accelerated and the formation of scars is suppressed. | ZHOU Pengjun WANG Qiong LI Zhangjun XIAO Shengxiang XU Lujie | 2013 | Journal of Medical Colleges of PLA(China)2013，28，6： | 2 |
| 4 | Highly Reliable Multiport PUF Circuit Based on MOSFET Zero Temperature Coefficient Point显示文摘By using processing variations in the unitcircuits of the same structures and design parameters during manufacturing, Physical unclonable function(PUF)generates security keys with characteristic of uniqueness,randomness and unclonability. In this paper, a highly reliable multiport PUF scheme was proposed based on MOSFET Zero temperature coefficient(ZTC) point. It consists of input register, deviation-current generating module, arbiter array and obfuscation circuit. After reconfiguring deviation-current generating module by applying different input challenges, the PUF circuit updates keys without physical replacement. And multi-bit keys can be generated in one clock cycle. In TSMC-LP 65 nm CMOS technology, the layout of 64-port reconfigurable PUF occupies 131μm×242μm with custom designing. Experimental results show that the PUF circuit has good statistical characteristic of uniqueness and randomness. It exhibits high reliability of 98.2% with respect to temperature variation from –40℃ to 125℃ and supply voltage variation from 1.08 V to 1.32 V, indicating that it can be reliably and effectively used in information security field. | LI Gang WANG Pengjun QIAN Haoyu | 2018 | Chinese Journal of Electronics2018，27，4： | 2 |
| 5 | Vacancy manipulating of molybdenum carbide MXenes to enhance Faraday reaction for high performance lithium-ion batteries显示文摘“Intrinsic”strategies for manipulating the local electronic structure and coordination environment of defect-regulated materials can optimize electrochemical storage performance.Nevertheless,the structure–activity relationship between defects and charge storage is ambiguous,which may be revealed by constructing highly ordered vacancy structures.Herein,we demonstrate molybdenum carbide MXene nanosheets with customized in-plane chemical ordered vacancies(Mo_(1.33)CT_(x)),by utilizing selective etching strategies.Synchrotron-based X-ray characterizations reveal that Mo atoms in Mo1.33CTx show increased average valence of+4.44 compared with the control Mo_(2)CT_(x).Benefited from the introduced atomic active sites and high valence of Mo,Mo_(1.33)CT_(x)achieves an outstanding capacity of 603 mAh·g^(−1)at 0.2 A·g^(−1),superior to most original MXenes.Li+storage kinetics analysis and density functional theory(DFT)simulations show that this optimized performance ensues from the more charge compensation during charge–discharge process,which enhances Faraday reaction compared with pure Mo_(2)CT_(x).This vacancy manipulation provides an efficient way to realize MXene’s potential as promising electrodes. | Xin Guo Changda Wang Wenjie Wang Quan Zhou Wenjie Xu Pengjun Zhang Shiqiang Wei Yuyang Cao Kefu Zhu Zhanfeng Liu Xiya Yang Yixiu Wang Xiaojun Wu Li Song Shuangming Chen Xiaosong Liu | 2022 | Nano Research Energy2022，1，3： | 2 |
| 6 | Multiplexed cytokine profiling of serum for detection of colorectal cancer显示文摘 | Zhang Pengjun Wen Xinyu Gu Feng Deng Xinxin Liu Yulan Li Juan Jia Xingwang Dong Zhennan Tian Yaping | 2013 | Future Oncol2013，，7： | 2 |
| 7 | Motivating Ru-bri site of RuO_(2)by boron doping toward high performance acidic and neutral oxygen evolution显示文摘The electrocatalysis of oxygen evolution reaction(OER)plays a key role in clean energy storage and transfer.Nonetheless,the sluggish kinetics and poor durability under acidic and neutral conditions severely hinder practical applications such as electrolyzer compatible with the powerful proton exchange membrane and biohybrid fuel production.Here,we report a borondoped ruthenium dioxide electrocatalyst(B-RuO_(2))fabricated by a facile boric acid assisted strategy which demonstrates excellent acidic and neutral OER performances.Density functional theory calculations and advanced characterizations reveal that the boron species form an anomalous B–O covalent bonding with the oxygen atoms of RuO_(2)and expose the fully coordinately bridge ruthenium site(Ru-bri site),which seems like a switch that turns on the inactive Ru-bri site into OER-active,resulting in more exposed active sites,modified electronic structure,and optimized binding energy of intermediates.Thus,the B-RuO_(2)exhibits an ultralow overpotential of 200 mV at 10 mA/cm^(2)and maintains excellent stability compared to commercial RuO_(2)in 0.5 M sulfuric acid.Moreover,the superior performance is as well displayed in neutral electrolyte,surpassing most previously reported catalysts. | Chongjing Liu Beibei Sheng Quan Zhou Dengfeng Cao Honghe Ding Shuangming Chen Pengjun Zhang Yujian Xia Xiaojun Wu Li Song | 2022 | Nano Research2022，15，8： | 1 |
| 8 | In-Situ Synthesis of CQDs/BiOBr Material via Mechanical Ball Milling with Enhanced Photocatalytic Performances显示文摘Designing simple, efficient, and environmentally friendly methods to construct high-efficient photocatalysts is an important strategy to promote the further development of the field of photocatalysis. Herein, flower-like carbon quantum dots(CQDs)/Bi OBr composite photocatalysts have been prepared via in-situ synthesis by mechanical ball milling in the existence of ionic liquid. The CQDs/Bi OBr composites exhibit higher photo-degradation performance for tetracycline(TC) than Bi OBr monomer and the commercial Bi_(2)O_(3) under visible light irradiation. For comparison, the different Br sources and synthetic methods are chosen to prepare Bi OBr and CQDs/Bi OBr composites. Photocatalysts prepared by ball milling and ionic liquid present significantly enhanced photocatalytic performance for removing TC. In addition, the introduction of CQDs could distinctly enhance the photocatalytic performances of pure Bi OBr. The reason is that CQDs as electron acceptor effectively separate electrons and holes and inhibit their recombination. The intermediates during photocatalytic degradation were tested using liquid chromatography-mass spectrometry(LC-MS) and possible degradation pathways were given. During degradation, ·OH, O_(2)^(·-)and h^(+) were identified to be the main active species based on electron spin resonance(ESR) spectra and free radical trapping experiments. A possible mechanism of CQDs/Bi OBr with enhanced photocatalytic performances was further proposed. | Xingwang Yan Bin Wang Mengxia Ji Qi Jiang Gaopeng Liu Pengjun Liu Sheng Yin Huaming Li Jiexiang Xia | 2022 | Chinese Journal of Structural Chemistry2022，41，8： | 1 |
| 9 | Occurrence and impact of polychlorinated dibenzo-p-dioxins/dibenzofurans in the air and soil around a municipal solid waste incinerator显示文摘To assess the influence of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans(PCDD/Fs) on the environment in the vicinity of municipal solid waste incinerators(MSWIs), we determined the levels of PCDD/Fs in air and soil samples collected around a MSWI, which is the largest in China. The International Toxicity Equivalency Quantity(I-TEQ) concentrations of PCDD/Fs in air samples were from 0.0300 to 1.03 pg I-TEQ/m^3(0.445–13.6 pg/m^3), with an average of 0.237 pg I-TEQ/m^3, while in soil samples they ranged from 0.520 to 3.40 pg I-TEQ/g(2.41–88.7 pg/g) with an average of1.49 pg I-TEQ/g. The concentrations of PCDD/Fs in air and soil samples were comparable to other areas, and Pe CDFs were the dominant contributors, which was different from stack gas homologue patterns. Multivariate statistical analysis showed that PCDD/Fs emission from the MSWI did not directly affect the profiles of PCDD/Fs in air and soils, so that vehicles and unidentified emission sources should be considered. The daily inhalation levels of PCDD/Fs for children(0.0110 to 0.392 pg I-TEQ/(kg·day) and adults(0.00600 to 0.221 pg I-TEQ/(kg·day) near the MSWI were lower than the tolerable daily intake of 1.00 to 4.00 pg WHO-TEQ/(kg·day), but in winter the values were higher than in summer. These results can be used as basic data for assessing the risk of PCDD/Fs exposure in residents living around this MSWI, and more monitoring programs and studies should be carried out around MSWIs. | Zhiguang Zhou Yue Ren Jiazhi Chu Nan Li Sen Zhen Hu Zhao Shuang Fan Hui Zhang Pengjun Xu Li Qi Shuting Liang Bin Zhao | 2016 | Journal of Environmental Sciences2016，28，6： | 1 |
| 10 | Molecular cloning and characterization of four heat shock protein genes from Macrocentrus cingulum (Hymenoptera: Braconidae)显示文摘 | Pengjun Xu Jinhua Xiao Li Liu Tong Li Dawei Huang | 2010 | Molecular Biology Reports2010，，5： | 1 |
| 11 | An isolated SNM model for high-stability multi-port register file in 65 nm CMOS显示文摘In modern microprocessors, the multi-port register file is one of the key modules which provides fast and multiple data access for instructions. As the number of access ports in register files increases, stability becomes a key issue due to the voltage fluctuation on bit lines. We propose to apply an isolated inverter to address the voltage fluctuation. To assess the register stability, we derive a closed-form expression of static noise margin(SNM) for our register file. The proposed SNM model can be used as a guideline to predict the impact of several register parameters on the stability and optimize register file designs. To validate the proposed SNM model, we fabricated a test chip of two-write-four-read(2W4R) 1024 bits register file in a TSMC 65 nm low-power CMOS technology.The experimental result shows that the stability of our register file cells with an isolated inverter improve the conventional cells by approximately 2.4 times. Also, the supply voltage causes a fluctuation of SNM of about 65%,while temperature and transistor mismatch cause a fluctuation of SNM of about 20%. | Yuejun Zhang Pengjun Wang Gang Li | 2017 | Journal of Semiconductors2017，38，9： | 1 |
| 12 | Angiotensin1-7 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress by preventing ROS-associated mitochondrial dysfunction and activating the Akt signaling pathway显示文摘 | Pengjun Zhao Fen Li Wei Gao Jing Wang Lijun Fu Yiwei Chen Meirong Huang | 2015 | Acta Histochemica2015，，8： | 1 |
| 13 | Complete Devulcani- zation of Sulfur-Cured Butyl Rubber by Using Supereriti- eal Carbon Dioxide显示文摘 | Jiang Kuan Shi Jinwei Ge Youyong Zou Rui Yao Pengjun Li Xiaolin Zhang LiQun | 2013 | Journal of Apply Polymer Sci- ence2013，，127： | 1 |
| 14 | Efficient aggrega- tion scheduling in multihop wireless sensor networks with SINR con- straints 显示文摘 | Xu Xianhua Li Xiangyang Wang Pengjun | 2013 | IEEE Trans on Mobile Computing2013，12，12： | 1 |
| 15 | Charge density wave phase suppression in 1T-TiSe_(2) through Sn intercalation显示文摘Taking advantage of the unique layered structure of TiSe2,the intrinsic electronic properties of two-dimensional materials can easily be tuned via heteroatomic engineering.Herein,we show that the charge density wave(CDW)phase in 1T-TiSe_(2) single-crystals can be gradually suppressed through Sn atoms intercalation.Using angle-resolved photoemission spectroscopy(ARPES)and temperature-dependent resistivity measurements,this work reveals that Sn atoms can induce charge doping and modulate the intrinsic electronic properties in the host 1T-TiSe_(2).Notably,our temperature-dependent ARPES results highlight the role exciton-phonon interaction and the Jahn-Teller mechanism through the formation of backfolded bands and exhibition of a downward Se shift of 4p valence band in the formation of CDW in this material. | Mukhtar Lawan Adam Hongen Zhu Zhanfeng Liu Shengtao Cui Pengjun Zhang Yi Liu Guobin Zhang Xiaojun Wu Zhe Sun Li Song | 2022 | Nano Research2022，15，3： | 1 |
| 16 | Resilience patterns of human mobility in response to extreme urban floods显示文摘Large-scale disasters can disproportionately impact different population groups,causing prominent disparity and inequality,especially for the vulnerable and marginalized.Here,we investigate the resilience of human mobility under the disturbance of the unprecedented‘720’Zhengzhou flood in China in 2021 using records of 1.32 billion mobile phone signaling generated by 4.35 million people.We find that although pluvial floods can trigger mobility reductions,the overall structural dynamics of mobility networks remain relatively stable.We also find that the low levels of mobility resilience in female,adolescent and older adult groups are mainly due to their insufficient capabilities to maintain business-as-usual travel frequency during the flood.Most importantly,we reveal three types of counter-intuitive,yet widely existing,resilience patterns of human mobility(namely,‘reverse bathtub’,‘ever-increasing’and‘ever-decreasing’patterns),and demonstrate a universal mechanism of disaster-avoidance response by further corroborating that those abnormal resilience patterns are not associated with people’s gender or age.In view of the common association between travel behaviors and travelers’socio-demographic characteristics,our findings provide a caveat for scholars when disclosing disparities in human travel behaviors during flood-induced emergencies. | Junqing Tang Pengjun Zhao Zhaoya Gong Hongbo Zhao Fengjue Huang Jiaying Li Zhihe Chen Ling Yu Jun Chen | 2023 | National Science Review2023，10，8： | 1 |
| 17 | Design of a DTCTGAL circuit and its application显示文摘 | Wang Pengjun Li Kunpeng Mei Fengna | 2009 | Chinese Journal of Semi- conductors2009，30，11： | 1 |
| 18 | Complete devulcanization of sulfur‐cured butyl rubber by using supercritical carbon dioxide显示文摘 | Kuan Jiang Jinwei Shi Youyong Ge Rui Zou Pengjun Yao Xiaolin Li Liqun Zhang | 2012 | J Appl Polym Sci2012，，4： | 1 |
| 19 | Cloning, expression, and characterization of a new xylanase with broad temperature adaptability from Streptomyces sp. S9显示文摘 | Ning Li Kun Meng Yaru Wang Pengjun Shi Huiying Luo Yingguo Bai Peilong Yang Bin Yao | 2008 | Applied Microbiology and Biotechnology2008，，2： | 1 |
| 20 | Coverage in wireless adHoc sensor networks显示文摘 | XIANGYANG LI PENGJUN WAN OPHIR FRIEDER | 2003 | IEEE Transactions on Computer(SO018-9340)2003，52，6： | 1 |
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