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5篇 您的检索式:作者名="Pingfu Fu"
    题名 作者 年代 出处 被引量
1Phase II trial of Sorafenib in conjunction with chemotherapy and as maintenance therapy in extensive-stage small cell lung cancer显示文摘Neelesh Sharma Nathan Pennell Myles Nickolich Balazs Halmos Patrick Ma Tarek Mekhail Pingfu Fu Afshin Dowlati 2014Investigational New Drugs2014,,2:2
2Apigenin attenuates insulin-like growth factor-1 signaling in an autochthonous nouse prostate cancer model显示文摘Shukla S MacLennan G T Fu Pingfu 0,,:1
3Deregulation of FOXO3A during prostate cancer progression显示文摘Sanjeev Shukla Meenakshi Shukla Gregory MacLennan Pingfu Fu Sanjay Gupta 2009International Journal of Oncology2009,,6:1
4MUC1 is expressed at high frequency in early-stage basal-like triple-negative breast cancer显示文摘Alan Siroy Fadi W. Abdul-Karim John Miedler Nancy Fong Pingfu Fu Hannah Gilmore Joseph Baar 2013Human Pathology2013,,:1
5Survival in men older than 75 years with low- and intermediate-grade prostate cancer managed with watchful waiting with active surveillance显示文摘Objective:Recent studies have reported the underuse of active surveillance or watchful wait-ing for low-risk prostate cancer in the United States.This study examined prostate cancer-specific and all-cause death in elderly patients older than 75 years with low-risk tumors managed with active treatment versus watchful waiting with active surveillance(WWAS).Methods:We performed survival analysis in a cohort of 18,599 men with low-risk tumors(early and localized tumors)who were 75 years or older at the time of prostate cancer diagnosis in the linked Surveillance,Epidemiology,and End Results(SEER)-Medicare database(from 1992 to 1998)and who were followed up through December 2003.WWAS was defined as having an-nual screening for prostate-specific antigen and/or digital rectal examination during the follow-up period.The risks of prostate cancer-specific and all-cause death were compared by Cox regression models.The propensity score matching technique was used to address potential selection bias.Results:In patients with well-differentiated(Gleason score 2-4)and localized disease,those managed with WWAS without delayed treatment had higher risk of all-cause death(hazard ratio 1.20,95%confidence interval 1.13-1.28)but a substantially lower risk of prostate cancer-specific death(hazard ratio 0.62,confidence interval 0.51-0.75)than patients undergoing active treatment.Patients managed with WWAS with delayed treatment had comparable mortality outcomes.Sensi-tivity analyses based on propensity score matching yielded similar results.Conclusion:In men older than 75 years with well-differentiated and localized prostate cancer,WWAS without delayed treatment had a lower risk of prostate cancer-specific death and compa-rable all-cause death as compared with active treatment.Those patients in whom treatment was delayed had comparable mortality outcomes.Our results support WWAS as an initial management option for older men with well-differentiated and localized prostate cancer.Tzuyung D.Kou Siran M.Koroukian Pingfu Fu Derek Raghavan Gregory S.Cooper Li Li 2015Family Medicine and Community Health2015,3,3:0
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