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| 1 | Myeloid-specific targeting of Notch ameliorates murine renal fibrosis via reduced infiltration and activation of bone marrowderived macrophage显示文摘Macrophages play critical roles in renal fibrosis.However,macrophages exhibit ontogenic and functional heterogeneities,and which population of macrophages contributes to renal fibrosis and the underlying mechanisms remain unclear.In this study,we genetically targeted Notch signaling by disrupting the transcription factor recombination signal binding protein-JK(RBP-J),to reveal its role in regulation of macrophages during the unilateral ureteral obstruction(UUO)-induced murine renal fibrosis.Myeloid-specific disruption of RBP-J attenuated renal fibrosis with reduced extracellular matrix deposition and myofibroblast activation,as well as attenuated epithelial-mesenchymal transition,likely owing to the reduced expression of TGF-β.Mean while,RBP-J deletion significantly hampered macrophage infiltration and activation in fibrotic kidney,although their proliferation appeared unaltered.By using macrophage clearance experiment,we found that kidney resident macrophages made negligible contribution,but bone marrow(BM)-derived macrophages played a major role in renal fibrogenesis.Further mechanistic analyses showed that Notch blockade reduced monocyte emigration from BM by down-regulating CCR2 expression.Finally,we found that myeloid-specific Notch activation aggravated renal fibrosis,which was mediated by CCR2^+macrophages infiltration.In summary,our data have unveiled that myeloid-specific targeting of Notch could ameliorate renal fibrosis by regulating BM-derived macrophages recruitment and activation,providing a novel strategy for intervention of this disease. | Yali Jiang Yuanyuan Wang Pengfei Ma Dongjie An Junlong Zhao Shiqian Liang Yuchen Ye Yingying Lu Peng Zhang Xiaowei Liu Hua Han Hongyan Qin | 2019 | Protein & Cell2019，10，3： | 10 |
| 2 | Deep-learning-based phase control method for tiled aperture coherent beam combining systems显示文摘We incorporate deep learning(DL)into tiled aperture coherent beam combining(CBC)systems for the first time,to the best of our knowledge.By using a well-trained convolutional neural network DL model,which has been constructed at a non-focal-plane to avoid the data collision problem,the relative phase of each beamlet could be accurately estimated,and then the phase error in the CBC system could be compensated directly by a servo phase control system.The feasibility and extensibility of the phase control method have been demonstrated by simulating the coherent combining of different hexagonal arrays.This DL-based phase control method offers a new way of eliminating dynamic phase noise in tiled aperture CBC systems,and it could provide a valuable reference on alleviating the long-standing problem that the phase control bandwidth decreases as the number of array elements increases. | Tianyue Hou Yi An Qi Chang Pengfei Ma Jun Li Dong Zhi Liangjin Huang Rongtao Su Jian Wu Yanxing Ma Pu Zhou | 2019 | High Power Laser Science and Engineering2019，7，4： | 10 |
| 3 | Three-dimensional porous V2O5 hierarchical octahedrons with adjustable pore architectures for long-life lithium batteries显示文摘三维(3D ) 多孔的 V < 潜水艇 class= “ a-plus-plus ” > 2 O < 潜水艇 class= “ a-plus-plus ” > 5 八面体成功地被制作了经由一固态刚准备的铵钒氧化物(AVO ) 的变换过程八面体。AVO 八面体的形成是盖住试剂和生长种类的赞成过度饱和的选择吸附的结果。随后, 3D 多孔的 V < 潜水艇 class= “ a-plus-plus ” > 2 O < 潜水艇 class= “ a-plus-plus ” > 5 八面体被 AVO 八面体的简单 thermolysis 经由一个锻烧处理获得。作为为锂电池的阴极材料,多孔的 V < 潜水艇 class= “ a-plus-plus ” > 2 O < 潜水艇 class= “ a-plus-plus ” > 5 八面体阴极在西班牙的北方展出 96 mAsga 盆的一个能力;并且(3 ) Zpy (n ?=? 17 ) , LV 质量从 226 被减少[178;306 ] g 到 220 [169;254 ] g (p ?=? 0.007 ) 在 13 点 ? 桴 ? 畦摮浡湥慴? 牦煥敵据敩 ? 景琠敨猠摥浩湥獴? 敢楳敤琠敨氠湯楧畴楤慮? 湡 ? 牴湡癳牥敳映湵慤敭瑮污映敲畱湥楣獥漠 ? 慥档戠極摬湩 ? 慢敳 ? 湯琠敨愠灭楬畴敤猠数瑣慲愠摮琠敨映潬牯猠数瑣慲? 慲楴?? 剓? 敭桴摯? | Qinyou An Pengfei Zhang Fangyu Xiong Qiulong Wei Jinzhi Sheng Qinqin Wang Liqiang Mai | 2015 | Nano Research2015，8，2： | 9 |
| 4 | Deep-learning-assisted, two-stage phase control method for high-power mode-programmable orbital angular momentum beam generation显示文摘High-power mode-programmable orbital angular momentum(OAM)beams have received substantial attention in recent years.They are widely used in optical communication,nonlinear frequency conversion,and laser processing.To overcome the power limitation of a single beam,coherent beam combining(CBC)of laser arrays is used.However,in specific CBC systems used to generate structured light with a complex wavefront,eliminating phase noise and realizing flexible phase modulation proved to be difficult challenges.In this paper,we propose and demonstrate a two-stage phase control method that can generate OAM beams with different topological charges from a CBC system.During the phase control process,the phase errors are preliminarily compensated by a deep-learning(DL)network,and further eliminated by an optimization algorithm.Moreover,by modulating the expected relative phase vector and cost function,all-electronic flexible programmable switching of the OAM mode is realized.Results indicate that the proposed method combines the characteristics of DL for undesired convergent phase avoidance and the advantages of the optimization algorithm for accuracy improvement,thereby ensuring the high mode purity of the generated OAM beams.This work could provide a valuable reference for future implementation of high-power,fast switchable structured light generation and manipulation. | TIANYUE HOU YI AN QI CHANG PENGFEI MA JUN LI LIANGJIN HUANG DONG ZHI JIAN WU RONGTAO SU YANXING MA PU ZHOU | 2020 | Photonics Research2020，8，5： | 8 |
| 5 | The Chinese Hα Solar Explorer(CHASE) mission: An overview显示文摘The Chinese Hα Solar Explorer(CHASE), dubbed “Xihe”—Goddess of the Sun, was launched on October 14, 2021 as the first solar space mission of China National Space Administration(CNSA). The CHASE mission is designed to test a newly developed satellite platform and to acquire the spectroscopic observations in the Hα waveband. The Hα Imaging Spectrograph(HIS)is the scientific payload of the CHASE satellite. It consists of two observational modes: raster scanning mode and continuum imaging mode. The raster scanning mode obtains full-Sun or region-of-interest spectral images from 6559.7 to 6565.9 ? and from 6567.8 to 6570.6 ? with 0.024 ? pixel spectral resolution and 1 min temporal resolution. The continuum imaging mode obtains photospheric images in continuum around 6689 ? with the full width at half maximum of 13.4 ?. The CHASE mission will advance our understanding of the dynamics of solar activity in the photosphere and chromosphere. In this paper, we present an overview of the CHASE mission including the scientific objectives, HIS instrument overview, data calibration flow, and first results of on-orbit observations. | Chuan Li Cheng Fang Zhen Li MingDe Ding PengFei Chen Ye Qiu Wei You Yuan Yuan MinJie An HongJiang Tao XianSheng Li Zhe Chen Qiang Liu Gui Mei Liang Yang Wei Zhang WeiQiang Cheng JianXin Chen ChangYa Chen Qiang Gu QingLong Huang MingXing Liu ChengShan Han HongWei Xin ChangZheng Chen YiWei Ni WenBo Wang ShiHao Rao HaiTang Li Xi Lu Wei Wang Jun Lin YiXian Jiang LingJie Meng Jian Zhao | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 7 |
| 6 | Metastable amorphous chromium-vanadium oxide nanoparticles with superior performance as a new lithium battery cathode显示文摘钒氧化物的主要缺点作为阴极材料是它的低传导性,低实际能力和差的骑车稳定性。补充说 Cr 能改进它的传导性和一个亚稳的非结晶的状态可以提供更高的能力和稳定性。在这个工作,亚稳的非结晶的 Cr-V-O nanoparticles 成功地通过反应由退火跟随了的灵巧的一起沉淀被准备了处理。作为为锂电池的阴极材料,亚稳的非结晶的 Cr-V-O nanoparticles 展览高度能力(在在 1.54 V 之间的 100 mA/g 的 260 mAh/g ) ,低能力损失(超过 80% 在 100 mA/g 在 200 个周期以后被保留) 并且高率能力(多达 3 A/g ) 。 | Jinzhi Sheng Qidong Li Qiulong Wei Pengfei Zhang Qinqin Wang Fan Lv Qinyou An Wei Chen Liqiang Mai | 2014 | Nano Research2014，7，11： | 5 |
| 7 | ALM1, encoding a Fe-superoxide dismutase, is critical for rice chloroplast biogenesis and drought stress response显示文摘Chloroplasts are the center of plant life activities including photosynthesis,growth and development,and abiotic stress response.Chloroplast development and biogenesis in rice have been studied in detail,but how does abiotic stress affect chloroplasts is less studied.We obtained an albino mutant,alm1,whose chlorophyll content was greatly decreased.Transmission electron microscopy showed that chloroplast development in alm1 was blocked,especially in thylakoid-like structures,which could not form normally.The ALM1 gene encodes a chloroplast-localized superoxide dismutase.Full-length ALM1 successfully restored the non-albino phenotype,and in knockout lines,the albino phenotype reappeared.The ALM1gene is expressed mainly in young leaves.alm1 plants died as a consequence of excessive reactive oxygen accumulation after the third-leaf stage.A series of biochemical assays verified that ALM1 interacted with the OsTrxz protein,which is one of the components of plastid-encoded RNA polymerase (PEP) complexes.A western blot experiment indicated that ALM1 played an important role in stabilizing OsTrxz in rice.An overexpression test of ALM1 revealed that ALM1 can increase drought resistance by removing excess reactive oxygen in rice seedlings.This study suggests that ALM1 not only participates in rice chloroplast biogenesis,but also increases rice stress resistance by scavenging excess reactive oxygen. | Yanwei Wang Chen Deng Pengfei Ai Xue’an Cui Zhiguo Zhang | 2021 | The Crop Journal2021，9，5： | 4 |
| 8 | Simulation and Improvements of Oceanic Circulation and Sea Ice by the Coupled Climate System Model FGOALS-f3-L显示文摘This study documents simulated oceanic circulations and sea ice by the coupled climate system model FGOALS-f3-L developed at the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics,Institute of Atmospheric Physics,Chinese Academy of Sciences,under historical forcing from phase 6 of the Coupled Model Intercomparison Project(CMIP6).FGOALS-f3-L reproduces the fundamental features of global oceanic circulations,such as sea surface temperature(SST),sea surface salinity(SSS),mixed layer depth(MLD),vertical temperature and salinity,and meridional overturning circulations.There are notable improvements compared with the previous version,FGOALS-s2,such as a reduction in warm SST biases near the western and eastern boundaries of oceans and salty SSS biases in the tropical western Atlantic and eastern boundaries,and a mitigation of deep MLD biases at high latitudes.However,several obvious biases remain.The most significant biases include cold SST biases in the northwestern Pacific(over 4°C),freshwater SSS biases and deep MLD biases in the subtropics,and temperature and salinity biases in deep ocean at high latitudes.The simulated sea ice shows a reasonable distribution but stronger seasonal cycle than observed.The spatial patterns of sea ice are more realistic in FGOALS-f3-L than its previous version because the latitude–longitude grid is replaced with a tripolar grid in the ocean and sea ice model.The most significant biases are the overestimated sea ice and underestimated SSS in the Labrador Sea and Barents Sea,which are related to the shallower MLD and weaker vertical mixing. | Yuyang GUO Yongqiang YU Pengfei LIN Hailong LIU Bian HE Qing BAO Bo AN Shuwen ZHAO and Lijuan HUA | 2020 | Advances in Atmospheric Sciences2020，37，10： | 3 |
| 9 | Recent advances of carbon dots as new antimicrobial agents显示文摘Due to the COVID-19 pandemic,many rapid antimicrobial agents have developed intensively.Carbon dots(CDs),a new type of carbon-based nanomaterials,shows great potential against emerging infectious diseases and antimicrobial-resistant infections due to their unique optical properties,excellent biocompatibility,and easy surface modification.With the definition of the CDs structure and properties,synthesis,and characteristic technology improvement,the research on the CDs as antimicrobial agents has made significant progress.However,the lack of high repeatable and exact preparation methods,and the regular antimicrobial activity make it far from practical application.In this review,we summarize the most recent progress and challenges of CDs antimicrobial.First,an overview of the characteristics and properties is given,and the advantage of CDs applied to antimicrobial is further discussed.Then,it focuses on research progress on antimicrobial mechanisms under different conditions,the critical factors affecting their antimicrobial activity,and the practical antimicrobial applications.Finally,the main challenges and future research perspectives of antimicrobial CDs are proposed. | Pengfei Li Lu Sun Shanshan Xue Dan Qu Li An Xiayan Wang Zaicheng Sun | 2022 | SmartMat2022，3，2： | 3 |
| 10 | Relationship between hyperlipidemia and the gut microbiome of rats, characterized using high-throughput sequencing显示文摘Objective:To determine the effects of a high-fat diet(HFD)on the gut microbiome in rats,to explore the relationship between the intestinal flora and blood lipid profile.Methods:SpragueeDawley rats were fed an HFD for four weeks to induce hyperlipidemia,then 16S rRNA sequencing was used to compare the intestinal flora between hyperlipidemic and control diet-fed rats.Results:The microbiome of rats fed an HFD for four weeks differed from that of control diet-fed rats.Bacterial species that were less abundant were most affected by HFD feeding,among which were many pathogenic species,which became significantly more abundant.Eighteen genera were present in significantly different numbers in hyperlipidemic and control rats,more than half of which have been linked to infection and inflammation,or energy intake and obesity.The results indicated a type of stress response of the flora to a high-fat environment.In addition,the age of the rats tended to influence the gut microbial composition.Conclusion:These findings suggest that HFD may induce hyperlipidemia by affecting the gut microbial composition.Changes in the abundance of pro-inflammatory and pathogenic bacteria,and those that influence energy intake and obesity,may be important mediators of this. | Yaqi Li Quantao Ma Jingkang Wang Pengfei Li Long Cheng Yongcheng An Yuhui Duan Hongyu Dai Ting Wang Baosheng Zhao | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，2： | 3 |
| 11 | Carbohydrate-based drugs launched during 2000-2021显示文摘Carbohydrates are fundamental molecules involved in nearly all aspects of lives,such as being involved in formating the genetic and energy materials,supporting the structure of organisms,constituting invasion and host defense systems,and forming antibiotics secondary metabolites.The naturally occurring carbohydrates and their derivatives have been extensively studied as therapeutic agents for the treatment of various diseases.During 2000 to 2021,totally 54 carbohydrate-based drugs which contain carbohydrate moities as the major structural units have been approved as drugs or diagnostic agents.Here we provide a comprehensive review on the chemical structures,activities,and clinical trial results of these carbohydrate-based drugs,which are categorized by their indications into antiviral drugs,antibacterial/antiparasitic drugs,anticancer drugs,antidiabetics drugs,cardiovascular drugs,nervous system drugs,and other agents. | Xin Cao Xiaojing Du Heng Jiao Quanlin An Ruoxue Chen Pengfei Fang Jing Wang Biao Yu | 2022 | Acta Pharmaceutica Sinica B2022，12，10： | 1 |
| 12 | Studies on the surface modification of diatomite with polyethyleneimine and trapping effect of the modified diatomite for phenol显示文摘 | Baojiao Gao Pengfei Jiang Fuqiang An Shuying Zhao Zhen Ge | 2005 | Applied Surface Science2005，250，14： | 1 |
| 13 | Stuendies on the surface modification of diatomite with polyethyleneimine and trapping effect of the modified diatomite for phenol 显示文摘 | GAO Baojiao JIANG Pengfei AN Fuqiang | 2005 | Applied Surface Science2005，250，3： | 1 |
| 14 | Single site catalyst with enzyme-mimic micro-environment for electroreduction of CO_(2)显示文摘Single site catalysts provide a unique platform for mimicking natural enzyme due to their tunable interaction between metal center and coordinated ligand.However,most works have focused on preparing structural and functional models of nature enzyme,with less reports also taking the local chemical environment,i.e.,functional/catalytic residues around the active site which is an essential feature of enzymes,into consideration.Herein,we report a Co-centered porphyrinic polymer containing the enzyme-mimic micro-environment,where the linker triazole over CoN4 site enables formation of hydrogen bond with the*COOH intermediate,thus promoting the electrocatalytic reduction of CO_(2).As-prepared catalyst achieves the CO_(2)-to-CO conversion of 5,788 h^(−1) turnover frequency value and near unit(~96%)faradaic efficiency at−0.61 V versus reversible hydrogen electrode.This strategy will bring new dimension of designing highly active single-site catalysts. | Chang Long Kaiwei Wan Xueying Qiu Xiaofei Zhang Jianyu Han Pengfei An Zhongjie Yang Xiang Li Jun Guo Xinghua Shi Hui Wang Zhiyong Tang Shaoqin Liu | 2022 | Nano Research2022，15，3： | 1 |
| 15 | Downhole Microseismic Source Location Based on a Multi-Dimensional DIRECT Algorithm for Unconventional Oil and Gas Reservoir Exploration显示文摘Downhole microseismic data has the significant advantages of high signal-to-noise ratio and well-developed P and S waves and the core component of microseismic monitoring is microseismic event location associated with hydraulic fracturing in a relatively high confidence level and accuracy.In this study,we present a multidimensional DIRECT inversion method for microseismic locations and applicability tests over modeling data based on a downhole microseismic monitoring system.Synthetic tests inidcate that the objective function of locations can be defined as a multi-dimensional matrix space by employing the global optimization DIRECT algorithm,because it can be run without the initial value and objective function derivation,and the discretely scattered objective points lead to an expeditious contraction of objective functions in each dimension.This study shows that the DIRECT algorithm can be extensively applied in real downhole microseismic monitoring data from hydraulic fracturing completions.Therefore,the methodology,based on a multidimensional DIRECT algorithm,can provide significant high accuracy and convergent efficiency as well as robust computation for interpretable spatiotemporal microseismic evolution,which is more suitable for real-time processing of a large amount of downhole microseismic monitoring data. | YIN Qifeng TAO Pengfei ZHENG Shuo HE Qing AN Yanfei GUO Quanshi | 2019 | Acta Geologica Sinica(English Edition)2019，93，3： | 1 |
| 16 | SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR显示文摘Farnesoid X receptor(FXR)is widely accepted as a promising target for various liver diseases;however,panels of ligands in drug development show limited clinical benefits,without a clear mechanism.Here,we reveal that acetylation initiates and orchestrates FXR nucleocytoplasmic shuttling and then enhances degradation by the cytosolic E3 ligase CHIP under conditions of liver injury,which represents the major culprit that limits the clinical benefits of FXR agonists against liver diseases.Upon inflammatory and apoptotic stimulation,enhanced FXR acetylation at K217,closed to the nuclear location signal,blocks its recognition by importin KPNA3,thereby preventing its nuclear import.Concomitantly,reduced phosphorylation at T442 within the nuclear export signals promotes its recognition by exportin CRM1,and thereby facilitating FXR export to the cytosol.Acetylation governs nucleocytoplasmic shuttling of FXR,resulting in enhanced cytosolic retention of FXR that is amenable to degradation by CHIP.SIRT1 activators reduce FXR acetylation and prevent its cytosolic degradation.More importantly,SIRT1 activators synergize with FXR agonists in combating acute and chronic liver injuries.In conclusion,these findings innovate a promising strategy to develop therapeutics against liver diseases by combining SIRT1 activators and FXR agonists. | Shuang Cui Huijian Hu An Chen Ming Cui Xiaojie Pan Pengfei Zhang Guangji Wang Hong Wang Haiping Hao | 2023 | Acta Pharmaceutica Sinica B2023，13，2： | 1 |
| 17 | Greatly enhanced electro-optic modulation efficiency in titanium in-diffusion PIN-PMN-PT waveguide显示文摘Electro-optic modulators,which convert electrical signals onto the transmission light,are key devices in electro-optic modulating systems.Modulation efficiency is one of the most important parameters of an electro-optic modulator,which directly determines the footprint and power consumption of the device.Generally,modulation efficiency strongly depends on the electro-optic response of the crystal.The Pb(In_(1/2)Nb_(1/2))O_(3)-Pb(Mg_(1/3)Nb_(2/3))O_(3)-PbTiO_(3)(PIN-PMN-PT)single crystal with giant electro-optic coefficient(λ_(c))and high transparency indicates the potential to achieve greatly enhanced modulation efficiency.In this study,a prototype PIN-PMN-PT phase modulator was fabricated based on a titanium(Ti)in-diffusion waveguide,which is reported for the first time.The influences of titanium in-diffusion on the composition and domain structure of the PIN-PMN-PT single crystal were studied by transmission electron microscopy(TEM)and piezoelectric force microscopy(PFM),respectively.Finally,a half-wave voltage(V_(π))of 2.3 V was obtained using a device with 6-mm-long(L)electrodes.Furthermore,the electro-optic modulation efficiency(V_(π)L)was calculated as 1.38 V-cm,which was approximately one order of magnitude lower than that of commercial lithium niobate(LiNbO_(3),LN)phase modulators.Such enhanced modulation efficiency indicates more compact device and lower power consumption,which is of great significance for electro-optic modulation systems used in micro-fiber gyroscope,integrated photonic devices,etc. | Qingyuan Hu Yuebin Zhang Huimin Liao Xin Liu Pengfei Li Yali Feng Lei An Yongyong Zhuang Zhuo Xu Xiaoyong Wei | 2023 | Journal of Advanced Ceramics2023，12，7： | 0 |
| 18 | The critical factors of photocatalytic H2 production from seawater by using TiO_(2)as photocatalyst显示文摘The solar H_(2)generation directly from natural seawater is a sustainable way of green energy.However,it is limited by a low H_(2)generation rate even compared to fresh water.In this report,TiO_(2)is chosen as a model photocatalyst to disclose the critical factor to deteriorate the H_(2)generation rate from seawater.The simulated seawater(SSW),which is composed of eight ions(Na^(+),K^(+),Ca^(2+),Mg^(2+),Cl^(−),Br^(−),SO_(4)^(2−),and CO_(3)^(2−)),is investigated the effect of each ion on the H_(2)production.The results indicate that all ions have a negative effect at the same concentration as in the seawater except Br−.The CO_(3)^(2−)has the most serious deterioration,and the H_(2)production rate lowers near 40%even at[CO_(3)^(2−)]of 1.5 mmol·L^(−1).The H_(2)production rate can be recovered to 85%if the CO_(3)^(2−)is excluded from the SSW.To understand the reason,the zeta potential of the TiO_(2)treated with different ions aqueous solution reveals that the zeta potential decreases when it is treated with CO_(3)^(2−)and SO_(4)^(2−)due to they can adsorb on the surface of TiO_(2)nanoparticles.Fourier transform infrared(FTIR)and thermogravimetric analysis-mass spectroscopy(TGA-MS)further confirm that the adsorbed ion is mainly from CO_(3)^(2−).Since the pH of seawater is about 8.9 between pKa1(6.37)and pKa2(10.3)of H_(2)CO3,the CO_(3)^(2−)should exist in the form of HCO3−in the seawater.We proposed a simple method to remove the adsorbed HCO3−from the TiO_(2)surface by adjusting the pH below the pKa1.The results indicate that if a trace amount of HCl(adjusting pH~6.0)is added to the SSW,the H_(2)production rate can be recovered to 85%of that in pure water. | Yaqian He Pengfei Li Wenning Liu Li An Dan Qu Xiayan Wang Zaicheng Sun | 2023 | Nano Research2023，16，4： | 0 |
| 19 | Nickel phosphide for MRI-guided synergistic photo-immunotherapy显示文摘Developing a phototherapy modality to ablate tumor and then trigger immunogenic cell death(ICD)for simultaneously eliminating distal and metastatic tumors holds great promise in clinical applications.Herein,the polyethylene glycol functionalized Ni_(2)P(Ni_(2)P@PEG NPs)is developed with enhanced biocompatibility,high photoabsorption and photothermal efficiency,as well as reactive oxygen species generation ability.Of particular note,Ni_(2)P@PEG NPs mediated phototherapy could not only realize efficient ablation of primary tumors,but also inhibit distal tumors and metastatic tumors by triggering an antitumor immune response.The above conclusions were verified by B mode ultrasound,western blot assay,and immunohistochemistry analysis.Meanwhile,Ni_(2)P@PEG NPs showed excellent magnetic resonance imaging(MRI)properties.In summary,the MRI-guided multimodal cancer therapies of Ni_(2)P@PEG NPs represent significant potential for clinical applications. | Na An Yan Gao Ying Shi Xingxing Du Jianing Cheng Shuanglong Tang Pengfei Liu Huike Yang Chongshen Guo | 2023 | Journal of Materials Science & Technology2023，，20： | 0 |
| 20 | A novel multi-threshold coupling InAlN/GaN double-channel HEMT for improving transconductance flatness显示文摘GaN-based HEMTs have significant advantages,making them a prime choice for high-frequency,high-power switching [1].However,the inherent poor linearity of GaN HEMT has yet to be solved,which can be reflected by the nonlinearity of the transconductance (Gm) profile [2].This makes it hard to achieve high data transmission efficiency and less signal distortion in the wireless communication system [3]. | Sirui AN Minhan MI Pengfei WANG Sijia LIU Qing ZHU Meng ZHANG Zhihong CHEN Jielong LIU Siyin GUO Can GONG Xiaohua MA Yue HAO | 2024 | Science China(Information Sciences)2024，67，1： | 0 |
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