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| 1 | Primer containing dimethylaminododecyl methacrylate kills bacteria impregnated in human dentin blocks显示文摘Antibacterial dimethylaminododecyl methacrylate(DMADDM) was recently synthesized. The objectives of this study were to:(1)investigate antibacterial activity of DMADDM-containing primer on Streptococcus mutans impregnated into dentin blocks for the first time, and(2) compare the antibacterial efficacy of DMADDM with a previous quaternary ammonium dimethacrylate(QADM).Scotchbond Multi-Purpose(SBMP) bonding agent was used. DMADDM and QADM were mixed into SBMP primer. Six primers were tested: SBMP control primer P, P+2.5% DMADDM, P+5% DMADDM, P+7.5% DMADDM, P+10% DMADDM, and P+10% QADM.S. mutans were impregnated into human dentin blocks, and each primer was applied to dentin to test its ability to kill bacteria in dentinal tubules. Bacteria in dentin were collected via a sonication method, and the colony-forming units(CFU) and inhibition zones were measured. The bacterial inhibition zone of P+10% DMADDM was 10 times that of control primer(Po0.05). CFU in dentin with P+10% DMADDM was reduced by three orders of magnitude, compared with control. DMADDM had a much stronger antibacterial effect than QADM, and antibacterial efficacy increased with increasing DMADDM concentration. Dentin shear bond strengths were similar among all groups(P40.1). In conclusion, antibacterial DMADDM-containing primer was validated to kill bacteria inside dentin blocks, possessing a much stronger antibacterial potency than the previous QADM. DMADDM-containing bonding agent was effective in eradicating bacteria in dentin, and its efficacy was directly proportional to DMADDM mass fraction. Therefore, DMADDM may be promising for use in bonding agents as well as in other restorative and preventive materials to inhibit bacteria. | Chen Chen Lei Cheng Michael D Weir Nancy J Lin Sheng Lin-Gibson Xue-Dong Zhou Hockin HK Xu | 2016 | International Journal of Oral Science2016，8，4： | 4 |
| 2 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 3 |
| 3 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 2 |
| 4 | Global malaria mortality between 1980 and 2010: a systematic analysis显示文摘 | Christopher JL Murray Lisa C Rosenfeld Stephen S Lim Kathryn G Andrews Kyle J Foreman Diana Haring Nancy Fullman Mohsen Naghavi Rafael Lozano Alan D Lopez | 2012 | The Lancet2012，，9814： | 2 |
| 5 | Bone sialoprotein mRNA expression and ultrastructural localization in fetal porcine calvarial bone: comparisons with osteopontin 显示文摘 | CHEN J MCKEE M D NANCI A | 1994 | Histochem J1994，26，1： | 1 |
| 6 | Phenotypic and molecular detection of CTX-M-lactamases produced by Escherichia coli and klebsiella spp显示文摘 | Johann D D Pitout Nancy D Hanson | 2004 | Clinical Microbiol2004，12，： | 1 |
| 7 | Parenting style as context:An integrative model显示文摘 | Nancy D Lawrence S | 1993 | Psychological Bulletin1993，13，3： | 1 |
| 8 | Analysis of cell wall neutral sugar composition, β-galactosidase activity and related cDNA clone throughout the development of Vitis vinifera grape berries 显示文摘 | Bamavon L Thierry D Nancy T | 2000 | Plant Physiol Biochem2000，38，4： | 1 |
| 9 | The use of rheological techniques to elucidate durum wheat dough strength properties显示文摘 | NANCY M EDWARDS JAMES E D | 2002 | Tecnica Molitoria2002，53，： | 1 |
| 10 | The Sources, Fate, and Toxicity of Chemical Warfare Agent Degradation Products 显示文摘 | Nancy Munro Sylvia S TalmageGuy D | 1999 | Environmental Health Perspectives1999，107，12： | 1 |
| 11 | Intrahepatic Cholangiocarcinoma: Rising Frequency, Improved Survival, and Determinants of Outcome After Resection显示文摘 | Itaru Endo Mithat Gonen Adam C. Yopp Kimberly M. Dalal Qin Zhou David Klimstra Michael D?Angelica Ronald P. DeMatteo Yuman Fong Lawrence Schwartz Nancy Kemeny Eileen O?Reilly Ghassan K. Abou-Alfa Hiroshi Shimada Leslie H. Blumgart William R. Jarnagin | 2008 | Annals of Surgery2008，，1： | 1 |
| 12 | Injection of human primary effusion lymphoma cells or associated macrophages into severe combined immunodeficient mice causes murine lymphomas 显示文摘 | Elisabeth Z Nancy W A Mark D W | 2002 | Cancer Res2002，62，： | 1 |
| 13 | Feeding bioassay for stored -product insect pestsusing an encapsulated food source显示文摘 | NANCY D | 2002 | Journal of Stored Prod-ucts Research2002，，38： | 1 |
| 14 | Molecular and phenotypic characterization of Als1 and Als2 mutations conferring tolerance to acetolactate synthase herbicides in soybean显示文摘 | Kay L Walter Stephen D Strachan Nancy M Ferry Henrik H Albert Linda A Castle Scott A Sebastian | 2014 | Pest. Manag. Sci2014，，12： | 1 |
| 15 | Gain of the 3q26 region in cervicovaginal liquid-based pap preparations is associated with squamous intraepithelial lesions and squamous cell carcinoma显示文摘 | Nancy P Caraway AK Marilyn D | 2008 | Gynecologic Oncology2008，110，： | 1 |
| 16 | Preoperative transcatheter closptal defects of congenital muscular ventricular septal defects 显示文摘 | BRIDGES NANCY D PERRY STANTON B KEANE JOHN F | 1991 | N Eng Med1991，324，： | 1 |
| 17 | Stress-induced phenylpropanoid metabolism显示文摘 | RICHARD A D NANCY L P | 1995 | The Plant Cell1995，7，： | 1 |
| 18 | Genetieally Engineered Saccharomyces Yeast Capable of Effective Cofermentation of Glucose and Xylose显示文摘 | Nancy W Y Chen Z D Adam | 1998 | Appl Environ Mierobiol1998，64，5： | 1 |
| 19 | The Vanderbilt Professional nursing prac-tice program,part 2显示文摘 | Nancy O Hara Mary D | 2003 | Journal of Nursing Advance2003，33，10： | 1 |
| 20 | The Association Between Low Birth Weight and Type 2 Diabetes: Contribution of Genetic Factors显示文摘 | Stefan Johansson Anastasia Iliadou Niklas Bergvall Ulf dé Fairé Michael S. Kramer Yudi Pawitan Nancy L. Pedersen Mikael Norman Paul Lichtenstein Sven Cnattingius | 2008 | Epidemiology2008，，5： | 1 |
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