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| 1 | Magnetic resonance elastography is accurate in detecting advanced fibrosis in autoimmune hepatitis显示文摘To assess the value of magnetic resonance elastography(MRE) in detecting advanced fibrosis/cirrhosis in autoimmune hepatitis(AIH).METHODS In this retrospective study, 36 patients(19 treated and 17 untreated) with histologically confirmed AIH and liver biopsy performed within 3 mo of MRE were identified at a tertiary care referral center. Liver stiffness(LS) with MRE was calculated by a radiologist, and inflammation grade and fibrosis stage in liver biopsy was assessed by a pathologist in a blinded fashion. Two radiologistsevaluated morphological features of cirrhosis on conventional magnetic resonance imaging(MRI). Accuracy of MRE was compared to laboratory markers and MRI for detection of advanced fibrosis/cirrhosis.RESULTS Liver fibrosis stages of 0, 1, 2, 3 and 4 were present in 4, 6, 7, 6 and 13 patients respectively. There were no significant differences in distribution of fibrosis stage and inflammation grade between treated and untreated patient groups. LS with MRE demonstrated stronger correlation with liver fibrosis stage in comparison to laboratory markers for chronic liver disease(r = 0.88 vs-0.48-0.70). A trend of decreased mean LS in treated patients compared to untreated patients was observed(3.7 k Pa vs 3.84 k Pa) but was not statistically significant. MRE had an accuracy/sensitivity/specificity/positive predictive value/negative predictive value of 0.97/90%/100%/100%/90% and 0.98/92.3%/96%/92.3%/96% for detection of advanced fibrosis and cirrhosis, respectively. The performance of MRE was significantly better than laboratory tests for detection of advanced fibrosis(0.97 vs 0.53-0.80, P < 0.01), and cirrhosis(0.98 vs 0.58-0.80, P < 0.01) and better than conventional MRI for diagnosis of cirrhosis(0.98 vs 0.78, P = 0.002).CONCLUSION MRE is a promising modality for detection of advanced fibrosis and cirrhosis in patients with AIH with superior diagnostic accuracy compared to laboratory assessment and MRI. | Jin Wang Neera Malik Meng Yin Thomas C Smyrk Albert J Czaja Richard L Ehman Sudhakar K Venkatesh | 2017 | World Journal of Gastroenterology2017，23，5： | 15 |
| 2 | Heavy metal induced DNA changes in aquatic macrophytes: Random amplified polymorphic DNA analysis and identification of sequence characterized amplified region marker显示文摘Plants have been used as good bio-indicators and genetic toxicity of environmental pollution in recent years. In this study, aquatic plants Hydrilla verticillata and Ceratophyllum demersum treated with 10 μmol/L Cd, 5 μmol/L Hg, and 20 μmol/L Cu for 96 h, showed changes in chlorophyll, protein content, and in DNA profiles. The changes in DNA profiles included variation in band intensity, presence or absence of certain bands and even appearance of new bands. Genomic template stability test performed for the qualitative measurement of changes in randomly amplified polymorphic DNA (RAPD) profiles, showed significant effect at the given concentration of metals. Cloning and sequencing of bands suggested that these markers although may not be homologous to any known gene but its conversion as a sequence characterized amplified region (SCAR) marker is useful in detecting the effects of genotoxin agents. | Meetu Gupta Neera Bhalla Sarin | 2009 | Journal of Environmental Sciences2009，21，5： | 9 |
| 3 | Role of Small Bowel Follow-through in Diagnosing Inflammation of the Terminal Ileum in Pediatric Patients显示文摘 | Matthew Stenerson Eric Vittinghoff Melvin B Heyman Grace E Kim Neera Gupta | 2010 | Journal of Pediatric Gastroenterology and Nutrition2010，，4： | 2 |
| 4 | A polyacetylene gentiobioside from hairy roots of Lobelia inflate 显示文摘 | Ishimaru K Sadoshima S Neera S | 1992 | Phytochemistry1992，31，5： | 1 |
| 5 | Novel red phosphors for solid-state lighting: the system NaM ( WO4 ) 2-x ( MoO4 ) x : Eu3 3+ ( M = Gd, Y, Bi) 显示文摘 | Neera j S Kijima N Chee tham A K | 2004 | Chemical Physics Letters2004，387，： | 1 |
| 6 | Singlet oxygen mediated apoptosis by anthrone involving lysosomes and mi- tochondria at ambient UV exposure显示文摘 | SYED FA/Z MUJTABAA ASHISH DWIVEDIA NEERA YADAV | 2013 | Journal of Hazardous Materials2013，，： | 1 |
| 7 | Tannin production in cell cultures of Sapium sebiferum 显示文摘 | Neera S Ishimaru K | 1992 | Phytochemistry1992，31，3： | 1 |
| 8 | Tannin production in Sapium sebiferum callus cult ures显示文摘 | Neera S Arakawa H Ishimaru K | 1992 | Phytochemistry1992，31，12： | 1 |
| 9 | Sterols and steryl glycosides from Urtica dioica 显示文摘 | Neera Chaurasia Max Wichtl | 1987 | Journal of Natural Products1987，50，5： | 1 |
| 10 | Organic manure and urea effectt on metolachlor transport through packed soil column 显示文摘 | Neera S | 2003 | J Environ Qual2003，32，： | 1 |
| 11 | How Global is Global Civil Society?显示文摘 | Neera Chandhoke | 2005 | Journal of World-Systems Research2005，2005，： | 1 |
| 12 | Osteoblast response to phospholipid modified titanium surface显示文摘 | Arpan Satsangi Neera Satsangi Renee’ Glover Rajiv K Satsangi Joo L Ong | 2003 | Biomaterials2003，，25： | 1 |
| 13 | Study of physico-chemical characteristics of water bodies around Jaipur 显示文摘 | Neera Srivastava Meena Agrawal Anupama Tyagi | 2003 | Journal of Environmental Biology2003，24，2： | 1 |
| 14 | Cache based query optimization approach in distributed database 显示文摘 | Mantu Batra Neera Aggarwal Hemant | 2012 | Kumar Source: International Journal of Computer Science Issues2012，9，6： | 1 |
| 15 | Novel red phosphors for solid-state lighting:the system NaM (WO4)2-x(MoO4)x:Eu3+(M =Gd,Y,Bi)显示文摘 | NEERA J S KIJIMA N CHEETHAM A K | | 0，，1： | 1 |
| 16 | Adsorption of herbicides on coal fly ash from aqueous solutions 显示文摘 | Neera S | 2009 | Journal of Hazardous Materials2009，168，1： | 1 |
| 17 | Probing the Association of Pancreatitis in Inflammatory Bowel Disease显示文摘 | Arvind I. Srinath Neera Gupta Sohail Z. Husain | 2016 | Inflammatory Bowel Diseases2016，，： | 1 |
| 18 | Analysis of dichroic dye doped polyrner-dispersed liquid crystal materi- als for display devices 显示文摘 | KUMAR P NEERA J KANG S W | 2011 | Thin Solid Films2011，520，1： | 1 |
| 19 | Case Report: Aminocaproic Acid Used to Control Upper Gastrointestinal Bleeding in Radiation Gastritis显示文摘 | Neera Grover Arthur Johnson | 1997 | Digestive Diseases and Sciences1997，，5： | 1 |
| 20 | Analyzing the Effectiveness of Policy Implementation at the Local Level: A Case Study of Management of the 2009–2010 Drought in Yunnan Province, China显示文摘Several research efforts have focused primarily on policy implementation and improving innovative actions to address disaster risks. Discussions are ongoing on how to measure the effectiveness of policy implementation at the local level. But there is no definitive theory of effective policy implementation, and very few frameworks have been found acceptable as the basis of an analysis of the effectiveness of policy implementation, especially on droughts. Based on the 2009–2010 extreme drought in Yunnan, China, this article presents a modified framework to assess the effectiveness of policy implementation by defining policy, practice, and performance, as well as a feedback loop by which to share the lessons learned. Water conservancy projects in Luliang County and the agricultural diversity program in Longyang County in Yunnan Province were analyzed from a farmers' perspective. It was found that farmers are highly dependent on government policies and projects, and the effectiveness of policies is measured by short-term, immediate, and tangible benefits rather than long-term adaptation strategies. The results highlight the urgent need to reduce risks by developing better awareness about climate change and drought and its impacts, increased understanding of drought hazards, and implementation of appropriate measures for long-term adaptation. | Neera Shrestha Pradhan Yufang Su Yao Fu Liyun Zhang Yongping Yang | 2017 | International Journal of Disaster Risk Science2017，8，1： | 1 |
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