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| 1 | Microscopic colitis:A large retrospective analysis from a health maintenance organization experience显示文摘AIM:To examine the demographic data on a large multi-ethnic population of patients with microscopic colitis (MC) in Southern California and to determine the association of MC with inflammatory bowel disease (IBD) and colorectal cancer.METHODS: All patients diagnosed with MC by colonic biopsy from 1996-2005 were identified utilizing a pathology database. All biopsies were reviewed by experienced pathologists utilizing standard histologic criteria. Patients' medical records were reviewed and data regarding patient age, co-morbidities, sex, ethnicity, and medications were analyzed. An age-and sexmatched standard control group was also generated. Chi-square test was used to evaluate the associations of co-morbidities between lymphocytic colitis (LC), collagenous colitis (CC) and the control group.RESULTS: A total of 547 cases of MC were identif ied,376 patients with LC and 171 patients with CC. The female/male ratio was 3:1 in CC and 2.7:1 in LC patients. Celiac disease (P<0.001), irritable bowel syndrome (IBS) (P<0.001), and thyroid diseases (P<0.001) were found to have a higher occurrence in MC compared to the control group. No statistical differences in the occurrence of colorectal cancer, diabetes and IBD were found between the MC group and the control group.CONCLUSION: This is the largest group of patients with MC known to the authors that has been studied to date. Conditions such as celiac disease, IBS, and thyroid diseases were found to be related to MC. Furthermore, neither an increased risk of colorectal cancer nor IBD was associated with MC in this study. | Kevin T Kao Benito A Pedraza Amy C McClune David A Rios Yi-Qiong Mao Robert H Zuch Michael H Kanter Sony Wirio Chris N Conteas | 2009 | World Journal of Gastroenterology2009，15，25： | 5 |
| 2 | Modern data sources and techniques for analysis and forecast of road accidents:A review显示文摘Road accidents are one of the most relevant causes of injuries and death worldwide,and therefore,they constitute a significant field of research on the use of advanced algorithms and techniques to analyze and predict traffic accidents and determine the most relevant elements that contribute to road accidents.The research of road accident prediction aims to respond to the challenge of offer tools to generate a more secure mobility environment,and ultimately,save lives.This paper aims to provide an overview of the state of the art in the prediction of road accidents through machine learning algorithms and advanced techniques for analyzing information,such as convolutional neural networks and long short-term memory networks,among other deep learning architectures.Furthermore,in this article,a compendium and study of the most used data sources for the road accident forecast is made.And a classification is proposed according to its origin and characteristics,such as open data,measurement technologies,onboard equipment and social media data.For the analysis of the information,the different algorithms employed to make predictions about road accidents are listed and compared,as well as their applicability depending on the types of data being analyzed,along with the results obtained and their ease of interpretation and analysis.The best results reported by the authors are obtained when two or more analytic techniques are combined,in such a way that analysis of the obtained results is strengthened.Among the future challenges in road traffic forecasting lies the enhancement of the scope of the proposed models and predictions by the incorporation of heterogeneous data sources,that include geo spatial data,information from traffic volume,traffic statistics,video,sound,text and sentiment from social media,that many authors concur that can improve the precision and accuracy of the analysis and predictions. | Camilo Gutierrez-Osorio Cesar Pedraza | 2020 | Journal of Traffic and Transportation Engineering(English Edition)2020，7，4： | 3 |
| 3 | T cell immune responses to SARS-CoV-2 and variants of concern(Alpha and Delta)in infected and vaccinated individuals显示文摘Our understanding of immune responses to SARS-CoV-2 and variants of concern(VOCs)has been primarily acquired through analysis of Spike-specific IgG responses.However,a more comprehensive understanding of the breadth and longevity of immune responses after infection and vaccination requires analysis of cellular immunity.Herein,we report on T cell immunity in infected and vaccinated individuals,identifying CD4+/CD8+T cell cytokine responses to SARS-CoV-2 and variant peptides(Alpha,B.1.1.7 and Delta,B.1.617.2). | Stanley C.Jordan Bong-Ha Shin Terry-Ann M.Gadsden Maggie Chu Anna Petrosyan Catherine N.Le Rachel Zabner Jillian Oft Isabel Pedraza Susan Cheng Ashley Vo Noriko Ammerman Jasmine Plummer Shili Ge Max Froch Anders Berg Mieko Toyoda Ruan Zhang | 2021 | Cellular & Molecular Immunology2021，18，11： | 3 |
| 4 | Opportunities for treatment of the hepatitis C virus-infected patient with chronic kidney disease显示文摘The prevalence of hepatitis C virus(HCV) infection amongst patients with chronic kidney disease(CKD) and end-stage renal disease exceeds that of the general population. In addition to predisposing to the development of cirrhosis and hepatocellular carcinoma, infection with HCV has been associated with extra-hepatic complications including CKD, proteinuria, glomerulonephritis, cryoglobulinemia, increased cardiovascular risk, insulin resistance, and lymphoma. With these associated morbidities, infection with HCV is not unexpectedly accompanied by an increase in mortality in the general population as well as in patients with kidney disease. Advances in the understanding of the HCV genome have resulted in the development of direct-acting antiviral agents that can achieve much higher sustained virologic response rates than previous interferon-based protocols. The direct acting antivirals have either primarily hepatic or renal metabolism and excretion pathways. This information is particularly relevant when considering treatment in patients with reduced kidney function. In this context, some of these agents are not recommended for use in patients with a glomerular filtration rate < 30 m L/min per 1.73 m^2. There are now Food and Drug Administration approved direct acting antiviral agents for the treatment of patients with kidney disease and reduced function. These agents have been demonstrated to be effective with sustained viral response rates comparable to the general population with good safety profiles. A disease that was only recently considered to be very challenging to treat in patients with kidney dysfunction is now curable with these medications. | Marco Ladino Fernando Pedraza David Roth | 2017 | World Journal of Hepatology2017，9，19： | 2 |
| 5 | Vertebral artery embolism after acute cervical spine trauma显示文摘 | VERAS L M PEDRAZA GUTIERREZ S CASTELLANOS J el al | 2000 | Spine2000，25，9： | 1 |
| 6 | Vasovagal syncope:management with propantheline bromide显示文摘 | Corbala F Pacheco UA Pedraza IS | 1997 | Arch Inst Cardiol Mex1997，67，： | 1 |
| 7 | Akt regulates growth by directly phosphorylating Tsc2 显示文摘 | Potter C J Pedraza LG Xu T | 2002 | Nat Cell Biol2002，4，9： | 1 |
| 8 | Early stages of pulsed-laser growth of silicon microcolumns and microcones in air and SF6 显示文摘 | Lowndes D t-I Fowlkes J D Pedraza A 1 | 2000 | Applied Surface Science2000，15，4： | 1 |
| 9 | Study on the Al/silicon rich oxide/Si structure as a surge suppressor, DC,frequency responcy response and modeling 显示文摘 | Aceves M Pedraza J Reynoso-Hermandez A | 1999 | Microelectron J1999，30，： | 1 |
| 10 | Laparoscopic and robotic colorectal surgery: a comparison and contrast显示文摘 | Haas EM Pedraza R | 2013 | Semin Colon Rectal Surg2013，24，1： | 1 |
| 11 | The International Atomic Energy Agency (IAEA) Programme in Radiation and Tissue Banking: Past, Present and Future显示文摘 | Glyn O. Phillips Jorge M. Pedraza | 2003 | Cell and Tissue Banking2003，，： | 1 |
| 12 | Wallerian degeneration in the corticospinal tract evaluated by diffusion tensor imaging correlates with motor deficit 30 days after middle cerebral 'artery ischemie stroke显示文摘 | Josep P Pedraza S Blasco G et 'al | 2010 | AJNR2010，31，： | 1 |
| 13 | Akt regulates growth by directly phosphorylating Tsc2显示文摘 | POTTER C J PEDRAZA L G XU T | 2002 | Nature Cell Biology2002，4，9： | 1 |
| 14 | Building Long-Term Care Policies in Latin America: New Programs in Chile显示文摘 | Mauricio Matus-Lopez Camilo Cid Pedraza | 2015 | Journal of the American Medical Directors Associa2015，，： | 1 |
| 15 | The clinical-DWI mismatch:a new diagnostic approach to the brain tissue at risk of infarction显示文摘 | Davalos A Blanco M Pedraza S | 2004 | Neurology2004，62，12： | 1 |
| 16 | Thyroid hormones directly activate the expression of the human and mouse uncoupling protein-3 genes through a thyroid response element in the proximal promoter region显示文摘 | SOLANES G PEDRAZA N CALVO V | 2005 | Biochem J2005，386，3： | 1 |
| 17 | Nitridation effects on the oxidation mechanisms of an ods Fe-Al intermetallic alloy 显示文摘 | PEDRAZA F GROSSEAU-POUSSARD J L DINHUT J F | 2004 | Applied Surface Science2004，233，： | 1 |
| 18 | Midkine as a novel target gene for the Wilms' tumor suppressor gene ( WT1 ) 显示文摘 | Adachi Y Matsubara S Pedraza C | 1996 | Oncogene1996，13，10： | 1 |
| 19 | C-reactive protein used as an early indicator of infection in patients with systemic inflammatory response syndrome显示文摘 | Rafael Sierra Jordi Rello María Angeles Bailén Encarnación Benítez Antonio Gordillo Cristobal León Sebastián Pedraza | 2004 | Intensive Care Medicine2004，，11： | 1 |
| 20 | Osteopontin and wound healing in bone显示文摘 | MCKEE M D PEDRAZA C E KAARTINEN M T | 2011 | Cells Tissues Organs2011，194，24： | 1 |
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