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| 1 | 薄荷油纳米乳液消化规律与稳定性研究显示文摘研究了薄荷油纳米乳液在体外模拟消化过程中乳液包埋对其平均粒径、ζ-电位、游离脂肪酸释放率以及薄荷醇生物可利用度的影响。激光扫描3D共聚焦显微镜观察薄荷油纳米乳液的显微结构,研究发现薄荷油完全被SPI包埋,纳米乳液液滴呈球状形态,表明大豆蛋白完整地吸附于纳米乳液的油-水界面处,呈现出核壳状结构。高压均质处理制备的薄荷油纳米乳液的游离脂肪酸释放率及薄荷醇生物可利用度远大于薄荷油的对照组。薄荷油纳米乳液在模拟胃消化阶段,乳液的平均粒径、ζ-电位均变大,乳液的微观结构表明消化体系出现液滴聚合现象;在模拟肠液消化后,薄荷油纳米乳液的界面蛋白被水解,油滴被消化,乳液的平均粒径减小、ζ-电位绝对值增加。通过多重光散射稳定性分析仪检测薄荷油纳米乳液的稳定性,薄荷油稳定性指数为2.8,且检测过程中并未出现乳液上浮和絮凝等现象。 | 王中江 张潇元 车佳玲 李杨 OLGA O B 江连洲 | 2018 | 农业机械学报2018，49，10： | 7 |
| 2 | Contribution of functional KIR3DL1 to ankylosing spondylitis显示文摘Increasing evidence points to a role for killer immunoglobulin-like receptors(KIRs)in the development of autoimmune diseases.In particular,a positive association of KIR3DS1(activating receptor)and a negative association of KIR3DL1(inhibitory receptor)alleles with ankylosing spondylitis(AS)have been reported by several groups.However,none of the studies analyzed these associations in the context of functionality of polymorphic KIR3DL1.To better understand how the KIR3DL1/3DS1 genes determine susceptibility to AS,we analyzed the frequencies of alleles and genotypes encoding functional(KIR3DL1*F)and non-functional(KIR3DL1*004)receptors.We genotyped 83 AS patients and 107 human leukocyte antigen(HLA)-B27-positive healthy controls from the Russian Caucasian population using a two-stage sequence-specific primer PCR,which distinguishes KIR3DS1,KIR3DL1*F and KIR3DL1*004 alleles.For the patients carrying two functional KIR3DL1 alleles,those alleles were additionally genotyped to identify KIR3DL1*005 and KIR3DL1*007 alleles,which are functional but are expressed at low levels.KIR3DL1 was negatively associated with AS at the expense of KIR3DL1*F but not of KIR3DL1*004.This finding indicates that the inhibitory KIR3DL1 receptor protects against the development of AS and is not simply a passive counterpart of the segregating KIR3DS1 allele encoding the activating receptor.However,analysis of genotype frequencies indicates that the presence of KIR3DS1 is a more important factor for AS susceptibility than the absence of KIR3DL1*F.The activation of either natural killer(NK)or T cells via the KIR3DS1 receptor can be one of the critical events in AS development,while the presence of the functional KIR3DL1 receptor has a protective effect.Nevertheless,even individuals with a genotype that carried two inhibitory KIR3DL1 alleles expressed at high levels could develop AS. | Ivan V Zvyagin Ilgar Z Mamedov Olga V Britanova Dmitriy B Staroverov Evgeni L Nasonov Anna G Bochkova Anna V Chkalina Alexei A Kotlobay Dmitriy O Korostin Denis V Rebrikov Sergey Lukyanov Yuri B Lebedev Dmitriy M Chudakov | 2010 | Cellular & Molecular Immunology2010，7，6： | 5 |
| 3 | Non-thermal food preservation: Pulsed electric fields 显示文摘 | Humberto Vega-Mercado Olga M B Qin B L | 1997 | Trends in Food Science& Technology1997，，8： | 2 |
| 4 | C - Jun N - terminal kinase is essential for growth of human T98G glioblastoma cells 显示文摘 | Olga P Myriam G Frederic B | 2000 | J Biol Chem2000，275，24： | 1 |
| 5 | Normal pressure hydrocephalus: a qualitative study on outcome显示文摘 | Paulo B Luisa A Olga R | 2013 | Arq Neuropsiquiatr2013，71，： | 1 |
| 6 | Induction of lymphocytes activated marker CD69 following exposure to chitosanand alginate biopolymers显示文摘 | OLGA B GERRIT B ADRIANODE S | 2007 | Int J Pharm2007，337，12： | 1 |
| 7 | Effect of specific interactions on structure property relationships of thermoplastic IPNs based on polyurethane and styrene-co-acrylic acid ionomers显示文摘 | Olga G Olga S Alexander B | 2007 | Macromolecular Symposia2007，254，1： | 1 |
| 8 | Characterisation of low-fat high-dietary fibre frankfurters显示文摘 | NURIA G M MARIA 1 A A OLGA M B | 1999 | Meat Science1999，52，： | 1 |
| 9 | Robot swarms in an uncertain world: Controllable adaptability显示文摘 | Olga B Shillerov A | 2005 | Int J of Advanced Robotic Systems2005，2，3： | 1 |
| 10 | Liver protective effect of ursodeoxy-cholic acid includes regulation of ADAM17 activity 显示文摘 | Halka B Karel C Olga Z | 2013 | BMC Gastroenterol2013，13，1： | 1 |
| 11 | Effect of the nature of carbon support on the formation of active sites in Pd/C and Ru/C catalysts for hydrogena- tion of furfural显示文摘 | Roman M Mironenko Olga B Belskaya Tatyana I Gulyaeva | 2015 | Catalysis Today2015，249，： | 1 |
| 12 | Wastewater recycling: Application of ozone based treatment to secondary effluents显示文摘 | Javier R Olga G Femando B | 2009 | Chemosphere2009，74，： | 1 |
| 13 | A natural clouding agent from orange peels obtained using polygalacturonase and cellulase 显示文摘 | Alexandre E B Robert C S F Olga M B | 2005 | Food Chemistry2005，92，1： | 1 |
| 14 | Improving estimates of heavy and extreme precipitation using daily records from european rain gauges 显示文摘 | Olga Z Clemens S Konstantin B | 2009 | Journal of Hydrometeorology2009，10，1： | 1 |
| 15 | Cross-coupling of vinyldisilacyclobutane with olefins catalyzed by 显示文摘 | Magdalena J Olga S Natalia B | 2005 | J Organomet Chem2005，690，10： | 1 |
| 16 | STM study of the geometric and electronic structure of ZnO (0001)-Zn, (000 i )-O, (10 i 0), and (11 0) surfaces显示文摘 | OLGA D LYNN A B ULRIKE D | 2002 | Surface Science2002，519，3： | 1 |
| 17 | Missing Value Estimation Methods for DNA Microarrays显示文摘 | Olga T Michael C Sherlock G Pat B Trevor H Robert T David B Russ B A | 2001 | Bioinformatics2001，17，： | 1 |
| 18 | Characterisation of low-fat high-dietary fibre frankfurters显示文摘 | Nuria G M Maria I A A Olga M B | 1999 | Meat Science1999，，52： | 1 |
| 19 | Synthesis of carbon-coated MgO nanoparticles显示文摘 | Alexander F Bedilo Jake Sigel M Olga B Koper | 2002 | J Mate Chem2002，12，： | 1 |
| 20 | Alpha-methylacyl-CoA racemase as a marker in the differential diagnosis of metanephric adenoma显示文摘 | Olgae S Hutchinson B Tickoo S K | 2006 | Mod Pathol2006，19，2： | 1 |
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