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| 1 | Correlation between in vitro and in vivo immunomodulatory properties of lactic acid bacteria显示文摘AIM: To investigate the correlation between in vitro and in vivo immunomodulation potential of the probiotic strain and its ability to prevent experimental colitis in mice. METHODS: In vitro immunomodulation was assessed by measuring interleukin (IL)-12p70, IL-10, tumor necrosis factor alpha (TNFa) and interferon g (IFNg) release by human peripheral blood mononuclear cells (PBMCs) after 24 h stimulation with 13 live bacterial strains. A murine model of acute TNBS-colitis was next used to evaluate the prophylactic protective capacity of the same set of strains. RESULTS: A strain-specific in vivo protection was observed. The strains displaying an in vitro potential to induce higher levels of the anti-inflammatory cytokine IL-10 and lower levels of the inflammatory cytokine IL-12, offered the best protection in the in vivo colitis model. In contrast, strains leading to a low IL-10/IL-12 cytokine ratio could not significantly attenuate colitis symptoms. CONCLUSION: These results show that we could predict the in vivo protective capacity of the studied lactic acid bacteria (LAB) based on the cytokine profile we established in vitro. The PBMC-based assay we used may thus serve as a useful primary indicator to narrow down the number of candidate strains to be tested inmurine models for their anti-inflammatory potential. | Benoit Foligne Sophie Nutten Corinne Grangette Véronique Dennin Denise Goudercourt Sabine Poiret Joelle Dewulf Dominique Brassart Annick Mercenier Bruno Pot | 2007 | World Journal of Gastroenterology2007，13，2： | 22 |
| 2 | Protection against Yersinia pseudotuberculosis infection conferred by a Lactococcus lactis mucosal delivery vector secreting LcrV显示文摘 | Catherine Daniel Florent Sebbane Sabine Poiret Denise Goudercourt Joelle Dewulf Chantal Mullet Michel Simonet Bruno Pot | 2008 | Vaccine2008，，8： | 1 |
| 3 | Prevention and Treatment of Colitis With Lactococcus lactis Secreting the Immunomodulatory Yersinia LcrV Protein显示文摘 | Benoit Foligne Rodrigue Dessein Michael Marceau Sabine Poiret Mathias Chamaillard Bruno Pot Michel Simonet Catherine Daniel | 2007 | Gastroenterology2007，，3： | 1 |
| 4 | enod40,a gene expressed during nodule organogenesis,codes for a nontranslatable RNA involved in plant growth显示文摘 | CRESPI M JURKEVITCH E POIRET M | | 0，，： | 1 |
| 5 | Analysis of the resistome of a multidrug-resistant NDM-l-producing Escherichia coli strain by high-throughput genom sequencing 显示文摘 | Poiret L Bonnin RA Nordmann P | 2011 | Antimicrob Agents Che-mother2011，55，9： | 1 |
| 6 | Protection against Yersinia pseudotuberculosis infection conferred by a Lactococcus lactis mucosal delivery vector secreting LcrV显示文摘 | DANIEL C SEBBANE F POIRET S | 2009 | Vaccine2009，27，8： | 1 |
| 7 | 低铁玻璃的熔化及相应的耐火材料选择显示文摘太阳能面板和广泛应用于建筑及容器行业的超白玻璃需要高透过率的性能。这种性能主要取决于降低玻璃中的铁含量并将导致相对于普通钠钙玻璃熔化工艺的重大变革。因而用于熔化池的耐火材料必须谨慎选择,以便于提高玻璃质量及延长窑炉寿命。一些创新的耐火材料已经研发出来以满足这些特殊的需求,相对于普通的AZS砖材和次层铺底泥料,这些材料使用效果极佳。 | Jeremy Poiret Sebastion Bourdonnais 谭继民(译) | 2010 | 中国玻璃2010，，5： | 1 |
| 8 | Unexpected occurrence of plasmid-mediated quinolone resistance determinants in environmental Aeromonas spp 显示文摘 | Cattoir V Poiret L Aubert C | 2008 | Emergence Infect Disese2008，14，2： | 1 |
| 9 | T-Cell therapy: options for infectious diseases 显示文摘 | PARIDA S K POIRET T LIU Zhenjiang | 2015 | Clin Infect Dis2015，61，3： | 1 |
| 10 | Selecting lactic acid bacteria for their safety and functionality by use of a mouse colitis model显示文摘 | Daniel C Poiret S Goudercourt D | 2006 | Applied and Environmental Microbiology2006，72，9： | 1 |
| 11 | Selecting lactic acid bacteria for their safety and functionality by use of a mouse colitis model显示文摘 | Daniel C Poiret S Goudercourt D | | 0，，09： | 1 |
| 12 | Characterization of VIM-2, a carbapenem-hydrolyzing metallo-beta-lactamase and its plasmid and integron-borne gene from a Pseudomonas aeruginosa clinical isolate in France显示文摘 | Poiret L Naas T Nicolas D | 2000 | Antimicrob Agents Chemother2000，44，4： | 1 |
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