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    题名 作者 年代 出处 被引量
1Phase II trial of Sorafenib in conjunction with chemotherapy and as maintenance therapy in extensive-stage small cell lung cancer显示文摘Neelesh Sharma Nathan Pennell Myles Nickolich Balazs Halmos Patrick Ma Tarek Mekhail Pingfu Fu Afshin Dowlati 2014Investigational New Drugs2014,,2:2
2Cross‐talk between MAP kinase pathways is involved in IGF‐independent, IGFBP‐6‐induced Rh30 rhabdomyosarcoma cell migration显示文摘PingFu Guang JunLiang Sahil S.Khot RobertPhan Leon A.Bach 2010J Cell Physiol2010,,3:1
3Combined SCLC Clinical and Pathologic Characteristics 显示文摘Shahab B Pingfu F Michael Y 2013Clinical Lung Cancer2013,14,2:1
4Apigenin attenuates insulin-like growth factor-1 signaling in an autochthonous nouse prostate cancer model显示文摘Shukla S MacLennan G T Fu Pingfu 0,,:1
5Risk factors for the prognosis of acute kidney injury under the Acute Kidney Injury Network definition: A retrospective, multicenter study in critically ill patients显示文摘JIAOJIAOZHOU LICHUANYANG KANGYIZHANG YUNLIU PINGFU 2012Nephrology2012,,4:1
6Deregulation of FOXO3A during prostate cancer progression显示文摘Sanjeev Shukla Meenakshi Shukla Gregory MacLennan Pingfu Fu Sanjay Gupta 2009International Journal of Oncology2009,,6:1
7Determinants of delegation and consultation by managers显示文摘GaryYukl Ping PingFu 1999J Organiz Behav1999,,2:1
8MUC1 is expressed at high frequency in early-stage basal-like triple-negative breast cancer显示文摘Alan Siroy Fadi W. Abdul-Karim John Miedler Nancy Fong Pingfu Fu Hannah Gilmore Joseph Baar 2013Human Pathology2013,,:1
9Earliest Modern Humans in Southern China Recast History of Early Human Migration显示文摘The hominin record from southern Asia for the early Late Pleistocene epoch is scarce.Well-dated and well-preserved fossils older than 45.000 years that can be unequivocally attributed to H.sapiens are lacking.In a paper published October 15 online in Nature,Dr.LIU Wu from Institute of Vertebrate Paleontology and Paleoanthropology(IVPP).CAS,and his international team announced the discovery of human teeth between 80.000 and120,000 years old from the newly excavated Fuyan Cave in Daoxian.southern China,and provided the earliestCHEN Pingfu 2015Bulletin of the Chinese Academy of Sciences2015,29,4:0
10New Oligocene Primates from China Highlight Ancient Climate Change as Possible Evolution Filter显示文摘Profound environmental and faunal changes are associated with climatic deterioration during the Eocene-Oligocene transition(EOT)roughly 34 million years ago.Primates are among the most environmentally sensitive of all mammals.Reconstructing how Asian primates responded to the EOT,however,has been hindered by a sparse record of Oligocene primates on that continent.chen pingfu 2016Bulletin of the Chinese Academy of Sciences2016,30,2:0
11CAS Paleontologist Named L'Oréal-UNESCO Outstanding Women in Science显示文摘Paleontologist Dr.CHANG Meemann(ZHANG Miman),CAS Member and senior professor of the Institute of Vertebrate Paleontology and Paleoanthropology(IVPP),Chinese Academy of Sciences,was selected on November 13,2017 by UNESCO and the L’Oréal Foundation as one of the five outstanding female scientists from around the world for'her pioneering work on fossil records leading to insights on how aquatic vertebrates adapted to life on land.'Dr.CHANG and other four women scientists,Profs.Heather Zar,Janet Rossant,Caroline DeanCHEN Pingfu 2017Bulletin of the Chinese Academy of Sciences2017,31,4:0
12Exceptionally Preserved Eggs and Embryos Reveal the Life History of a Pterosaur显示文摘Pterosaur eggs and embryos well preserved with 3-D details help unveil life episodes of this winged dinosaur.CHEN Pingfu 2017Bulletin of the Chinese Academy of Sciences2017,31,4:0
13New Finds in China Suggesting Different Story of Human Evolutionary History显示文摘Updated fossil evidence from Asia and more accurate analysis with aid from state-of-theart methods are showing that a dazzling variety of Homo species once roamed the continent,posing challenges to conventional ideas about the evolutionary history of humanity.'But it’s increasingly clear that many Asian materials cannot fit into the traditional narrative of human evolution,'said WU Xinzhi,a senior professor of the Institute of Vertebrate PaleontologyCHEN Pingfu 2016Bulletin of the Chinese Academy of Sciences2016,30,3:0
14Pathological images for personal medicine in Hepatocellular carcinoma:Cross-talk of gene sequencing and pathological images显示文摘Background:Considering the great heterogeneity of Hepatocellular carcinoma(HCC),more accurate prognostic models are urgently needed.This paper combined the advantages of genomics and pathomics to construct a prognostic model.Methods:First,we collected data from hepatocellular carcinoma patients with complete mRNA expression profiles and clinical annotations from the TCGA database.Then,based on immune-related genes,we used random forest plots to screen prognosis-related genes and build prognostic models.Bioinformatics was used to identify biological pathways,evaluate the tumor microenvironment,and perform drug susceptibility testing.Finally,we divided the patients into different subgroups according to the gene model algorithm.Pathological models were constructed by obtaining HE-stained sections from TCGA in corresponding subgroups of patients.Results:In this study,we constructed a stable prognostic model that could predict overall survival in HCC patients.The signature consisted of six immune-related genes(BX537318.1,TMEM147,CSPG4P12,AC015908.3,CEBPZOS,and SRD5A3).We found increased levels of infiltration of immune cells in the tumor microenvironment in patients with low risk scores,indicating significant antitumor immunity and corresponding to better clinical outcomes.We then screened nine drugs that were more sensitive in the low-risk group than in the high-risk group.Finally,we addressed the complex cellular changes and phenotypic heterogeneity in the HCC microenvironment by combining genomics and pathomics analysis methods.Conclusion:Our study showed that the prognostic evaluation model of HCC based on the immune signaling pathway is feasible and provided a reference value for potential immunotherapy for HCC.LI YANG KUN DENG ZHIQIANG MOU PINGFU XIONG JIAN WEN JING LI 2022Oncology Research2022,30,5:0
15CAS Paleontologist Presented with L'Oréal-UNESCO Award for Women in Science显示文摘Since Charles Robert Darwin’s time,scientists had long thought that terrestrial vertebrates,including humankind itself,had evolved from an intermediate species called lungfish,given that this special species could breathe with either gills or lungs,and this amphibian ability could have offered it advantages over others when adapting to life on land.The framework for exploring the phylogenetic relationships of sarcopterygians and the originCHEN Pingfu SONG Jianlan 2018Bulletin of the Chinese Academy of Sciences2018,32,1:0
16Development of RT PCR Assay for Detection of Duck Hepatitis Virus Type 1显示文摘In this study,a RT-PCR assay for rapid detection of duck hepatitis virus type 1( DHV-1) was established in the presence of a pair of primers designed based on vp1 gene sequence,using the genomic RNA of DHV-1 or other common viruses as the template. The template was serially diluted 10-fold to determine the reaction sensitivity. Finally,seven liver samples of ducks with suspected DHV-1 infection,which were collected from different regions of Jiangsu Province,were detected with this method. The results showed that a DNA fragment of about 360 bp was specifically amplified with the RT-PCR system,and the detection limit was1 fg/μL. The detection rate of clinical samples with this method was 100%. The results revealed that the RT-PCR system which had high specificity and high sensitivity in the detection of DHV-1 was successfully established.Wang Yongjuan Cui Pingfu Liu Bo Meng Ting 2017Animal Husbandry and Feed Science2017,9,5:0
17Survival in men older than 75 years with low- and intermediate-grade prostate cancer managed with watchful waiting with active surveillance显示文摘Objective:Recent studies have reported the underuse of active surveillance or watchful wait-ing for low-risk prostate cancer in the United States.This study examined prostate cancer-specific and all-cause death in elderly patients older than 75 years with low-risk tumors managed with active treatment versus watchful waiting with active surveillance(WWAS).Methods:We performed survival analysis in a cohort of 18,599 men with low-risk tumors(early and localized tumors)who were 75 years or older at the time of prostate cancer diagnosis in the linked Surveillance,Epidemiology,and End Results(SEER)-Medicare database(from 1992 to 1998)and who were followed up through December 2003.WWAS was defined as having an-nual screening for prostate-specific antigen and/or digital rectal examination during the follow-up period.The risks of prostate cancer-specific and all-cause death were compared by Cox regression models.The propensity score matching technique was used to address potential selection bias.Results:In patients with well-differentiated(Gleason score 2-4)and localized disease,those managed with WWAS without delayed treatment had higher risk of all-cause death(hazard ratio 1.20,95%confidence interval 1.13-1.28)but a substantially lower risk of prostate cancer-specific death(hazard ratio 0.62,confidence interval 0.51-0.75)than patients undergoing active treatment.Patients managed with WWAS with delayed treatment had comparable mortality outcomes.Sensi-tivity analyses based on propensity score matching yielded similar results.Conclusion:In men older than 75 years with well-differentiated and localized prostate cancer,WWAS without delayed treatment had a lower risk of prostate cancer-specific death and compa-rable all-cause death as compared with active treatment.Those patients in whom treatment was delayed had comparable mortality outcomes.Our results support WWAS as an initial management option for older men with well-differentiated and localized prostate cancer.Tzuyung D.Kou Siran M.Koroukian Pingfu Fu Derek Raghavan Gregory S.Cooper Li Li 2015Family Medicine and Community Health2015,3,3:0
18Institute of Vertebrate Paleontology and Paleoanthropology:revealing the origin and evolutionary trace of human and other species显示文摘INTRODUCTION The Institute of Vertebrate Paleontology and Paleoanthropology(IVPP),Chinese Academy of Sciences(CAS),is China's only national institute specializing in the studies of vertebrate paleontology,paleoanthropology,and the related areas of geological and biological sciences as well as paleolithic archaeology.The origin of IVPP can be traced back to the Ce no zoic Research Laboratory,Xiuling Xu Pingfu Chen 2018National Science Review2018,5,1:0
19Origin of Birds: Decade-Long Efforts and Evidence from China显示文摘In its 2014 version of top 10 ground-breaking discoveries and achievements released on December 19,Science,the world-leading journal included the transition from dinosaurs to birds in its annual selection,noting that a series of papers detailed how certain dinosaurian lineages developed small,lightweight body features,which have enabled them to evolve into birds and gain the ability to fly.The dinosaur-bird transition,now evaluated as oneCHEN Pingfu ZHAO Guoxing PENG Guoqing 2015Bulletin of the Chinese Academy of Sciences2015,29,1:0
20From Dinosaurs to Birds:Puzzles Unraveled while Evidence Building up显示文摘Rejuvenation of dinosaurian origin of birds and its theoretical difficultiesIn 1986, Prof. Jacques Gauthier from Yale University first applied cladistic systimatics to the analysis ofCHEN Pingfu SONG Jianlan 2010Bulletin of the Chinese Academy of Sciences2010,24,2:0
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