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14篇 您的检索式:作者名="Paco C"
    题名 作者 年代 出处 被引量
1MHC classⅠmolecules act as tumor suppressor genes regulating the cell cycle gene expression,invasion and intrinsic tumorigenicity of melanoma cells显示文摘Garrido C Paco L Romero I 2012Carcinogenesis2012,33,3:1
2难治性类风湿关节炎的临床特点:一项国际问卷调查研究显示文摘目的尽管按照目前欧洲抗风湿联盟(EULAR)的推荐对类风湿关节炎(rheumatoid arthritis,RA)患者进行治疗,难治性RA患者的临床症状却仍然没有得到完全控制,目前EULAR指南主要关注的是RA的早期治疗和药物治疗。本研究的目的在于分析难治性RA患者的临床特点,以及在患者管理中需要探索然而现有EULAR指南并未涉及的问题。方法对多个国家的风湿科医生进行问卷调查,分析难治性RA的临床特点。问卷包括多选题以及开放性问题,从开放性问题的回答中发现需要进一步阐明的问题以及现有EULAR指南需要增加的内容。结果410名受访者完成了调查问卷,关于难治性RA的特点:50%受访者认为基于28个关节评估的疾病活动评分(disease activity score assessing 28 joints,DAS28)>3.2或存在疾病活动的征象;42%受访者认为疲劳是其特点;48%认为至少两种传统合成改变病情抗风湿药(DMARDs)以及使用至少两种生物制剂或靶向合成DMARDs治疗失败;89%认为糖皮质激素不能减量到5 mg/天或泼尼松不能减量到10 mg/天或同等剂量的其他激素。另外,现有EULAR指南中应增加合并症和关节外表现的干预以及多种药物联合治疗等重要内容。结论目前风湿科医生对难治性RA的定义有很大争议。难治性RA患者的很多重要问题目前EULAR指南中均没有涉及。Nadia MT Roodenrijs Maria J H de Hair Marlies C van der Goes Johannes WG Jacobs Paco MJ Welsing Désirée van der Heijde Daniel Aletaha Maxime Dougados Kimme L Hyrich Iain B McInnes Ulf Mueller-Ladner Ladislav Senolt Zoltan Szekanecz Jacob Mvan Laar Nagy Gyorgy 黄艳荣(译) 张卓莉(审校) 2019英国医学杂志中文版2019,22,2:1
3Content and traffic of taurine in hippocampal reactive astrocytes显示文摘Junyent F De Lemos L Utrera J Paco S Aguado F Camins A Pallds M Romero R Auladell C 2011Hippocampus2011,21,2:1
4Identification of a group B strepto-coccal fibronectin binding protein, SfbA, that contributes to inva- sion of brain endothelium and development of meningitis 显示文摘Mu R Kim B J Paco C 2014In- fect Immun2014,82,6:1
5Umbilical cord blood acid-base and gas analysis after early versus delayed cord clam- ping in neonates at term显示文摘De Paco C Florido J Garrido M C 2011Arch Gynecol Obstet2011,283,5:1
6Uterine and umbilical artery Doppler at 28 weeks for predicting adverse pregnancy outcomes in women with abnormal uterine artery Doppler findings in the early second trimester显示文摘Ventura W De Paco Matallana C Prieto-Sanchez MT 2015Prenat Diagn2015,35,3:1
7Transcriptomic profiling of TK2 deficient human skeletal muscle suggests a role for the p53 signalling pathway and identifies growth and differentiation factor-15 as a potential novel biomarker for mitochondrial my- opathies显示文摘KALKO SG PACO S JOU C 2014BMC Genomics2014,15,:1
8Umbilical cord blood acidbase and gas analysis after early versus delayed cord clamping in neonates at term显示文摘Paco C Florido J Garrido MC 2011Areh Gvneeol Obstet2011,283,:1
9Human leukocyte antigen-DQBl and -DRBI associations in patients with idiopathic sudden sensorineural hearing loss from a defined population of Northwest Spain显示文摘Amor-Dorado J C Paco L Martin J 2005Acta Otolaryngol2005,125,12:1
10Umbilical cord blood acid - base and gas analysis after early versus delayed cord dam- ping in neonates at term 显示文摘De Paco C Florido J Garrido MC 2011Arch Gynecol Obstet2011,283,5:1
11MHC class Ⅰ molecules act as tumor suppressor genes regulating the cell cycle gene expression,invasion and intrinsic tumorigenicity of melanoma cells显示文摘Garrido C Paco L Romero I 0,,:1
12Umbilical cord blood acid- base and gas analysis after early versus delayed cord clamping in neonates at term显示文摘De Paco C Florldo J Garrido MC 2011Arch Gynecol Obstet2011,283,5:1
13Effect of parity on maternal cardiac function during the first trimester of pregnancy显示文摘Turan OM De Paco C Kametas N 0,,07:1
14中国将怎样影响菲律宾印刷油墨业显示文摘过去几年间我频繁地前往中国旅行,映入眼帘的巨大变化时常令人难以言表。我所关注的焦点是中国工业的速度和规模,感觉似乎到处都在不停地进行着支撑工业的基础设施建设。然而我心中却浮起了一个念头……Bernardino C Paco 王以俊 2008印刷世界2008,13,4:0
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