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| 1 | The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: Definitions and diagnosis显示文摘 | Gert Van Assche Axel Dignass Julian Panes Laurent Beaugerie John Karagiannis Mathieu Allez Thomas Ochsenkühn Tim Orchard Gerhard Rogler Edouard Louis Limas Kupcinskas Gerassimos Mantzaris Simon Travis Eduard Stange | 2009 | Journal of Crohn’s and Colitis2009，，1： | 10 |
| 2 | 中国和东盟国家常用传统药物治疗糖尿病及其并发症药理作用的研究进展显示文摘糖尿病是一种由于体内胰岛素绝对或相对分泌不足而引起的以糖代谢紊乱为主的全身性疾病,严重威胁人类的身心健康,而中国和东盟地区更是糖尿病高发地区,患病人数居全球第1位。通过查阅《中国-东盟传统药物志》,中国和东盟国家用于治疗糖尿病、消渴症的传统药物有81种,其中在中国和东盟国家中应用较为广泛且研究较为深入的有25种。利用中国知网、维普、Pubmed等数据库系统地查阅和整理国内外关于25种传统药物治疗糖尿病及其并发症的相关文献,对25种药物降血糖药理作用及其作用机制进行综述,传统药物改善糖尿病及其并发症的作用机制主要是通过抑制炎症及过氧化反应,调节糖脂,改善胰岛素抵抗,提高胰岛素敏感性,修复胰岛细胞,促进胰岛素分泌等途径,可为开发安全、有效的降糖药以及加强中国和东盟国家进一步的研究合作提供有益的参考。 | 李意春 郝二伟 刘婧曦 杜正彩 白钢 张铁军 Wattanathorn Jintanaporn Sirisaard Panee Tang Pei-ling 侯小涛 邓家刚 刘昌孝 | 2021 | 中草药2021，52，4： | 8 |
| 3 | Agricultural Risk Modeling Challenges in China:Probabilistic Modeling of Rice Losses in Hunan Province显示文摘This article summarizes a joint research projec undertaken under the Risk Management Solutions, Inc(RMS) banner to investigate some of the possible approaches for agricultural risk modeling in China. Two modeling approaches were investigated—the simulated weather crop index and the burn yield analysis approach. The study was limited to Hunan Province and a single crop—rice. Both modeling approaches were dealt with probabilistically and were able to produce probabilistic risk metrics. Illustrative model outputs are also presented. The article discusses the robustness of the modeling approaches and their dependence on the availability, access to, and quality of weather and yield data. We offer our perspective on the requirements for models and platforms for agricultural risk quantification in China in order to respond to the needs of all stakeholders in agricultural risk transfer. | Pane Stojanovski Weimin Dong Ming Wang Tao Ye Shuangcai Li Christian P.Mortgat | 2015 | International Journal of Disaster Risk Science2015，6，4： | 5 |
| 4 | Burden and outcomes for complex perianal fistulas in Crohn's disease:Systematic review显示文摘AIM To systematically review the literature on epidemiology,disease burden, and treatment outcomes for Crohn's disease(CD) patients with complex perianal fistulas.METHODS PubMed, Embase, and Cochrane were searched for relevant articles(published 2000-November 2016) and congress abstracts(published 2011-November 2016).RESULTS Of 535 records reviewed, 62 relevant sources were identified(mostly small observational studies). The cumulative incidence of complex perianal fistulas in CD from two referral-centre studies was 12%-14%(follow-up time, 12 years in one study; not reported in the second study). Complex perianal fistulas result in greatly diminished quality of life; up to 59% of patients are at risk of faecal incontinence. Treatments include combinations of medical and surgical interventions and expanded allogeneic adipose-derived stem cells. High proportions of patients experience lack of or inadequate response to treatment(failure and relapse rates,respectively: medical, 12%-73% and 0%-41%; surgical:0%-100% and 11%.20%; combined medical/surgical:0%-80% and 0%-50%; stem cells: 29%-47% and not reported). Few studies(1 of infliximab; 3 of surgical interventions)have been conducted in treatment-refractory patients, a population with high unmet needs. Limited data exist on the clinical value of anti-tumour necrosis factor-α dose escalation in patients with complex perianal fistulas in CD.CONCLUSION Complex perianal fistulas in CD pose substantial clinical and humanistic burden. There is a need for effective treatments, especially for patients refractory to antitumour necrosis factor-α agents, as evidenced by high failure and relapse rates. | Julian Panes Walter Reinisch Ewa Rupniewska Shahnaz Khan Joan Forns Javaria Mona Khalid Daniela Bojic Haridarshan Patel | 2018 | World Journal of Gastroenterology2018，24，42： | 5 |
| 5 | 脾对比增强复合谐波超声检查对于提高霍奇金淋巴瘤病人的分期准确性:前瞻性研究显示文摘目的前瞻性比较对比增强复合谐波超声(US)、CT、18-氟脱氧葡萄糖正电子发射断层显像(FDG—PET)对初诊霍奇金淋巴瘤病人脾结节样浸润的检出效果。方法经机构审查委员会批准,病人知情同意后,在对连续100例霍奇金淋巴瘤病人进行治疗前分期,探查脾是否受累时,前瞻性比较复合谐波超声(33例病人静脉注射微泡对比剂)与CT、FDG—PET的检查结果。以上影像学手段发现恶性结节的提示征象时认为是淋巴瘤浸润;对于存在争议的病灶, | M. Picardi A. Soricelli F. Pane P. Zeppa E. Nicolai M. De Laurentiis 李瑞利(译) 沈文(校) | 2009 | 国际医学放射学杂志2009，32，4： | 5 |
| 6 | Anethum graveolens Linn.(dill) extract enhances the mounting frequency and level of testicular tyrosine protein phosphorylation in rats显示文摘Objective:To investigate the effect of Anethum graveolens(AG) extracts on the mounting frequency,histology of testis and epididymis,and sperm physiology.Methods:Male rats induced by cold immobilization before treating with vehicle or AG extracts [50,150,and 450 mg/kg body weight(BW)] via gastric tube for consecutive 1,7,and 14 d were examined for mounting frequency,testicular phosphorylation level by immunoblotting,sperm concentration,sperm acrosome reaction,and histological structures of testis and epididymis,respectively.Results:AG(50 mg/kg BW) significantly increased the mounting frequency on Days 1 and 7 compared to the control group.Additionally,rat testis treated with 50 mg/kg BW AG showed high levels of phosphorylated proteins as compared with the control group.In histological analyses,AG extract did not affect the sperm concentration,acrosome reaction,and histological structures of testis and epididymis.Conclusions:AG extract enhances the aphrodisiac activity and is not harmful to sperm and male reproductive organs. | Sitthichai IAMSAARD Thawatchai PRABSATTROO Wannisa SUKHORUM Supaporn MUCHIMAPURA Panee SRISAARD Nongnut UABUNDIT Wipawee THUKHAMMEE Jintanaporn WATTANATHORN | 2013 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2013，14，3： | 4 |
| 7 | Second European evidence-based consensus on the diagnosis and management of ulcerative colitis: Special situations显示文摘 | Gert Van Assche Axel Dignass Bernd Bokemeyer Silvio Danese Paolo Gionchetti Gabriele Moser Laurent Beaugerie Fernando Gomollón Winfried H?user Klaus Herrlinger Bas Oldenburg Julian Panes Francisco Portela Gerhard Rogler Jürgen Stein Herbert Tilg Simon Tra | 2012 | Journal of Crohn’s and Colitis2012，，： | 4 |
| 8 | Evolution of seismic risk management for insurance over the past 30 years显示文摘During the past 30 years, there has been spectacular growth in the use of risk analysis and risk management tools developed by engineers in the financial and insurance sectors. The insurance, the reinsurance, and the investment banking sectors have enthusiastically adopted loss estimation tools developed by engineers in developing their business strategies and for managing their financial risks. As a result, insurance/reinsurance strategy has evolved as a major risk mitigation tool in managing catastrophe risk at the individual, corporate, and government level. This is particularly true in developed countries such as US, Western Europe, and Japan. Unfortunately, it has not received the needed attention in developing countries, where such a strategy for risk management is most needed. Fortunately, in the last five years, there has been excellent focus in developing 'Insur Tech' tools to address the much needed 'Insurance for the Masses', especially for the Asian Markets. In the earlier years of catastrophe model development, risk analysts were mainly concerned with risk reduction options through engineering strategies, and relatively little attention was given to financial and economic strategies. Such state-of-affairs still exists in many developing countries. The new developments in the science and technologies of loss estimation due to natural catastrophes have made it possible for financial sectors to model their business strategies such as peril and geographic diversification, premium calculations, reserve strategies, reinsurance contracts, and other underwriting tools. These developments have not only changed the way in which financial sectors assess and manage their risks, but have also changed the domain of opportunities for engineers and scientists.This paper will address the issues related to developing insurance/reinsurance strategies to mitigate catastrophe risks and describe the role catastrophe risk insurance and reinsurance has played in managing financial risk due to natural catastrophes. Historical losses and the share of those losses covered by insurance will be presented. How such risk sharing can help the nation share the burden of losses between tax paying public, the 'at risk' property owners, the insurers and the reinsurers will be discussed. The paper will summarize the tools that are used by the insurance and reinsurance companies for estimating their future losses due to catastrophic natural events. The paper will also show how the results of loss estimation technologies developed by engineers are communicated to the business flow of insurance/reinsurance companies. Finally, to make it possible to grow 'Insurance for the Masses – IFM', the role played by parametric insurance products and Insur Tech tools will be discussed. | Haresh C.Shah Weimin Dong Pane Stojanovski Alex Chen | 2018 | Earthquake Engineering and Engineering Vibration2018，17，1： | 3 |
| 9 | Imaging techniques for assessment of inflammatory bowel disease: Joint ECCO and ESGAR evidence-based consensus guidelines显示文摘 | J. Panes Y. Bouhnik W. Reinisch J. Stoker S.A. Taylor D.C. Baumgart S. Danese S. Halligan B. Marincek C. Matos L. Peyrin-Biroulet J. Rimola G. Rogler G. van Assche S. Ardizzone A. Ba-Ssalamah M.A. Bali D. Bellini L. Biancone F. Castiglione R. Ehehalt R. G | 2013 | Journal of Crohn’s and Colitis2013，，7： | 2 |
| 10 | Effects of chronic arterial hypertension on constitutive and induced intercellular adhesion molecule-1 expression in vivo显示文摘 | Komatsu S Panes J Russell JM | 1997 | Hypertension1997，29，2： | 2 |
| 11 | Investigation of blended cement hydration by isothermal calorimetry and thermal analysis显示文摘 | Ivindra Pane Will Hansen | 2005 | Cement and Concrete Research2005，，6： | 2 |
| 12 | Statin Treatment Is Associated with Reduction in Serum Levels of Receptor Activator of NF- κ B Ligand and Neutrophil Activation in Patients with Severe Carotid Stenosis显示文摘 | Sébastien Lenglet Alessandra Quercioli Mathias Fabre Katia Galan Graziano Pelli Alessio Nencioni Inga Bauer Aldo Pende Magaly Python Maria Bertolotto Giovanni Spinella Bianca Pane Domenico Palombo Franco Dallegri Fran?ois Mach Nicolas Vuilleumier Fabrizio | 2014 | Mediators of Inflammation2014，，： | 2 |
| 13 | Errored block detection with bit interleaved parity failures in SDH network显示文摘 | Pane P Spini M | 1995 | IEEE Transaction on Communications1995，43，12： | 1 |
| 14 | Diabetes exacerbates in- flammatory response to isehemia-reperfusion 显示文摘 | Panes J Krose L Rodriguez VD | 1996 | Circulation1996，93，： | 1 |
| 15 | Health-related quality of life measurement in children and adolescents: a systematic review of generic and disease-specific instruments显示文摘 | Solans M Pane S Estrada MD | 2008 | Value Health2008，11，4： | 1 |
| 16 | Fas-mediated modulation of Bcr/abl in chronic myelogenous leukemia results in differetial effects on apoptosis显示文摘 | Maciejewski JP Pane F | 1998 | Blood1998，92，： | 1 |
| 17 | Identifying differences in biased affective information processing in major depression显示文摘 | Gollan JK Pane HT McCloskey MS | 2008 | Psychiatry Res2008，159，： | 1 |
| 18 | Effect of bolus injection and continuous infusion of somatostafin on gastric perfusion in cirrhotic patients with portal - hypertensive gastropathy显示文摘 | Panes J Pique JM Bordas JM | 1994 | Hepatology1994，20，： | 1 |
| 19 | The role of BCR/ABL isoforms in the presentation and outcome of patients with Philadelphia - positive acute lymphoblastic leukemia:a seven - year update of the GIMEMA 0496 trial 显示文摘 | Cimino G Pane F Elia L | 2006 | Haematologica2006，91，3： | 1 |
| 20 | Preconditioning protects against systemic disorders associated with hepatic ischemia-reperfusion through blockade of tumor necrosis factor-induced P-selectin up-regulation in the rat显示文摘 | Peralta C Fernandez L Panes J | 2001 | Hepatology2001，33，： | 1 |
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