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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017,27,12: | 70 |
| 2 | Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China显示文摘The H5N8 avian influenza viruses have been widely circulating in wild birds and are responsible for the loss of over 33 million domestic poultry in Europe, Russia, Middle East, and Asia since January 2020. To monitor the invasion and spread of the H5N8 virus in China, we performed active surveillance by analyzing 317 wild bird samples and swab samples collected from 41,172 poultry all over the country. We isolated 22 H5N8 viruses from wild birds and 14 H5N8 viruses from waterfowls. Genetic analysis indicated that the 36 viruses formed two different genotypes: one genotype viruses were widely detected from different wild birds and domestic waterfowls;the other genotype was isolated from a whopper swan. We further revealed the origin and spatiotemporal spread of these two distinct H5N8 virus genotypes in 2020 and 2021. Animal studies indicated that the H5N8 isolates are highly pathogenic to chickens, mildly pathogenic in ducks, but have distinct pathotypes in mice. Moreover, we found that vaccinated poultry in China could be completely protected against H5N8 virus challenge. Given that the H5N8 viruses are likely to continue to spread in wild birds, vaccination of poultry is highly recommended in high-risk countries to prevent H5N8 avian influenza. | Pengfei Cui Xianying Zeng Xuyong Li Yanbing Li Jianzhong Shi Conghui Zhao Zhiyuan Qu Yanwen Wang Jing Guo Wenli Gu Qi Ma Yuancheng Zhang Weipeng Lin Minghui Li Jingman Tian Dongxue Wang Xin Xing Yanjing Liu Shuxin Pan Yaping Zhang Hongmei Bao Liling Liu Guobin Tian Chengjun Li Guohua Deng Hualan Chen | 2022 | Science China(Life Sciences)2022,65,4: | 12 |
| 3 | Experimental study of rotating gliding arc discharge plasma-assisted combustion in an aero-engine combustion chamber显示文摘The combustion chamber is the core component of an aero-engine, and affects its reliability and security operation, even the performance of the aircraft. In this work, a Plasma-Assisted Combustion(PAC) test platform was developed to validate the feasibility of using PAC actuators to enhance annular combustor performance. Two plans of PAC(rotating gliding arc discharge plasma) were designed, Assisted Combustion from Primary Holes(ACPH) and Assisted Combustion from Dilution Holes(ACDH). Comparative experiments and analysis between conventional combustion and PAC were conducted to study the effects of ACPH and ACDH on the performances including average outlet temperature, combustion efficiency, pattern factor under four different excessive air coefficients(0.8, 1, 2, and 4), and lean blowout performance at different inlet airflow velocities. Experimental results show that the combustion efficiency is improved after PAC compared with that in normal conditions, and the combustion efficiency of ACPH increases2.45%, 1.49%, 1.04%, and 0.47%, while it increases 2.75%, 1.67%, 1.36%, and 0.36% under ACDH conditions. The uniformity of the outlet temperature field and the lean blowout performance are improved after PAC. Especially for ACPH, the widening of the lean blowout limit is8.3%, 12.4%, 12.8%, and 25% respectively when the inlet velocity ranges from 60 m/s to120 m/s. These results offer new perspectives for using PAC devices to enhance aero-engine combustors' performances. | Liming HE Yi CHEN Jun DENG Jianping LEI Li FEI Pengfei LIU | 2019 | Chinese Journal of Aeronautics2019,32,2: | 8 |
| 4 | Insights from avian influenza surveillance of chickens and ducks before and after exposure to live poultry markets显示文摘Dear Editor, Live poultry markets are the major trading system of poultry in China and many other countries, and are also thought to be important for the generation and spread of avian influenza viruses and other avian pathogens (Zhang et al., 2013;Shi et al., 2017;Quan et al., 2018). | Mei Li Xin Yin Lizheng Guan Xia Zhang Guohua Deng Tao Li Pengfei Cui Yong Ma Yujie Hou Jianzhong Shi Hualan Chen | 2019 | Science China(Life Sciences)2019,62,6: | 6 |
| 5 | Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer显示文摘Metformin is currently a strong candidate anti-tumor agent in multiple cancers.However,its anti-tumor effectiveness varies among different cancers or sub-populations,potentially due to tumor heterogeneity.It thus remains unclear which hepatocellular carcinoma(HCC)patient subpopulation(s)can benefit from met-formin treatment.Here,through a genome-wide CRISPR-Cas9-based knockout screen,we find that DOCK1 levels determine the anti-tumor effects of met-formin and that DOCK1 is a synthetic lethal target of metformin in HCC.Mechanistically,metformin promotes DOCK1 phosphorylation,which activates RAC1 to facilitate cell survival,leading to metformin resistance.The DOCK1-selective inhibitor,TBOPP,potentiates anti-tumor activity by metformin in vitro in liver cancer cell lines and patient-derived HCC organoids,and in vivo in xenografted liver cancer cells and immunocompetent mouse liver cancer models.Notably,metformin improves overall survival of HCC patients with low DOCK1 levels but not among patients with high DOCK1 expression.This study shows that metformin effective-ness depends on DOCK1 levels and that combining metformin with DOCK1 inhibition may provide a promising personalized therapeutic strategy for met-formin-resistant HCC patients. | Junru Feng Hui Lu Wenhao Ma Wenjing Tian Zhuan Lu Hongying Yang Yongping Cai Pengfei Cai Yuchen Sun Zilong Zhou Jiaqian Feng Jiazhong Deng Ying Shu Kun Qu Weidong Jia Ping Gao Huafeng Zhang | 2022 | Protein & Cell2022,13,11: | 5 |
| 6 | A potential red-emitting phosphor Ca_(2)YTaO_(6):Eu^(3+):Luminescence properties,thermal stability and applications for white LEDs显示文摘A novel red-emitting phosphor tantalate Ca_(2)YTaO_(6):Eu^(3+)was synthesized by a solid-state reaction.The purity and surface morphology of the phosphors were characterized.The Ca_(2)YTaO_(6):Eu^(3+)phosphors show a sharp emission peak at 612 nm under near-ultraviolet(n-UV) at 395 nm because of the ^(5)D0→^(7)F_(2) transition of Eu^(3+).The optimal Eu^(3+)doping concentration in Ca_(2)YTaO_(6) is 40 mol% and the critical energy-transfer distance of Eu^(3+)ions was calculated to be 0.9 nm.The emission spectra of Ca_(2)YTaO_(6):Eu_(3+)from 300 to 480 K were investigated.The thermal-quenching temperature(T_(0.5)) of Ca_(2)YTaO_(6):Eu^(3+)is above 480 K.The color purity of Ca_(2)YTaO_(6):40 mol%Eu^(3+)is as high as 99.8%.The luminescence lifetime of Ca_(2)YTaO_(6):40 mol%Eu^(3+)was also discussed.The high color purity and high thermal stability of Eu^(3+)-doped Ca_(2)YTaO_(6) phosphors contribute to its application value in white lightemitting diodes(w-LEDs). | Ka Ding Siru A Shuo Pang Leyan Shan Yaqi Zhang Pengfei Sun Bin Deng Ruijin Yu | 2021 | Journal of Rare Earths2021,39,7: | 4 |
| 7 | ALM1, encoding a Fe-superoxide dismutase, is critical for rice chloroplast biogenesis and drought stress response显示文摘Chloroplasts are the center of plant life activities including photosynthesis,growth and development,and abiotic stress response.Chloroplast development and biogenesis in rice have been studied in detail,but how does abiotic stress affect chloroplasts is less studied.We obtained an albino mutant,alm1,whose chlorophyll content was greatly decreased.Transmission electron microscopy showed that chloroplast development in alm1 was blocked,especially in thylakoid-like structures,which could not form normally.The ALM1 gene encodes a chloroplast-localized superoxide dismutase.Full-length ALM1 successfully restored the non-albino phenotype,and in knockout lines,the albino phenotype reappeared.The ALM1gene is expressed mainly in young leaves.alm1 plants died as a consequence of excessive reactive oxygen accumulation after the third-leaf stage.A series of biochemical assays verified that ALM1 interacted with the OsTrxz protein,which is one of the components of plastid-encoded RNA polymerase (PEP) complexes.A western blot experiment indicated that ALM1 played an important role in stabilizing OsTrxz in rice.An overexpression test of ALM1 revealed that ALM1 can increase drought resistance by removing excess reactive oxygen in rice seedlings.This study suggests that ALM1 not only participates in rice chloroplast biogenesis,but also increases rice stress resistance by scavenging excess reactive oxygen. | Yanwei Wang Chen Deng Pengfei Ai Xue’an Cui Zhiguo Zhang | 2021 | The Crop Journal2021,9,5: | 4 |
| 8 | Frontiers in circularly polarized luminescence:molecular design,self-assembly,nanomaterials,and applications显示文摘The research in circularly polarized luminescence has attracted wide interest in recent years.Efforts on one side are directed toward the development of chiral materials with both high luminescence efficiency and dissymmetry factors,and on the other side,are focused on the exploitations of these materials in optoelectronic applications.This review summarizes the recent frontiers(mostly within five years)in the research in circularly polarized luminescence,including the development of chiral emissive materials based on organic small molecules,compounds with aggregation-induced emissions,supramolecular assemblies,liquid crystals and liquids,polymers,metal-ligand coordination complexes and assemblies,metal clusters,inorganic nanomaterials,and photon upconversion systems.In addition,recent applications of related materials in organic light-emitting devices,circularly polarized light detectors,and organic lasers and displays are also discussed. | Zhong-Liang Gong Xuefeng Zhu Zhonghao Zhou Si-Wei Zhang Dong Yang Biao Zhao Yi-Pin Zhang Jianping Deng Yixiang Cheng You-Xuan Zheng Shuang-Quan Zang Hua Kuang Pengfei Duan Mingjian Yuan Chuan-Feng Chen Yong Sheng Zhao Yu-Wu Zhong Ben Zhong Tang Minghua Liu | 2021 | Science China Chemistry2021,64,12: | 3 |
| 9 | Where do flare ribbons stop?显示文摘The standard flare model,which was proposed based on observations and magnetohydrodynamic theory,can successfully explain many observational features of solar flares.However,this model is just a framework,with many details awaiting to be filled in, including how reconnection is triggered.In this paper,we address an unanswered question:where do flare ribbons stop?With the data analysis of the 2003 May 29 flare event,we tentatively confirmed our conjecture that flare ribbons finally stop at the intersection of separatrices(or quasi-separatrix layer in a general case)with the solar surface.Once verified,such a conjecture can be used to predict the final size and even the lifetime of solar flares. | CHEN PengFei SU JiangTao GUO Yan DENG YuanYong | 2012 | Chinese Science Bulletin2012,57,12: | 2 |
| 10 | Bismuth doped lead-free two-dimensional tin based halide perovskite single crystals显示文摘Heterovalent-metal doping is an efficient tool to tune the optoelectronic properties of the famous halide perovskites.Previous studies have focused on the heterovalent-doping in three-dimensional(3D) halide perovskites.However, there is a lack of such doping in two-dimensional perovskites which possess unique optoelectronic properties and improved chemical stability as compared to 3D analogues.Here, we present successful doping of Bismuth into the lattice of lead-free, two-dimensional perovskite PEA2SnBr4 single crystals.Structural characterizations demonstrate that the doped crystals possess identical crystal structure and layered morphology with the pristine one.Intriguingly, we find the PL peak and spectral shape can be tailored by tuning the concentration of Bi dopants.Femtosecond transient absorption spectroscopy is performed to understand the underlying mechanism related to tunable PL behaviors, and a clear picture of the Bismuth-doping impact is provided. | Ruiling Zhang Xin Mao Pengfei Cheng Yang Yang Songqiu Yang Tuerdi Wumaier Weiqiao Deng Keli Han | 2019 | Journal of Energy Chemistry2019,28,9: | 2 |
| 11 | Application of electrochemical depassivation in PRB systems to recovery Fe^0 reactivity显示文摘 | Xin LU Miao LI Hao DENG Pengfei LIN Mark R. MATSUMOTO Xiang LIU | 2016 | Frontiers of Environmental Science & Engineering2016,10,4: | 2 |
| 12 | β-tricalcium phosphate nanoparticles adhered carbon nanofibrous membrane for human osteoblasts cell culture显示文摘 | Haiyang Liu Qing Cai Pengfei Lian Zhou Fang Shun Duan Xiaoping Yang Xuliang Deng Seungkon Ryu | 2010 | Materials Letters2010,,6: | 1 |
| 13 | Probing the active sites of 2D nanosheets with Fe-N-C carbon shell encapsulated Fe_(x)C/Fe species for boosting sodium-ion storage performances显示文摘Developing stable but high active metal-nitrogen-carbon(M-N-C)-based hard carbon anode is a promising way to be the alternatives to graphene and blank hard carbon for sodium-ion batteries(SIBs),requiring the precise tailoring of the electronic structure for optimizing the Na+intercalation behavior,yet is greatly challenging.Herein,Fe-N-C graphitic layer-encapsulating Fe3C species within hard carbon nanosheets(Fe-N-C/Fe3C@HCNs)are rationally engineered by pyrolysis of self-assembled polymer.Impressively,the Fe-N-C/Fe3C@HCNs exhibit outstanding rate capacity(242 mAh·g^(−1)at 2,000 mA·g^(−1)),which is 2.1 and 4.2 times higher than that of Fe-N-C and N-doped carbon(N-C),respectively,and prolonged cycling stability(176 mAh·g^(−1)at 2,000 mA·g^(−1)after 2,000 cycles).Theoretical calculations unveil that the Fe3C species enhance the electronic transfer from Na to Fe-N-C,resulting in the charge redistribution between the interfaces of Fe3C and Fe-N-C.Thus,the optimized adsorption behavior towards Na+reduces the thermodynamic energy barriers.The synergistic effect of Fe3C and Fe-N-C species maintains the structural integrity of electrode materials during the sodiation/desodiation process.The in-depth insight into the advanced Na+storage mechanisms of Fe3C@Fe-N-C offers precise guidance for the rational establishment of confinement heterostructures in SIBs. | Huicong Xia Pengfei Yuan Lingxing Zan Gan Qu Yunchuan Tu Kaixin Zhu Yifan Wei Zeyu WeiFangying Zheng Mo Zhang Yongfeng Hu Dehui Deng Jianan Zhang | 2022 | Nano Research2022,15,8: | 1 |
| 14 | GLOBAL SMOOTH SOLUTIONS FOR SEMILINEAR SCHRDINGER EQUATIONS WITH BOUNDARY FEEDBACK ON 2-DIMENSIONAL RIEMANNIAN MANIFOLDS显示文摘当起始的数据是小的时,这篇论文在 2-dimensional Riemannian manifolds 上与边界反馈认为半的全球光滑的解决方案的存在是线性 schrödinger 方程。作者证明全球答案的存在边界反馈取决于不仅,而且在一个 Riemannian 度量标准上,由原则部分和原来的度量标准的系数给歧管。特别地, authers 证明系统的精力指数地腐烂。 | Li DENG Pengfei YAO | 2009 | Journal of Systems Science & Complexity2009,22,4: | 1 |
| 15 | Efficient enantioselective synthesis of CF_(2)Hcontaining dispiro[benzo[b]thiophene-oxindolepyrrolidine]s via organocatalytic cycloaddition显示文摘An efficient and practical organocatalytic asymmetric[3+2]cycloaddition of difluoromethylated ketoimines and methyleneindolinones catalyzed by a quinine-derived squaramide has been disclosed.Under mild conditions,a broad range of CF_(2)H-containing dispiro[benzo[b]thiophene-oxindole-pyrrolidine]s bearing four adjacent chiral centers including two vicinal spiro quaternary stereocenters were obtained in high yields(up to 99%yield)with excellent diastereoselectivities(>20:1 dr,in all cases)and enantioselectivities(up to 99%ee). | Yabo Deng Yongzhen Li Yalan Wang Shuo Sun Sichao Ma Pengfei Jia Wenguang Li Kairong Wang Wenjin Yan | 2022 | Organic Chemistry Frontiers2022,9,1: | 1 |
| 16 | Parallel design of convolutional neural networks for remote sensing images object recognition based on data-driven array processor显示文摘Object recognition in very high-resolution remote sensing images is a basic problem in the field of aerial and satellite image analysis.With the development of sensor technology and aerospace remote sensing technology,the quality and quantity of remote sensing images are improved.Traditional recognition methods have a certain limitation in describing higher-level features,but object recognition method based on convolutional neural network(CNN)can not only deal with large scale images,but also train features automatically with high efficiency.It is mainly used on object recognition for remote sensing images.In this paper,an AlexNet CNN model is trained using 2100 remote sensing images,and correction rate can reach 97.6%after 2000 iterations.Then based on trained model,a parallel design of CNN for remote sensing images object recognition based on data-driven array processor(DDAP)is proposed.The consuming cycles are counted.Simultaneously,the proposed architecture is realized on Xilinx V6 development board,and synthesized based on SMIC 130 nm complementary metal oxid semiconductor(CMOS)technology.The experimental results show that the proposed architecture has a certain degree of parallelism to achieve the purpose of accelerating calculations. | Shan Rui Jiang Lin Deng Junyong Cui Pengfei Zhang Yuting Wu Haoyue Xie Xiaoyan | 2020 | The Journal of China Universities of Posts and Telecommunications2020,27,6: | 1 |
| 17 | Effect of surface modifica- tion on the electrochemical performances of LaNi5 hydrogen stor- age alloy in Ni/MH batteries 显示文摘 | Deng Chao Shi Pengfei Zhang Sen | 2006 | Materials Chemistry and Phys- ics2006,98,23: | 1 |
| 18 | J pH- Temperature Responsive Poly (HPA-CO-AMHS) Hydrogel as A Potential Drug-Release Carrier显示文摘 | Deng Kuilin Tian Hua Zhang Pengfei | 2009 | Journal of Applied Polymer Science2009,114,: | 1 |
| 19 | Engineering white blood cell membrane-camouflaged nanocarriers for inflammation-related therapeutics显示文摘White blood cells(WBCs)play essential roles against inflammatory disorders,bacterial infections,and cancers.Inspired by nature,WBC membrane-camouflaged nanocarriers(WBC-NCs)have been developed to mimic the“dynamic”functions of WBCs,such as transendothelial migration,adhesion to injured blood vessels,etc,which make them promising for diverse medical applications.WBC-NCs inherit the cell membrane antigens of WBCs,while still exhibiting the robust inflammation-related therapeutic potential of synthetic nanocarriers with excellent(bio)physicochemical performance.This review summarizes the proposed concept of cell membrane engineering,which utilizes physical engineering,chemical modification,and biological functionalization technologies to endow the natural cell membrane with abundant functionalities.In addition,it highlights the recent progress and applications of WBC-NCs for inflammation targeting,biological neutralization,and immune modulation.Finally,the challenges and opportunities in realizing the full potential of WBC-NCs for the manipulation of inflammation-related therapeutics are discussed. | Wanli Song Pengfei Jia Yaping Ren Junmiao Xue Bingqian Zhou Xinkai Xu Yansheng Shan Jing Deng Qihui Zhou | 2023 | Bioactive Materials2023,,5: | 1 |
| 20 | Pt/3D-graphene/FTO electrodes: Electrochemical preparation and their enhanced electrocatalytic activity显示文摘 | Shaolin Yang Yongwei Huang Wei Zhu Bingchen Deng Hong Wang Zihan Zhang Pengfei Bao Guanzhong Wang | 2014 | International Journal of Hydrogen Energy2014,,27: | 1 |