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| 1 | Strata movement controlling effect of waste and fly ash backfillings in fully mechanized coal mining with backfilling face显示文摘A fully mechanized coal mining with backfilling (FMCMB) provides advantages of safety and efficiency for coal mining under buildings, railways, and water bodies. According to the field geological conditions, we analyzed the controlling effect of strata movement by the waste and fly ash backfilling in FMCMB face. Based on the key strata theory, we established the equivalent mining thickness model, and analyzed the action of the bulk factor of backfilling body to the equivalent mining thickness. In addition, we numerically simulated the controlling function of the strata movement by backfilling bodies with differ- ent strength. And the numerical simulation result show that the deformation of stratum and the subsi- dence of surface can be controlled by FMCMB. The result provides references to the effective execution of fully mechanized coal mining with solid waste backfilling in goaf. | Zhang Jixiong Zhang Qiang Huang Yanli Liu Jinwei Zhou Nan Zan Dongfeng | 2011 | Mining Science and Technology2011，21，5： | 27 |
| 2 | Perspectives on studies on soil carbon stocks and the carbon sequestration potential of China显示文摘Soil carbon stocks and sequestration have been given a lot of attention recently in the study of terrestrial ecosystems and global climate change.This review focuses on the progress made on the estimation of the soil carbon stocks of China,and the characterization of carbon dynamics of croplands with regard to climate change,and addresses issues on the mineralization of soil organic carbon in relation to greenhouse gas emissions.By integrating existing research data,China's total soil organic carbon(SOC) stock is estimated to be 90 Pg and its inorganic carbon(SIC) stock as 60 Pg,with SOC sequestration rates in the range of 20-25 Tg/a for the last two decades.An estimation of the biophysical potential of SOC sequestration has been generally agreed as being 2 Pg over the long term,of which only 1/3 could be attainable using contemporary agricultural technologies in all of China's croplands.Thus,it is critical to enhance SOC sequestration and mitigate climate change to improve agricultural and land use management in China.There have been many instances where SOC accumulation may not induce an increased amount of decomposition under a warming scenario but instead favor improved cropland productivity and ecosystem functioning.Furthermore,unchanged or even decreased net global warming potential(GWP) from croplands with enhanced SOC has been reported by a number of case studies using life cycle analysis.Future studies on soil carbon stocks and the sequestration potential of China are expected to focus on:(1) Carbon stocks and the sequestration capacity of the earths' surface systems at scales ranging from the plot to the watershed and(2) multiple interface processes and the synergies between carbon sequestration and ecosystem productivity and ecosystem functioning at scales from the molecular level to agro-ecosystems.Soil carbon science in China faces new challenges and opportunities to undertake integrated research applicable to many areas. | ZHENG JuFeng CHENG Kun PAN GenXing Pete SMITH LI LianQing ZHANG XuHui ZHENG JinWei HAN XiaoJun DU YanLing | 2011 | Chinese Science Bulletin2011，56，35： | 24 |
| 3 | Cropland redistribution to marginal lands undermines environmental sustainability显示文摘Cropland redistribution to marginal land has been reported worldwide;however,the resulting impacts on environmental sustainability have not been investigated sufficiently.Here we investigated the environmental impacts of cropland redistribution in China.As a result of urbanization-induced loss of high-quality croplands in south China(~8.5 t ha^(-1)),croplands expanded to marginal lands in northeast(~4.5 t ha^(-1)) and northwest China(~2.9 t ha^(-1)) during 1990-2015 to pursue food security.However,the reclamation in these low-yield and ecologically vulnerable zones considerably undermined local environmental sustainability,for example increasing wind erosion(+3.47%),irrigation water consumption(+34.42%),fertilizer use(+20.02%) and decreasing natural habitats(-3.11%).Forecasts show that further reclamation in marginal lands per current policies would exacerbate environmental costs by 2050.The future cropland security risk will be remarkably intensified because of the conflict between food production and environmental sustainability.Our research suggests that globally emerging reclamation of marginal lands should be restricted and crop yield boost should be encouraged for both food security and environmental benefits. | Wenhui Kuang Jiyuan Liu Hanqin Tian Hao Shi Jinwei Dong Changqing Song Xiaoyong Li Guoming Du Yali Hou Dengsheng Lu Wenfeng Chi Tao Pan Shuwen Zhang Rafiq Hamdi Zherui Yin Huimin Yan Changzhen Yan Shixin Wu Rendong Li Jiuchun Yang Yinyin Dou Wenbin Wu Liqiao Liang Bao Xiang Shiqi Yang | 2022 | National Science Review2022，9，1： | 13 |
| 4 | Continuous land cover change monitoring in the remote sensing big data era显示文摘Since the late 20th century,global change issues have attracted lots of attention.As a key component of global changes,land cover and land use information has been increasingly important for improved understanding of global environmental changes and feedbacks between social and environmental systems(Verburg et al.,2015).A set of national and global scale land cover/use products with higher spatial and temporal resolutions have been developed to fill this gap.In China,existing efforts include China’s | DONG JinWei KUANG WenHui LIU JiYuan | 2017 | Science China Earth Sciences2017，60，12： | 13 |
| 5 | Cenozoic Adakite-type Volcanic Rocks in Qiangtang,Tibet and Its Significance显示文摘Volcanic rocks in the study area, including dacite, trachyandesite and mugearite, belong to the intermediate-acid, high-K calc-alkaline series, and possess the characteristics of adakite. The geochemistry of the rocks shows that therocks are characterized by SiO2>59%, enrichment in Al2O3 (15.09-15.64%) and Na2O (>3.6%), high Sr (649-885 μg/g)and Sc, low Y contents (<17 μg/g), depletion in HREE (Yb<1.22 μg/g), (La/Yb)N>25, Sr/Y>40, MgO<3% (Mg#<0.35),weak Eu anomaly (Eu/Eu*=0.84-0.94), and lack of the high field strength elements (HFSE) (Nb, Ta, Ti, etc.). The Nd andSr isotope data (87Sr/86Sr=0.7062-0.7079, 143Nd/144Nd=0.51166-0.51253, εNd= -18.61-0.02), show that the magmaresulted from partial melting (10%-40%) of newly underplated basaltic lower crust under high pressure (1-4 GPa), and thepetrogenesis is obviously affected by the crust's assimilation and fractional crystallization (AFC). This research will givean insight into the uplift mechanism of the Tibetan plateau. | LIUShen HURuizhong FENGCaixia CHIXiaoguo LICai YANGRihong WANGTianwu JINWei | 2003 | Acta Geologica Sinica(English Edition)2003，77，2： | 11 |
| 6 | Study on stabilities and electrochemical behavior of V(V) electrolyte with acid additives for vanadium redox flow battery显示文摘Several acid compounds have been employed as additives of the V(V) electrolyte for vanadium redox flow battery(VRB) to improve its stability and electrochemical activity. Stability of the V(V) electrolyte with and without additives was investigated with ex-situ heating/cooling treatment at a wide temperature range of-5 ?C to 60 ?C. It was observed that methanesulfonic acid, boric acid, hydrochloric acid, trifluoroacetic acid,polyacrylic acid, oxalic acid, methacrylic acid and phosphotungstic acid could improve the stability of the V(V) electrolyte at a certain range of temperature. Their electrochemical behaviors in the V(V) electrolyte were further studied by cyclic voltammetry(CV), steady state polarization and electrochemical impedance spectroscopy(EIS). The results showed that the electrochemical activity, including the reversibility of electrode reaction, the diffusivity of V(V) species, the polarization resistance and the flexibility of charge transfer for the V(V) electrolyte with these additives were all improved compared with the pristine solution. | Gang Wang Jinwei Chen Xueqin Wang Jing Tian Hong Kang Xuejing Zhu Yu Zhang Xiaojiang Liu Ruilin Wang | 2014 | Journal of Energy Chemistry2014，23，1： | 10 |
| 7 | Petrogenetic differences between the Middle-Late Jurassic Cu-Pb-Zn-bearing and W-bearing granites in the Nanling Range,South China: A case study of the Tongshanling and Weijia deposits in southern Hunan Province显示文摘The Middle-Late Jurassic Cu-Pb-Zn-bearing and W-bearing granites in the Nanling Range have distinctly different mineralogical and geochemical signatures. The Cu-Pb-Zn-bearing granites are dominated by metaluminous amphibole-bearing granodiorites, which have higher CaO/(Na2O+K2O) ratios, light/heavy rare earth element(LREE/HREE) ratios, and δEu values,lower Rb/Sr ratios, and weak Ba, Sr, P, and Ti depletions, exhibiting low degrees of fractionation. The W-bearing granites are highly differentiated and peraluminous, and they have lower CaO/(Na2O+K2O) ratios, LREE/HREE ratios, and δEu values,higher Rb/Sr ratios, and strong Ba, Sr, P, and Ti depletions. The Cu-Pb-Zn-bearing granites were formed predominantly between155.2 and 167.0 Ma with a peak value of 160.6 Ma, whereas the W-bearing granites were formed mainly from 151.1 to 161.8Ma with a peak value of 155.5 Ma. There is a time gap of about 5 Ma between the two different types of ore-bearing granites.Based on detailed geochronological and geochemical studies of both the Tongshanling Cu-Pb-Zn-bearing and Weijia W-bearing granites in southern Hunan Province and combined with the other Middle-Late Jurassic Cu-Pb-Zn-bearing and W-bearing granites in the Nanling Range, a genetic model of the two different types of ore-bearing granites has been proposed. Asthenosphere upwelling and basaltic magma underplating were induced by the subduction of the palaeo-Pacific plate. The underplated basaltic magmas provided heat to cause a partial melting of the mafic amphibolitic basement in the lower crust, resulting in the formation of Cu-Pb-Zn mineralization related granodioritic magmas. With the development of basaltic magma underplating,the muscovite-rich metasedimentary basement in the upper-middle crust was partially melted to generate W-bearing granitic magmas. The compositional difference of granite sources accounted for the metallogenic specialization, and the non-simultaneous partial melting of one source followed by the other brought about a time gap of about 5 Ma between the Cu-Pb-Zn-bearing and W-bearing granites. | HUANG XuDong LU JianJun Stanislas SIZARET WANG RuCheng MA DongSheng ZHANG RongQing ZHAO Xu WU JinWei | 2017 | Science China Earth Sciences2017，60，7： | 9 |
| 8 | Paleoclimate Changes during the Early Oligocene in the Hoh Xil Region, Northern Tibetan Plateau显示文摘Sedimentological, cyclic-stratigraphic, paleomagnetic, and clay-mineralogical studies on the early Oligocene Yaxicuo Group in the Hoh Xil Basin, the largest Cenozoic sedimentary basin in the hinterland of the Tibetan Plateau, provide abundant information of paleoclimate changes. A 350-m thick section in the middle-lower Yaxicuo Group was analyzed to reveal the climatic history that occurred in the Hoh Xil region during the early Oligocene interval 31.30-30.35 Ma, dated with the paleomagnetic chronostratigraphy. The results indicate that add and cold climate dominated the Hoh Xil region during the early Oligocene in general, being related to the global cooling and drying events that occurred in the earliest Oligocene. Within this period, relatively warm and wet climate accompanied by strong tectonic activity occurred in the 31.05-30.75 Ma interval; while add and cold climate and relatively inactive tectonics occurred in the 31.30-31.05 and 30.75-30.35 Ma intervals. Furthermore, spectral analyses of high-temporal resolution paleoclimatic records show orbital periods including eccentricity, obliquity, and precession. It is concluded that paleoclimate changes during the early Oligocene in the Hoh Xil region were forced by both tectonic activity and orbital periods. | LIUZhifei WANGChengshan AlainTRENTESAUX ZHAOXixi YIHaisheng HUXiumian JINWei | 2003 | Acta Geologica Sinica(English Edition)2003，77，4： | 8 |
| 9 | Variations of Vegetation Phenology Extracted from Remote Sensing Data over the Tibetan Plateau Hinterland during 2000–2014显示文摘How vegetation phenology responds to climate change is a key to the understanding of the mechanisms driving historic and future changes in regional terrestrial ecosystem productivity. Based on the 250-m and 8-day moderate resolution imaging spectroradiometer(MODIS) normalized difference vegetation index(NDVI) data for 2000-2014 in the Three-River Source Region(TRSR) of Qinghai Province, China, i.e., the hinterland of the Tibetan Plateau, we extracted relevant vegetation phenological information(e.g., start, end, and length of growing season) and analyzed the changes in the TRSR vegetation in response to climate change. The results reveal that, under the increasingly warm and humid climate, the start of vegetation growing season(SOS) advanced 1.03 day yr-1 while the end of vegetation growing season(EOS) exhibited no significant changes, which led to extended growing season length. It is found that the SOS was greatly affected by the preceding winter precipitation, with progressively enhanced precipitation facilitating an earlier SOS. Moreover, as the variations of SOS and its trend depended strongly on topography, we estimated the elevation break-points for SOS. The lower the elevations were, the earlier the SOS started. In the areas below 3095-m elevation, the SOS delay changed rapidly with increasing elevation;whereas above that, the SOS changes were relatively minor. The SOS trend had three elevation break-points at 2660, 3880, and 5240 m. | Ya LIU Junbang WANG Jinwei DONG Shaoqiang WANG Hui YE | 2020 | Journal of Meteorological Research2020，34，4： | 8 |
| 10 | Fingered Intrusion of Shallow Saucer-shaped Igneous Sills: Insights from the Jiaojiang Sag, East China Sea显示文摘An extensive suite of igneous sills was intruded into the Tertiary sedimentary section of the Jiaojiang sag,East China Sea.This suite has been well imaged offshore through 2D and 3D seismic surveys,showing a close relationship with CO2 content in nearby gas discoveries.A new observational model,which incorporates simple upward propagation,simple horizontal propagation,and transgressive propagation,was proposed to interpret these sill intrusions.In this model,the source magma of the saucer-shaped sills was injected from their lowest points near the center.The transgressive propagation can be interpreted as a combination of the vertical and horizontal propagation.Most shallow sub-volcanic intrusions in the Jiaojiang sag exhibit fingered characteristics,both vertically and horizontally.The vertical fingered propagation produced saucer-shaped sills arranged in the flower style.Along the brims of lower sills could usually be found the upper sills,which are interpreted to have formed simultaneously with or later than the lower feeder sills.In the second type,the chilled paths of the older sills were reutilized by subsequent intrusions.The horizontal fingered propagation formed sheet intrusions that exhibit groove,lobate,tubular,and crevasse splaylike geometry in plan view.In 3D view,the sheet intrusions have still preserved the lower center and higher rim that similar with the sub-rounded saucer-shaped sills.Although fracture propagation may be important,flow inflation was the key mechanism of magma intrusion.Further consideration of the mechanisms underlying sill formation may help explain the fingered characteristics of sill propagation. | GUO Rui ZHANG Gongcheng ZHANG Jinwei ZHAO Xingbin LIU Junbang YUAN Dawei SONG Shuang | 2013 | Acta Geologica Sinica(English Edition)2013，87，5： | 8 |
| 11 | The Late Pleistocene activity of the eastern part of east Kunlun fault zone and its tectonic significance显示文摘The nearly EW-trending East Kunlun fault zone is the north boundary of the Bayan Har block.The activity characteristics and the position of the eastern end of its eastward extension are of great significance to probing into the dynamic mechanism of formation of the east edge of the Tibetan Plateau,and also lay the foundation for seismic risk assessment of the fault zone.The following results are obtained by analysis based on satellite image interpretation of landforms,surface rupture survey,terrace scarp deformation survey,and terrace dating data on the eastern part of the East Kunlun fault zone:(1)the Luocha segment is a Holocene active fault,where a reverse L-shape paleoearthquake surface rupture zone of about 50 km long is located;(2)the Luocha segment is characterized by left-lateral slip movement under the compression-shear condition since the later period of the Late Pleistocene,with a rate of 7.68–9.37 mm/a and a vertical slip rate of 0.7–0.9 mm/a,which are basically in accord with the activity rate of segments on its west side.The results indicate that it is a part of eastward extension of the East Kunlun fault zone;(3)the high-speed linear horizontal slip of the nearly EW-trending East Kunlun fault zone is blocked by the South China block at east,and transforms into the vertical movement of the nearly SN-NNE trending Minjiang fault zone and the Longmenshan fault zone,and the uplift of Longmenshan and Minjiang.The area where transform of the two tectonic systems occurred confines the position of the east end;(4)Luocha segment and Maqu segment constitute the'Maqu seismic gap',so,seismic risk at Maqu segment is higher than that at Luocha segment,which should attract more attention. | ZHANG JunLong REN JinWei CHEN ChangYun FU JunDong YANG PanXin XIONG RenWei HU ChaoZhong | 2014 | Science China Earth Sciences2014，57，3： | 8 |
| 12 | Impacts of ecological restoration projects on agricultural productivity in China显示文摘在农田数量和质量的变化由于陆地使用是国家食物安全的批评担心,特别地为中国。尽管有重要生态的效果,生态的恢复节目(ERP ) ,从 1999 开始了,显然改变了瓷器农田和农业生产率的空间模式。从 2000 ~ 2008 把动态数据基于农田首先与主要生产率建模的 30-m 分辨率和基于卫星的网源于卫星图象,我们在 ERP 引起的农业生产率上识别了影响,包括为格林的谷物,节目(GFGP ) 和到湖(RCTL ) 的回收农田编程序。我们的结果显示农业生产率与 132.67lis 的率输了。在 R 的射击的 Pb 的累积。pseudoacacia 比另外的种类显著地高。在学习区域的土壤的 Pb 的数量是 s 吗?? | QIN Yuanwei YAN Huimin LIU Jiyuan DONG Jinwei CHEN Jingqing XIAO Xiangming | 2013 | Journal of Geographical Sciences2013，23，3： | 8 |
| 13 | Photodegradation mechanism of deltamethrin and fenvalerate显示文摘To understand the degradation and environmental fate of pyrethroids,the process of their photodegradation under simulated natural conditions was investigated.The results showed that the degradation process follows first-order kinetics.The degradation intermediates were identified with gas chromatography-mass spectrometry.A plausible mechanism was discussed to explain the process.Several influences on degradation process were investigated and reported such as the effects of initial concentration of pyrethroids,total time of light irradiation,solvents,and light source,as well as the effect of a few substances that exist in the environment.This study could be a good reference for the degradation of pyrethroids in practical circumstances. | Pengyan Liu Yujie Liu Qingxue Liu Jinwei Liu | 2010 | Journal of Environmental Sciences2010，22，7： | 8 |
| 14 | Design and analysis of a truss deployable antenna mechanism based on a 3UU-3URU unit显示文摘Space deployable structures with large calibers, high accuracy, and large folding ratios are indispensable equipment in the aerospace field. Given that the single-DOF 3 RR-3 RRR deployable unit cannot be fully folded, this study proposes a 3 UU-3 URU deployable unit with two kinds of DOF: folding movement and orientation adjustment. First, based on the G-K formula, the DOF of the 3 UU-3 URU unit is analyzed. Then, the 3 UU-3 URU unit is used to construct a deployable truss antenna with a curved surface, and the DOF of the whole deployable antenna containing multiple 3 UU-3 URU units is calculated. The structural design of a deployable antenna with two loops is carried out with specific parameters and geometric relations. Next, a DOF simulation of a basic combination unit composed of three 3 UU-3 URU units is performed. Finally, a prototype of the basic combination unit is manufactured, and the DOF of the mechanism is experimentally verified. | Yundou XU Jinwei GUO Luyao GUO Wenlan LIU Jiantao YAO Yongsheng ZHAO | 2019 | Chinese Journal of Aeronautics2019，32，12： | 7 |
| 15 | Recent developments in electrocatalysts and future prospects for oxygen reduction reaction in polymer electrolyte membrane fuel cells显示文摘The main difficulty in the extensive commercial use of polymer electrolyte membrane fuel cells(PEMFCs)is the use of noble metals such as Pt-based electrocatalyst at the cathode, which is essential to ease the oxygen reduction reaction(ORR) in fuel cells(FCs). To eliminate the high loading of Pt-based electrocatalysts to minimize the cost, extensive study has been carried out over the previous decades on the non-noble metal catalysts. Development in enhancing the ORR performance of FCs is mainly due to the doped carbon materials, Fe and Co-based electrocatalysts, these materials could be considered as probable substitutes for Pt-based catalysts. But the stability of these non-noble metal electrocatalysts is low and the durability of these metals remains unclear. The three basic reasons of instability are:(i) oxidative occurrence by H_2O_2,(ii) leakage of the metal site and(iii) protonation by probable anion adsorption of the active site. Whereas leakage of the metal site has been almost solved, more work is required to understand and avoid losses from oxidative attack and protonation. The ORR performance such as stability tests are usually run at low current densities and the lifetime is much shorter than desired need. Therefore,improvement in the ORR activity and stability are the key issues of the non-noble metal electrocatalyst.Based on the consequences obtained in this area, numerous future research directions are projected and discussed in this paper. Hence, this review is focused on improvement of stability and durability of the non-noble metal electrocatalyst. | Maryam Kiani Jie Zhang Yan Luo Chunping Jiang Jinlong Fan Gang Wang Jinwei Chen Ruilin Wang | 2018 | Journal of Energy Chemistry2018，27，4： | 7 |
| 16 | In-situ sulfur isotope and trace element of pyrite constraints on the formation and evolution of the Nibao Carlin-type gold deposit in SW China显示文摘The fault-controlled Nibao Carlin-type gold deposit,together with the strata-bound Shuiyindong deposit,comprise a significant amount of the disseminated gold deposits in southwestern Guizhou Province,China.Five main types and two sub-types of pyrite at the Nibao deposit(Py1a/Py1b,Py2,Py3,Py4,Py5)were distinguished based on detailed mineralogical work.Py1,Py2and Py3 are Au-poor,whereas Py4 and Py5 are Au-rich,corresponding to a sedimentary and hydrothermal origin,respectively.Through systematic in situ analyses of NanoSIMS sulfur isotopes,the framboid pyrite Py1a with negative δ^34S values(-53.3 to-14.9%)from the Nibao deposit were found to originate from bacterial sulfate reduction(BSR)processes in an open and sulfate-sufficient condition while the superheavy pyrite Py1b(73.7–114.8%)is probably due to the potential influence of closed-system Rayleigh fractionation or the lack of preservation of deepsea sediments.Data of Py2 and Py3 plot within the area of S isotope compositions from biogenic and abiogenic sulfate reduction.In view of few coeval magmatic rocks in the mining district,the near zero δ^34S values of the Au-rich pyrites(Py4 and Py5)may discount the potential involvement of magmatic but metamorphic or sedimentary origin.LA-ICP-MS and TEM work show that Au in ore-related pyrite is present as both nanoparticles and structurally bound.LA-ICP-MS analyses show that the Au-rich pyrite also contains higher As,Cu,Sb,Tl and S than other types of pyrite,which inferred a distal manifestation of deep hydrothermal mineralization systems. | Jinxiang Li Chenghai Zhao Yong Huang Yuzhou Zhuo Jinwei Li | 2019 | Acta Geochimica2019，38，4： | 7 |
| 17 | Prevalence and treatment of hypertension in China: impacts of 2017 American College of Cardiology/American Heart Association High Blood Pressure Guideline显示文摘The definition, recommended treatment thresholds and targets of hypertension have been updated in the recent 2017 American College of Cardiology/American Heart Association(ACC/AHA) Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults. However,the impacts of this guideline on Chinese population are currently unknown. In this study, we aim to provide updated data in China using criteria from the updated guideline. A multistage, stratified sampling method was used to obtain a representative sample of 50,171 adults aged 18 years and above.Hypertension was defined as an average systolic blood pressure !130 mm Hg, or an average diastolic blood pressure !80 mm Hg, or self-reported use of antihypertensive medications in past 2 weeks. The weighted prevalence of hypertension was 60.1%(95% confidence interval [CI] 59.3%–61.0%). The treatment rate and recommended treatment rate were 16.8%(95% CI 16.1%–17.6%) and 53.7%(95% CI52.6%–54.9%), respectively; the gap was more prominent among men and participants from rural areas.Hence, the adoption of the 2017 ACC/AHA guideline will lead to a substantial increase in both prevalence and number of patients needing treatment in China. The applicability of this guideline should be carefully evaluated based on evidence from Chinese population. | Chao Yang Jinwei Wang Bixia Gao Yan Zhang Fang Wang Luxia Zhang Minghui Zhao Yong Huo | 2018 | Science Bulletin2018，63，8： | 7 |
| 18 | Regulatory control of the Na-Cl co-transporter NCC and its therapeutic potential for hypertension显示文摘Hypertension is the largest risk factor for cardiovascular disease,the leading cause of mortality worldwide.As blood pressure regulation is influenced by multiple physiological systems,hypertension cannot be attributed to a single identifiable etiology.Three decades of research into Mendelian forms of hypertension implicated alterations in the renal tubular sodium handling,particularly the distal convoluted tubule(DCT)-native,thiazide-sensitive Na-Cl cotransporter(NCC).Altered functions of the NCC have shown to have profound effects on blood pressure regulation as illustrated by the over activation and inactivation of the NCC in Gordon’s and Gitelman syndromes respectively.Substantial progress has uncovered multiple factors that affect the expression and activity of the NCC.In particular,NCC activity is controlled by phosphorylation/dephosphorylation,and NCC expression is facilitated by glycosylation and negatively regulated by ubiquitination.Studies have even found parvalbumin to be an unexpected regulator of the NCC.In recent years,there have been considerable advances in our understanding of NCC control mechanisms,particularly via the pathway containing the with-no-lysine[K](WNK)and its downstream target kinases,SPS/Ste20-related proline-alanine-rich kinase(SPAK)and oxidative stress responsive 1(OSR1),which has led to the discovery of novel inhibitory molecules.This review summarizes the currently reported regulatory mechanisms of the NCC and discusses their potential as therapeutic targets for treating hypertension. | Nur Farah Meor Azlan Maarten P.Koeners Jinwei Zhang | 2021 | Acta Pharmaceutica Sinica B2021，11，5： | 6 |
| 19 | Transgenic breeding of anti-Bombyx mori L. nuclear polyhedrosis virus silkworm Bombyx mori显示文摘对 Bombyx 粗腐殖质 i L 抵抗的蚕紧张。原子 polyhedrosis 病毒通过转基因的实验被获得。与一个 A3 倡导者一起的小猪用绳子拖的平底渡船 transposon 随机被插入到蚕,驾驶进蚕染色体的提高的绿荧光灯的蛋白质(EGFP ) 记者基因。聚合酶链反应结果证实体外的 EGFP 基因的插入,和荧光显微镜学证明 EGFP 在中间的内脏织物被表示。原子 polyhedrosis 的病态比率在转基因的蚕紧张在原来的蚕紧张从 90% 减少了到 66.7% 。与到 Bombyx 粗腐殖质 i L 的抵抗相比。在 Qiufeng 紧张的原子 polyhedrosis 病毒,通常在生产被使用,有在转基因的蚕的 33 个百分的点的增加。在 ChunhuaxQiuyue 紧张的 antivirotic 特性,从一个不同转基因的家庭被引起,比在 QiufengxBaiyu,另一个生气品种在生产使用了高是大约 10 个百分的点。我们的结果在繁殖 anti-BmNPV 蚕紧张显示了插入 transposon 的变化的好申请价值。 | Huijuan Yang Wei Fan Hao Wei Jinwei Zhang Zhonghua Zhou Jianying Li Jianrong Lin Nong Ding Boxiong Zhong | 2008 | Acta Biochimica et Biophysica Sinica2008，40，10： | 6 |
| 20 | Microstructure and Mechanical Properties of Electron Beam Welded Titanium Alloy Ti-6246显示文摘Electron beam welding(EBW) was applied to a 10-mm-thick plate cut from Ti-6246 compressor disk.The microstructural characteristics, microhardness and room temperature tensile properties were investigated. Microstructure observations indicated that there existed plenty of thin needle-like α platelets studding in the matrix of the columnar β grains in the as-welded fusion zone(FZ). Post-weld heat treatment(PWHT) led to the precipitation of small secondary α platelets in the β matrix in heat affected zone and FZ. The thickness and the density of α platelets increased as the temperature of PWHT increased from545 to 645°C. The microhardness across the Ti-6246 EBW joint exhibited a nonuniform distribution. The hardness increased with the decrease of distance to the weld center, and reached the maximum of 467 HV in FZ when PWHT was carried out at 595°C. All the weldments tested with tension were fractured at the base material(BM) and exhibited a ductile fracture mode. The major deformation barrier in BM was the platelet α/β interfaces, however, the major deformation barrier in FZ was found to be β grain boundaries and secondary α/β interfaces. The BM with thicker platelet α phases had lower strength than the other two zones in the joint, and the BM deformed first and led to fracture in this zone. | Guoqiang Wang Zhiyong Chen Jinwei Li Jianrong Liu Qingjiang Wang Rui Yang | 2018 | Journal of Materials Science & Technology2018，34，3： | 6 |
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