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| 1 | Liver transplantation in patients with portal vein thrombosis显示文摘 | Gerardo Manzanet Fernando Sanjuán Paco Orbis Rafael López ángel Moya Manuel Juan Juanjo Vila Josep Asensi Pedro Sendra José Ru??z Mart??n Prieto José Mir | 2001 | Liver Transplantation2001，，2： | 1 |
| 2 | MHC classⅠmolecules act as tumor suppressor genes regulating the cell cycle gene expression,invasion and intrinsic tumorigenicity of melanoma cells显示文摘 | Garrido C Paco L Romero I | 2012 | Carcinogenesis2012，33，3： | 1 |
| 3 | Thyroid carcinoma in children and adolescents:a retrospective review显示文摘 | Neiva F Mesquita J Paco Lima S | | 0，，： | 1 |
| 4 | Inducible nitric oxide synthase polymorphism is associated with susceptibility to Henoch-Schonlein purpura in northwestern Spain显示文摘 | Paco L Ruiz MP | 2005 | J Rheumatol2005，32，6： | 1 |
| 5 | The patients with severe chronic obstructive pulmonary disease and chronic respiratory insufficiency 显示文摘 | Ambrosino N Di Giorgio M Di Paco A | 2007 | Monaldi Arch Chest Dis2007，67，3： | 1 |
| 6 | 难治性类风湿关节炎的临床特点:一项国际问卷调查研究显示文摘目的尽管按照目前欧洲抗风湿联盟(EULAR)的推荐对类风湿关节炎(rheumatoid arthritis,RA)患者进行治疗,难治性RA患者的临床症状却仍然没有得到完全控制,目前EULAR指南主要关注的是RA的早期治疗和药物治疗。本研究的目的在于分析难治性RA患者的临床特点,以及在患者管理中需要探索然而现有EULAR指南并未涉及的问题。方法对多个国家的风湿科医生进行问卷调查,分析难治性RA的临床特点。问卷包括多选题以及开放性问题,从开放性问题的回答中发现需要进一步阐明的问题以及现有EULAR指南需要增加的内容。结果410名受访者完成了调查问卷,关于难治性RA的特点:50%受访者认为基于28个关节评估的疾病活动评分(disease activity score assessing 28 joints,DAS28)>3.2或存在疾病活动的征象;42%受访者认为疲劳是其特点;48%认为至少两种传统合成改变病情抗风湿药(DMARDs)以及使用至少两种生物制剂或靶向合成DMARDs治疗失败;89%认为糖皮质激素不能减量到5 mg/天或泼尼松不能减量到10 mg/天或同等剂量的其他激素。另外,现有EULAR指南中应增加合并症和关节外表现的干预以及多种药物联合治疗等重要内容。结论目前风湿科医生对难治性RA的定义有很大争议。难治性RA患者的很多重要问题目前EULAR指南中均没有涉及。 | Nadia MT Roodenrijs Maria J H de Hair Marlies C van der Goes Johannes WG Jacobs Paco MJ Welsing Désirée van der Heijde Daniel Aletaha Maxime Dougados Kimme L Hyrich Iain B McInnes Ulf Mueller-Ladner Ladislav Senolt Zoltan Szekanecz Jacob Mvan Laar Nagy Gyorgy 黄艳荣(译) 张卓莉(审校) | 2019 | 英国医学杂志中文版2019，22，2： | 1 |
| 7 | Content and traffic of taurine in hippocampal reactive astrocytes显示文摘 | Junyent F De Lemos L Utrera J Paco S Aguado F Camins A Pallds M Romero R Auladell C | 2011 | Hippocampus2011，21，2： | 1 |
| 8 | Risk Factors for Preeclampsia:Results from a Cohort of Over 5000 Pregnancies in Spain显示文摘Objective:To determine the incidence of preeclampsia(PE)and preterm PE in Spain and to identify the risk factors for developing the disease.Methods:This is a multicenter prospective cohort study performed at six maternity units across Spain.Women with singleton pregnancies attending their first-trimester routine visit at the hospital were offered participation.Maternal and pregnancy characteristics,including mean arterial pressure,as well as ultrasound findings were recorded.Univariate and multivariate logistic regression analyses were performed to identify independent risk factors for subsequent development of PE.Results:A total of 5868 pregnancies were recruited for this study,including 174(3.0%)cases of PE,47(0.8%)cases of preterm PE and 127(2.2%)cases of term PE.Median maternal age was 33.9 years(interquartile range:30.1 to 36.9)and median gestational age at the routine visit was 12.7 weeks(interquartile range:12.3 to 13.0).However,293(5.0%)of the women were on aspirin treatment during pregnancy,likely reducing the true incidence of the disease.As expected,increasing body mass index(P<0.001),uterine artery pulsatility index(P=0.011)and mean arterial pressure(P<0.001),assisted conception(P=0.013),previous personal(P<0.001)or family history of PE(P=0.024)and chronic hypertension(P=0.001)were identified as independent risk factors for developing subsequent PE during pregnancy.Screening for PE by maternal factors alone leads to a detection rate of 36.8%(64/174)at 10.0%(587/5868)screen positive rate.Conclusion:In Spain,3.0%of singleton pregnancies are complicated by PE and 0.8%require delivery before term due to its severity.Screening of PE by risk factors alone is only able to detect about 40%of total PE at 10%screen-positive rate. | Diana Cuenca Valeria Rolle Katy de Paco Matallana Nuria Valiño Rocio Revello Begoña Adiego Manel Mendoza Belen Santacruz Maria del Mar Gil | 2021 | Maternal-Fetal Medicine2021，3，2： | 1 |
| 9 | Experiences with greening suppliers. The Universitat Autònoma de Barcelona显示文摘 | Alba Bala Paco Mu?oz Joan Rieradevall Pere Ysern | 2008 | Journal of Cleaner Production2008，，15： | 1 |
| 10 | Inducible nitric oxide synthase poly- morphism is associated with susceptibility to Henoch-Schonlein purpura in northwestern Spain显示文摘 | Martin J Paco L Ruiz MP | 2005 | J Rheaunato12005，32，6： | 1 |
| 11 | Oxidation of p -hydroxybenzoic acid by Fenton’s reagent显示文摘 | Francisco J. Rivas Fernando J. Beltrán Jesús Frades Paco Buxeda | 2000 | Water Research2000，，2： | 1 |
| 12 | Identification of a group B strepto-coccal fibronectin binding protein, SfbA, that contributes to inva- sion of brain endothelium and development of meningitis 显示文摘 | Mu R Kim B J Paco C | 2014 | In- fect Immun2014，82，6： | 1 |
| 13 | Umbilical cord blood acid-base and gas analysis after early versus delayed cord clam- ping in neonates at term显示文摘 | De Paco C Florido J Garrido M C | 2011 | Arch Gynecol Obstet2011，283，5： | 1 |
| 14 | Measurements and estimates of peach orchard, evapotranspiration in Mediterranean conditions显示文摘 | PACO T A FERREIRA M I CONCEICAO N | 2006 | Acta Horticulturae2006，664，： | 1 |
| 15 | Synthetic peptides representing the N-terminal segment of surfactant protein C modulate LPS-stimulated TNF-alpha production by macrophages显示文摘 | Garcia-Verdugo I Garcia de Paco E Espinassous Q | 2009 | Innate Immun2009，15，1： | 1 |
| 16 | Inducible nitric oxide synthase polymorphism is associated with susceptibility to Henoch-Sch(o)nlein purpura in northwestern Spain显示文摘 | Martin J Paco L Ruiz MP | 2005 | J Rheumatol2005，32，6： | 1 |
| 17 | Characterization of the W2C phase formed during the high ve- locity oxygen fuel spraying of a WC+ 12 pct Co powder显示文摘 | GUILEMANY J M DE PACO J M NUTTING J | 1999 | Metallurgical and Materials Transactions A1999，30，8： | 1 |
| 18 | Characterization of the W2C phase formed during the high Velocity oxygen fuel spraying of WC-12Co显示文摘 | Guilemany J M Paco J M Nutting J | 1999 | Metallurgical and Materials Transactions A1999，30，8： | 1 |
| 19 | Molecular evolution of the cadherin superfamily显示文摘 | Paco Hulpiau Frans van Roy | 2008 | International Journal of Biochemistry and Cell Biology2008，，： | 1 |
| 20 | Entrepreneuiship education: Relationship between education and entrepreneurial activity 显示文摘 | Mario Raposo Arminda do Paco | 2011 | Psicothema2011，23，3： | 1 |
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