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| 1 | A comparative study of hemodynamic responses to orotracheal intubation with fiberoptic bronchoscope and laryngoscope in children显示文摘 | F.S.XUE G.H.ZHANG H.T.SUN C.W.LI P.LI K.P.LIU Y.C.XU Y.LIU J.LIU | 2006 | Pediatric Anesthesia2006,,7: | 1 |
| 2 | Smoking and depressive symptoms in Chinese elderly in Hong Kong显示文摘 | T. H.Lam Z. B.Li S. Y.Ho W. M.Chan K. S.Ho M. P.Li G. M.Leung | 2004 | Acta Psychiatrica Scandinavica2004,,3: | 1 |
| 3 | COX‐2 mRNA expression in esophageal squamous cell carcinoma (ESCC) and effect by NSAID显示文摘 | X.Liu P.Li S.‐T.Zhang H.You J.‐D.Jia Z.‐L.Yu | 2007 | Diseases of the Esophagus2007,,1: | 1 |
| 4 | Color Doppler twinkling artifact in fetuses with echogenic intracardiac foci: echocardiographic observation and clinical significance显示文摘 | B. W.Zhao Y.Yang M.Pan P.Li B.Wang F. G.Tang | 2010 | Ultrasound Obstet Gynecol2010,,5: | 1 |
| 5 | Existence and global attractivity of positive periodic solutions for a Holling Ⅱ two-prey one-predator system显示文摘 | Ch.Xu P.Li Y.Shao | | 0,,84: | 1 |
| 6 | Nuclear factor‐κB/p65 responds to changes in the Notch signaling pathway in murine BV‐2 cells and in amoeboid microglia in postnatal rats treated with the γ‐secretase complex blocker DAPT显示文摘 | Q.Cao P.Li J.Lu S.T.Dheen C.Kaur E.‐A.Ling | 2010 | J Neurosci Res2010,,12: | 1 |
| 7 | 查看详情显示文摘 | Li J. Z Wei Y. X Liu G. Y Qi Y.Tian P.Li B.He Y.L.Liu Z.M | | 0,,01: | 1 |
| 8 | Real Estate and Economies of Scale:The Case of REITs显示文摘 | Ambrose B Highfield M P.Li an | | 0,,02: | 1 |
| 9 | Novel mutation breeding method for Streptomyces avermitilis using an atmospheric pressure glow discharge plasma显示文摘 | L.‐Y.Wang Z.‐L.Huang G.Li H.‐X.Zhao X.‐H.Xing W.‐T.Sun H.‐P.Li Z.‐X.Gou C.‐Y.Bao | 2010 | Journal of Applied Microbiology2010,,3: | 1 |
| 10 | Clinical trial: the efficacy and tolerability of velusetrag, a selective 5‐HT<sub>4</sub> agonist with high intrinsic activity, in chronic idiopathic constipation – a 4‐week, randomized, double‐blind, placebo‐controlled, dose–response study显示文摘 | M.Goldberg Y.‐P.Li J. F.Johanson A. W.Mangel M.Kitt D. T.Beattie K.Kersey O.Daniels | 2010 | Alimentary Pharmacology & Therapeutics2010,,9: | 1 |
| 11 | 查看详情显示文摘 | P.Li X.Duan Z.Chen | | 0,,: | 1 |
| 12 | 查看详情显示文摘 | P.Li P.Y.Cui H.T.Cui | | 0,,: | 1 |
| 13 | Thermally processed sewage sludge for methylene blue uptake显示文摘 | H.Djati Utomo X C.Ong S.M.S.Lim G.C.B.Ong P.Li | | 0,,: | 1 |
| 14 | 查看详情显示文摘 | P.B.He Q.Sun P.Li S.Q.Shen and W.M.Liu | | 0,,04: | 1 |
| 15 | Composition of amino acids in feed ingredients for animal diets显示文摘 | Li X R.Rezaei P.Li | | 0,,04: | 1 |
| 16 | U–Pb zircon geochronology of coesite‐bearing eclogites from the southern Dulan area of the North Qaidam UHP terrane, northwestern China: spatially and temporally extensive UHP metamorphism during continental subduction显示文摘 | J. X.ZHANG C. G.MATTINSON S. Y.YU J. P.LI F. C.MENG | 2010 | Journal of Metamorphic Geology2010,,9: | 1 |
| 17 | Copy number variations of the human histamine H4 receptor gene are associated with systemic lupus erythematosus显示文摘 | B.Yu Y.Shao P.Li J.Zhang Q.Zhong H.Yang X.Hu B.Chen X.Peng Q.Wu Y.Chen M.Guan J.Wan W.Zhang | 2010 | British Journal of Dermatology2010,,5: | 1 |
| 18 | Skeletal muscle fiber-type switching,exercise intolerance,and myopathy in PGC-1alpha muscle-specific knock-out animals显示文摘 | C.Handschin S.Chin P.Li F.Liu E.Maratos-Flier N.K.Lebrasseur Z.Yan B.M.Spiegelman | | 0,,: | 1 |
| 19 | Combining cisplatin and a STING agonist into one molecule for metalloimmunotherapy of cancer显示文摘Mounting evidence suggests that strategies combining DNA-damaging agents and stimulator of interferon genes(STING) agonists are promising cancer therapeutic regimens because they can amplify STING activation and remodel the immunosuppressive tumor microenvironment. However, a single molecular entity comprising both agents has not yet been developed. Herein, we designed two PtIV-MSA-2 conjugates(Ⅰand Ⅱ) containing the DNA-damaging chemotherapeutic drug cisplatin and the innate immuneactivating STING agonist MSA-2;these conjugates showed great potential as multispecific small-molecule drugs against pancreatic cancer. Mechanistic studies revealed that conjugate Ⅰ upregulated the expression of transcripts associated with innate immunity and metabolism in cancer cells, significantly differing from cisplatin and MSA-2. An analysis of the tumor microenvironment demonstrated that conjugate I could enhance the infiltration of natural killer(NK) cells into tumors and promote the activation of T cells, NK cells and dendritic cells in tumor tissues. These findings indicated that conjugate I, which was created by incorporating a Pt chemotherapeutic drug and STING agonist into one molecule, is a promising and potent anticancer drug candidate, opening new avenues for small-molecule-based cancer metalloimmunotherapy. | Shuren Zhang Dongfan Song Wenhao Yu Ji Li Xiaoyu Wang Yachao Li Zihan Zhao Qi Xue Jing Zhao Jie P.Li Zijian Guo | 2024 | National Science Review2024,11,1: | 0 |
| 20 | Depolarization of intense laser beams by dynamic plasma density gratings显示文摘As a typical plasma-based optical element that can sustain ultra-high light intensity,plasma density gratings driven by intense laser pulses have been extensively studied for wide applications.Here,we show that the plasma density grating driven by two intersecting driver laser pulses is not only nonuniform in space but also varies over time.Consequently,the probe laser pulse that passes through such a dynamic plasma density grating will be depolarized,that is,its polarization becomes spatially and temporally variable.More importantly,the laser depolarization may spontaneously take place for crossed laser beams if their polarization angles are arranged properly.The laser depolarization by a dynamic plasma density grating may find application in mitigating parametric instabilities in laser-driven inertial confinement fusion. | Y.X.Wang S.M.Weng P.Li Z.C.Shen X.Y.Jiang J.Huang X.L.Zhu H.H.Ma X.B.Zhang X.F.Li Z.M.Sheng J.Zhang | 2023 | High Power Laser Science and Engineering2023,11,3: | 0 |