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460篇 您的检索式:作者名="OLIVIER L"
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1TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization显示文摘皮肤的神经原的发炎(CNI ) 是被导致的发炎(或提高) 在由从感觉神经末端的 neuropeptides 的版本的皮肤。临床的表明主要是象瘙痒和红斑那样的感觉、脉管的混乱。短暂受体潜力 vanilloid 1 并且 ankyrin 1 (TRPV1 和 TRPA1,分别地) 是知道明确地参予疼痛和 CNI 的非选择的阳离子隧道。TRPV1 和 TRPA1 在感觉神经的一个大子集被共同表示,在他们集成众多的有害刺激的地方。两条隧道的表示也在皮肤在感觉神经以外远延长,现在是清楚的,在 keratinocytes,桅杆房间,树枝状的房间,和 endothelial 房间也发生。在这些 non-neuronal 房间, TRPV1 和 TRPA1 也充当 nociceptive 传感器并且加强煽动性的过程。这评论在在感觉神经原和 non-neuronal 皮肤房间导致或维持 CNI 的煽动性的基因的调整讨论 TRPV1 和 TRPA1 的角色。另外,这评论由支持 CNI 的自我维护的另外的内长的煽动性的调停人提供关于两条 TRP 隧道的细胞内部的促进感受性小径的当前的研究的一篇摘要。Olivier Gouin Killian L'Herondelle Nicolas Lebonvallet Christelle Le Gall-lanotto Mehdi Sakka Virginie Buhe Emmanuelle PIee-Gautier Jean-Luc Carre Luc Lefeuvre Laurent Misery~,Raphaele Le Garrec 2017Protein & Cell2017,8,9:45
2白喉-破伤风-无细胞百日咳-b型流行性感冒嗜血杆菌联合疫苗对中国婴儿安全性和免疫原性的研究显示文摘目的评价白喉-破伤风-无细胞百日咳-b型流行性感冒嗜血杆菌联合疫苗(Diphtheria,Tetanus,Acellular Pertussis and Haemophilus Influenzae Type b Combined Vaccine;DTaP-Hib),对中国婴儿的安全性和免疫原性。方法通过一项安全性研究(研究A)和一项安全性及免疫原性研究(研究B),评价DTaP-Hib联合疫苗接种于3、4、5月龄婴儿的安全性及免疫原性,并与DTaP联合疫苗及Hib疫苗(DTaP+Hib)同时分别接种进行比较。结果共690名健康婴儿接受了DTaP-Hib联合疫苗或DTaP联合疫苗与Hib疫苗分别同时接种的基础免疫。DTaP-Hib联合疫苗的耐受性与DTaP联合疫苗+Hib疫苗分别接种一致,两组局部及全身不良反应发生率差异无统计学意义。在接种DTaP-Hib联合疫苗的受试者中,至少有97.5%在基础免疫后一个月产生了针对白喉、破伤风、Hib的血清学保护性抗体,以及对无细胞百日咳抗原的免疫应答。按照预先制订的标准,DTaP-Hib联合疫苗的免疫应答与DTaP联合疫苗+Hib疫苗分别接种免疫应答应的差异无统计学意义。结论DTaP-Hib联合疫苗接种后可获得预期的安全性和免疫原性。临床试验注册国家食品药品监督管理局《药物临床批件》2003L03331。李艳萍 张庶民 叶强 侯启明 李亚男 李红 徐颖华 马霄 刘幼平 陈晓玲 黄莉荣 Gunasekaran Ramakrishnan 李荣成 赵雷 唐海文 Olivier Van Der Meeren Hans L Bock 2010中国疫苗和免疫2010,16,2:7
3A Quasi-One-Dimensional CFD Model for Multistage Turbomachines显示文摘这篇论文的目的是介绍能模仿多级式的压缩机和汽轮机的静止、短暂的操作的一个快、可靠的 CFD 模型。这个分析工具基于一个行进时间的、有限卷的方法解决的 Euler 方程的一个改编版本。Euler 方程被包括表示片流动相互作用的来源术语扩大了。这些来源术语用速度三角形和 blading 的一个 row-by-row 代表被决定在中间跨度。液体越过每片排经历的损失和偏差被关联供应。产生流动解答者是仅仅基于机器几何学的一个表演预言工具,提供探索一台多级式的压缩机或汽轮机的全部典型地图的可能性。它的效率以中央处理器时间使联合它到一个优化算法或到一个煤气的汽轮机性能工具可能。不同测试用例为计算典型地图与试验性的相比为哪个是被介绍。Olivier Léonard Olivier Adam 2008Journal of Thermal Science2008,17,1:7
4Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study显示文摘Laurent Beaugerie Nicole Brousse Anne Marie Bouvier Jean Frédéric Colombel Marc Lémann Jacques Cosnes Xavier Hébuterne Antoine Cortot Yoram Bouhnik Jean Pierre Gendre Tabassome Simon Marc Maynadié Olivier Hermine Jean Faivre Fabrice Carrat 2009The Lancet . 2009 (9701)2009,,:4
5Selection of patients and staging of peritoneal surface malignancies显示文摘Peritoneal carcinomatosis (PC) is a common evolution of cancer of the gastrointestinal tract, and has been traditionally regarded as a terminal disease with short median survival. During the last 20 years, thanks to its favourable oncologic results, a new loco-regional therapeutic approach, combining cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC), has an important development. Due to its significant, but acceptable, morbidity and mortality, and high cost, this comprehensive management plan requires knowledgeable patient selection. Quantitative prognostic indicators are required to assess a patient’s eligibility. Large multicenter studies have identified several prognostic factors, which can be used for a better selection of patients who would benefit from the combination of cytoreductive surgery with HIPEC. Indications for treatment of PC with cytoreduction and HIPEC are now validated for several diseases: peritoneal mesothelioma, pseudomyxoma peritonei, PC from the appendix, and colorectal cancer. Indications are still under discussion for gastric and ovarian carcinomatosis. Computed tomography is the best radiological for staging the disease. The extent of peritoneal carcinomatosis is, however, difficult to evaluate preoperatively, and precise evaluation is most often performed during surgical exploration. Cytoreductive surgery associated with HIPEC for the treatment of peritoneal carcinomatosis should be performed for young patients with limited and resectable carcino-matosis, in specialized institutions involved in the management of peritoneal surface malignancies.Eddy Cotte Guillaume Passot Franois-Noёl Gilly Olivier Glehen 2010World Journal of Gastrointestinal Oncology2010,2,1:4
6Inheritance patterns of secondary symbionts during sexual reproduction of pea aphid biotypes显示文摘食草的昆虫经常怀有影响他们的生态学和进化的细菌的共生者。蚜虫招待应尽的 endosymbiont Buchnera,它为复制被要求,和其频率越过蚜虫人口变化的容许的共生者。这些似母亲播送了第二等的共生者特别地在豌豆蚜虫被学习了, Acyrthosiphon pisum,哪个港口穿上环境地依赖的效果的至少 8 不同细菌的种类(不数的 Buchnera ) 主人健康。特别地,这些共生者种类与豌豆蚜虫人口在特定的植物上喂被联系。尽管他们是继承的似母亲,这些细菌偶尔越过昆虫系被转移。如此的 nonmaternal 转移的一机制在性复制期间是到子孙的父亲的传播。迄今为止,第二等的共生者的传播在仅仅蚜虫系和 3 共生者种类的一把在蚜虫的性复制期间被调查了。更好描绘这个过程,我们通过包含属于 9 专业化主人的遗传因子型,和 117 个十字的 49 克隆的一个交叉实验在豌豆蚜虫的性复制期间调查了 7 共生者种类的继承模式。在子孙的共生者种类在从鸡蛋并且在以后的单性生殖的代孵化的 fundatrix 阶段与诊断质的 PCR 被检测。我们没发现共生者的父亲的传播的证实的案例到子孙,并且我们观察到特别共生者种(Serratia symbiotica ) 的母亲的传播是相当低效的。我们在尊重讨论这些观察到豌豆蚜虫的生态学。Jean Peccoud Joêl Bonhomme Frédérique Mahéo Manon de la Huerta Olivier Cosson Jean-Christophe Simon 2014Insect Science2014,21,3:4
7High rates of HBsAg seroconversion in HBeAg-positive chronic hepatitis B patients responding to interferon: A long-term follow-up study显示文摘Rami Moucari Anneke Korevaar Olivier Lada Michelle Martinot-Peignoux Nathalie Boyer Vincent Mackiewicz Agnes Dauvergne Ana C. Cardoso Tarik Asselah Marie-Hélène Nicolas-Chanoine Michel Vidaud Dominique Valla Pierre Bedossa Patrick Marcellin 2009Journal of Hepatology2009,,6:2
8Epidermal growth factor receptor and HER-3 restrict cell response to sorafenib in hepatocellular carcinoma cells显示文摘Marie-José Blivet-Van Eggelpo?l Hamza Chettouh Laetitia Fartoux Lynda Aoudjehane Véronique Barbu Colette Rey Sabrina Priam Chantal Housset Olivier Rosmorduc Christèle Desbois-Mouthon 2012Journal of Hepatology2012,,1:2
9Seismic fault preserving diffusion 显示文摘OLIVIER L SORIN P CHRISTIAN G 2007Journal of Applied Geo- physies2007,61,2:1
10Mass tuansfer,clearanceand plasma concentration of procalcitonin during continuousvenovenous hemofiltration in patients with septic shock andacute oliguric renal failure显示文摘Claude L Philippe C Olivier G 2003Critical Care2003,6,7:1
11Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c显示文摘Rosse T Olivier R Monney L 1998Nature1998,391,6666:1
12Prostaglandins antago- nistieally control Bax activation during apoptosis 显示文摘Lalier L Cartron PF Olivier C 2011Cell Death Differ2011,18,3:1
13Bcl-2 prolongs cell survival after Bax-induced release of cytochromec显示文摘Rosse T Olivier R Monney L 1998Nature1998,391,6666:1
14Bio-based high performance thermosets:Stabilization and reinforcement of eugenol-based benzoxazine networks with BMI and CNT显示文摘Dumas L Bonnaud L Olivier M 2015European Polymer Journal2015,67,:1
15显示文摘Chauvin Y Mussmann L Olivier H 1995Angew Chem Int Ed Engl1995,34,:1
16Ionic liquids and catalysis: Recent progress from knowledge to applica- tions显示文摘OLIVIER B H MAGNA L MORVAN D 2010Applied Catalysis A: General2010,373,12:1
17Hypersonic model testing in a shock tunnel 显示文摘Olivier H Gronig H Bozec A L 1995AIAA Journal1995,33,2:1
18Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c显示文摘Rossé T Olivier R Monney L 1998Nature1998,391,6666:1
19Bcl -2 prolongs cell survivalafter Bax - induced release of cytochrome c 显示文摘Rosse T Olivier R Monney L 1998Nature1998,391,6666:1
20Treatment of organic pollution in industrial saline wastewater:A literature review显示文摘OLIVIER L RENE' M 2006Water Research2006,40,:1
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