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		题名	作者	年代	出处	被引量
	1	Multiplex RT-PCR-based detections of CEA, CK20 and EGFR in colorectal cancer patients显示文摘AIM: To develop a multiplex reverse transcription polymerase chain reaction (RT-PCR) method detecting cir-culating tumor cells in the peripheral blood of colorectal cancer (CRC) patients. METHODS: Peripheral blood samples were collected from 88 CRC patients and 40 healthy individuals from the blood donors' clinic and subsequently analyzed by multiplex RT-RCR for the expression of carcinoembryonic antigen (CEA), cytokeratin 20 (CK20) and epidermal growth factor receptor (EGFR) mRNA. The analysis involved determining the detection rates of CEA, CK20 and EGFR transcripts vs disease stage and overall survival. Median follow-up period was 19 mo (range 8-28 mo). RESULTS: Rates of CEA, CK20 and EGFR detection in CRC patients were 95.5%, 78.4% and 19.3%, respectively. CEA transcripts were detected in 3 healthy volunteer samples (7.5%), whereas all control samples were tested negative for CK20 and EGFR transcripts. The increasing number of positive detections for CEA, CK20 and EGFR transcripts in each blood sample was positively correlated with Astler-Coller disease stage (P< 0.001) and preoperative serum levels of CEA (P=0.029) in CRC patients. Data analysis using Kaplan-Meier estimator documented signif icant differences in the overall survival of the different CRC patient groups as formed according to the increasing number of positivity for CEA, CK20 and EGFR transcripts. CONCLUSION: These data suggest that multiplex RTPCR assay can provide useful information concerning disease stage and overall survival of CRC patients.	Aikaterini Tsouma Chrysanthi Aggeli Panagiotis Lembessis George N Zografos Dimitris P Korkolis Dimitrios Pectasides Maria Skondra Nikolaos Pissimissis Anastasia Tzonou Michael Koutsilieris	2010	World Journal of Gastroenterology2010，16，47：	19
	2	Paclitaxel and carboplatin as first-line chemotherapy combined with gefitinib (IRESSA) in patients with advanced breast cancer: a phase I/II study conducted by the Hellenic Cooperative Oncology Group显示文摘	George Fountzilas Dimitrios Pectasides Anna Kalogera-Fountzila Dimosthenis Skarlos Haralambos P. Kalofonos Christos Papadimitriou Dimitrios Bafaloukos Stefanos Lambropoulos Savvas Papadopoulos Helen Kourea Christos Markopoulos Helen Linardou Dimitrios Mav	2005	Breast Cancer Research and Treatment2005，，1：	1
	3	Improved Outcome of High-Risk Early HER2 Positive Breast Cancer With High CXCL13-CXCR5 Messenger RNA Expression显示文摘	Evangelia Razis Konstantine T. Kalogeras Vassiliki Kotoula Anastasia G. Eleftheraki Nikitas Nikitas Ralf Kronenwett Eleni Timotheadou Christos Christodoulou Dimitrios Pectasides Helen Gogas Ralph M. Wirtz Thomas Makatsoris Dimitrios Bafaloukos Gerasimos A	2012	Clinical Breast Cancer2012，，3：	1
	4	Increasing frequency of gram‐positive cocci and gram‐negative multidrug‐resistant bacteria in spontaneous bacterial peritonitis显示文摘	Alexandra Alexopoulou Nikolaos Papadopoulos Dimitrios G. Eliopoulos Apostolia Alexaki Athanasia Tsiriga Marina Toutouza Dimitrios Pectasides	2013	Liver Int2013，，7：	1
	5	Advanced stage clear-cell epithelial ovarian cancer: The Hellenic cooperative oncology group experience显示文摘	Dimitrios Pectasides George Fountzilas Gerassimos Aravantinos Charalambos Kalofonos Helen Efstathiou Dimitrios Farmakis Dimosthenes Skarlos Nikolaos Pavlidis Theofanis Economopoulos Meletios A. Dimopoulos	2006	Gynecologic Oncology2006，，：	1
	6	Gemcitabine versus Gemcitabine–Carboplatin for Patients with Advanced Non-small Cell Lung Cancer and a Performance Status of 2: A Prospective Randomized Phase II Study of the Hellenic Cooperative Oncology Group显示文摘	Paris A. Kosmidis Meletios-Athanasios Dimopoulos Konstantinos Syrigos Costas Nicolaides Gerasimos Aravantinos Ioannis Boukovinas Dimitrios Pectasides George Fountzilas Dimitrios Bafaloukos Charalampos Bacoyiannis Haralampos P. Kalofonos	2007	Journal of Thoracic Oncology2007，，2：	1
	7	Molecularly targeted therapies in unresectable-metastatic gastric cancer. A systematic review显示文摘	Flora Zagouri Christos A. Papadimitriou Meletios-Athanassios Dimopoulos Dimitrios Pectasides	2011	Cancer Treatment Reviews2011，，8：	1
	8	XELOX versus FOLFOX6 as an adjuvant treatment in eoloreetal cancer: an economic analysis显示文摘	Maniadakis Nikos Fragoulakis Vasilios Pectasides Dimitrios	2009	Current Medical Research and Opinion2009，25，3：	1

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