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| 1 | Evaluation of inflammatory activity in Crohn's disease and ulcerative colitis显示文摘Crohn's disease and ulcerative colitis evolve with a relapsing and remitting course.Determination of inflammatory state is crucial for the assessment of disease activity and for tailoring therapy.However,no simple diagnostic test for monitoring intestinal inflammation is available.Noninvasive markers give only indirect assessments of disease activity.Histopathological or endoscopical examinations accurately assess inflammatory activity,but they are invasive,time consuming and expensive and therefore are unsuitable for routine use.Imaging procedures are not applicable for ulcerative colitis.The usefulness of ultrasound and Doppler imag-ing in assessing disease activity is still a matter of discussion for Crohn's disease,and an increased interest in computed tomography enterograph (CTE) has been seen,mainly because it can delineate the extent and severity of bowel wall inflammation,besides detecting extraluminal findings.Until now,the available data concerning the accuracy of magnetic resonance enterography in detecting disease activity is less than CTE.Due to this,clinical activity indices are still commonly used for both diseases. | Eduardo Garcia Vilela Henrique Osvaldo da Gama Torres Fabiana Paiva Martins Maria de Lourdes de Abreu Ferrari Marcella Menezes Andrade Aloísio Sales da Cunha | 2012 | World Journal of Gastroenterology2012，18，9： | 23 |
| 2 | Relaxin prevents the development of severe acute pancreatitis显示文摘瞄准:为了调查尖锐胰腺炎(AP ) 的严厉,被联系到白血球激活,煽动性的起来规定和联系到 ischemia-reperfusion 损害的微循环混乱的紧张。支持 inflammatory 调停人的 Microvascular 完整和抑制在 AP 的进化是关键因素的。松弛激素是被归因的像胰岛素的荷尔蒙经由氮的氧化物小径的 vasorelaxant 性质当作为糖皮质激素受体收缩筋表现时。方法:AP 被 bilio 胰腺的 duct-outlet-exclusion closed-duodenal-loops 模型导致。有松弛激素的处理在不同时间点被做。由由 mifepristone 的阻塞被考虑的 L 名字和糖皮质激素受体(GR ) 的氮的氧化物 synthase 抑制。AP 严厉被生物化学、组织病理学说的分析估计。结果:有松弛激素的处理减少了浆液淀粉酶,脂肪分解酵素, C 反应的蛋白质, IL-6, IL-10, hsp72, LDH 和 8-isoprostane 象一样胰腺并且肺 myeloperoxidase。腺泡和脂肪坏死,出血和 neutrophil 渗透也被减少。当 caspases 2-3-8 和 9 项活动被增加时, ATP 弄空和 ADP/ATP 比率被减少。L 名字和 mifepristone 减少了松弛激素的效率。结论:松弛激素结果在当保存微发行量并且在坏死上赞成 apoptosis 时,联合 GR 收缩筋的性质的 AP 的处理有益。 | Laura Iris Cosen-Binker Marcelo Gustavo Binker Rodica Cosen Gustavo Negri Osvaldo Tiscornia | 2006 | World Journal of Gastroenterology2006，12，10： | 10 |
| 3 | 短链葡聚糖-姜黄素纳米乳液的制备及结构表征显示文摘利用短链葡聚糖(short glucan chains,SGC)的螺旋空间结构来包埋姜黄素(curcumin,CUR)。通过使用高剪切分散乳化机高速剪切溶液5 min,用纳米均质机在50 MPa压力下高压均质经剪切后的乳液2次制备成纳米乳液以提高其包埋率和载药量。XRD (x-ray diffraction)和TGA (thermogravimetric analysis)很好的验证了包合物的形成,通过TGA、SEM (scanning electron microscopy)、激光粒径分析仪等各种表征分析得出短链葡聚糖-姜黄素纳米乳液制备成功,所制得的乳液对姜黄素的包埋率和载药量都高于短链葡聚糖-姜黄素包合物,分别达到了71.11%和12.07%,说明制备成纳米乳液对姜黄素的包埋率和载药量都有了明显的提高。所制备的纳米乳液的粒径小于300 nm,粒径分布均一,Zeta电位观测表明所制得的乳液的稳定性有所提高。为提高食品及医药领域姜黄素的生物利用率提供了一定的参考意义。 | 冯涛 曾小兰 王珂 Osvaldo Campanella | 2019 | 农业工程学报2019，35，1： | 10 |
| 4 | A worldwide phylogenetic classification of the Poaceae (Gramineae)显示文摘基于最近的分子、词法的研究我们在场 the ± 12074 草和地方的一个现代全球种系发生的分类 771 个草类进 12 个亚科( Anomochlooideae , Aristidoideae , Arundinoideae , Bambusoideae , Chloridoideae , Danthonioideae , Micraioideae , Oryzoideae , Panicoideae , Pharoideae , Puelioideae ,和 Pooideae ), 6 supertribes ( Andropogonodae , Arundinarodae , Bambusodae , Panicodae , Poodae , Triticodae ), 51 个部落( Ampelodesmeae , Andropogoneae , Ano 另外,我们包括在 subtribes,部落,和亚科之中说明层次关系的一棵光线的树。我们使用 subfamilial 名字, Oryzoideae,因为后者是开始被出版,在 Ehrhartoideae 上,一个错放的等级,和我们约束 Molinieae 包括 13 个 Arundinoideae 类。subtribe Calothecinae 最新被描述,部落 Littledaleeae 在那个等级是新的。 | Robert J. Soreng Paul M. Peterson Konstantin Romaschenko Gerrit Davidse Fernando O. Zuloaga Emmet J. Judziewicz Tarciso S. Filgueiras Jerrold I. Davis Osvaldo Morrone | 2015 | Journal of Systematics and Evolution2015，53，2： | 10 |
| 5 | Biliary acute pancreatitis:a review显示文摘INTRODUCTIONIt is axiomatic that the most effective and soundlybased plan of treatment of any disorder is one aimedat the mechanism or mechanisms responsible for itsdevelopment.This basic notion,coupled withrecent reports in which,surprisingly there is atotal lack of reference to the probable involvementof autonomic-arc-reflexes in the | Osvaldo M.Tiscomia Susana Hamamura Enriqueta S.deLehmann Graciela Otero Hipolito Waisman Patricia Tiscornia-Wasserman Simmy Bank | 2000 | World Journal of Gastroenterology2000，6，2： | 6 |
| 6 | 三聚体纳米颗粒自组装过程的分子动力学模拟显示文摘为了更深入理解直链淀粉/β-乳球蛋白/α-亚油酸三元复合物体系自组装行为的机制,该研究借助Gromacs软件,采用分子动力学模拟对玉米直链淀粉、β-乳球蛋白、α-亚油酸三者在373 K温度下的结合过程进行研究。通过三元纳米粒子在500 ns内的自组装快照图,可以得出直链淀粉、α-亚油酸、β-乳球蛋白3种组分的结合顺序。通过三元纳米粒子的自由能曲面图,可知该三元纳米粒子的形成是热力学自发的过程。进一步对其水合半径及溶剂可接触表面积的分析表明,该三元复合物纳米颗粒溶解性良好。研究阐释了水溶性自组装纳米颗粒的形成机理,为纳米科学领域寻找合适的壁材提供了一种新的研究途径。 | 冯涛 王珂 周进杰 Deepak Bhopatkar 陈枫 Osvaldo Campanella Bruce R.Hamaker Marcelo Carignano 庄海宁 | 2017 | 农业工程学报2017，33，3： | 6 |
| 7 | Posterior partially edentulous jaws, planning a rehabilitation with dental implants显示文摘AIM: To discuss important characteristics of the useof dental implants in posterior quadrants and the rehabilitation planning. METHODS: An electronic search of English articles was conducted on MEDLINE(PubM ed) from 1990 up to the period of March 2014. The key terms were dental implants and posterior jaws, dental implants/treatment planning and posterior maxilla, and dental implants/treatment planning and posterior mandible. No exclusion criteria were used for the initial search. Clinical trials, randomized and non randomized studies, classical and comparative studies, multicenter studies, in vitro and in vivo studies, case reports, longitudinal studies and reviews of the literature were included in this review. RESULTS: One hundred and fifty-two articles met the inclusion criteria of treatment planning of dental implants in posterior jaw and were read in their entirety. The selected articles were categorized with respect to their context on space for restoration, anatomic considerations(bone quantity and density), radiographic techniques, implant selection(number, position, diameter and surface), tilted and pterygoid implants, short implants, occlusal considerations, and success rates of implants placed in the posterior region. The results derived from the review process were described under several different topic headings to give readers a clear overview of the literature. In general, it was observed that the use of dental implants in posterior region requires a careful treatment plan. It is important that the practitioner has knowledge about the theme to evaluate the treatment parameters. CONCLUSION: The use of implants to restore the posterior arch presents many challenges and requires a detailed treatment planning. | Douglas R Monteiro Emily V F Silva Eduardo P Pellizzer Osvaldo Magro Filho Marcelo C Goiato | 2015 | World Journal of Clinical Cases2015，3，1： | 6 |
| 8 | Physico-chemical properties and structure of rice cultivars grown in Heilongjiang Province of China显示文摘The relationships between chemical composition,structure and physicochemical properties such as pasting,thermal,and textural properties of 12 temperate rice cultivars grown in Heilongjiang Province,China were investigated in this study.There were significant differences in the content of fat,protein,ash,amylose,damaged starch among 12 cultivars.Brabender Viscograph results showed that gelatinization time,peak viscosity,pasting and peak temperature ranged from 9 min to 15 min,2100 BU to 2500 BU,58.75℃to 72.00℃and 63.75℃to 84.45℃,respectively,except for the waxy one Longjing 9.To,Tp,Tc andΔH were found in the range of 58.34℃to 67.96℃,65.39℃to 75.38℃,78.47℃to 90.69℃and 2.036 J/g to 3.127 J/g respectively.Scanning Electron Micro-photograph results showed that all starch granules were polyhedral with irregular shapes,except Longjing 9 showing signs of the loss of physical integrity.The hardness,adhesiveness,springiness,gumminess,cohesiveness and resilience ranged from 395.87 g to 1161.76 g,-90.842 g·mm to-36.4 g·mm,0.498 to 0.747,78.631 g to 466.837 g,0.199 to 0.569,0.321 to 0.504,respectively.Correlation studies indicated that amylose,damaged starch,protein,fat and ash played a more important role in determining the rice properties of pasting,thermal,crystallinity and texture. | Yinyuan He Fenglian Chen Yanguo Shi Zhexian Guan Na Zhang Osvaldo HCampanella | 2021 | Food Science and Human Wellness2021，10，1： | 5 |
| 9 | Weighted Weak-type Estimates for Multilinear Commutators of Fractional Integrals on Spaces of Homogeneous Type显示文摘我们在同类的类型的空格为部分积分的多线性的整流器获得加权的分布不平等。在这个工作开发的技术包含一些部分最大的功能的行为。在与这些操作员的关系,作为一个主要工具,我们证明一种加权的弱类型围住海角结果,它在自己有趣。 | Osvaldo GOROSITO Gladis PRADOLINI Oscar SALINAS | 2007 | Acta Mathematica Sinica,English Series2007，23，10： | 5 |
| 10 | Catalytic combustion of soot over ceria-zinc mixed oxides catalysts supported onto cordierite显示文摘Modified substrates as outer heterogeneous catalysts was employed to reduce the soot generated from incomplete combustion of diesel or diesel/biodiesel blends, a process that harms the environment and public health. The unique storage properties of ceria(CeO2) makes it one of the most efficient catalysts available to date. Here, we proposed that ceria-based catalysts can lower the temperature at which soot combustion occurs; more specifically, from 610℃ to values included in the diesel exhausts operation range(300–450℃). The sol-gel method was used to synthesize mixed oxide-based catalysts(CeO2:ZnO); the resulting catalysts were deposited onto cordierite substrates. In addition, the morphological and structural properties of the material were evaluated by XRD, BET, TPR-H2, and SEM. Thermogravimetric(TG/DTA) analysis revealed that the presence of the catalyst decreased the soot combustion temperature by 200℃ on average, indicating that the oxygen species arise at low temperatures in this situation, promoting highly reactive oxidation reactions. Comparative analysis of soot emission by diffuse reflectance spectroscopy(DRS) showed that catalyst-impregnated cordierite samples efficiently oxidized soot in a diesel/biodiesel stationary motor: soot emission decreased by more than 70%. | Leandro Fontanetti Nascimento Renata Figueredo Martins Rodrigo Ferreira Silva Osvaldo Antonio Serra | 2014 | Journal of Environmental Sciences2014，26，3： | 5 |
| 11 | Treatability studies of naphthalene in soil,water and air with persulfate activated by iron(Ⅱ)显示文摘Chemical oxidation was applied to an artificially contaminated soil with naphthalene(NAP).Evaluation of NAP distribution and mass reduction in soil,water and air phases was carried out through mass balance.Evaluation of NAP distribution and mass reduction in soil,water and air phases was carried out through mass balance.The importance of the air phase analysis was emphasized by demonstrating how NAP behaves in a sealed system over a 4 hr reaction period.Design of Experiments method was applied to the following variables:sodium persulfate concentration[SP],ferrous sulfate concentration[FeS04],and pH.The system operated with a prefixed solid to liquid ratio of 1:2.The following conditions resulted in optimum NAP removal[SP]=18.37 g/L,[FeSO4]=4.25 g/L and pH=3.00.At the end of the 4 hr reaction,62%of NAP was degraded.In the soil phase,the chemical oxidation reduced the NAP concentration thus achieving levels which comply with Brazilian and USA environmental legislations.Besides the NAP partitioning view,the monitoring of each phase allowed the variabilities assessment over the process,refining the knowledge of mass reduction.Based on NAP distribution in the system,this study demonstrates the importance of evaluating the presence of semi-volatile and volatile organic compounds in the air phase during remediation,so that there is greater control of the system as to the distribution and presence of the contaminant in the environment.The results highlight the importance of treating the contaminant in all its phases at the contaminated site. | Gabriela P.Mendes Vivian M.A.Magalhaes Lélia C·R·Soares Rayanne M.Aranha Claudio A.O.Nascimento Marilda M.G.R.Vianna Osvaldo Chiavone-Filho | 2020 | Journal of Environmental Sciences2020，32，4： | 4 |
| 12 | Short- and long-term efficacy of endoscopic balloon dilation in Crohn's disease strictures显示文摘AIM:To evaluate short- and long-term efficacy of endoscopic balloon dilation in a cohort of consecutive patients with symptomatic Crohn's disease (CD)-related strictures. METHODS:Twenty-six CD patients (11 men; median age 36.8 year, range 11-65 years) with 27 symptomatic strictures underwent endoscopic balloon dilation (EBD).Both naive and post-operative strictures, of any length and diameter, with or without associated fistula were included. After a clinical and radiological assessment, EBD was performed with a Microvasive Rigiflex through the scope balloon system. The procedure was considered successful if no symptom reoccurred in the following 6 mo. The long-term clinical outcome was to avoid surgery. RESULTS:The mean follow-up time was 40.7 ± 5.7 mo (range 10-94 mo). In this period, forty-six EBD were performed with a technical success of 100%. No procedure-related complication was reported. Surgery was avoided in 92.6% of the patients during the entire follow-up. Two patients, both presenting ileocecal strictures associated with fistula, failed to respond to the treatment and underwent surgical strictures resection. Of the 24 patients who did not undergo surgery, 11 patients received 1 EBD, and 13 required further dilations over time for the treatment of relapsing strictures (7 patients underwent 2 dilations, 5 patients 3 dilations, and 1 patient 4 dilations). Overall, the EBD success rate after the first dilation was 81.5%. No difference was observed between the EBD success rate for naive (n = 12) and post-operative (n = 15) CD related strictures (P > 0.05). CONCLUSION:EBD appears to be a safe and effective procedure in the therapeutic management of CD-related strictures of any origin and dimension in order to prevent surgery. | Nicola de'Angelis Maria Clotilde Carra Osvaldo Borrelli Barbara Bizzarri Francesca Vincenzi Fabiola Fornaroli Giuseppina De Caro Gian Luigi de'Angelis | 2013 | World Journal of Gastroenterology2013，19，17： | 4 |
| 13 | A Study of the Structural, Optical and Electrical Properties of SnS Thin Films Modified by Plasma显示文摘 | Aar6n Gomez Horacio Martinez Manuela Calixto-Rodriguez David Avellaneda Pedro Guillermo Reyes Osvaldo Flores | 2013 | 材料科学与工程(中英文B版)2013，3，6： | 3 |
| 14 | 分子动力学模拟研究直链淀粉与α-亚油酸的包合行为显示文摘α-亚油酸和直链淀粉可以形成热力学稳定复合物。为了研究α-亚油酸影响直链淀粉构象的机理、复合物的构象趋势及复合作用过程中氢键的变化情况,在373 K条件下进行了长时间(500 ns)的全原子分子动力学模拟。模拟发现在有/无α-亚油酸存在的情况下,在500 ns内都可以观察到大量有序到无序的构象转变,这表明直链淀粉和α-亚油酸之间结合作用微弱。原子均方根偏差(RMSD)、α-亚油酸与直链淀粉轴心间距、氢键增加都证明直链淀粉-α-亚油酸复合物的形成是热力学自发行为。 | 冯涛 王旭 庄海宁 Feng Chen Bruce R Hamaker Osvaldo Campanella 王凯 | 2016 | 中国粮油学报2016，31，4： | 3 |
| 15 | Effect of B Vitamins and Lowering Homocysteine on Cognitive Impairment in Patients With Previous Stroke or Transient Ischemic Attack: A Prespecified Secondary Analysis of a Randomized, Placebo-Controlled Trial and Meta-Analysis显示文摘 | Graeme J. Hankey Andrew H. Ford Qilong Yi John W. Eikelboom Kennedy R. Lees Christopher Chen Denis Xavier Jose C. Navarro Udaya K. Ranawaka Wasim Uddin Stefano Ricci John Gommans Reinhold Schmidt Osvaldo P. Almeida Frank M. van Bockxmeer | 2013 | Stroke2013，，8： | 2 |
| 16 | Construction of Dulac functions for mathematical models in population biology显示文摘 | Osvaldo Osuna Cruz Vargas-De-Leon | 2015 | International Journal of Biomathematics2015，8，3： | 2 |
| 17 | 短链葡聚糖包合姜黄素的分子机制显示文摘通过利用普鲁兰酶来酶解蜡质玉米淀粉而得到的短链葡聚糖来包合姜黄素,可以极大地提高姜黄素的水溶性。本研究还使用新型的计算机模拟的方法来分析短链葡聚糖和姜黄素的包合行为机制,模拟了短链葡聚糖-姜黄素包合物在600 ns内的分子包合行为。从模拟轨迹中获取的自组装快照图,可以知道包合物的结合方式是边解离边复合最后趋于稳定结构的包合方式。通过体系回转半径反应了短链葡聚糖随着时间与姜黄素包合行为过程中的构象变化,结果与快照图一致。体系溶解性较好,模拟得知的结果与实验基本一致,短链葡聚糖-姜黄素的溶解性高于单独的姜黄素水溶液,提高了姜黄素的生物利用率。为医学领域寻找合适的药物壁材提供了一种新的研究途径。 | 冯涛 曾小兰 张钰 Marcelo Carignano Osvaldo Campanella 李晓玺 | 2018 | 现代食品科技2018，34，10： | 2 |
| 18 | Reconstruction of debris-flow activity in a temperate mountain forest catchment of central Mexico显示文摘The use of dendrochronology to study and date geomorphic processes in volcanic environments is still incipient, even more so on the volcanic slopes covered by temperate forests in central Mexico. Mass movements, such as debris flows, often impact forest stands where they cause damage to individual trees, thereby generating growth disturbances(GD) in the tree-ring records. The identification and dating of GD enables reconstruction of the age of trees colonizing bare surfaces after major events, but also allows the assessment of the frequency or spatial distribution of past geomorphic process activity. Here we used increment cores from 65 Pinus leiophylla, Abies religiosa, and Alnus jorullensis trees growing in the Axal gorge, on the southern slopes of La Malinche volcano, to unravel past debris-flow activity both temporally and spatially. Based on the combination of GD records, a weighted tree response index(Wit), field evidence and hydrometeorological records, we reconstructed 23 debris flows since 1933.Interestingly, almost two-thirds of the reconstructed years with debris-flow activity in Axal gorge match with events recorded in Axaltzintle gorge located on the NE slopes of La Malinche. These findings suggest a regional triggering mechanism, most likely related to the occurrence of hurricanes. This research could be useful for disaster risk management of the La Malinche National Park. | Osvaldo FRANCO-RAMOS Markus STOFFEL Juan Antonio BALLESTEROS-CANOVAS | 2019 | Journal of Mountain Science2019，16，9： | 2 |
| 19 | Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease显示文摘 | Carlos Jose Pirola Tomas Fernández Gianotti Adriana Laura Burgue?o Manuel Rey-Funes Cesar Fabian Loidl Pablo Mallardi Julio San Martino Gustavo Osvaldo Casta?o S Sookoian | 2013 | Gut2013，，9： | 2 |
| 20 | Characterization of time dynamical evolution of electroencephalographic epileptic records显示文摘 | Maria Liliana Mairal | 2002 | Physica A2002，，： | 1 |
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