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| 1 | A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV) infected pneumonia(standard version)显示文摘In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province;and then named '2019 novel coronavirus(2019-nCoV)' by the World Health Organization(WHO) on 12 January 2020. For it is a never been experienced respiratory disease before and with infection ability widely and quickly, it attracted the world’s attention but without treatment and control manual. For the request from frontline clinicians and public health professionals of 2019-nCoV infected pneumonia management, an evidence-based guideline urgently needs to be developed. Therefore, we drafted this guideline according to the rapid advice guidelines methodology and general rules of WHO guideline development;we also added the first-hand management data of Zhongnan Hospital of Wuhan University. This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, treatment and control(including traditional Chinese Medicine), nosocomial infection prevention and control, and disease nursing of the 2019-nCoV. Moreover, we also provide a whole process of a successful treatment case of the severe 2019-nCoV infected pneumonia and experience and lessons of hospital rescue for 2019-nCoV infections. This rapid advice guideline is suitable for the first frontline doctors and nurses, managers of hospitals and healthcare sections, community residents, public health persons, relevant researchers, and all person who are interested in the 2019-nCoV. | Ying-Hui Jin Lin Cai Zhen-Shun Cheng Hong Cheng Tong Deng Yi-Pin Fan Cheng Fang Di Huang Lu-Qi Huang Qiao Huang Yong Han Bo Hu Fen Hu Bing-Hui Li Yi-Rong Li Ke Liang Li-Kai Lin Li-Sha Luo Jing Ma Lin-Lu Ma Zhi-Yong Peng Yun-Bao Pan Zhen-Yu Pan Xue-Qun Ren Hui-Min Sun Ying Wang Yun-Yun Wang Hong Weng Chao-Jie Wei Dong-Fang Wu Jian Xia Yong Xiong Hai-Bo Xu Xiao-Mei Yao Yu-Feng Yuan Tai-Sheng Ye Xiao-Chun Zhang Ying-Wen Zhang Yin-Gao Zhang Hua-Min Zhang Yan Zhao Ming-Juan Zhao Hao Zi Xian-Tao Zeng Yong-Yan Wang Xing-Huan Wang 无 | 2020 | Military Medical Research2020，7，1： | 161 |
| 2 | Latest Progress of the Chinese Meteorological Satellite Program and Core Data Processing Technologies显示文摘In this paper,the latest progress,major achievements and future plans of Chinese meteorological satellites and the core data processing techniques are discussed.First,the latest three FengYun(FY)meteorological satellites(FY-2H,FY-3D,and FY-4A)and their primary objectives are introduced Second,the core image navigation techniques and accuracies of the FY meteorological satellites are elaborated,including the latest geostationary(FY-2/4)and polar-orbit(FY-3)satellites.Third,the radiometric calibration techniques and accuracies of reflective solar bands,thermal infrared bands,and passive microwave bands for FY meteorological satellites are discussed.It also illustrates the latest progress of real-time calibration with the onboard calibration system and validation with different methods,including the vicarious China radiance calibration site calibration,pseudo invariant calibration site calibration,deep convective clouds calibration,and lunar calibration.Fourth,recent progress of meteorological satellite data assimilation applications and quantitative science produce are summarized at length.The main progress is in meteorological satellite data assimilation by using microwave and hyper-spectral infrared sensors in global and regional numerical weather prediction models.Lastly,the latest progress in radiative transfer,absorption and scattering calculations for satellite remote sensing is summarized,and some important research using a new radiative transfer model are illustrated. | Peng ZHANG Qifeng LU Xiuqing HU Songyan GU Lei YANG Min MIN Lin CHEN Na XU Ling Sun Wenguang BAI Gang MA Di XIAN | 2019 | Advances in Atmospheric Sciences2019，36，9： | 26 |
| 3 | Comparison of membrane fouling during short-term filtration of aerobic granular sludge and activated sludge显示文摘氧气的小粒的污泥被栽培采用定序批空运反应堆的内部传播。关于短期的膜在氧气的小粒的污泥系统和活性污泥系统之间犯规的对比的实验被调查。膜肮脏蚂蚁被 Fourier 变换也描绘红外线(FTIR ) 光谱学技术。结果证明氧气的小粒的污泥有优秀脱氮能力;TN 的移动效率能到达 90% 。氧气的小粒的污泥能减轻有效地犯规的膜。氧气的小粒的污泥的稳定的膜流动是两次像活性污泥系统的一样。另外,氧气的小粒的污泥能导致严重的膜,这被发现堵住毛孔然而,活性污泥能引起犯规的严重蛋糕。肮脏蚂蚁的主要部件作为蛋白质和多糖材料包括被识别。 | ZHOU Jun YANG Feng-lin MENG Fan-gang AN Peng WANG Di | 2007 | Journal of Environmental Sciences2007，19，11： | 18 |
| 4 | Stability of QTL Across Environments and QTL-by-Environment Interactions for Plant and Ear Height in Maize显示文摘Better understanding of genotype-by-environment interaction(GEI)is expected to provide a solid foundation for genetic improvement of crop productivity especially under drought-prone environments.To elucidate the genetic basis of the plant and ear height,2 F2:3 populations were derived from the crosses of Qi 319 × Huangzaosi(Q/H)and Ye 478 × Huangzaosi(Y/H)with 230 and 235 families,respectively,and their parents were evaluated under 3 diverse environments in Henan,Beijing,and Xinjiang,China during the year of 2007 and 2008,and all the lines were also evaluated under water stress environment.The mapping results showed that a total of 21 and 12 QTLs were identified for plant height in the Q/H and Y/H population,respectively,and 24 and 13 QTLs for ear height,respectively.About 56 and 73% of the QTLs for 2 traits did not present significant QTL-by-environment interaction(QEI)in the normal joint analyses for Q/H and Y/H population,respectively,and about 73% of the QTLs detected did not show significant QEI according to joint analyses for stress condition in Q/H.Most of the detected major QTLs exhibited high stability across different environments.Besides,several major QTLs were detected with large and consistent effect under normal condition(Chr.6 and 7 in Q/H;Chr.1,3 and 9 in Y/H),or across 2 water regimes(Chr.1,8 and 10 for in Q/H).There were several constitutive QTLs(3 for Q/H and 1 for Y/H)with no or minor QTL-by-environment for the 2 populations.Finally,we found several genomic regions(Chr.1,10,etc.)to be co-located across the populations,which could provide useful reference for genetic improvement of these traits in maize breeding programs.Comparative genomic analysis revealed that 3 genes/genetic segments associated with plant height in rice were orthologous to these 3 identified genomic regions carrying the major QTLs for plant and ear height on Chr.1,6,and 8,respectively. | ZHANG Yan LI Yong-xiang WANG Wang LIU Zhi-zhai LIU Cheng PENG Bo TAN Wei-wei WANG Di SHI Yun-su SUN Bao-cheng SONG Yan-chun WANG Tian-yu LI Yu | 2010 | Agricultural Sciences in China2010，9，10： | 16 |
| 5 | High precision landing site mapping and rover localization for Chang'e-3 mission显示文摘This paper presents the comprehensive results of landing site topographic mapping and rover localization in Chang’e-3 mission.High-precision topographic products of the landing site with extremely high resolutions(up to 0.05 m)were generated from descent images and registered to CE-2 DOM.Local DEM and DOM with 0.02 m resolution were produced routinely at each waypoint along the rover traverse.The lander location was determined to be(19.51256°W,44.11884°N,-2615.451 m)using a method of DOM matching.In order to reduce error accumulation caused by wheel slippage and IMU drift in dead reckoning,cross-site visual localization and DOM matching localization methods were developed to localize the rover at waypoints;the overall traveled distance from the lander is 114.8 m from cross-site visual localization and 111.2 m from DOM matching localization.The latter is of highest accuracy and has been verified using a LRO NAC image where the rover trajeactory is directly identifiable.During CE-3 mission operations,landing site mapping and rover localization products including DEMs and DOMs,traverse maps,vertical traverse profiles were generated timely to support teleoperation tasks such as obstacle avoidance and rover path planning. | LIU ZhaoQin DI KaiChang PENG Man WAN WenHui LIU Bin LI LiChun YU TianYi WANG BaoFeng ZHOU JianLiang CHEN HongMin | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，1： | 15 |
| 6 | Biofunctional magnesium coated Ti6Al4V scaffold enhances osteogenesis and angiogenesis in vitro and in vivo for orthopedic application显示文摘The insufficient osteogenesis and osseointegration of porous titanium based scaffold limit its further application.Early angiogenesis is important for scaffold survival.It is necessary to develop a multifunctional surface on titanium scaffold with both osteogenic and angiogenic properties.In this study,a biofunctional magnesium coating is deposited on porous Ti6Al4V scaffold.For osseointegration and osteogenesis analysis,in vitro studies reveal that magnesium-coated Ti6Al4V co-culture with MC3T3-E1 cells can improve cell proliferation,adhesion,extracellular matrix(ECM)mineralization and ALP activity compared with bare Ti6Al4V cocultivation.Additionally,MC3T3-E1 cells cultured with magnesium-coated Ti6Al4V show significantly higher osteogenesisrelated genes expression.In vivo studies including fluorochrome labeling,micro-computerized tomography and histological examination of magnesium-coated Ti6Al4V scaffold reveal that new bone regeneration is significantly increased in rabbits after implantation.For angiogenesis studies,magnesium-coated Ti6Al4V improve HUVECs proliferation,adhesion,tube formation,wound-healing and Transwell abilities.HUVECs cultured with magnesium-coated Ti6Al4V display significantly higher angiogenesis-related genes(HIF-1αand VEGF)expression.Microangiography analysis reveal that magnesium-coated Ti6Al4V scaffold can significantly enhance the blood vessel formation.This study enlarges the application scope of magnesium and provides an optional choice to the conventional porous Ti6Al4V scaffold with enhanced osteogenesis and angiogenesis for further orthopedic applications. | Peng Gao Bo Fan Xiaoming Yu Wenwen Liu Jie Wu Lei Shi Di Yang Lili Tan Peng Wan Yulin Hao Shujun Li Wentao Hou Ke Yang Xiaokang Li Zheng Guo | 2020 | Bioactive Materials2020，5，3： | 15 |
| 7 | Fengyun Meteorological Satellite Products for Earth System Science Applications显示文摘Following the progress of satellite data assimilation in the 1990s, the combination of meteorological satellites and numerical models has changed the way scientists understand the earth. With the evolution of numerical weather prediction models and earth system models, meteorological satellites will play a more important role in earth sciences in the future. As part of the space-based infrastructure, the Fengyun (FY) meteorological satellites have contributed to earth science sustainability studies through an open data policy and stable data quality since the first launch of the FY-1A satellite in 1988. The capability of earth system monitoring was greatly enhanced after the second-generation polar orbiting FY-3 satellites and geostationary orbiting FY-4 satellites were developed. Meanwhile, the quality of the products generated from the FY-3 and FY-4 satellites is comparable to the well-known MODIS products. FY satellite data has been utilized broadly in weather forecasting, climate and climate change investigations, environmental disaster monitoring, etc. This article reviews the instruments mounted on the FY satellites. Sensor-dependent level 1 products (radiance data) and inversion algorithm-dependent level 2 products (geophysical parameters) are introduced. As an example, some typical geophysical parameters, such as wildfires, lightning, vegetation indices, aerosol products, soil moisture, and precipitation estimation have been demonstrated and validated by in-situ observations and other well-known satellite products. To help users access the FY products, a set of data sharing systems has been developed and operated. The newly developed data sharing system based on cloud technology has been illustrated to improve the efficiency of data delivery. | Di XIAN Peng ZHANG Ling GAO Ruijing SUN Haizhen ZHANG Xu JIA | 2021 | Advances in Atmospheric Sciences2021，38，8： | 14 |
| 8 | Serum Uric Acid is Associated with the Predicted Risk of Prevalent Cardiovascular Disease in a Community-dwelling Population without Diabetes显示文摘Objective To examine the association between serum uric acid levels and cardiovascular disease risk among individuals without diabetes. Methods We investigated the association between serum uric acid levels and the risk of prevalent cardiometabolic diseases, 10-year Framingham risk for coronary heart disease, and 10-year risk for atherosclerotic cardiovascular diseases(ASCVD) among 8,252 participants aged ≥ 40 years without diabetes from Jiading district, Shanghai, China. Results Body mass index, waist circumference, blood glucose, glycated hemoglobin, blood pressure, and serum lipids increased progressively across the sex-specific quartiles of uric acid(all P trend < 0.05). Compared with individuals in the lowest quartile, those in the higher quartiles had a significantly higher prevalence of obesity, hypertension, and dyslipidemia(all P trend < 0.05). A fully adjusted logistic regression analysis revealed that individuals in the highest quartile had an increased risk of predicted cardiovascular disease compared with those in the lowest quartile of uric acid. The multivariate adjusted odds ratios(ORs) [95% confidence intervals(CIs)] for the highest quartiles for high Framingham risk were 3.00(2.00-4.50) in men and 2.95(1.08-8.43) in women. The multivariate adjusted ORs(95% CIs) for the highest quartile for high ASCVD risk were 1.93(1.17-3.17) in men and 4.53(2.57-7.98) in women. Conclusion Serum uric acid level is associated with an increased risk of prevalent obesity, hypertension, dyslipidemia, 10-year Framingham risk for coronary heart disease, and 10-year risk for ASCVD among Chinese adults without diabetes. | CHENG Di DU Rui WU Xue Yan LIN Lin PENG Kui MA Li Na XU Yu XU Min CHEN Yu Hong BI Yu Fang WANG Wei Qing DAI Meng LU Jie Li | 2018 | Biomedical and Environmental Sciences2018，31，2： | 13 |
| 9 | Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication显示文摘Hepatitis B virus(HBV)can cause chronic hepatitis B,which may lead to cirrhosis and liver cancer.Type I interferon(IFN)is an approved drug for the treatment of chronic hepatitis B.However,the fundamental mechanisms of antiviral action by type I IFN and the downstream signaling pathway are unclear.TRIM25 is an IFN-stimulated gene(ISG)that has an important role in RIG-I ubiquitination and activation.Whether TRIM25 is induced in liver cells by type I IFN to mediate anti-HBV function remains unclear.Here we report that interleukin-27(IL-27)has a critical role in IFN-induced TRIM25 upregulation.TRIM25 induction requires both STAT1 and STAT3.In TRIM25 knockout HepG2 cells,type I IFN production was consistently attenuated and HBV replication was increased,whereas overexpression of TRIM25 in HepG2 cells resulted in elevated IFN production and reduced HBV replication.More interestingly,we found that TRIM25 expression was downregulated in HBV patients and the addition of serum samples from HBV patients could inhibit TRIM25 expression in HepG2 cells,suggesting that HBV might have involved a mechanism to inhibit antiviral ISG expression and induce IFN resistance.Collectively,our results demonstrate that type I IFN-induced TRIM25 is an important factor in inhibiting HBV replication,and the IFN-IL-27-TRIM25 axis may represent a new target for treating HBV infection. | Guangyun Tan Qingfei Xiao Hongxiao Song Feng Ma Fengchao Xu Di Peng Na Li Xiaosong Wang Junqi Niu Pujun Gao F Xiao-Feng Qin Genhong Cheng | 2018 | Cellular & Molecular Immunology2018，15，3： | 13 |
| 10 | MiRNA-429 suppresses the growth of gastric cancer cells in vitro显示文摘Micro-RNAs(miRNAs) have been found to be implicated in a very wide range of physiological processes.This study was aimed to investigate the regulation of miRNA-429(miR-429) in gastric cancer cells on cell proliferation and apoptosis.Quantitative PCR was employed to detect the expressions of miR-429 after eukaryotic expression plasmid of miR-429 and its inhibitor were transiently transfected into poorly differentiated human gastric can-cer cell line BGC823.The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) reduction as-says were used to examine proliferation ability.Apoptosis was analyzed by flow cytometry after transfection.The results showed that 48 h after transfection,overexpression of miR-429 reached maximum efficiency.Compared with mock transfection,miR-429 inhibited tumor cell proliferation significantly(P < 0.05) at 48 h and 72 h.of Overexpression of miR-429 promoted tumor cell apoptosis when compared with mock transfected cells(P < 0.05).On the contrary,miR-429 inhibitor promoted tumor cell proliferation and inhibited apoptosis when compared with controls(P < 0.05).Our results suggested that miRNA-429 may serve as a tumor suppressor during tumorigenesis of gastric cancer and may be a potential gastric cancer therapeutic target. | Di Liu Peng Xia Dongmei Diao Yao Cheng Hao Zhang Dawei Yuan Chen Huang Chengxue Dang | 2012 | The Journal of Biomedical Research2012，26，5： | 12 |
| 11 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 12 | Commissioning progress of the FAST显示文摘The Five-hundred-meter Aperture Spherical radio Telescope(FAST) was completed with its main structure installed on September 25, 2016, after which it entered the commissioning phase. This paper aims to introduce the commissioning progress of the FAST over the past two years. To improve its operational reliability and ensure effective observation time, FAST has been equipped with a real-time information system for the active reflector system and hierarchical commissioning scheme for the feed support system, which ultimately achieves safe operation of the two systems. For meeting the high-performance indices, a highprecision measurement system was set up based on the effective control methods that were implemented for the active reflector system and feed support system. Since the commissioning of the FAST, a low-frequency ultra-wideband receiver and 19-beam1.05-1.45 GHz receiver have been mainly used. Telescope efficiency, pointing accuracy, and system noise temperature were completely tested and ultimately achieved the acceptance indices of the telescope. The FAST has been in the process of national acceptance preparations and has begun to search for pulsars. In the future, it will still strive to improve its capabilities and expand its application prospects. | Peng Jiang YouLing Yue HengQian Gan Rui Yao Hui Li GaoFeng Pan JingHai Sun DongJun Yu HongFei Liu NingYu Tang Lei Qian JiGuang Lu Jun Yan Bo Peng ShuXin Zhang QiMing Wang Qi Li Di Li | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，5： | 11 |
| 13 | Recent Progress of Fengyun Meteorology Satellites显示文摘After nearly 50 years of development, Fengyun(FY) satellite ushered in its best moment. China has become one of the three countries or units in the world(China, USA, and EU) that maintain both polar orbit and geostationary orbit satellites operationally. Up to now, there are 17 Fengyun(FY) satellites that have been launched successfully since 1988. There are two FY polar orbital satellites and four FY geostationary orbit satellites operate in the space to provide a huge amount of the earth observation data to the user communities. The FY satellite data has been applied not only in the meteorological but also in agriculture,hydraulic engineering, environmental, education, scientific research and other fields. More recently, three meteorological satellites have been launched within the past two years. They are FY-4 A on 11 December2016, FY-3 D on 15 November 2017 and FY-2 H on 5 June 2018. This paper introduces the current status of FY meteorological satellites and data service. The updates of the latest three satellites have been addressed.The characteristics of their payloads on-boarding have been specified in details and the benefit fields have been anticipated separately. | ZHANG Peng CHEN Lin XIAN Di XU Zhe | 2018 | 空间科学学报2018，38，5： | 11 |
| 14 | Association between well-characterized lung cancer IncRNA polymorphisms and platinum-based chemotherapy toxicity in Chinese patients with lung cancer显示文摘基于铂的化疗是为大多数肺癌症病人的标准首要的治疗。然而,基于铂的化疗极大地导致的毒性阻碍它的临床的使用。以前的研究证明有在长度的超过 200 核苷酸的长非编码的 RNA (lncRNAs ) 影响药反应和毒性。在现在的学习,我们与肺癌症在中国病人与基于铂的化疗毒性调查了描绘得好的肺癌症 lncRNA 多型性的协会。467 个肺癌症病人的一个总数与基于铂的化疗对待因为至少二个周期被招募。我们首先集中了于胃肠并且 hematological 毒性。在 8 lncRNAs (HOTTIP, HOTAIT, H19, ANRIL, CCAT2, MALAT1, MEG3,和 POLR2E ) 以内的 14 潜在地功能的多型性的一个总数是 genotyped。无条件的后勤的回归分析被进行估计协会。基因基因和基因环境相互作用用软件被识别概括 multifactor 维数减小(GMDR ) 。ANRIL rs1333049 在一个添加剂模型与严重全面毒性被联系(调整 OR=0.723, 95% CI=0.541-0.965, P=0.028 ) 。ANRIL rs1333049 也在两个与严重胃肠的毒性被联系添加剂(调整 OR=0.690, 95% CI=0.489-0.974, P=0.035 ) 并且主导(调整 OR=0.558, 95% CI=0.335-0.931, P=0.025 ) 模型。MEG3 rs116907618 在一个添加剂模型与严重胃肠的毒性被联系(调整 OR=1.717, 95% CI=1.007-2.927, P=0.047 ) 。GMDR 为 hematological 毒性作为最好的预兆的模型识别了 POLR2E rs3787016-HOTTIP rs3807598 化疗政体的三因素的相互作用模型。在结论, ANRIL 和 MEG3,基因多型性与严重的铂毒性被联系并且能与肺癌症在中国病人为预告的处理评估被看作 biomarkers。 | Wei-jing GONG Jing-bo PENG Ji-ye YIN Xiang-ping LI Wei ZHENG Ling XIAO Li-ming TAN Di XIAO Yi-xin CHEN Xi LI Hong-hao ZHOU Zhao-qian LIU | 2017 | Acta Pharmacologica Sinica2017，38，4： | 10 |
| 15 | Subtle trap recognition based on seismic sedimentology- A case study from Shengli Oilfield显示文摘地震沉积科学用地震数据是沉积岩石和外形的学习。然而,经常,沉积身体特征不能被描述份量上由于地震分辨率的限制。高决定倒置抵消这限制并且被用于地震沉积科学在复杂地质的条件下面识别微妙的陷井,从而拓宽地震沉积科学的适用的范围。在这篇论文,基于地震沉积科学,地震控制阶段的非线性的随机的倒置被用来在 Shengli 油矿在 Chezhen 消沉预言 Es3 的沙的集团企业水库。厚度和在几个阶段的沙的集团企业身体的沉积微外形地图被钻介绍,几个微妙的陷井被预言并且验证。 | Huang Handong Zhang Ruwei Luo Qun Zhao Di Peng Yongmin | 2009 | Applied Geophysics2009，6，2： | 10 |
| 16 | Influence of Chromium on Corrosion Behavior of Low-alloy Steel in Cargo Oil Tank O_2-CO_2-SO_2-H_2S Wet Gas Environment显示文摘As international maritime organization(IMO)draft 289 was adopted to develop a low-alloy anti-corrosion steel for the deck of cargo oil tank and to understand corrosion mechanism,corrosion behavior of a low-alloy steel with chromium contents was studied in O2-CO2-SO2-H2 S wet gas environment.Corrosion rate was measured,and the microstructure and morphology of corrosion product film were characterized by scanning electron microscopy(SEM).The phase and chemical composition of the corrosion product film were investigated by X-ray diffraction(XRD)and energy dispersive spectroscopy(EDS),respectively.The effect of misorientation distribution on corrosion resistance of steel was evaluated by electron backscattered diffraction(EBSD).The results showed that corrosion rate decreased with increasing chromium content in the low-alloy steel,and the corrosion type was general corrosion.The phenomenon of chromium enrichment was found in corrosion product film consisting ofα-FeOOH,γ-FeOOH,sulphur,FeS2 and Fe1-xS.The increase of chromium content decreases the amount of high-angle grain boundaries,thus resulting in the improvement of corrosion resistance. | Peng ZHOU Jin-ming LIANG Fei ZHANG Hui-bin WU Di TANG | 2015 | Journal of Iron and Steel Research(International)2015，22，7： | 9 |
| 17 | Hard X-ray Imager (HXI) onboard the ASO-S mission显示文摘Hard X-ray Imager(HXI)is one of the three scientific instruments onboard the Advanced Spacebased Solar Observatory(ASO-S)mission,which is proposed for the 25th solar maximum by the Chinese solar community.HXI is designed to investigate the non-thermal high-energy electrons accelerated in solar flares by providing images of solar flaring regions in the energy range from 30 keV to 200 keV.The imaging principle of HXI is based on spatially modulated Fourier synthesis and utilizes about 91 sets of bi-grid sub-collimators and corresponding LaBr3 detectors to obtain Fourier components with a spatial resolution of about 3 arcsec and a time resolution better than 0.5 s.An engineering prototype has been developed and tested to verify the feasibility of design.In this paper,we present background,instrument design and the development and test status of the prototype. | Zhe Zhang Deng-Yi Chen Jian Wu Jin Chang Yi-Ming Hu Yang Su Yan Zhang Jian-Ping Wang Yao-Ming Liang Tao Ma Jian-Hua Guo Ming-Sheng Cai Yong-Qiang Zhang Yong-Yi Huang Xiao-Yan Peng Zong-Bin Tang Xuan Zhao Hong-He Zhou Lian-Guo Wang Jing-Xing Song Miao Ma Guang-Zhou Xu Jian-Feng Yang Di Lu Ying-Hong He Jin-You Tao Xiao-Long Ma Bao-Gang Lv Yan-Ping Bai Cai-Xia Cao Yu Huang Wei-Qun Gan | 2019 | Research in Astronomy and Astrophysics2019，19，11： | 9 |
| 18 | Design of a spatial sampling scheme considering the spatial autocorrelation of crop acreage included in the sampling units显示文摘Information on crop acreage is important for formulating national food polices and economic planning.Spatial sampling,a combination of traditional sampling methods and remote sensing and geographic information system(GIS)technology,provides an efficient way to estimate crop acreage at the regional scale.Traditional sampling methods require that the sampling units should be independent of each other,but in practice there is often spatial autocorrelation among crop acreage contained in the sampling units.In this study,using Dehui County in Jilin Province,China,as the study area,we used a thematic crop map derived from Systeme Probatoire d’Observation de la Terre(SPOT-5)imagery,cultivated land plots and digital elevation model data to explore the spatial autocorrelation characteristics among maize and rice acreage included in sampling units of different sizes,and analyzed the effects of different stratification criteria on the level of spatial autocorrelation of the two crop acreages within the sampling units.Moran’s I,a global spatial autocorrelation index,was used to evaluate the spatial autocorrelation among the two crop acreages in this study.The results showed that although the spatial autocorrelation level among maize and rice acreages within the sampling units generally decreased with increasing sampling unit size,there was still a significant spatial autocorrelation among the two crop acreages included in the sampling units(Moran’s I varied from 0.49 to 0.89),irrespective of the sampling unit size.When the sampling unit size was less than3 000 m,the stratification design that used crop planting intensity(CPI)as the stratification criterion,with a stratum number of 5 and a stratum interval of 20%decreased the spatial autocorrelation level to almost zero for the maize and rice area included in sampling units within each stratum.Therefore,the traditional sampling methods can be used to estimate the two crop acreages.Compared with CPI,there was still a strong spatial correlation among the two crop acreages included in the sampling units belonging to each stratum when cultivated land fragmentation and ground slope were used as stratification criterion.As far as the selection of stratification criteria and sampling unit size is concerned,this study provides a basis for formulating a reasonable spatial sampling scheme to estimate crop acreage. | WANG Di ZHOU Qing-bo YANG Peng CHEN Zhong-xin | 2018 | Journal of Integrative Agriculture2018，17，9： | 9 |
| 19 | Analysis of reference gene expression for real-time PCR based on relative quantitation and dual spike-in strategy in the silkworm Bombyx mori显示文摘为即时量的聚合酶链反应(qPCR ) ,一般来说,正规化策略把引用基因用作控制并且不应该响应改变条件变化避免这基因的试验性的错误表示的介绍。然而,许多参考基因的表示被报导了更加变化,没有适当正规化,目标基因的表示侧面能被曲解。在这研究,七的表达式层次通常使用了引用基因(行为, GAPDH, 28srRNA, RPL3, -tubulin, UBC,和 TBP ) 与 20-hydroxyecdysone (20E ) 并且与卢丁在不同开发时间点并且响应处理被检测。表示稳定性用 geNorm 和 NormFinder 软件被分析。重要变化在正常纸巾之中并且在试验性地对待的纸巾之间被发现。双刺在里面策略也在正常纸巾之中并且在试验性地对待的纸巾之间揭示了参考基因的表示层次的重要变化。Glutathione-S-transferase 西格马 1 (GSTs1 ) ,它在胖身体有高表达式水平并且与抵抗的机制有关,被用作目标基因验证这二条途径的可行性和差别。 | Ran Peng Yuanfen Zhai Hua Ding Tianyuan Di Ting Zhang Bing Li Weide Shen Zhengguo Wei | 2012 | Acta Biochimica et Biophysica Sinica2012，44，7： | 8 |
| 20 | Ultrafine particle emission characteristics of diesel engine by on-board and test bench measurement显示文摘This study investigated the emission characteristics of ultrafine particles based on test bench and on-board measurements. The bench test results showed the ultrafine particle number concentration of the diesel engine to be in the range of (0.56-8.35)×10 8cm-3. The on-board measurement results illustrated that the ultrafine particles were strongly correlated with changes in real-world driving cycles. The particle number concentration was down to 2.0×106cm-3 and 2.7×107cm-3 under decelerating and idling operations and as high as 5.0×108cm-3 under accelerating operation. It was also indicated that the particle number measured by the two methods increased with the growth of engine load at each engine speed in both cases. The particle number presented a 'U' shaped distribution with changing speed at high engine load conditions, which implies that the particle number will reach its lowest level at medium engine speeds. The particle sizes of both measurements showed single mode distributions. The peak of particle size was located at about 50-80nm in the accumulation mode particle range. Nucleation mode particles will significantly increase at low engine load operations like idling and decelerating caused by the high concentration of unburned organic compounds. | Cheng Huang Diming Lou Zhiyuan Hu Piqiang Tai Di Yao Wei Hu Peng Li Jin Ren Changhong Chen | 2012 | Journal of Environmental Sciences2012，24，11： | 8 |
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