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| 1 | 软土地面中机械化双叠隧道的三维数值模拟(英文)显示文摘研究目的:通过三维数值模拟,研究隧道施工过程对双叠隧道的影响。创新要点:使用全三维数值模拟方法研究软土中双叠隧道施工对先挖隧道或地面的影响。研究方法:1.运用FLAC软件创建双叠隧道的三维数值模型(图1);2.分情况模拟机械化双叠隧道的挖掘过程;3.研究不同情况下的地面沉降,水平地面位移,以及隧道衬砌的法向位移、法向力、纵向力和弯曲力矩等。重要结论:1.新隧道施工对现有的隧道有很大的影响,最大影响出现在先挖上层隧道的情况下;2.一般来说,上层隧道的挖掘会比下层隧道产生更大的地面沉降;3.下层隧道产生的法向力总是比上层隧道大;4.在多数情况下,下层隧道产生的法向位移和弯曲力矩要比上层隧道小。 | Ngoc-Anh DO Daniel DIAS Pierpaolo ORESTE | 2014 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2014，15，11： | 12 |
| 2 | Analysis of predictor equations for determining the blast-induced vibration in rock blasting显示文摘The paper proposes a new empirical correlation designed to complement the‘‘site laws'currently used to evaluate the attenuation in the rock masses of vibrations induced by rock blasting.The formula contains a deformed exponential known as the K-exponential,which seems to well represent a large number of both natural and artificial phenomena ranging from astrophysics to quantum mechanics,with some extension in the field of economics and finance.Experimental validation of the formula was performed via the analysis of vibration data covering a number of case studies,which differed in terms of both operation and rock type.A total of 12 experimental cases were analysed and the proposed formulation exhibited a good performance in 11 of them.In particular,the proposed law,which was built using blast test data,produced very good approximations of the points representing the vibration measurements and would thus be useful in organising production blasts.However,the developed formula was found to work less well when a correlation obtained for a given site was applied to another presenting similar types of rocks and operations,and thus should not be employed in the absence of measurements from test data. | Marilena Cardu Dario Coragliotto Pierpaolo Oreste | 2019 | International Journal of Mining Science and Technology2019，29，6： | 4 |
| 3 | Laboratory tests to study the influence of rock stress confinement on the performances of TBM discs in tunnels显示文摘To clarify some aspects of rock destruction with a disc acting on a high confined tunnel face, a series of tests were carried out to examine fracture mechanisms under an indenter that simulates the tunnel boring machine (TBM) tool action, in the presence of an adjacent groove, when a state of stress (lateral confinement) is imposed on a rock sample. These tests proved the importance of carefully establishing the optimal distance of grooves produced by discs acting on a confined surface, and the value (as a mere order of magnitude) of the increase of the thrust to produce the initiation of chip formation, as long as the confinement pressure becomes greater. | N. Innaurato C. Oggeri P. Oreste R. Vinai | 2011 | International Journal of Minerals,Metallurgy and Materials2011，18，3： | 4 |
| 4 | Experimental and Numerical Studies on Rock Breaking with TBM Tools under High Stress Confinement显示文摘 | N. Innaurato C. Oggeri P. P. Oreste R. Vinai | 2007 | Rock Mechanics and Rock Engineering2007，，5： | 3 |
| 5 | The effect of cooling rates on the microstructure and mechanical properties of thermo-mechanically processed Ti–Al–Mo–V–Cr–Fe alloys显示文摘 | Mansur Ahmed Dmytro G. Savvakin Orest M. Ivasishin Elena V. Pereloma | 2013 | Materials Science & Engineering A2013，，： | 3 |
| 6 | Decrease of serum carnitine levels in patients with or without gastrointestinal cancer cachexia显示文摘瞄准:在消化机关与癌症在病人评估浆液肉毒碱的层次并且把他们与另外的癌症作比较以便提供新卓见进极度瘦弱的机制。方法:55 个恶病质病人与或没有胃肠的癌症在现在的学习被注册。他们经历了平淡的实验室调查,包括在浆液在场的肉毒碱的各种各样的形式的层次的检查(即,长链的酰肉毒碱,短链的酰肉毒碱,免费肉毒碱,和全部的肉毒碱) 。这些价值与 30 个健康控制题目在好营养的地位以及与那些在 60 个癌症病人发现的那些相比。结果:当没有胃肠的癌症,有胃肠的癌症的恶病质病人与恶病质病人相比时,差别是在免费肉毒碱的 -6.8 micromol/L (P <
0.005 ) ,在长链酰肉毒碱的 0.04 micromol/L (P <
0.05 ) ,在全部的肉毒碱的 8.7 micromol/L (P <
0.001 ) 。在恶病质病人与或没有胃肠的癌症,差别是在免费肉毒碱的 12.2 micromol/L ( P <
0.001 ),在短链酰肉毒碱的 4.60 micromol/L ( P <
0.001 ),并且在长链的酰肉毒碱的 0.60 微摩尔 /L ( P <
0.005 )并且在全部的肉毒碱的 17.4 micromol/L ( P <
0.001 )。在有胃肠的癌症和健康控制题目的恶病质病人,差别是在免费肉毒碱的 15.5 micromol/L ( P <
0.001 ),在短链的酰肉毒碱的 5.2 微摩尔 /L ( P <
0.001 ),在长链酰肉毒碱的 1.0 micromol/L ( P <
0.001 ),并且在全部的肉毒碱的 21.8 micromol/L ( P <
0.001 )。结论:在终端的肉毒碱的低浆液层次肿瘤的病人由于减少的饮食的吸入极大地被减少并且损害了这种物质的内长的合成。这些低浆液肉毒碱层次也在癌症病人贡献极度瘦弱的前进。 | Mariano Malaguarnera Corrado Risino Maria Pia Gargante Giovanni Oreste Gloria Barone Anna Veronica Tomasello Mario Costanzo Matteo Angelo Cannizzaro | 2006 | World Journal of Gastroenterology2006，12，28： | 3 |
| 7 | Inflammation in Diabetic Nephropathy显示文摘 | Andy K. H. Lim Gregory H. Tesch Oreste Gualillo | 2012 | Mediators of Inflammation2012，，： | 2 |
| 8 | Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23–01): a phase 3 randomised controlled trial显示文摘 | Viviana Galimberti Bernard F Cole Stefano Zurrida Giuseppe Viale Alberto Luini Paolo Veronesi Paola Baratella Camelia Chifu Manuela Sargenti Mattia Intra Oreste Gentilini Mauro G Mastropasqua Giovanni Mazzarol Samuele Massarut Jean-Rémi Garbay Janez Zgajn | 2013 | Lancet Oncology2013，，4： | 2 |
| 9 | Compromised nutritional status in patients with end-stage liver disease:Role of gut microbiota显示文摘Background: Patients with end-stage liver disease(ESLD) have a compromised nutritional status because of the liver crucial role in regulating metabolic homeostasis and energy balance.Data sources: A systematic review of literature based on extensive relevant articles published from 2001 to 2017 in English in Pub Med database was performed by searching keywords such as liver disease, nonalcoholic liver disease, alcoholic liver disease, malnutrition, epigenetics, gut microbiota, and probiotics.Results: Liver transplantation would be one eligible therapy for ESLD patients, even if, the clinical outcome is negatively influenced by malnutrition and/or infections. The malnutrition is a condition of nutrient imbalance with a high incidence in ESLD patients. An accurate evaluation of nutritional status could be fundamental for reducing complications and prolonging the survival of ESLD patients including those undergoing liver transplantation. In addition, the interaction among nutrients, diet and genes via epigenetics has emerged as a potential target to reduce the morbidity and mortality in ESLD patients. The malnutrition induces changes in gut microbiota causing dysbiosis with a probable translocation of bacteria and/or pathogen-derived factors from the intestine to the liver. Gut microbiota contribute to the progression of chronic liver diseases as well as hepatocellular carcinoma. The administration of probiotics modulating gut microbiota could improve all chronic liver diseases.Conclusions: This review provides an update on malnutrition status linked to epigenetics and the potential benefit of some probiotics on the management of ESLD patients. In support of this view and to reveal the constant and growing interest in this field, some clinical trials are reported. | Maria Vasco Rossella Paolillo Concetta Schiano Linda Sommese Oreste Cuomo Claudio Napoli | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，4： | 2 |
| 10 | Platelet biomarkers in Alzheimer's disease显示文摘The search for diagnostic and prognostic markers in Alzheimer's disease(AD) has been an area of active research in the last decades. Biochemical markers are correlates of intracerebral changes that can be identified in biological fluids, namely: peripheral blood(total blood, red and white blood cells, platelets, plasma and serum), saliva, urine and cerebrospinal fluid. An important feature of a biomarker is that it can be measured objectively and evaluated as(1) an indicator of disease mechanisms(markers of core pathogenic processes or the expression of downstream effects of these processes), or(2) biochemical responses to pharmacological or therapeutic intervention, which can be indicative of disease modification. Platelets have been used in neuropharmacological models since the mid-fifties, as they share several homeostatic functions with neurons, such as accumulation and release of neurotransmitters, responsiveness to variations in calcium concentration, and expression of membrane-bound compounds. Recent studies have shown that platelets also express several components related to the pathogenesis of AD,in particular to the amyloid cascade and the regulation of oxidative stress: thus they can be used in the search for biomarkers of the disease process. For instance, platelets are the most important source of circulating forms of the amyloid precursor protein and other important proteins such as Tau and glycogen synthase kinase-3B. Moreover, platelets express enzymes involved in membrane homeostasis(e.g., phospholipase A2), and markers of the inflammatory process and oxidative stress. In this review we summarize the available literature and discuss evidence concerning the potential use of platelet markers in AD. | Leda L Talib Helena PG Joaquim Orestes V Forlenza | 2012 | World Journal of Psychiatry2012，2，6： | 2 |
| 11 | Back-analysis technique for the improvement of the understanding of rock in underground constructions显示文摘 | ORESTE P | 2005 | Tunnelling and Underground Space Technology2005，20，1： | 1 |
| 12 | Back-analysis techniques for the improvement of the understanding of rock in underground constructions显示文摘 | ORESTE P | 2005 | Tunnelling and Underground Space Technology2005，20，1： | 1 |
| 13 | Hepato-splenic gamma delta Tcell lymphoma: a rare entity mimicking the hemophagocytic syndrome 显示文摘 | Nosari A Oreste PL Biondi A | 1999 | Am J Hematol1999，60，： | 1 |
| 14 | Chemically sulfated Escherichia coli K5 polysaccharide derivatives as extracellular HIV - 1 tat protein antagonists显示文摘 | Urbinati C Bugatti A Oreste P | 2004 | FEBS Lett2004，568，1： | 1 |
| 15 | Experimental and Numerical Studies on Rock Breaking with TBM Tools under High Stress Confinement显示文摘 | N. Innaurato C. Oggeri P. P. Oreste R. Vinai | 2007 | Rock Mechanics and Rock Engineering2007，，5： | 1 |
| 16 | Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging显示文摘 | Paolo Pignoli Elena Tremoli Andrea Poli Pierluigi Oreste Rodolfo Paoletti | 1986 | Circulation1986，，6： | 1 |
| 17 | Modelling progressive hardening of shotcrete in convergence-confinement approach to tunnel design显示文摘 | P.P. Oreste D. Pella | 1997 | Tunnelling and Underground Space Technology incorporating Trenchless Technology Research1997，，： | 1 |
| 18 | Between subject variations of transition zone epithelial volume and serum PSA levels in men with benign prostatic hyperplasia显示文摘 | Oreste M Giuseppe PG Gianna P | 2010 | World J Urol2010，28，3： | 1 |
| 19 | Mucormycosis in hematologic malignancies:an emerging fungal infection显示文摘 | NOSARI A ORESTE P MONTILLO M | 2000 | Haematologica2000，85，10： | 1 |
| 20 | Theoretical study on the TBM tool-rock interaction显示文摘 | Innaurato N Oreste P | | Geotechnical and Geological Engineering0，19，： | 1 |
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