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| 1 | Phytochemical and anti-bacterial activity of epidermal glands extract of Christella parasitica (L.) H. Lev.显示文摘Objective:To study the morphology,biochemistry and bioactivity of the epidermal glands of the glandular morphotype of Christella parasitica(C.parasitica)(L.) H.Lev.Methods: Morphological studies on epidermal glands were earned out by using light microscope and scanning electron microscope.To prepare the extract,the shade-dried fronds of glandular morphotype were soaked in acetone.For antibacterial studies paper disc method was followed by using various pathogenic bacteria.Results:Detailed micromorphological,phytochemical and bioactivity studies on a medicinal fern C.parasitica(L.) H.Lev.showed its inlraspecific variation in antibacterial activity.The presence or absence of the epidermal glands was the key factor for antibacterial activity in the morphovariants of this species.The epidermal glands were orange-coloured,stalked and elongated ones of about 84.2μm×45μm,and distributed on the undersurface of cosla,coslules and veins in croziers,young and mature leaves.Frequency of glands varied from 15/cm on costa in mature leaves to 140/cm on costules in croziers.The acetone extract of the glands showed antibacterial activities and also toxic effect against mosquito larvae and tadpoles of frog.Preliminary phytochemical analysis and HPLC studies of the gland extract showed the presence of various kinds of terpenoids,alkaloids,tannins,saponins and flavonoids in it.Conclusions:The present study shows that epidermal glands of the glandular morphotype of C. parasitica(L.) H.Lev.have several bioactive compounds and such rare moiphovariant should be conserved in nature.The next step is to isolate the pure compounds and to screen the bioactivity of individual compounds of the epidermal glands. | Paul Raj K Irudayaraj V Johnson M Patric Raja D | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，1： | 14 |
| 2 | Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling:Influence of smoking显示文摘瞄准:为了调查一个模糊逻辑模型是否能预言肤色,表面的癌症(CRC ) 风险由在世袭 non-polyposis 肤色吸表面的癌症(HNPCC ) 病人产生了。方法:从 Creighton 大学世袭癌症研究所登记的 340 个 HNPCC 失配修理(MMR ) 变化搬运人为当模特儿被选择。年龄依赖者曲线被产生阐明开发 CRC 的概率上的在基因变化(hMLH1 或 hMSH2 ) 之间的联合效果,性,和吸烟地位。结果:在男 hMSH2 变化搬运人的吸烟显著地增加的 CRC 风险(P <
0.05 ) 。hMLH1 变化为男性相对 hMSH2 变化搬运人扩充了 CRC 风险(P <
0.05 ) 。男性们非为 hMLH1 比女性有 CRC 的显著地更高的风险吸烟者(P <
0.05 ) , hMLH1 吸烟者(P <
0.1 ) 并且 hMSH2 吸烟者(P <
0.1 ) 。以在在男性的 hMSH2 的一种剂量依赖者方式的吸烟支持的 CRC (P <
0.05 ) 。有 hMSH2 变化的女性和与 hMLH1 组一起的两性仅仅在广泛的吸烟历史以后表明了吸烟效果(P <
0.05 ) 。结论:由在 HNPCC 病人吸烟的 CRC 提升依赖于基因变化,性和年龄。这些数据证明模糊建模可以启用临床的风险分数的明确的表达,从而允许 CRC 预防策略的 individualization。 | Rhonda M Brand David D Jones Henry T Lynch Randall E Brand Patrice Watson Ramesh Ashwathnayaran Hemant K Roy | 2006 | World Journal of Gastroenterology2006，12，28： | 5 |
| 3 | Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study显示文摘AIM: To determine the presence of Helicobacter species DNA in the liver of chronic hepatitis C (CHC) patients with and without cirrhosis as compared to controls, and to identify the bacterial species involved. METHODS: Seventy-nine consecutive patients (HBV and HIV negative) with a liver sample obtained after liver biopsy or hepatic resection were studied: 41 with CHC without cirrhosis, 12 with CHC and cirrhosis, and 26 controls (HCV negative). Polymerase chain reactions (PCRs) targeting Helicobacter 16S rDNA and species- specific were performed on DNA extracted from the liver. A gastric infection with H pylori was determined by serology and confirmed by 13C-urea breath test. RESULTS: Overall, Helicobacter 16S rDNA was found in 16 patients (20.2%). Although positive cases tended to be higher in CHC patients with cirrhosis (41.6%) than in those without cirrhosis (17.0%) or in controls (15.4%), the difference was not statistically significant (P =0.08). H pylori-like DNA was identified in 12 cases and H. pullorum DNA in 2, while 2 cases remained unidenti- fied. Gastric infection with H pylori was found in only 2 of these patients. CONCLUSION: Our results do not confirm the associ- ation of Helicobacter species DNA in the liver of CHC patients with advanced liver disease. The lack of correlation between positive H pylori serology and the presence of H pylori-like DNA in the liver may indicate the presence of a variant of this species. | Laurent Castéra Anne Pedeboscq Marcia Rocha Brigitte Le Bail Corinne Asencio Victor de Lédinghen Pierre-Henri Bernard Christophe Laurent Marie-Edith Lafon Maylis Capdepont Patrice Couzigou Paulette Bioulac-Sage Charles Balabaud FrancisMégraud Armelle Ménard | 2006 | World Journal of Gastroenterology2006，12，45： | 3 |
| 4 | Measurement of bound states in the continuum by a detector embedded in a photonic crystal显示文摘We directly measure optical bound states in the continuum(BICs)by embedding a photodetector into a photonic crystal slab.The BICs observed in our experiment are the result of accidental phase matching between incident,reflected and in-plane waves at seemingly random wave vectors in the photonic band structure.Our measurements were confirmed through a rigorously coupled-wave analysis simulation in conjunction with temporal coupled mode theory.Polarization mixing between photonic crystal slab modes was observed and described using a plane wave expansion simulation.The ability to probe the field intensity inside the photonic crystal and thereby to directly measure BICs represents a milestone in the development of integrated opto-electronic devices based on BICs. | Roman Gansch Stefan Kalchmair Patrice Genevet Tobias Zederbauer Hermann Detz Aaron M Andrews Werner Schrenk Federico Capasso Marko Lončar Gottfried Strasser | 2016 | Light(Science & Applications)2016，5，1： | 2 |
| 5 | Gut microflora as a target for energy and metabolic homeostasis显示文摘 | Patrice D Cani Nathalie M Delzenne | 2007 | Current Opinion in Clinical Nutrition and Metabolic Care2007，，6： | 2 |
| 6 | Spatial bandwidth extended reconstruction for digital color Fresnel holograms显示文摘 | PASCAL P PATRICE T DENIS M | | 0，，11： | 1 |
| 7 | Growth regulators have rapid effects on photosynthetic unloading from seed coats of Phaseolus vulgaris L显示文摘 | CLIFFORD P E OFFLER C E PATRIC J M | 1986 | Plant Physiology1986，80，： | 1 |
| 8 | Weak sharp solutions of variational inequalities显示文摘 | PATRICE M DAO L ZH | | 0，，09： | 1 |
| 9 | Chorioamnionitis increases neonatalmorbidity in pregancies complicated by pretem premature ruptureof mombranes显示文摘 | Patric S RamseyPS Joelle M | 2005 | Am J Obstet Gynecol2005，192，4： | 1 |
| 10 | etsl -casein is required for the effi- cient transport of I- and K-casein from the endoplasmic reticulum to the Golgi apparatus of mammary epithelial cells 显示文摘 | Eric C Patrice M Michele O B | 1999 | Journal of Cell Science1999，112，： | 1 |
| 11 | Promising designs of compact heat exchangers for modular HTRs using the Brayton cycle显示文摘 | Franck P Patrice T Christian M | 2008 | Nuclear Engineering and Design2008，238，11： | 1 |
| 12 | Microinjection molding of thermoplastic polymers: morphological comparison with conventional injection molding 显示文摘 | JULIEN G THIERRY C PATRICE M | 2009 | Journal of Micromechanics and Microengineering2009，19，02： | 1 |
| 13 | A unified artificial neural network architecture for active power filters显示文摘 | Djaffar O A Patrice W Jean M | 2007 | IEEE Trans on Industrial Electronics2007，54，1： | 1 |
| 14 | Occupational slips and falls:more than a trivial problem显示文摘 | Leamon T B Patrice L M | 1995 | Ergonomics1995，38，3： | 1 |
| 15 | Chitosan as absorption enhancers of poorly absorbable drugs 3:Influence of mucus on absorption enhancement显示文摘 | Nicolaas G M Kjell M Schipper Stenberg Patric | 1999 | European Journal of Pharmaceutical Sciences1999，8，： | 1 |
| 16 | Patient satisfaction after MRCP and ERCP显示文摘 | Krishna Menon Alan N Barkun Joseph Romagnuolo Gad Friedman Shailesh N Mehta Caroline Reinhold Patrice M Bret | 2001 | The American Journal of Gastroenterology2001，，9： | 1 |
| 17 | Electro-optical characterization of tektronix TK512M-011 charge-coupled devices 显示文摘 | Patric M Epperson | 1987 | Opt Engng1987，26，8： | 1 |
| 18 | Hepatic intraaterial iodized oil for treatment of hepatocellular carcinoma in patients with impeded portal venous flow 显示文摘 | Thierry B Patrice TI Jean M | 1999 | Radiology1999，212，3： | 1 |
| 19 | Structural characterization of bis(L-Met) 显示文摘 | Roxy B W Patrice de M Derek J H | 1977 | Inorg Chem1977，16，6： | 1 |
| 20 | The Other CSR 显示文摘 | Timothy M Devinney Patrice Auger Giana Eckhardt Thomas Birtchnell | 2006 | Stanford Social Innovation Review2006，4，3： | 1 |
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