|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming显示文摘新陈代谢对房间功能的每个方面重要,然而,导致的 pluripotent 干细胞(iPSCs ) 的 metabolome 仍然保持大部分未经勘探。这里,我们报导,用一条 untargeted metabolomics 途径,那人的 iPSCs 份额有从他们的父母房间是不同的胚胎的干细胞(转换字符) 的 pluripotent metabolomic 签名,并且那被变化在涉及细胞的呼吸的代谢物描绘。细胞的 bioenergetics 的检查与我们的 metabolomic 分析支持了,并且证明体的房间在 pluripotency 从一个氧化状态变换成一个 glycolytic 状态。有趣地,各种各样的体的房间的 bioenergetics 与他们的 reprogramming 效率相关。我们进一步识别了在 iPSCs 和转换字符之间不同的代谢物,它揭示了在调整体的房间 reprogramming 起一个关键作用的新奇新陈代谢的小径。我们的调查结果是第一全球性分析 iPSCs 的 metabolome,并且提供机械学的卓见进涉及导致 pluripotency,并且在评估 iPSC 和转换字符等价的规定的新层。 | Athanasia D Panopoulos Oscar Yanes Sergio Ruiz Yasuyuki S Kida Dinh Diep Ralf Tautenhahn Aida Herrerias Erika M Batchelder Nongluk Plongthongkum Margaret Lutz W Travis Berggren Kun Zhang Ronald M Evans Gary Siuzdak Juan Carlos Izpisua Belmonte] | 2012 | Cell Research2012，22，1： | 12 |
| 2 | T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ显示文摘 | Xuexian O. Yang Bhanu P. Pappu Roza Nurieva Askar Akimzhanov Hong Soon Kang Yeonseok Chung Li Ma Bhavin Shah Athanasia D. Panopoulos Kimberly S. Schluns Stephanie S. Watowich Qiang Tian Anton M. Jetten Chen Dong | 2008 | Immunity2008，，1： | 3 |
| 3 | STAT3regulates cytokine-mediated generation of inflammatory helper T cells显示文摘 | Yang X O Panopoulos A D Nurieva R | 2007 | Biol Chem2007，282，13： | 1 |
| 4 | STAT3 regulates cytokine-medi- ated generation of inflammatory helper T cells 显示文摘 | Yang XO Panopoulos AD Nurieva R | 2007 | J Biol Chem2007，282，13： | 1 |
| 5 | STAT3 regulates cytokine-mediated generation of inflammatory helper T cells显示文摘 | Yang XO Panopoulos AD Nurieva R | 2007 | J Biol Chem2007，282，13： | 1 |
| 6 | STAT3 controls myeloid progenitor growth during emergency granulopoiesis显示文摘 | Zhang H Nguyen-Jackson H Panopoulos AD | 2010 | Blood2010，116，14： | 1 |
| 7 | STA33 regu lares cytokine-mediated generation of inflammatory helper T ceils 显示文摘 | Yang XO Panopoulos AD Nurieva R | 2007 | J Biol Chem2007，282，13： | 1 |
| 8 | STAT3 regulates cytokine- mediated generation of Inflammatory helper T cells 显示文摘 | Yang XO Panopoulos AD Nurieva R | 2007 | J Biol Chem2007，282，13： | 1 |
| 9 | STAT3 regulates cy-tokine-mediated generation of inflammatory helper T cells 显示文摘 | Yang XO Panopoulos AD Nurieva R | 2007 | J Biol Chemi2007，282，13： | 1 |
| 10 | STAT3regulates cytokine-mediated generation of inflammatory helper T cells显示文摘 | Yang XO Panopoulos AD Nurieva R WangD | 2007 | J Biol Chem2007，282，： | 1 |
| 11 | Biological treatments andconnective tissue disease associated interstitial lungdisease显示文摘 | Panopoulos ST Sfikakis PP | 2011 | Curr Opin Pulm Med2011，17，5： | 1 |
| 12 | Metabolic engineeringof the complete pathway leading to heterologous biosynthesisof various flavonoids and stilbenoids in Saccharomycescerevisiae 显示文摘 | Trantas E Panopoulos N Ververidis F | 2009 | Metab Eng2009，11，6： | 1 |
| 13 | Granulocyte colony-stimulating fac- tor: molecular mechanisms of action during steady state and ' emer- gency'hematopoiesis 显示文摘 | Panopoulos AD Watowich SS | 2008 | Cytokine2008，42，3： | 1 |
| 14 | Agglomera-tion in fluidised bed gasification of biomass 显示文摘 | Fry da L E Panopoulos K D Kakaras E | 2007 | PowderTechnology2007，179，： | 1 |
| 15 | STAT3 regulates cytokine-mediated generation of inflammatory helper T cells显示文摘 | Yang XO Panopoulos AD Nurrieva R | 2007 | J Biol Chem2007，282，13： | 1 |
| 16 | Expression of a bacterial ice nteleation gene in plants 显示文摘 | Baertlein D A Lindow S E Panopoulos N J | 1992 | Plant Physiology1992，100，4： | 1 |
| 17 | Glioblastoma motility occurs in the absence of actin polymer显示文摘 | Panopoulos A Howell M Fotedar R | 2011 | Mol Biol Cell2011，22，13： | 1 |
| 18 | STAT3 regulates cy- tokine-mediated generation of inflammatory helper T cells 显示文摘 | Yang X O Panopoulos A D Nurieva R | 2007 | J Biol Chem2007，282，13： | 1 |
| 19 | The Influence of the Olympic Games on Beijing Consumer' Perceptions of Their City Tourism Development 显示文摘 | Kapareliotis I Panopoulos A Panigyrakis G G | 2010 | Asia Pacific Journal of Marketing and Logistics2010，22，1： | 1 |
| 20 | Comparing calcined and un-treated olivine as bed materials for tar reduction in fluidized bed gasification 显示文摘 | CHRISTODOULOU C GRIMEKIS D PANOPOULOS K D PACHATOURIDOU E P ILIOPOULOU E F KAKARAS E | 2014 | Fuel Process Technol2014，124，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员