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| 1 | 儿童观看卡通片激活内侧前额皮层显示文摘成人的内侧前额叶皮层(medial prefrontal cortex,MPFC)参与加工真实人物而非虚拟人造角色的心理活动.与成人相比,儿童更加迷恋卡通形象,本文研究儿童的MPFC活动是否也能区分加工真实人物和虚拟人造角色的心理活动.通过功能磁共振成像(functional magnetic resonance imaging,fMRI)测量10岁儿童观看电影和卡通片段时候的大脑激活情况,其中电影和卡通分别代表真实和虚拟生活场景.结果发现,与成人不同,儿童的MPFC在观看描述类似事件的真实人物和虚拟角色的时候都会被激活.这些结果表明,10岁左右的儿童观看虚拟现实中的人造角色时,其MPFC可以被自动激活,这与成人的MPFC活动不同. | 韩世辉 蒋毅 许晓婧 Glyn W.Humphreys | 2007 | 科学通报2007,52,19: | 10 |
| 2 | 共轭亚油酸水包油型乳液的物理化学稳定性显示文摘共轭亚油酸(conjugated linoleic acid,CLA)是一种具有多重生理功效的不饱和脂肪酸,其氧化稳定性较差,对光、热、氧气很不稳定。以亲水胶体为乳化剂制备CLA的水包油(O/W)型乳液可改善其氧化稳定性,扩大其在食品中的应用。该研究采用改性阿拉伯胶EM2为乳化剂、2种不同黏度的CLA为油相,通过测定乳液颗粒的粒径和粒径分布以及乳液在40℃贮存过程中的过氧化值和茴香胺值,研究了CLA的水包油(O/W)型乳液的物理化学稳定性。结果表明,高质量分数的EM2有利于形成粒径更小且分布均一的乳液颗粒。乳液的氧化稳定性很大程度上依赖于其物理稳定性。对于黏度较小的CLA,在各测试EM2质量分数下,CLA乳液具有较好的物理稳定性,且随着EM2质量分数的增大,乳液氧化稳定性提高。对于黏度较大的CLA,EM2质量分数为5%时,乳液具有较好的物理化学稳定性;增大EM2的质量分数,其稳定性下降。该研究可为今后研究基于乳液技术的功能性因子保护和增效提供参考,有利于CLA在食品行业中的推广应用。 | 徐琼 姚晓琳 王娜娜 田大志 方亚鹏 Glyn O.Phillips Katsuyoshi Nishinari | 2013 | 农业工程学报2013,29,11: | 10 |
| 3 | Lymph node metastases of adenocarcinoma of the esophagus and esophagogastric junction显示文摘背景食道的腺癌正在成为日益重要的 problem.It 大多数很快在最后十年在西方的国家一直在增加恶意,并且它的预后是这研究的 poor.The 目的是为食管和 esophagogastric 连接的腺癌评估在肿瘤侵略深度和淋巴节点转移之间的关系,并且学习组与 aden 包括了 121 个病人在 patients.Methods | ZHANG Xun David I Watson Glyn G Jamieson | 2007 | Chinese Medical Journal2007,,24: | 7 |
| 4 | 钙离子诱导的海藻酸钠/黄原胶凝胶化临界行为研究显示文摘研究了海藻酸钠/黄原胶混合体系的相行为及其对海藻酸钠-钙离子凝胶化临界行为的影响.当海藻酸钠浓度为0.5 wt%时,随着黄原胶的添加,混合体系出现相容、相分离及液晶3种不同的相行为.与纯黄原胶溶液相比,海藻酸钠/黄原胶混合溶液在更低的黄原胶浓度下开始形成液晶,这是由于混合体系中相分离的发生导致了黄原胶有效浓度升高.利用葡萄糖酸内酯(GDL)在线酸化Ca-EDTA,释放钙离子,研究了不同钙离子引入量时(f=[Ca2+]/[COO-])混合体系的黏弹性.Winter-Chambon分析发现临界凝胶点(f gel)随黄原胶浓度的增加而降低.当相分离发生时,临界凝胶点急剧降低,当液晶结构形成后,临界凝胶点呈现上升趋势.通过对比Winter-Chambon方法和临界凝胶点模量松弛法所测得的松弛临界指数(nw和nr),发现黄原胶的添加使海藻酸钠临界凝胶失去结构自相似性.相分离的发生导致临界凝胶结构排列更加致密,而液晶的出现使临界凝胶结构排列相对疏松. | 张帆 毛鹏 孔慧玲 赵萌 方亚鹏 Katsuyoshi Nishinari Glyn O.Phillips | 2013 | 高分子学报2013,23,11: | 7 |
| 5 | Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis显示文摘Lung injury and fibrosis represent the most significant outcomes of severe and acute lung disorders,including COVID-19.However,there are still no effective drugs to treat lung injury and fibrosis.In this study,we report the generation of clinical-grade human embryonic stem cells(hESCs)-derived immunity-and matrix-regulatory cells(IMRCs)produced under good manufacturing practice requirements,that can treat lung injury and fibrosis in vivo.We generate IMRCs by sequentially differentiating hESCs with serum-free reagents.IMRCs possess a unique gene expression profile distinct from that of umbilical cord mesenchymal stem cells(UCMSCs),such as higher expression levels of proliferative,immunomodulatory and anti-fibrotic genes.Moreover,intravenous delivery of IMRCs inhibits both pulmonary inflammation and fibrosis in mouse models of lung injury,and significantly improves the survival rate of the recipient mice in a dose-dependent manner,likely through paracrine regulatory mechanisms.IMRCs are superior to both primary UCMSCs and the FDA-approved drug pirfenidone,with an excellent efficacy and safety profile in mice and monkeys.In light of public health crises involving pneumonia,acute lung injury and acute respiratory distress syndrome,our findings suggest that IMRCs are ready for clinical trials on lung disorders. | Jun Wu Dingyun Song Zhongwen Li Baojie Guo Yani Xiao Wenjing Liu Lingmin Liang Chunjing Feng Tingting Gao Yanxia Chen Ying Li Zai Wang Jianyan Wen Shengnan Yang Peipei Liu Lei Wang Yukai Wang Liang Peng Glyn Nigel Stacey Zheng Hu Guihai Feng Wei Li Yan Huo Ronghua Jin Ng Shyh-Chang Qi Zhou Liu Wang Baoyang Hu Huaping Dai Jie Hao | 2020 | Cell Research2020,30,9: | 7 |
| 6 | 甲醛固定石蜡包埋组织中DNA的降解情况显示文摘 | 田子强 刘俊峰 王贵英 Eric Smith Paul Drew David Watson Glyn G Jamieson | 2004 | 中华病理学杂志2004,33,3: | 4 |
| 7 | 以最低成本生产符合国际标准的混凝土配筋用棒线材和棒材盘卷显示文摘最近几年,混凝土配筋用棒材的生产成本有所提高。造成成本增加的因素很多,其中包括能源成本和人工成本,但最主要的因素则是合金和微合金,比如钒的成本占有较大比重。在钢中加入合金元素钒,通常用于满足钢材力学性能要求。世界上越来越多的目前仍采用微合金化方法提高混凝土配筋力学性能的钢材生产商,正在寻求一种可以减少、甚至不用微合金元素的替代方法,以降低生产成本。分析了美国和国际最新标准提出的要求,并详细讨论了用于降低生产成本的新工艺、新技术的优点和限制条件。 | Francesco Toschi Glyn Ellis 杨秋霜 | 2008 | 钢铁2008,43,10: | 4 |
| 8 | 视知觉组织在整体知觉中的作用——脑损伤病人的实验研究显示文摘本实验研究大脑损伤如何影响复合图形的整体知觉。三例病人脑损伤部位分别在大脑枕区、顶区、颞区、额区及基底节和豆状核。复合图形被呈现给病人和正常对照被试。强迫选择识别等任务表明 ,当空间相邻性决定局部图形的知觉组织时 ,病人识别整体性质的正确率高于 (ZD和FL)或略底于 (GK)识别局部性质的正确率 ;当形状相似性决定局部图形的知觉组织时 ,病人识别整体性质的正确率显著降低 ,而识别局部性质的正确率受到的影响较小。在同样的任务中正常被试识别整体和局部性质的正确率受知觉组织因素的影响很小。 | 韩世辉 Glyn W.Humphreys 周华民 王东刚 | 2002 | 心理科学2002,25,4: | 2 |
| 9 | Methylation of TIMP3 in esophageal squamous cell carcinoma显示文摘AIM: To measure the frequency of DNA methylation of the tissue inhibitor of metalloproteinase 3 (TIMP3) promoter and relate this to any change of gene expression in esophageal squamous cell carcinoma in patients from a region of high incidence in China.METHODS: Cancer cell lines were treated with or without the demethylating reagent 5-aza-2’-deoxycytidine. Methylation of the TIMP3 promoter was assessed in three regions by melt curve analysis and its expression was assessed by real-time RT-PCR. Tumors and proximal resection margins were obtained from 64 patients with esophageal squamous cell carcinoma from a region of high incidence in China. Methylation was assessed by melt curve analysis and expression by immunohistochemistry.RESULTS: Methylation in one of the three promoter regions assessed correlated with gene silencing in esophageal cell lines. A degree of methylation of TIMP3 was found in only four esophageal squamous cell carcinomas, and partial loss of TIMP3 protein expression in just one.CONCLUSION: Methylation and loss of expression of TIMP3 occurs infrequently in esophageal squamous cell carcinoma in a region of high incidence in China. | Eric Smith Neville J De Young Zi-Qiang Tian Maria Caruso Andrew R Ruszkiewicz Jun-Feng Liu Glyn G Jamieson Paul A Drew | 2008 | World Journal of Gastroenterology2008,14,2: | 2 |
| 10 | Watching cartoons activates the medial prefrontal cortex in children显示文摘The medial prefrontal cortex (MPFC) of human adults is involved in attributing mental states to real human agents but not to virtual artificial characters. This study examined whether such differential MPFC activity can be observed in children who are more fascinated by cartoons than adults. We measured brain activity using functional magnetic resonance imaging (fMRI) while 10-year-old children watched movie and cartoon clips, simulating real and virtual visual worlds, respectively. We showed neuroimaging evidence that, in contrast to adults, the MPFC of children was activated when perceiving both human agents and artificial characters in coherent visual events. Our findings suggest that, around the age of 10 years, the MPFC activity in children is different from that in adults in that it can be spontaneously activated by non-human agents in a virtual visual world. | HAN ShiHui JIANG Yi Glyn W. HUMPHREYS | 2007 | Chinese Science Bulletin2007,52,24: | 2 |
| 11 | 'Doing prescribing':how doctors can be more effective显示文摘 | Glyn Elwyn Adrian Edwards Nicky Brittem | 2003 | BMJ2003,327,7419: | 1 |
| 12 | Postsurgical Infections are Reduced with Specialized Nutrition Support显示文摘 | Dan L. Waitzberg Hideaki Saito Lindsay D. Plank Glyn G. Jamieson Palepu Jagannath Tsann-Long Hwang Juan M. Mijares David Bihari | 2006 | World Journal of Surgery2006,,8: | 1 |
| 13 | The International Atomic Energy Agency (IAEA) Programme in Radiation and Tissue Banking: Past, Present and Future显示文摘 | Glyn O. Phillips Jorge M. Pedraza | 2003 | Cell and Tissue Banking2003,,: | 1 |
| 14 | A review of isolation process, structural characteristics, and bioactivities of water-soluble polysaccharides from Dendrobium plants显示文摘 | Xiaohui Xing Steve W. Cui Shaoping Nie Glyn O. Phillips H. Douglas Goff Qi Wang | 2013 | Bioactive Carbohydrates and Dietary Fibre2013,,2: | 1 |
| 15 | Peritumoral diffusion tensor imaging of high-grade gliomas and metastatic brain tumors显示文摘 | Stanley L Daniel A Glyn J | 2003 | AJNR2003,24,5: | 1 |
| 16 | 基于规则和基于相似性的分类学习在复杂视觉分类中的比较显示文摘采用同一复杂视觉分类任务,通过比较对基于规则的和基于相似性的分类学习异同,探讨了2种不同分类过程之间的相互关系,结果发现:在不同感知类型的刺激项目上,基于相似性的分类成绩都明显高于基于规则的分类成绩.在基于相似性的分类学习模式下,不同感知难度的刺激正确率之间都存在显著差异;在基于规则的分类学习模式下,部分类型的刺激正确率之间不存在明显差异.实验结果表明基于规则的和基于相似性的2种不同加工过程同时存在于同一分类过程中并且互相作用,研究支持了多系统理论模型. | 谢伟 Glyn Humphreys | 2012 | 西南师范大学学报(自然科学版)2012,37,6: | 1 |
| 17 | Laying the Cytotaxonomic Foundations of a New Model Grass, Brachypodium distachyon (L.) Beauv.显示文摘 | Robert Hasterok John Draper Glyn Jenkins | 2004 | Chromosome Research2004,,4: | 1 |
| 18 | Cuyoanalgesia:a new approach to pain welief显示文摘 | Ltlyd JW Barnard JD Glyn CJ | 1976 | Lancet1976,2,1992: | 1 |
| 19 | Immunology of diseases associated with Malassezia species 显示文摘 | Ashbee HR Glyn E Evans V | 2002 | Clinical Microbiology Reviews2002,15,: | 1 |
| 20 | Division of Short Gastric Vessels at Laparoscopic Nissen Fundoplication: A Prospective Double-Blind Randomized Trial With 5-Year Follow-Up显示文摘 | Colm J. O’Boyle David I. Watson Glyn G. Jamieson Jennifer C. Myers Philip A. Game Peter G. Devitt | 2002 | Annals of Surgery2002,,2: | 1 |