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| 1 | Inflammation, oxidative stress and renin angiotensin system in atherosclerosis显示文摘Atherosclerosis is a chronic inflammatory disease associated with cardiovascular dysfunction including myocardial infarction, unstable angina, sudden cardiac death, stroke and peripheral thromboses. It has been predicted that atherosclerosis will be the primary cause of death in the world by 2020. Atherogenesis is initiated by endothelial injury due to oxidative stress associated with cardiovascular risk factors including diabetes mellitus, hypertension, cigarette smoking, dyslipidemia, obesity, and metabolic syndrome. The impairment of the endothelium associated with cardiovascular risk factors creates an imbalance between vasodilating and vasoconstricting factors, in particular, an increase in angiotensin Ⅱ(Ang Ⅱ) and a decrease in nitric oxide. The renin-angiotensin system(RAS), and its primary mediator Ang Ⅱ, also have a direct influence on the progression of the atherosclerotic process via effects on endothelial function, inflammation, fibrinolytic balance, and plaque stability. Anti-inflammatory agents [statins, secretory phospholipase A2 inhibitor, lipoprotein-associated phospholipase A2 inhibitor, 5-lipoxygenase activating protein, chemokine motif ligand-2, C-C chemokine motif receptor 2 pathway inhibitors, methotrexate, IL-1 pathway inhibitor and RAS inhibitors(angiotensin-converting enzyme inhibitors)], Ang Ⅱ receptor blockers and ranin inhibitors may slow inflammatory processes and disease progression. Several studies in human using anti-inflammatory agents and RAS inhibitors revealed vascular benefits and reduced progression of coronary atherosclerosis in patients with stable angina pectoris; decreased vascular inflammatory markers, improved common carotid intima-media thickness and plaque volume in patients with diagnosed atherosclerosis. Recent preclinical studies have demonstrated therapeutic efficacy of vitamin D analogs paricalcitol in Apo E-deficient atherosclerotic mice. | Kazim Husain Wilfredo Hernandez Rais A Ansari Leon Ferder | 2015 | World Journal of Biological Chemistry2015，6，3： | 84 |
| 2 | Flexible ureteroscopy:Technological advancements,current indications and outcomes in the treatment of urolithiasis显示文摘The last 3 decades have witnessed great improvements in the technology and clinical applications of many minimally invasive procedures in the urological field.Flexible ureteroscopy(fURS)has advanced considerably to become a widely utilized diagnostic and therapeutic tool for multiple upper urinary tract pathologies.The most common indication for fURS is the treatment of upper urinary tract stones with the aid of Holmium:Yttrium Aluminium Garnet(YAG)laser lithotripsy.Advancements in endoscope technologies and operative techniques have lead to a broader application of fURS in the management of urolithiasis to include larger and more complex stones.fURS has proved to be an effective and safe procedure with few contraindications.Continued progression in fURS may increase its clinical applicability and supplant other procedures as the first line treatment option for urolithiasis. | Husain Alenezi John D.Denstedt | 2015 | Asian Journal of Urology2015，2，3： | 20 |
| 3 | Polymorphism of -765G > C COX-2 is a risk factor for gastric adenocarcinoma and peptic ulcer disease in addition to H pylori infection:A study from northern India显示文摘AIM: To investigate -765G > C COX-2 polymorphism and H pylori infection in patients with gastric adenocarcinoma, peptic ulcer disease (PUD) and non- ulcer dyspepsia (NUD). METHODS: We enrolled 348 adult patients (62 gastric adenocarcinoma, 45 PUD and 241 NUD) undergoing upper gastrointestinal endoscopy at two referral centers between September, 2002 and May, 2007. H pylori infection was diagnosed when any of the four tests (RUT, culture, histopathology and PCR) were positive. Genotyping for -765G > C polymorphism of COX-2 was performed by PCR-RFLP analysis. RESULTS: Frequency of C carrier had significantassociation with gastric adenocarcinoma as compared to NUD [77.4% vs 29%, P < 0.001, odds ratio (OR) 8.20; 95% confidence interval (95% CI), 4.08-16.47] and PUD (77.4% vs 31.1%, P < 0.001; OR 8.04; 95% CI, 3.25-19.90). Risk of gastric adenocarcinoma was significantly higher in patients having C carrier with (OR 7.83; 95% CI 3.09-19.85) and without H pylori infection (OR 7.06; 95% CI, 2.61-19.09). Patients with C carrier and H pylori infection had significant risk for the development of PUD (P < 0.001; OR 5.65; 95% CI, 2.07-15.34). CONCLUSION: -765G > C COX-2 polymorphism with or without H pylori could be a marker for genetic susceptibility to gastric adenocarcinoma. COX-2 polymorphism in presence of H pylori infection might be useful in predicting the risk of PUD. | Ashish Saxena Kashi Nath Prasad Uday Chand Ghoshal Monty Roshan Bhagat Narendra Krishnani Nuzhat Husain | 2008 | World Journal of Gastroenterology2008，14，10： | 18 |
| 4 | 洱海流域不同施肥模式对稻田氮磷径流流失的影响显示文摘为探究洱海流域水稻种植的合理施肥模式,减少稻田氮磷径流流失,通过田间小区试验,研究不同施肥模式对稻田氮磷径流流失和水稻产量的影响。结果表明:与常规施肥处理(CF)相比,化肥减量20%处理(T1)总氮径流流失量无显著差异,有机肥替代处理(T2~T5)总氮径流流失量降低31.6%~40.4%,缓控释肥处理(T6)总氮径流流失量降低15.7%;与CF处理相比,T1、T2和T6处理总磷径流流失量无显著差异,T3和T5处理总磷径流流失量分别降低23.3%和17.4%,T4处理总磷流失量增加57.0%。与CF处理相比,T6处理和T1处理籽粒产量无显著差异,T2~T5处理籽粒产量降低11.8%~42.9%;与T1处理相比,T5和T3处理籽粒产量无显著差异。与CF处理相比,T1、T6和T4处理秸秆产量无显著差异,T2、T3和T5处理秸秆产量分别降低15.5%、16.0%和36.0%。综合考虑不同施肥处理的稻田径流流失量和水稻产量等因素,化肥减量(T1)、有机无机配施(T3和T5)和缓控释肥(T6)处理是可供选择的环境友好型施肥模式。 | 姜海斌 沈仕洲 谷艳茹 于双 邹洪涛 Arif Husain 张磊 张克强 | 2021 | 农业环境科学学报2021，40，6： | 17 |
| 5 | A review on therapeutic potential of Nigella sativa:A miracle herb显示文摘Nigella sativa(N.sativa)(Family Ranunculaceae)is a widely used medicinal plant throughout the world.It is very popular in various traditional systems of medicine like Unani and Tibb,Ayurveda and Siddha.Seeds and oil have a long history of folklore usage in various systems of medicines and food.The seeds of N.saliva have been widely used in the treatment of different diseases and ailments.In Islamic literature,it is considered as one of the greatest forms of healing medicine.It has been recommended for using on regular basis in Tibb-e-Nabwi(Prophetic Medicine).It has been widely used as antihypertensive,liver tonics,diuretics,digestive,anti-diarrheal,appetite stimulant,analgesics,anti-bacterial and in skin disorders.Extensive studies on N.sativa have been carried out by various researchers and a wide spectrum of its pharmacological actions have been explored which may include antidiabetic,anticancer,immunomodulator,analgesic,antimicrobial,anti-inflammatory,spasmolytic,bronchodilator,hepato-protective,renal protective,gaslro-prolective,antioxidant properties,etc.Due to its miraculous power of healing,N.sativa has got the place among the top ranked evidence based herbal medicines.This is also revealed that most of the therapeutic,properties of this plant are due to the presence of thymoquinone which is major bioactive component of the essential oil.The present review is an effort to provide a detailed survey of the literature on scientific researches of pharmacognostical characteristics,chemical composition and pharmacological activities of the seeds of this plant. | Aftab Ahmad Asif Husain Mohd Mujeeb Shah Alam Khan Abul Kalam Najmi Nasir Ali Siddique Zoheir A.Damanhouri Firoz Anwar | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，5： | 16 |
| 6 | Virological course of hepatitis A virus as determined by real time RT-PCR: Correlation with biochemical, immunological and genotypic profiles显示文摘瞄准:承担肝炎 A 的分析,并且相关病毒的负担,丙氨酸 aminotransferase (中高音) ,和有病毒血的持续时间的病毒的遗传型有控制调停房间的免疫的 CD4 (+)/ CD8 (+) 淋巴细胞人口的这些参数。方法:房间计数用用荧光在乙二胺四乙酸小瓶收集的新鲜全血被执行激活的房间 sorter。肝炎 A 病毒(HAV ) RNA 从血浆液被提取,抄录进 cDNA 并且由实时聚合酶链反应确定了并且是 genotyped 的颠倒。结果:在 11 个病人之中, 10 能完全被分析。这些, 3 有严重尖锐肝炎(s -- 啊) 并且剩余物有自我限制尖锐肝炎 A (啊哈) ,在第 4 d 上与有暴发性的疾病(脑病等级 IV ) 的一个病人一起死。中高音水平在啊哈两个都是显著地更高的(1070.9 +/- 894.3;P = 0.0014 ) 并且 s -- 啊(1713.9 +/- 886.3;P = 0.001 ) 与正常控制相比(23.6 +/- 7.2 ) 。在 s 的前凝血酶时间 -- 啊病人(21.0 +/- 2.0;P = 0.02 ) 比在啊哈显著地高(14.3 +/- 1.1;P = 0.44 ) 。在啊哈病人的 CD4 (+)/CD8 (+) 比率(1.17 +/- 0.11;P = 0.22 ) 并且 s -- 啊(0.83 +/- 0.12;P = 0.0002 ) 比在正常健康控制(1.52 ) 看低。有的自我限制盒子达到顶点在分析的开始的病毒的负担当时在 s -- 啊病人这发生在第 15 或第 30 d。在敏锐、严格的组,一耐心的各个属于遗传型 IA,与仍然是 8 个盒子属于遗传型 IIIA。唯一的暴发性的肝的失败大小写属于遗传型 IA。在自我限制感染的全部功课期间收集的 HAV 病毒的负担和中高音价值直接为 s 被相关,但是这不是事实 -- 啊病人。结论:基于小规模的研究, s 的固执地更高的病毒的负担 -- 啊可能由于减少的细胞免疫和溶血。病毒血的持续时间依赖于主人,当病毒的遗传型没在 AVH 和 s 的临床的结果有明显的角色 -- 啊盒子。 | Zahid Hussain Bhudev C Das Syed A Husain Sunil K Polipalli Tanzeel Ahmed Nargis Begum Subhash Medhi Alice Verghese Mohammad Raish Apiradee Theamboonlers Yong Poovorawan Premashis Kar | 2006 | World Journal of Gastroenterology2006，12，29： | 10 |
| 7 | Alcohol-induced hypertension: Mechanism and prevention显示文摘Epidemiological, preclinical and clinical studies es-tablished the association between high alcohol con-sumption and hypertension. However the mechanism through which alcohol raises blood pressure remains elusive. Several possible mechanisms have been pro-posed such as an imbalance of the central nervous system, impairment of the baroreceptors, enhanced sympathetic activity, stimulation of the renin-angio-tensin-aldosterone system, increased cortisol levels, increased vascular reactivity due to increase in intracel-lular calcium levels, stimulation of the endothelium to release vasoconstrictors and loss of relaxation due to inflammation and oxidative injury of the endothelium leading to inhibition of endothelium-dependent nitric oxide production. Loss of relaxation due to inflamma-tion and oxidative injury of the endothelium by angio-tensin II leading to inhibition of endothelium-dependent nitric oxide production is the major contributors of the alcohol-induced hypertension. For the prevention of alcohol-induced hypertension is to reduce the amount of alcohol intake. Physical conditioning/exercise trainingis one of the most important strategies to prevent/treat chronic alcohol-induced hypertension on physiological basis. The efficacious pharmacologic treatment includes the angiotensin-converting enzyme(ACE) inhibitors or angiotensin Ⅱ type 1 receptor blockers(ARBs) which have antioxidant activity and calcium channel blockers. The most effective prevention and treatment of alcohol-induced hypertension is physical exercise and the use of ACE inhibitors or ARBs in the | Kazim Husain Rais A Ansari Leon Ferder | 2014 | World Journal of Cardiology2014，6，5： | 8 |
| 8 | PI3K signaling pathway targeting by using different molecular approaches to treat cancer显示文摘Recent evidence of research has been proposed that the phosphoinositide 3-kinase(PI3K) pathway is noticeable target for searching novel anticancer agents. The phosphoinositide 3-kinase(PI3K) is accountable for harmonizing a diverse range of cell functions, such as transcription, proliferation, cell survival, cell growth, degranulation, vesicular trafficking and cell migration, which are mostly involved in carcinogenesis. Particularly, PI3K-mediated signaling molecules and its effects on gene expression contribute to tumorigenesis. PI3Ks generally are grouped into three distinct classes: Ⅰ, Ⅱ and Ⅲ according to their structure and function. The class IA of PI3K includes an alpha, beta or delta p110 catalytic subunit(p110α, p110β, or p110γ), which are associated with the activation of RTKs. Mutations in PIK3CA, the gene encoding the p110α catalytic subunit of PI3K, have just been recognized as novel mechanisms of inducing oncogenic PI3K signaling. Therefore, the class IA PI3K is the only one of most evidently implicated in cancer. The PI3K pathway is mostly mutated in more cancer patients compared with normal person, making it an eyecatching molecular target for analyses based on inhibitor molecule. In this article, we highlighted the signaling effects and regulation pathway of PI3K involved in the development and survival of tumor cells. The consequence and intricacy of PI3K pathway made it an essential beneficial target for cancer treatment. | Mohammad Rashid Shahid Karim Babar Ali Shamshir Khan Makhmur Ahmad Asif Husain Ravinesh Mishra | 2017 | Journal of Chinese Pharmaceutical Sciences2017，26，9： | 7 |
| 9 | 联合应用沙利度胺和脂质体阿霉素治疗复发性卵巢上皮性癌和腹膜癌的初步研究显示文摘目的:评价联合应用沙利度胺与脂质体阿霉素治疗复发性卵巢上皮性癌和腹膜癌的疗效和毒副作用。方法:将9例经手术和术后泰素+卡铂化疗后复发患者纳入本研究。每4周予以脂质体阿霉素30~50mg/m^2化疗,共3~8个疗程;同时每日予以沙利度胺100~300mg,其剂量从100mg/d开始,此后每2周增加50~100mg。通过体检、影像学检查和测定CA125水平评价治疗效果。结果:9例患者的中位年龄为56岁(35~81岁),FIGO分期为ⅢB~Ⅳ期。本次化疗的中位疗程数是6个疗程。中位随访时间为18.5个月。最常见的不良反应为疲劳(55.6%)和神经系统症状(55.6%)。3例患者出现Ⅲ度副反应,1例为无力、1例过敏性皮疹和1例末梢神经感觉异常。根据RECIST标准评价有病灶的6例患者疗效,2例部分缓解,2例治疗中疾病无进展,1例病情进展,1例失访。另有2例CA125升高的患者,在联合化疗3~4个疗程后CA125水平降低50%以上。1例二次肿瘤细胞减灭术后化疗的患者治疗后随访36个月无肿瘤复发迹象。在随访的8例患者中,中位疾病无进展时间为6.5个月(0~36个月);中位总的生存时间为20.5个月(8~36个月)。结论:联合应用沙利度胺与脂质体阿霉素治疗复发性卵巢上皮性癌具有可接受的毒副作用,同时具有一定的治疗效果。 | 郭红燕 Nelson N. Teng John K. Chan Amreen Husain Deirdre Stieglitz Jonathon S Bereck | 2008 | 现代妇产科进展2008，17，2： | 5 |
| 10 | 急性原发性房角关闭的脉络膜扩张机制:发病最初2周的生物测量指标变化研究 | Aung T. Husain R. 邢咏新 | 2005 | 世界核心医学期刊文摘(眼科学分册)2005，0，8： | 4 |
| 11 | Potential of plant polyphenol oxidases in the decolorization and removal of textile and non-textile dyes显示文摘在一个努力被作了到使用的这研究种多酚 oxidases ;土豆{日光浴室 tuberosum )并且 brinjal {日光浴室 melongena ),为在纺织品和另外的 industries.The 硫酸铵 fractionated 酶的各种各样的重要 dyesused 的处理,最大地在对待的 dyeswere 的各种各样的试验性的 conditions.Majority 下面对待很多染料的准备 wereused 在 pH 将染料的 3.0 .Some 脱色快速被将脱色而其它 weremarginally decolorized.The | AMJAD ALI Khan QAYYUM Husain | 2007 | Journal of Environmental Sciences2007，19，4： | 4 |
| 12 | Chronic ethanol and nicotine interaction on rat tissue antioxidant defense system显示文摘 | Kazim Husain Benjamin R. Scott Sathya K. Reddy Satu M. Somani | 2001 | Alcohol2001，，2： | 4 |
| 13 | Partial Protection by Lipoic Acid Against Carboplantin-induced Ototoxicity in Rats显示文摘Objective To investigate the alterations in auditory brainstem evoked responses (ABRs) and the changes of carboplatin-induced ototoxicity in the cochlear oxidant/antioxidant systems and otoprotection by an antioxidant lipoate. Methods Male wistar rats were divided into four groups and treated as follows: 1) vehicle (saline) control, 2) carboplatin (256 mg/kg, i.p.), 3) lipoate (100 mg/kg, i.p.), 4) lipoate + carboplatin. Post-treatment ABRs were performed after four days and rats were sacrificed with their cochleae harvested and analyzed. Results Carboplatin significantly elevated ABR threshold above the pretreatment thresholds. Lipoate+carboplatin treated rats showed decreased elevation of hearing threshold. Carboplatin significantly depleted cochlear reduced to oxizized glutathione (GSH/GSSG) ratio, whereas lipoate+carboplatin treatment increased GSH/GSSG ratio. Carboplatin significantly decreased cochlear copper zinc-superoxide dismutase (CuZn-SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and glutathione-S-transferase (GST) activities and enzyme protein expressions and a significant increase in Mn-SOD activity, protein expression and malondialdehyde (MDA) level. Cochlear antioxidant enzyme activities, enzyme protein expressions and MDA level were partially restored in lipoate+carboplatin treated rats, compared to carboplatin alone. Conclusion Carboplatin-induced ototoxicity is related to impairment of cochlear antioxidant system and otoprotection conferred by lipoate is associated with partial sparing of the cochlear antioxidant defense system. | KAZIM HUSAIN CRAIG WHITWORTH SATU M. SOMANI LEONARD P. RYBAK | 2005 | Biomedical and Environmental Sciences2005，18，3： | 3 |
| 14 | Evaluation of immunogenicity and reactogenicity of recombinant DNA hepatitis B vaccine produced in India显示文摘AIM: (1) To gain information on immune responses to an accelerated schedule of 0, 1, and 2 mo in paramedical staff and BDS students who are at an increased risk of getting hepatitis B infection and come under high risk groups. (2) To assess the efficacy and safety of EnivacHB in different age groups, using genetically modified yeast strain Pichia pastoris, a new recombinant hepatitis B vaccine developed and manufactured in India.METHODS: A prospective, comparative, and single blinded trial of rapid (0, 1, and 2 mo) hepatitis B immunization schedulewas reported. A total of three hundred and seven (212 females and 95 males) healthy volunteers divided into three age groups (18-29, 30-39,and 40-49) were enrolled after screening for markers of hepatitis B. All the volunteers received 20 mg of the vaccine intramuscularly at 0, 1, and 2 mo.RESULTS: Geometric mean titers were calculated pre and post vaccination. Before immunization the GMT was 0.0124 mIU/mL. One month after the administration of the third dose of recombinant vaccine 296/307 (96.5%)subjects achieved seroprotective levels of anti-HBs. The geometric mean anti-HBs titers achieved after one month of the third dose was 2 560.0 mIU/mL. The geometric mean anti-HBs titer of males was 2 029.0 mIU/mL, while that of the females was 2 759.0 mIU/mL. In the age group of 18-29 years, anti-HBs titer was 3 025.0 mIU/mL, while that in the age group of 30-39 years was 2096.0 mIU/mL. In third age group of 40-49 years, antiHBs titer was 1 592.0 mIU/mL. Hyper-responses (antiHBs≥100 mIU/mL) were shown in 88.0% (271/307) of subjects. Eleven (3.5%) subjects responded poorly to the vaccine in the age group of 40-49 years. There was only mild pain at the site of injection otherwise there were no other adverse drug reactions (ADRs).CONCLUSION: This vaccine (Enivac-HB) is safe and efficacious, providing significant protection after the third dose and rapid hepatitis B immunization schedule of 0, 1, and 2 mo can be recommended whenever rapid protection is the goal. | Zahid Hussain Syed S Ali Syed A Husain Mohammad Raish Deepika R Sharma Premashis Kar | 2005 | World Journal of Gastroenterology2005，11，45： | 3 |
| 15 | 深圳某社区娱乐场所女性从业人员艾滋病/性病认知现状分析显示文摘目的了解深圳市社区娱乐场所女性从业人员艾滋病/性病知识水平,为政府决策提供参考依据,以实施有效的干预。方法收集整理某社区娱乐场所265名女性从业人员艾滋病/性病知识问卷,并进行统计学分析。结果娱乐场所从业人员大部分未婚为主,高中/中专文化程度,来自农村,93.6%听说过艾滋病,70.6%认为“艾滋病病毒感染者无症状也能传染”。从业人员对淋病、梅毒、艾滋病有较高的认知率,但对尖锐湿疣、生殖器疱疹、非淋菌性尿道炎及软下疳等认知率较低;大部分了解艾滋病的三条传播途径,但对日常生活不传播艾滋病存在着认识误区;72.5%的从业人员知道正确使用安全套能有效预防艾滋病,但实际安全套使用率低;接受过艾滋病病毒检测的仅占6.8%;生殖器部位异常时,77.4%会选择去公立医院或国家指定的专科医疗机构看医生。结论社区娱乐场所女性从业人员艾滋病/性病的知识欠缺,导致安全套的使用率低,在社区娱乐场所广泛开展有针对性的艾滋病/性病健康教育,促进安全性行为,倡导正确的求医,有效地预防艾滋病/性病的流行。 | 郭平 洪福昌 程锦泉 张丹 张英姬 文立章 蔡于茂 Lewis Husain 周华 | 2005 | 岭南皮肤性病科杂志2005，12，2： | 3 |
| 16 | Quantification of total phenol,flavonoid content and pharmacognostical evaluation including HPTLC fingerprinting for the standardization of Piper nigrum Linn fruits显示文摘Objective:To carry out the physicochemical and phytochemical standardization with high performance thin layer chromatography fingerprinting of Piper nigrum L.(P.nigrum)fruits in order to ascertain the standard pharmacognostical parameters of this king of spices.Methods:Many standardization parameters like extractive values,total ash value,water soluble ash value and acid insoluble ash,moisture content,loss on drying and pH values of P.nigrum L.fruits were analyzed.The method of Harborne was adopted for the preliminary phytochemicals screening.Analysis of total phenolic and flavonoid contents,pesticides residues,aflatoxin and heavy metals were also performed.CAMAG-high performance thin layer chromatography system was used for fingerprinting of methanolic extract of P.nigrum L.fruits.Results:The results of phytochemicals testing indicated the presence of carbohydrates,phenolic compounds,flavonoids,alkaloids,proteins,saponins,lipids,sterols and tannins in various solvent extracts.Total phenolic and flavonoid contents in methanolic extract were found to be 1.728 1 mg/g and 1.087 ug/g,respectively.Heavy metals concentrations were found to be within standard limits.Aflatoxins and pesticides residues were absent.Conclusions:The outcome of this study might prove beneficial in herbal industries for identification,purification and standardization of P.nigrum L.fruits. | Aftab Ahmad Asif Husain Mohd Mujeeb Shah Alam Khan Hani Abdullah Anber Alhadrami Anil Bhandari | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，2： | 3 |
| 17 | Scavenging Action of Zinc and Green Tea Polyphenol on Cisplatin and Nickel Induced Nitric Oxide Generation and Lipid Peroxidation in Rats显示文摘Objective Toxic metal ions have been implicated in the generation of reactive oxygen species (ROS) and nitric oxide (NO). Metallothionines (MT) and plant flavonoids have been reported in the intervention against oxidative damage. We investigated the effect of zinc induced MT and green tea polyphenol (GTP) in reducing the oxidative responses induced by nickel and platinum. Methods Zinc (10 mg/kg b. wt, sc) was administered to rats twice at a gap of 24hrs and GTP (10 mg/100 mL in drinking water) was fed ad libitum for 8 days. Nickel chloride (150 umol/kgb.wt, ip) and cisplatin (50 mmol/kg b.wt, sc) was administered to rats 24 h after Zn or GTP pre-treatment. Animals of all the groups were sacrificed 16 hrs after treatment and biochemical markers for toxicity were monitored. Results Zinc or GTP pre-treatment caused significant protection against nickel or cisplatin enhanced mortality in rats, and reduction in lipid peroxidation and NO. Conclusion It is proposed that inhibition of ROS and NO by GTP and zinc may prove useful as a selective pharmacological agent in the amelioration of metal toxicity. | SEEMA JOSHI S. K. HASAN RAMESH CHANDRA M. M. HUSAIN R. C. SRIVASTAVA | 2004 | Biomedical and Environmental Sciences2004，17，4： | 3 |
| 18 | 无机盐类的胎盘转运显示文摘钙、磷、镁三种具有骨化作用的无机盐类均可经胎盘主动转运,而且在妊娠晚期转运速率明显增加。母体和胎儿的胎盘血流,以及母体和胎儿各自的钙浓度、1,25(OⅡ),2D_3、PTⅡ和PTⅡrP可能为钙转运的调节因素。胎盘对磷的摄取为钠依赖性的,且可因缺氧和为代谢毒物所减少;其转运可被PTⅡ而减少且受pH、温度、钠和氨基酸浓度的调节。同样,镁的转运具有温度依赖性,同时依靠钠、镁离子的交换。三种无机盐类转运的程度均具有种属差异,转运的启动机制尚不清楚。 | Husain SM Mughal MZ 毛健 | 1993 | 国外医学(儿科学分册)1993，20，2： | 2 |
| 19 | Comparative assessment of maximum power point tracking procedures for photovoltaic systems显示文摘The fast growing demands and increasing awareness for the environment, PV systems are being rapidly installed for numerous applications.However, one of the important challenges in utilizing a PV source is the maximum power harnessing using various maximum power point tracking techniques available. With the large number of MPPT techniques, each having some merits and demerits, confusion is always there for their proper selection. Discussion on various proposed procedures for maximum power point tracking of photovoltaic array has been done. Based on different parameters analysis of MPPT techniques is carried out. This assessment will serve as a suitable reference for selection, understanding different ways and means of MPPT. | Mohammed Aslam Husain Abu Tariq Salman Hameed M.Saad Bin Arif Abhinandan Jain | 2017 | Green Energy & Environment2017，2，1： | 2 |
| 20 | Synthesis of Mesoporous Lanthanum Phosphate and Its Use as a Novel Sorbent显示文摘Mesoporous 镧磷酸盐被综合由超分子在磷的酸的 cetyltrimethylammonium 溴化物和镧硝酸盐追随者消化自己组装。TGA-DTA, XRD 和 SEM 被采用学习 uncalcined 并且锻烧材料。 Cr ( III )的吸着行为, Mn ( II ), Fe ( III ),公司( II ), Ni ( II ), Cu ( II ), Zn ( II ), Cd ( II ), Ba ( II ), Hg ( II )和 Pb ( II )阳离子在水里在如此的材料上被学习, 3 摩尔晥楦楣湥? | ANBIA, Mansur ROFOUEI, Mohammad K. HUSAIN, Syed Waqif | 2006 | Chinese Journal of Chemistry2006，24，8： | 2 |
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