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| 1 | Adenomyomatosis of the gallbladder in childhood: A systematic review of the literature and an additional case report显示文摘AIM: To investigate the diagnostic and therapeutic assessment in children with adenomyomatosis of the gallbladder(AMG).METHODS: AMG is a degenerative disease characterized by a proliferation of the mucosal epithelium which deeply invaginates and extends into the thickened muscular layer of the gallbladder, causing intramural diverticula. Although AMG is found in up to 5% of cholecystectomy specimens in adult populations, this condition in childhood is extremely uncommon. Authors provide a detailed systematic review of the pediatric literature according to PRISMA guidelines, focusing on diagnostic and therapeutic assessment. An additional case of AMG is also presented. RESULTS:Five studies were finally enclosed, encompassing 5 children with AMG. Analysis was extended to our additional 11-year-old patient, who presented diffuse AMG and pancreatic acinar metaplasia of the gallbladder mucosa and was successfully managed with laparoscopic cholecystectomy. Mean age at presentation was 7.2 years. Unspecific abdominal pain was the commonest symptom. Abdominal ultrasound was performed on all patients, with a diagnostic accuracy of 100%. Five patients underwent cholecystectomy, and at follow-up were asymptomatic. In the remaining patient, completely asymptomatic at diagnosis, a conservative approach with monthly monitoring via ultrasonography was undertaken. CONCLUSION: Considering the remote but possible degeneration leading to cancer and the feasibility of laparoscopic cholecystectomy even in small children, evidence suggests that elective laparoscopic cholecystectomy represent the treatment of choice. Preoperative evaluation of the extrahepatic biliary tree anatomy with cholangio-MRI is strongly recommended. | Filippo Parolini Giuseppe Indolfi Miguel Garcia Magne Marianna Salemme Maurizio Cheli Giovanni Boroni Daniele Alberti | 2016 | World Journal of Clinical Pediatrics2016，5，2： | 6 |
| 2 | Inflammatory fibroid polyps in children:A new case report and a systematic review of the pediatric literature显示文摘AIM: To study that inflammatory fibroid polyps(IFPs) in children are extremely uncommon tumors that may occur throughout the gastrointestinal tract. METHODS: A systematic review of the pediatric literature and a report of a new case of IFP is also pres-ented. The Pub Med database was searched for original studies on pediatric IFPs since 1960, according to 'Preferred reporting items for systematic reviews and meta-analyses' guidelines for systematic reviews. RESULTS: Five studies were finally enclosed, encompassing 6 children with IFPs(mean age 64 mo). Tumors were located in the stomach(2 patients), in the small bowel(2 patients), in the rectum(1 patient) and in the colon(1 patient). Open surgery was performed in all patients and complete excision of the mass was achieved in all cases. All patients are alive and free of symptom. Authors described a further case of a 3-year-old boy with a large duodenal IFP, in whom the tumor was removed by 'en block resection'. The presence of IFP throughout the gastrointestinal tract and its variable clinical appearances make it difficult to diagnose. An accurate pre-operative assessment is fundamental in order to differentiate IFP from other more aggressive gastrointestinal tumor, enabling unnecessary demolitive surgery. CONCLUSION: When complete resection of the IFP is achieved, the prognosis is excellent. | Laura Righetti Filippo Parolini Paolo Cengia Giovanni Boroni Maurizio Cheli Aurelio Sonzogni Daniele Alberti | 2015 | World Journal of Clinical Pediatrics2015，4，4： | 5 |
| 3 | Isolation andcharacterization cells from human term placenta : outcomeof the first international workshop on plancenta derived stemcells显示文摘 | Parolini 0 Alviano F Bagnara GP | 2008 | Stem Cells2008，26，： | 1 |
| 4 | Postoperative complications and intraocular pressure in 943 consecutive cases of 23-gauge transconjunctival pars plans vitrectomy with 1-year follow-up显示文摘 | Parolini B Prigione G Romanelli F | | 0，，： | 1 |
| 5 | Environmental Regulation and Investment: Evidence from European Industry Data 显示文摘 | Leiter A M Parolini A Winner H | 2011 | Ecological Economics2011，70，04： | 1 |
| 6 | IL -21 induces bothrapid maturation of human CD34+ cell precursors towardsNK cells and acquisition of surface killer Ig-like receptors显示文摘 | Sivori S Cantoni C Parolini S | 2003 | Eur J Immunol2003，33，12： | 1 |
| 7 | The role of chemerin in the colocalization of NK and dendritic cell subsets into inflamed tissues显示文摘 | Parolini S Santoro A Marcenaro E | 2007 | Blood2007，109，9： | 1 |
| 8 | Analysis of SH2D1A mutations in patients with severe Epstein-Barr virus infections,Burkitt's lymphoma,and Hodgkin's lymphoma显示文摘 | Parolini O Kagerbauer B Simonitsch-Klupp I | | 0，，08： | 1 |
| 9 | Microenvironmental pH is a key factor for exosome traffic in tumor cells显示文摘 | Parolini I Federiei C Raggi C | 2009 | J Biol Chem2009，284，34： | 1 |
| 10 | Chronic effects induced by ibu-profen on the freshwater bivalve Dreissena polymorpha 显示文摘 | Parolini M Binelli A Provini A | 2011 | Eco-toxicology and Environmental Safety2011，74，6： | 1 |
| 11 | Hydroepithelial keratectomy in rabbits with a waterjet-based instrument显示文摘 | Parolini B Turdiu P Abelson M | 1998 | J Refract Surg1998，14，3： | 1 |
| 12 | Identification and molecular characterization of NKp30,a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells显示文摘 | Pende D Parolini S Pessino A | 1999 | J Exp Med1999，190，10： | 1 |
| 13 | Inhibition of TPO-induced MEK or roTOR activity induces opposite effects on the ploidy of human differentiating mcgakaryocytes 显示文摘 | GUERRIERO R PAROLINI I TESTA U | 2006 | J Cell Sci2006，119，4： | 1 |
| 14 | Identification and molecular characterization of NKp30,a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells显示文摘 | Pende D Parolini S Pessino A | 1999 | J Exp Med1999，190，10： | 1 |
| 15 | Renal resistive index and long- term outcome in chronic nephropathies显示文摘 | Parolini C Noce A Staffolani E | 2009 | Radiology2009，252，3： | 1 |
| 16 | Mesenchymal Stem/Stromal Cells: A New ’’Cells as Drugs’’ Paradigm. Efficacy and Critical Aspects in Cell Therapy显示文摘 | Laura de Girolamo Enrico Lucarelli Giulio Alessandri Maria Antonietta Avanzini Maria Ester Bernardo Ettore Biagi Anna Teresa Brini Giovanna D’Amico Franca Fagioli Ivana Ferrero Franco Locatelli Rita Maccario Mario Marazzi Ornella Parolini Augusto Pessina | 2013 | Current Pharmaceutical Design2013，，： | 1 |
| 17 | The role of chemerin in the colocalization of NK and dendritic cell subsets into inflamed tissues显示文摘 | Parolini S Santoro A Marcenaro E | 2007 | Blood2007，109，9： | 1 |
| 18 | NK cells at the interfacebetween innate and adaptive immunity显示文摘 | Moretta A Marcenaro E Parolini S | 2008 | Cell Death Differ2008，15，2： | 1 |
| 19 | Renal resistive index and Long-- term outcome in chronic nephropathies显示文摘 | ParoLini C Noee A Staffo/ani E | 2009 | Radiology2009，252，3： | 1 |
| 20 | Concise review: isolation and characterization of cells from human term placentas outcome of the first international Workshop on Placenta Derived Stem Cells显示文摘 | PAROLINI O ALVIANO F BAGNARA G | 2007 | Stem Ceils2007，26，2： | 1 |
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